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The map label for this gene is erg3 [H]

Identifier: 17230150

GI number: 17230150

Start: 3224600

End: 3225445

Strand: Reverse

Name: erg3 [H]

Synonym: all2658

Alternate gene names: 17230150

Gene position: 3225445-3224600 (Counterclockwise)

Preceding gene: 17230153

Following gene: 17230149

Centisome position: 50.29

GC content: 36.41

Gene sequence:

>846_bases
ATGGAATGGATGGGTGCTATCTTCAGCTTTGTGGAATATGTGCTGAAGGGAATGCTAATGTATGGCGTATTTATTGTAAT
AGAAAGAGTGCGTCCAGCCGAACCAAATCAACCATTTCGCCATATTATTTTCAACTTAAAATGGTATATTGTCTATCTTT
TGTTGGCATTTGGAATGAATGCCCTTGGTTTAGCTGCACTAGTGGGATTAACACGCAGTTGGCTAGGTGGAGCTTATCTA
AATTTTCCAGCACCCCGCAACTGGATAGAAACAATTATCGGGATCATTCTGTATTTCTTAATAGTTGACTTTTTCTACTA
TTGGTTTCACCGACTACAACACACAAATTCATTTTTATGGGGACAACATAAATTTCATCACAGTGAAGTTTCCTTAAATG
TTACCAGTTCCAGAAGAATACATTGGCTAGAAGAACCCTTAGTTCTCTTCTTCATAATTCTTCCCATGAATTTATTATTT
AATCTTCAACCGATAGCAGCAGGTTTATTAGCCTTTATAGAAATTTTGTGGTTGCAATTTATTCACATGAATTTACGTTT
AGGATTTGGTATTTTCTCAACCATAATTGTTAGTCCACAATACCACAGAATCCATCACTCATTTCAACCCCAACATATTA
ATAAAAACTATGCCGTATTCTTCCCGATTTGGGACATAGTTTTTGGTTCTTATTGTCATCCCCAACCAGGTGAGTTTCCA
GCCACCGGACTAACAACCAAGGAAACCTATAATCATCTCTGGAAAGCTTCTATTTTACCTTTTCAAGAATGGTATAAGTT
AATCATATTAAAACGTAGTTGTAGTGGACTGACACGACTGAAATAG

Upstream 100 bases:

>100_bases
TAAATTTGCAACTAATTGAGATAGACTTATGGTAAATTAATACAATCACCACAAAATCGTAAAATTCATTTTCTCTACAC
AAGAAATAGGTTAATTCATC

Downstream 100 bases:

>100_bases
TGCAATAATGCAGTTTTTGTGGTGTGGTCATGGGCATTTGGCCTGCACCATTATCTTGTGCAATTACAACCTTTGGCGGA
ATTACAGATCCAGAAGTTTC

Product: hypothetical protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MEWMGAIFSFVEYVLKGMLMYGVFIVIERVRPAEPNQPFRHIIFNLKWYIVYLLLAFGMNALGLAALVGLTRSWLGGAYL
NFPAPRNWIETIIGIILYFLIVDFFYYWFHRLQHTNSFLWGQHKFHHSEVSLNVTSSRRIHWLEEPLVLFFIILPMNLLF
NLQPIAAGLLAFIEILWLQFIHMNLRLGFGIFSTIIVSPQYHRIHHSFQPQHINKNYAVFFPIWDIVFGSYCHPQPGEFP
ATGLTTKETYNHLWKASILPFQEWYKLIILKRSCSGLTRLK

Sequences:

>Translated_281_residues
MEWMGAIFSFVEYVLKGMLMYGVFIVIERVRPAEPNQPFRHIIFNLKWYIVYLLLAFGMNALGLAALVGLTRSWLGGAYL
NFPAPRNWIETIIGIILYFLIVDFFYYWFHRLQHTNSFLWGQHKFHHSEVSLNVTSSRRIHWLEEPLVLFFIILPMNLLF
NLQPIAAGLLAFIEILWLQFIHMNLRLGFGIFSTIIVSPQYHRIHHSFQPQHINKNYAVFFPIWDIVFGSYCHPQPGEFP
ATGLTTKETYNHLWKASILPFQEWYKLIILKRSCSGLTRLK
>Mature_281_residues
MEWMGAIFSFVEYVLKGMLMYGVFIVIERVRPAEPNQPFRHIIFNLKWYIVYLLLAFGMNALGLAALVGLTRSWLGGAYL
NFPAPRNWIETIIGIILYFLIVDFFYYWFHRLQHTNSFLWGQHKFHHSEVSLNVTSSRRIHWLEEPLVLFFIILPMNLLF
NLQPIAAGLLAFIEILWLQFIHMNLRLGFGIFSTIIVSPQYHRIHHSFQPQHINKNYAVFFPIWDIVFGSYCHPQPGEFP
ATGLTTKETYNHLWKASILPFQEWYKLIILKRSCSGLTRLK

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=143, Percent_Identity=33.5664335664336, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25144659, Length=170, Percent_Identity=27.6470588235294, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 33140; Mature: 33140

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWMGAIFSFVEYVLKGMLMYGVFIVIERVRPAEPNQPFRHIIFNLKWYIVYLLLAFGMN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
ALGLAALVGLTRSWLGGAYLNFPAPRNWIETIIGIILYFLIVDFFYYWFHRLQHTNSFLW
HHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHC
GQHKFHHSEVSLNVTSSRRIHWLEEPLVLFFIILPMNLLFNLQPIAAGLLAFIEILWLQF
CCCCEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IHMNLRLGFGIFSTIIVSPQYHRIHHSFQPQHINKNYAVFFPIWDIVFGSYCHPQPGEFP
HHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCEEEEEEHHHHHHCCCCCCCCCCCC
ATGLTTKETYNHLWKASILPFQEWYKLIILKRSCSGLTRLK
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEWMGAIFSFVEYVLKGMLMYGVFIVIERVRPAEPNQPFRHIIFNLKWYIVYLLLAFGMN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
ALGLAALVGLTRSWLGGAYLNFPAPRNWIETIIGIILYFLIVDFFYYWFHRLQHTNSFLW
HHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHC
GQHKFHHSEVSLNVTSSRRIHWLEEPLVLFFIILPMNLLFNLQPIAAGLLAFIEILWLQF
CCCCEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IHMNLRLGFGIFSTIIVSPQYHRIHHSFQPQHINKNYAVFFPIWDIVFGSYCHPQPGEFP
HHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCEEEEEEHHHHHHCCCCCCCCCCCC
ATGLTTKETYNHLWKASILPFQEWYKLIILKRSCSGLTRLK
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]