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The map label for this gene is lgrC [H]

Identifier: 17230135

GI number: 17230135

Start: 3163531

End: 3166839

Strand: Reverse

Name: lgrC [H]

Synonym: all2643

Alternate gene names: 17230135

Gene position: 3166839-3163531 (Counterclockwise)

Preceding gene: 17230136

Following gene: 17230134

Centisome position: 49.38

GC content: 39.29

Gene sequence:

>3309_bases
ATGCAACCTGTGGATAAACGCAAAAATATAGAAAATATCTATCCCCTATCACCCATGCAGCAAGGAATGCTGTTTCATAC
CTTGCTAACCCCCCAAGCAGGGGTATATGTGCCACAGGTTTGCTTGTATCTGGAAGGAAAACTAGATATAAACGCCTTAA
AAACTGCATGGAATCAAGTTGTAATTAACCATCCAGCTTTACGCACAGCCTTTTATTGGGAACAGCGAGATAAACCCTTT
CAAGTTGTATTTCGCCAAGTAGAAATACCTTGGAAAATTTTAGATTGGCAGACAATATCTGATGCGGAACAGCAAGTAGA
ATTAGAGATTTTTTTGGAGAGCGATCGCACCTTCTCCTTCGACATCAAACAACCTCCATTATTACGTTTAACCCTAATTC
AATTATCAGCAACTAAATATATTCTTATCTGGACACAACATCATTTAATTCTCGATGGTTGGTCATCAGCATTAGTAATT
AAAGAAGTATTTCAAAATTATTATAATTCCCCATCTTATTATCCTAATTCCCGCCCCTACGGTGACTACATAGCTTGGTT
ACAACAACAAGATAAAATTGCCGCTAAAACATTCTGGCAAAAACAACTTGCAGGATTTACTACACCCACTGTCATACAAC
GATTTGCCCAAAGAGAAAACAAAAACCTCACACCCCAAGAACAAACCCGCAGTCTCACCCCGAATCAAACAACTGGGTTG
CAACAATGGGCAAAAGAGCAACAATTAACCCTGAATACTCTCTTACAGGGTGCTTTTGCCTTATTATTAAGCCGCTATTG
CAACACCACCGATGTAGTCTTTGGTGCAACCTCATCAGGACGACCCGCAACCCTCGCTGGTGTAGAGTCAATGGTGGGAT
TATTTATCAATACTTTGCCGGTGCGGGTTCAGGTATCACCCACAGATGATTTAGTTGAGTGGTTGCAAAAATTACAAGCA
CAACAAGCAGAAGCTCTAGAATATGAATATACATCACTCTTAGAAATTCAAGAATGGAGCGAACTTACACCAGGAACTTC
ATTATTTGACAGTATTTTAGTATTTGAAAATTATCCCGTTGATACATCGGGAATTTCCCAAAACCAAGATTTACGTATTA
TTGATATTCAATCTTTAGAATGGACAAGTTTTCCCTTAACCATGTTGGTTTCTGTAGGGAATCAATTGTCATTAAAAGTA
AAATATGACCGCAACAGATTTACAGATAATGCCATCACTCAATTATTAGAGCATTTCTGTAATTTGTTATTAGGAATGAG
TCAACCAGGGCAAACAATAGGAAACCTACCTTTATTAACTCAGCAAGAGTATGAAACCATCCACAAATGGAATCAAACAG
AAGCATATTATCCCCTAGAATGTATTCATCAGCAATTTGACATCCAGGTAGAAAGAACACCCGATGATGTTGCTGTGGTC
TTTGAGGAACAACAACTTACCTATAGAGAATTAAATCAACGTGCTAATCAATTAGCTCATTATTTGCAAACCTGGGGAGT
ACAACCAGAAACACCAGTTGGGATTTATATTGAACGTTCTTTAGAAATGGTCATTGGGATTTTAGGTATCCTCAAAGCTG
GAGGTTGTTATGTTCCTCTTGACCCTGCTTATCCTGCATCTAGGTTGACATATATTATTAATGAAACTCAAGTCCCAGTA
GTATTAACTCAGGAAAGTTTATTAGAAAAATTGCTAGGGTTTACCTCTTCCCAAGCCTCCAGCAAAGTATTGAATAAAAC
CTTGTGCTTATGCTTAGATACAGATTGGCAGGAAATCACCCAGAAACCTGACAATAATCCCATCACAAATGTTAATCATG
AAGATGCAATTTATATTATCTATACCTCTGGTTCTACAGGCACACCCAAGGGAGTAATTAACACCCATCGCGGTGTGAGT
AATCGATTGTATTGGATGCAGCAACAGTATGGTTTAGAAAGAGGAGAAGTTGTTTTACAAAAAACTCCCTTTAGTTTTGA
TGTTTCAGTGTGGGAATTTTTCTGGACATTACTAAATGGTGGTCGTTTGGTGATGTCTAAACCAGGAGGACATCAAGATC
CAAATTATTTATTAGAAATTATTGCACAGCACAAGATCACGACATTACACTTTGTGCCGACGATGTTAGGAGTGTTTTTA
GAAGCACCAAATTTAAATGAACGTTGTCACAGCTTGAAGCGGGTAATTTGTAGCGGTGAAGCTTTATCAATAGAAATTCA
AAATCGTTTCTTCCAGCATTTGGATGCAGAATTACACAATTTATATGGGCCGACAGAAGCCGCAATTGATGTCACATATT
GGCAATGTCAGCCTACAGATAATTTACATACAGTGCCTATCGGTCGTCCAATTACTAACACCCAAATTTACCTTTTAAAT
GATTATTTACAACCAGTACCTTTAGGTATTCCAGGTGAAATTTACATCGGTGGTGTAGGAGTCGCCAGAGGTTATTGGAA
ACGTCCAGATTTAACGACGGAAAGGTTTGTTGGGGGACTGGGGACTGGGGACTGGGGACTGGGGACTGGGGAAAAAAATA
ACCCAACTCTCAACTCCCAACTCAGCACTCAGCACTCAGCACTCAGCACTCTCTATAAAACAGGCGACCTTGCTCGCTAT
TTGCCTGATGGTAATTTAGAATACTTGGGGCGATTGGATAATCAGGTAAAAATTCGGGGGTTGAGGATTGAATTAGGGGA
AATTGAAGCGGTAATTAATCAACATCCTGATGTACAGCAAGCGGTGGTGATTTTAGACTCAAAACAAGCTGATAATCAGC
GTTTAGGGGCTTATGTGGTGCAGAAATCAACTAGCCTTGAGTCGCCAGATTTCACCAGCGAATTAGAAAAATTGTTGGCA
TCTCAATTACCAGAATATATGTTGCCTTCTGTATTTGTGATGTTGTCAGAATTACCTTTATTGCCTAACGGTAAAATCAA
TCGTCAAGCTTTACCGACACCTGAAACTGTACGCCATGCAAATCAATCTTATATTGCACCGCGTAATTCTACAGAAACAA
TTATTGCCAACATTTTGGCCGATGTGTTGCGACTAGAACGCATGGGAGTAGATGAAAACTTCTTTGAATTGGGGGGAAAT
TCCCTTTCAGCAATTCGGGTGACATCAAGACTCAGAGAAGCTTTTCAATTGGATTTACCTTTACATAGTGTATTTGAAAA
ACCCACAATTGCCGGACTTGCAGAACGAATTATGATTCTGCAACAGAGTATTCAACAAATGCAAACTACCCCGTCTGAAC
AATCAGGTCGTAAGGAGATATCGCTATGA

Upstream 100 bases:

>100_bases
GGAGGTAACGCAAAGGTACGCAGAGTTCTCTTACTCTCTGTGTCTCTGCGCCTCTGCGTGAGCCTAATTAAATACTTGCA
TCACAACATTACCAAAAATC

Downstream 100 bases:

>100_bases
AAACTATTGAAAAATTTCTGGCACACCTTTACAGCCTTGATGTTAAATTGTGGGTAGAAGATGCTAATTTACGGTGTAGT
ATTCCTGAAGATGTGCTGAC

Product: microcystin synthetase B

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1102; Mature: 1102

Protein sequence:

>1102_residues
MQPVDKRKNIENIYPLSPMQQGMLFHTLLTPQAGVYVPQVCLYLEGKLDINALKTAWNQVVINHPALRTAFYWEQRDKPF
QVVFRQVEIPWKILDWQTISDAEQQVELEIFLESDRTFSFDIKQPPLLRLTLIQLSATKYILIWTQHHLILDGWSSALVI
KEVFQNYYNSPSYYPNSRPYGDYIAWLQQQDKIAAKTFWQKQLAGFTTPTVIQRFAQRENKNLTPQEQTRSLTPNQTTGL
QQWAKEQQLTLNTLLQGAFALLLSRYCNTTDVVFGATSSGRPATLAGVESMVGLFINTLPVRVQVSPTDDLVEWLQKLQA
QQAEALEYEYTSLLEIQEWSELTPGTSLFDSILVFENYPVDTSGISQNQDLRIIDIQSLEWTSFPLTMLVSVGNQLSLKV
KYDRNRFTDNAITQLLEHFCNLLLGMSQPGQTIGNLPLLTQQEYETIHKWNQTEAYYPLECIHQQFDIQVERTPDDVAVV
FEEQQLTYRELNQRANQLAHYLQTWGVQPETPVGIYIERSLEMVIGILGILKAGGCYVPLDPAYPASRLTYIINETQVPV
VLTQESLLEKLLGFTSSQASSKVLNKTLCLCLDTDWQEITQKPDNNPITNVNHEDAIYIIYTSGSTGTPKGVINTHRGVS
NRLYWMQQQYGLERGEVVLQKTPFSFDVSVWEFFWTLLNGGRLVMSKPGGHQDPNYLLEIIAQHKITTLHFVPTMLGVFL
EAPNLNERCHSLKRVICSGEALSIEIQNRFFQHLDAELHNLYGPTEAAIDVTYWQCQPTDNLHTVPIGRPITNTQIYLLN
DYLQPVPLGIPGEIYIGGVGVARGYWKRPDLTTERFVGGLGTGDWGLGTGEKNNPTLNSQLSTQHSALSTLYKTGDLARY
LPDGNLEYLGRLDNQVKIRGLRIELGEIEAVINQHPDVQQAVVILDSKQADNQRLGAYVVQKSTSLESPDFTSELEKLLA
SQLPEYMLPSVFVMLSELPLLPNGKINRQALPTPETVRHANQSYIAPRNSTETIIANILADVLRLERMGVDENFFELGGN
SLSAIRVTSRLREAFQLDLPLHSVFEKPTIAGLAERIMILQQSIQQMQTTPSEQSGRKEISL

Sequences:

>Translated_1102_residues
MQPVDKRKNIENIYPLSPMQQGMLFHTLLTPQAGVYVPQVCLYLEGKLDINALKTAWNQVVINHPALRTAFYWEQRDKPF
QVVFRQVEIPWKILDWQTISDAEQQVELEIFLESDRTFSFDIKQPPLLRLTLIQLSATKYILIWTQHHLILDGWSSALVI
KEVFQNYYNSPSYYPNSRPYGDYIAWLQQQDKIAAKTFWQKQLAGFTTPTVIQRFAQRENKNLTPQEQTRSLTPNQTTGL
QQWAKEQQLTLNTLLQGAFALLLSRYCNTTDVVFGATSSGRPATLAGVESMVGLFINTLPVRVQVSPTDDLVEWLQKLQA
QQAEALEYEYTSLLEIQEWSELTPGTSLFDSILVFENYPVDTSGISQNQDLRIIDIQSLEWTSFPLTMLVSVGNQLSLKV
KYDRNRFTDNAITQLLEHFCNLLLGMSQPGQTIGNLPLLTQQEYETIHKWNQTEAYYPLECIHQQFDIQVERTPDDVAVV
FEEQQLTYRELNQRANQLAHYLQTWGVQPETPVGIYIERSLEMVIGILGILKAGGCYVPLDPAYPASRLTYIINETQVPV
VLTQESLLEKLLGFTSSQASSKVLNKTLCLCLDTDWQEITQKPDNNPITNVNHEDAIYIIYTSGSTGTPKGVINTHRGVS
NRLYWMQQQYGLERGEVVLQKTPFSFDVSVWEFFWTLLNGGRLVMSKPGGHQDPNYLLEIIAQHKITTLHFVPTMLGVFL
EAPNLNERCHSLKRVICSGEALSIEIQNRFFQHLDAELHNLYGPTEAAIDVTYWQCQPTDNLHTVPIGRPITNTQIYLLN
DYLQPVPLGIPGEIYIGGVGVARGYWKRPDLTTERFVGGLGTGDWGLGTGEKNNPTLNSQLSTQHSALSTLYKTGDLARY
LPDGNLEYLGRLDNQVKIRGLRIELGEIEAVINQHPDVQQAVVILDSKQADNQRLGAYVVQKSTSLESPDFTSELEKLLA
SQLPEYMLPSVFVMLSELPLLPNGKINRQALPTPETVRHANQSYIAPRNSTETIIANILADVLRLERMGVDENFFELGGN
SLSAIRVTSRLREAFQLDLPLHSVFEKPTIAGLAERIMILQQSIQQMQTTPSEQSGRKEISL
>Mature_1102_residues
MQPVDKRKNIENIYPLSPMQQGMLFHTLLTPQAGVYVPQVCLYLEGKLDINALKTAWNQVVINHPALRTAFYWEQRDKPF
QVVFRQVEIPWKILDWQTISDAEQQVELEIFLESDRTFSFDIKQPPLLRLTLIQLSATKYILIWTQHHLILDGWSSALVI
KEVFQNYYNSPSYYPNSRPYGDYIAWLQQQDKIAAKTFWQKQLAGFTTPTVIQRFAQRENKNLTPQEQTRSLTPNQTTGL
QQWAKEQQLTLNTLLQGAFALLLSRYCNTTDVVFGATSSGRPATLAGVESMVGLFINTLPVRVQVSPTDDLVEWLQKLQA
QQAEALEYEYTSLLEIQEWSELTPGTSLFDSILVFENYPVDTSGISQNQDLRIIDIQSLEWTSFPLTMLVSVGNQLSLKV
KYDRNRFTDNAITQLLEHFCNLLLGMSQPGQTIGNLPLLTQQEYETIHKWNQTEAYYPLECIHQQFDIQVERTPDDVAVV
FEEQQLTYRELNQRANQLAHYLQTWGVQPETPVGIYIERSLEMVIGILGILKAGGCYVPLDPAYPASRLTYIINETQVPV
VLTQESLLEKLLGFTSSQASSKVLNKTLCLCLDTDWQEITQKPDNNPITNVNHEDAIYIIYTSGSTGTPKGVINTHRGVS
NRLYWMQQQYGLERGEVVLQKTPFSFDVSVWEFFWTLLNGGRLVMSKPGGHQDPNYLLEIIAQHKITTLHFVPTMLGVFL
EAPNLNERCHSLKRVICSGEALSIEIQNRFFQHLDAELHNLYGPTEAAIDVTYWQCQPTDNLHTVPIGRPITNTQIYLLN
DYLQPVPLGIPGEIYIGGVGVARGYWKRPDLTTERFVGGLGTGDWGLGTGEKNNPTLNSQLSTQHSALSTLYKTGDLARY
LPDGNLEYLGRLDNQVKIRGLRIELGEIEAVINQHPDVQQAVVILDSKQADNQRLGAYVVQKSTSLESPDFTSELEKLLA
SQLPEYMLPSVFVMLSELPLLPNGKINRQALPTPETVRHANQSYIAPRNSTETIIANILADVLRLERMGVDENFFELGGN
SLSAIRVTSRLREAFQLDLPLHSVFEKPTIAGLAERIMILQQSIQQMQTTPSEQSGRKEISL

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=650, Percent_Identity=25.0769230769231, Blast_Score=113, Evalue=1e-24,
Organism=Homo sapiens, GI13375727, Length=579, Percent_Identity=22.6252158894646, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI42544132, Length=538, Percent_Identity=20.4460966542751, Blast_Score=94, Evalue=5e-19,
Organism=Escherichia coli, GI1786801, Length=1007, Percent_Identity=31.0824230387289, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI1788107, Length=568, Percent_Identity=25.1760563380282, Blast_Score=129, Evalue=1e-30,
Organism=Escherichia coli, GI145693145, Length=537, Percent_Identity=24.0223463687151, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786810, Length=545, Percent_Identity=23.302752293578, Blast_Score=106, Evalue=7e-24,
Organism=Escherichia coli, GI221142682, Length=522, Percent_Identity=22.6053639846743, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17550940, Length=1075, Percent_Identity=21.2093023255814, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17558820, Length=515, Percent_Identity=22.3300970873786, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32563687, Length=529, Percent_Identity=22.117202268431, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17557194, Length=551, Percent_Identity=25.0453720508167, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17538037, Length=563, Percent_Identity=23.0905861456483, Blast_Score=101, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17556356, Length=592, Percent_Identity=22.972972972973, Blast_Score=97, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17560140, Length=501, Percent_Identity=21.3572854291417, Blast_Score=93, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17560308, Length=569, Percent_Identity=20.3866432337434, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71983001, Length=578, Percent_Identity=20.9342560553633, Blast_Score=80, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71982997, Length=578, Percent_Identity=20.9342560553633, Blast_Score=80, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71996755, Length=550, Percent_Identity=22, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17531443, Length=552, Percent_Identity=21.195652173913, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=811, Percent_Identity=25.77065351418, Blast_Score=251, Evalue=4e-67,
Organism=Saccharomyces cerevisiae, GI6319264, Length=572, Percent_Identity=24.4755244755245, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6319699, Length=562, Percent_Identity=21.5302491103203, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24648676, Length=641, Percent_Identity=30.8892355694228, Blast_Score=254, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24581924, Length=567, Percent_Identity=23.1040564373898, Blast_Score=120, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24583465, Length=556, Percent_Identity=22.1223021582734, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24583463, Length=556, Percent_Identity=22.1223021582734, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281364798, Length=559, Percent_Identity=22.1824686940966, Blast_Score=74, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 124967; Mature: 124967

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPVDKRKNIENIYPLSPMQQGMLFHTLLTPQAGVYVPQVCLYLEGKLDINALKTAWNQV
CCCCCCCCCCCCCCCCCHHHHCCEEEHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHE
VINHPALRTAFYWEQRDKPFQVVFRQVEIPWKILDWQTISDAEQQVELEIFLESDRTFSF
EECCCHHHHHEEHHCCCCHHHHHHHHHCCCEEEECCCCCCCHHHCEEEEEEEECCCEEEE
DIKQPPLLRLTLIQLSATKYILIWTQHHLILDGWSSALVIKEVFQNYYNSPSYYPNSRPY
ECCCCCEEEEEEEEECCCEEEEEEEECEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCC
GDYIAWLQQQDKIAAKTFWQKQLAGFTTPTVIQRFAQRENKNLTPQEQTRSLTPNQTTGL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHH
QQWAKEQQLTLNTLLQGAFALLLSRYCNTTDVVFGATSSGRPATLAGVESMVGLFINTLP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCE
VRVQVSPTDDLVEWLQKLQAQQAEALEYEYTSLLEIQEWSELTPGTSLFDSILVFENYPV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEECCCC
DTSGISQNQDLRIIDIQSLEWTSFPLTMLVSVGNQLSLKVKYDRNRFTDNAITQLLEHFC
CCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHH
NLLLGMSQPGQTIGNLPLLTQQEYETIHKWNQTEAYYPLECIHQQFDIQVERTPDDVAVV
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCEEEECCCCCEEEE
FEEQQLTYRELNQRANQLAHYLQTWGVQPETPVGIYIERSLEMVIGILGILKAGGCYVPL
EECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEC
DPAYPASRLTYIINETQVPVVLTQESLLEKLLGFTSSQASSKVLNKTLCLCLDTDWQEIT
CCCCCCCCEEEEEECCCCCEEECHHHHHHHHHCCCCCHHHHHHHHHEEEEEECCCHHHHH
QKPDNNPITNVNHEDAIYIIYTSGSTGTPKGVINTHRGVSNRLYWMQQQYGLERGEVVLQ
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEE
KTPFSFDVSVWEFFWTLLNGGRLVMSKPGGHQDPNYLLEIIAQHKITTLHFVPTMLGVFL
ECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
EAPNLNERCHSLKRVICSGEALSIEIQNRFFQHLDAELHNLYGPTEAAIDVTYWQCQPTD
CCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
NLHTVPIGRPITNTQIYLLNDYLQPVPLGIPGEIYIGGVGVARGYWKRPDLTTERFVGGL
CEEEEECCCCCCCCEEEEEECCCCCCCCCCCCEEEECCEECCCCCCCCCCCCHHHHHCCC
GTGDWGLGTGEKNNPTLNSQLSTQHSALSTLYKTGDLARYLPDGNLEYLGRLDNQVKIRG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHCCCCEEEEEE
LRIELGEIEAVINQHPDVQQAVVILDSKQADNQRLGAYVVQKSTSLESPDFTSELEKLLA
EEEEHHHHHHHHHCCCCHHHEEEEEECCCCCCCHHCEEEEECCCCCCCCCHHHHHHHHHH
SQLPEYMLPSVFVMLSELPLLPNGKINRQALPTPETVRHANQSYIAPRNSTETIIANILA
HHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHH
DVLRLERMGVDENFFELGGNSLSAIRVTSRLREAFQLDLPLHSVFEKPTIAGLAERIMIL
HHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHH
QQSIQQMQTTPSEQSGRKEISL
HHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQPVDKRKNIENIYPLSPMQQGMLFHTLLTPQAGVYVPQVCLYLEGKLDINALKTAWNQV
CCCCCCCCCCCCCCCCCHHHHCCEEEHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHE
VINHPALRTAFYWEQRDKPFQVVFRQVEIPWKILDWQTISDAEQQVELEIFLESDRTFSF
EECCCHHHHHEEHHCCCCHHHHHHHHHCCCEEEECCCCCCCHHHCEEEEEEEECCCEEEE
DIKQPPLLRLTLIQLSATKYILIWTQHHLILDGWSSALVIKEVFQNYYNSPSYYPNSRPY
ECCCCCEEEEEEEEECCCEEEEEEEECEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCC
GDYIAWLQQQDKIAAKTFWQKQLAGFTTPTVIQRFAQRENKNLTPQEQTRSLTPNQTTGL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHH
QQWAKEQQLTLNTLLQGAFALLLSRYCNTTDVVFGATSSGRPATLAGVESMVGLFINTLP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCE
VRVQVSPTDDLVEWLQKLQAQQAEALEYEYTSLLEIQEWSELTPGTSLFDSILVFENYPV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEECCCC
DTSGISQNQDLRIIDIQSLEWTSFPLTMLVSVGNQLSLKVKYDRNRFTDNAITQLLEHFC
CCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHH
NLLLGMSQPGQTIGNLPLLTQQEYETIHKWNQTEAYYPLECIHQQFDIQVERTPDDVAVV
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCEEEECCCCCEEEE
FEEQQLTYRELNQRANQLAHYLQTWGVQPETPVGIYIERSLEMVIGILGILKAGGCYVPL
EECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEC
DPAYPASRLTYIINETQVPVVLTQESLLEKLLGFTSSQASSKVLNKTLCLCLDTDWQEIT
CCCCCCCCEEEEEECCCCCEEECHHHHHHHHHCCCCCHHHHHHHHHEEEEEECCCHHHHH
QKPDNNPITNVNHEDAIYIIYTSGSTGTPKGVINTHRGVSNRLYWMQQQYGLERGEVVLQ
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEE
KTPFSFDVSVWEFFWTLLNGGRLVMSKPGGHQDPNYLLEIIAQHKITTLHFVPTMLGVFL
ECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
EAPNLNERCHSLKRVICSGEALSIEIQNRFFQHLDAELHNLYGPTEAAIDVTYWQCQPTD
CCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
NLHTVPIGRPITNTQIYLLNDYLQPVPLGIPGEIYIGGVGVARGYWKRPDLTTERFVGGL
CEEEEECCCCCCCCEEEEEECCCCCCCCCCCCEEEECCEECCCCCCCCCCCCHHHHHCCC
GTGDWGLGTGEKNNPTLNSQLSTQHSALSTLYKTGDLARYLPDGNLEYLGRLDNQVKIRG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHCCCCEEEEEE
LRIELGEIEAVINQHPDVQQAVVILDSKQADNQRLGAYVVQKSTSLESPDFTSELEKLLA
EEEEHHHHHHHHHCCCCHHHEEEEEECCCCCCCHHCEEEEECCCCCCCCCHHHHHHHHHH
SQLPEYMLPSVFVMLSELPLLPNGKINRQALPTPETVRHANQSYIAPRNSTETIIANILA
HHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHH
DVLRLERMGVDENFFELGGNSLSAIRVTSRLREAFQLDLPLHSVFEKPTIAGLAERIMIL
HHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHH
QQSIQQMQTTPSEQSGRKEISL
HHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA