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The map label for this gene is lgrC [H]

Identifier: 17230134

GI number: 17230134

Start: 3160040

End: 3163534

Strand: Reverse

Name: lgrC [H]

Synonym: all2642

Alternate gene names: 17230134

Gene position: 3163534-3160040 (Counterclockwise)

Preceding gene: 17230135

Following gene: 17230133

Centisome position: 49.32

GC content: 41.8

Gene sequence:

>3495_bases
ATGAAAACTATTGAAAAATTTCTGGCACACCTTTACAGCCTTGATGTTAAATTGTGGGTAGAAGATGCTAATTTACGGTG
TAGTATTCCTGAAGATGTGCTGACGGATGAACTGACTGGAGAATTGCGATCGCGCAAATCTGAAATCATCACTTTTTTAC
GTCAAGCTAAGTCATCTACAAATTATACACAAGCAATTACCCCAGCACCACGCAACGGCAACCTACCTCTGTCTTTTGCT
CAACAAAGATTGTGGTTTTTAGAACAATTACAACCCGATAGTTATACTTATAATTTACCGACAGCAGTCAGATTGACGGG
GATTTTGGATGTTGGATTATTGGAGCGATCGCTAAATACCATTATCCAACGTCATGAGCTACTACGCACAAACTTCAAAA
CTGTAGATGGAAATCCTGTTTTAGATATTCAGCCGAGTGTCACCCTTCCCCTGGCTGTGATAGATTTACAAGCCTTTAAT
CTCCTCGAACAAGATGAAGAAGTCCGTCACCTGGCTTTAAAAGAAGCACAAACACCTTTTGATTTAGCCACAGATGTATT
ATTGCGGGTGAAAATTCTCCAACTAGCTAAAGATGAAAATGTAGTTTTATTTACCATGCACCACATCGTTTCTGATGGTT
GGTCAATGGAAATTTTAGTTAAAGAATTAGCAACCCTTTATACTGCCTTTAGTGGTAATCAACCATCCCCTTTACCAGAG
TTAGCAATTCAGTATGTTGATTTTGCAATTTGGCAAAGACAATGGTTACAAGGAGAAGTTTTAGAAACTCAACTAGACTA
TTGGCGACAACAATTAGGCGGTATCCTCCCAGTATTACAATTACCCACCGACTACCCCCGTGGAAGAGTACAGACATTTC
GGGGTGCAATTGAATCTTTTTCTCTCTCTCCTCAATTGAGTCAAGGTATTATCAAACTCGCAAAAAATGCAGGTGTCACG
CCTTTTGTTACCCTCCTCACGGCTTATAAAATTCTCCTGCATCGCTATACCGGACAAACAGATATCCTCGTTGGGACTCC
CGTAGCTAATCGCCATCGTCGAGAAATAGAAGCTTTAATTGGCTTTTTTGTCAACACATTAGTATTGCGGACAAATTTAG
CAGATAATCCCAGTTTTCAGGAATTATTACAGCAGCTAATAAATACAACTTGGCAAGCTTACGACCATCAAGATATACCT
TTTGAAAAATTAGTAGAAGTCCTGCAACCGGAAAGAGATTTAAGTTTTAATCCACTATTTCAGGTAAAATTTCGGTTAGA
AAATGCCCCTACAGAAAAATTAGAATTACCAGGGTTAACTCTCAGACCTTTAAATCGGACAGAAGCAAGTGCCAAACTAG
ATTTAAGTTTGGATATGTACGAAACATCAGAGGGTTTTGTAGGTGCATTTGAATATAACCGAGATTTGTTTGCACCAGAG
ACAATTAACCGAATGGTAGGACATTTTCAAACGGTATTGACGGCGATTGTTGAGAATCCACAAAAACGGATTTCCGAATT
ACCATTACTGACAGATAAAGAAAAACAAACTATTCTCATTGATTGGAATCAAACCCAAGTAGAATGTCCTAGCCATTTAA
CCTTTCAAGACTTATTTGCAGCGCAGGTAGAAAAAACACCAGATGAAGTAGCGATTATCTTTGAAAATCAGTCTCTTACT
TACACAGAACTCAATCAAAAAAGTAATCAAGTTGCTCATTACCTCAAAAAAAAAGGGGTGAAACCAGAGGTAATTGTGGG
ATTATGTGTAGAGCGTTCCCCATTAATGATCATCGCTTTACTTGGTATCCTCAAAGCTGGTGGTGCATATCTCCCCCTCG
ACCCCAATTATCCCCCAGAACGCCTGGGGTATATGTTGGCTGATTCCCAAGTACCAATTTTACTAACAGAAACAAGCCTG
AAAGTTGCCACTTCCTCAAGCTACGAAATAATTTACCTAGATACAGACTGGGAAACAATTTCTCAATGCAGTATAGAAAA
CCCAGAAAGTGAAGTTAAACCAGAAAATTTAGCTTATTTAATTTACACCTCCGGTTCTACTGGTAAACCAAAAGGGGTTT
TAATCCCCCACATCGGCTTAACCAACCTCACACAACATAAAATACAAGTTTGTGATGTTCATCCCGGTGATTGTGTACTG
CAATTTTTCTCACTCAGCTTTGATGCTTCTATCCCCGAAATCATCATGGCTTTGGGAAGCGGTGCAAAACTTTGTCTAGC
CAAATCAGAATCTTTACTACCAGGAGAAACCTTACTAAAACTGCTACGGGACAACGCAGTTACTCATATAACTATCACCC
CCTCAGCCCTATCCCTACTCCCCTCAGCAGACTTACCACATTTGCGAATGGTACTAGTAGGAGGTGAAGCACCATCACCT
GAATTAATCGCCAAATGGTCACAAGGAAGACGTTTTATCAACGCTTACGGCCCAACGGAAGTTACAGTCAACGCCAGCAT
GGTACTTTGTGGAAACGGTCATCCCCTAGTTCCCACCATTCGCCCCAGTGCCAACAAACAACTATATATATTAGATAATT
ATTTACAACCCGTCCCCATCGGCGTAATTGGTGAACTCTACATTGGTGGAATAGGTTTAGCGCGAGGTTATCTAAATCGC
CCAGATTTAACAGCCGAAAGATTTATTAGGGACTGGGGACTGGGGACTGGGGACTGGGGACTGGGAAAAGAAGTGTCCTT
AGTCAACAGTCAACAGTCAACAGTCAACAGTGATTCCAGACTTTATAAAACCGGTGACTTAGCTTATTACTTACCTGATG
GTCGCATCAGACTTTTAGGAAGGGTTGATAACCAAGTCAAAATTCGCGGTTTTCGCATTGAACCGCAAGAAGTGGAAACC
TTATTATGTCAACATCCTGGGGTGCGTGCTGGAGTAGTAATTGTCCGCGAAGACCAACCAGGGGAGAAGCGTTTAGTCGC
CTACGTCATTCCCAATGAGGAAGGAGGGGAGCAAAAATTTCCCCAATCCCCAATCCCCAATCCCCAGTCCCCAATCCCCA
ATCCCCAATCCCTCCGAGCTTTCATGCGAGAGAAGTTACCCGAATATCTTGTTCCGTCGGCGTTTGTGCTACTGACTGAT
TTACCCCTGACACCCAACGGTAAAGTAGACACCCACGCACTCCCCGCACCCGAACAAGTCCTAGCAAACGCTGAATTTAT
CGCCCCCCGTACAGATATCGAAGCGCAATTAGCCGATATATACGCCCAGATACTCAAGTTAGAAAAGGTGAGTATTCAGG
ATGACTTTTTTGAATTGGGGGGACATTCTCTCATCGCCACTCAATTAATCGCCCAAGCTTTGCAGGTATTTCAAGTCGAA
CTTACCGTCATGGATTTGTTTGATGCACCAACAGTAGCAGGTTTAGCGGAACGAATTTTACAACGACAACTAAAGGCAGA
AATTCCAGTAATATCTGATACCAGCGATGATGAACGAGAGGAGTTTGAAATTTAA

Upstream 100 bases:

>100_bases
CAATTGCCGGACTTGCAGAACGAATTATGATTCTGCAACAGAGTATTCAACAAATGCAAACTACCCCGTCTGAACAATCA
GGTCGTAAGGAGATATCGCT

Downstream 100 bases:

>100_bases
CCATGACACAACCAATGTATCTCAAACCCAATGTCATCATTGAACCACTATTCAATCAGTGGTACGCCTGGTCATATTTA
ATTTCTCCCGCCACAGCCGC

Product: multifunctional peptide synthetase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1164; Mature: 1164

Protein sequence:

>1164_residues
MKTIEKFLAHLYSLDVKLWVEDANLRCSIPEDVLTDELTGELRSRKSEIITFLRQAKSSTNYTQAITPAPRNGNLPLSFA
QQRLWFLEQLQPDSYTYNLPTAVRLTGILDVGLLERSLNTIIQRHELLRTNFKTVDGNPVLDIQPSVTLPLAVIDLQAFN
LLEQDEEVRHLALKEAQTPFDLATDVLLRVKILQLAKDENVVLFTMHHIVSDGWSMEILVKELATLYTAFSGNQPSPLPE
LAIQYVDFAIWQRQWLQGEVLETQLDYWRQQLGGILPVLQLPTDYPRGRVQTFRGAIESFSLSPQLSQGIIKLAKNAGVT
PFVTLLTAYKILLHRYTGQTDILVGTPVANRHRREIEALIGFFVNTLVLRTNLADNPSFQELLQQLINTTWQAYDHQDIP
FEKLVEVLQPERDLSFNPLFQVKFRLENAPTEKLELPGLTLRPLNRTEASAKLDLSLDMYETSEGFVGAFEYNRDLFAPE
TINRMVGHFQTVLTAIVENPQKRISELPLLTDKEKQTILIDWNQTQVECPSHLTFQDLFAAQVEKTPDEVAIIFENQSLT
YTELNQKSNQVAHYLKKKGVKPEVIVGLCVERSPLMIIALLGILKAGGAYLPLDPNYPPERLGYMLADSQVPILLTETSL
KVATSSSYEIIYLDTDWETISQCSIENPESEVKPENLAYLIYTSGSTGKPKGVLIPHIGLTNLTQHKIQVCDVHPGDCVL
QFFSLSFDASIPEIIMALGSGAKLCLAKSESLLPGETLLKLLRDNAVTHITITPSALSLLPSADLPHLRMVLVGGEAPSP
ELIAKWSQGRRFINAYGPTEVTVNASMVLCGNGHPLVPTIRPSANKQLYILDNYLQPVPIGVIGELYIGGIGLARGYLNR
PDLTAERFIRDWGLGTGDWGLGKEVSLVNSQQSTVNSDSRLYKTGDLAYYLPDGRIRLLGRVDNQVKIRGFRIEPQEVET
LLCQHPGVRAGVVIVREDQPGEKRLVAYVIPNEEGGEQKFPQSPIPNPQSPIPNPQSLRAFMREKLPEYLVPSAFVLLTD
LPLTPNGKVDTHALPAPEQVLANAEFIAPRTDIEAQLADIYAQILKLEKVSIQDDFFELGGHSLIATQLIAQALQVFQVE
LTVMDLFDAPTVAGLAERILQRQLKAEIPVISDTSDDEREEFEI

Sequences:

>Translated_1164_residues
MKTIEKFLAHLYSLDVKLWVEDANLRCSIPEDVLTDELTGELRSRKSEIITFLRQAKSSTNYTQAITPAPRNGNLPLSFA
QQRLWFLEQLQPDSYTYNLPTAVRLTGILDVGLLERSLNTIIQRHELLRTNFKTVDGNPVLDIQPSVTLPLAVIDLQAFN
LLEQDEEVRHLALKEAQTPFDLATDVLLRVKILQLAKDENVVLFTMHHIVSDGWSMEILVKELATLYTAFSGNQPSPLPE
LAIQYVDFAIWQRQWLQGEVLETQLDYWRQQLGGILPVLQLPTDYPRGRVQTFRGAIESFSLSPQLSQGIIKLAKNAGVT
PFVTLLTAYKILLHRYTGQTDILVGTPVANRHRREIEALIGFFVNTLVLRTNLADNPSFQELLQQLINTTWQAYDHQDIP
FEKLVEVLQPERDLSFNPLFQVKFRLENAPTEKLELPGLTLRPLNRTEASAKLDLSLDMYETSEGFVGAFEYNRDLFAPE
TINRMVGHFQTVLTAIVENPQKRISELPLLTDKEKQTILIDWNQTQVECPSHLTFQDLFAAQVEKTPDEVAIIFENQSLT
YTELNQKSNQVAHYLKKKGVKPEVIVGLCVERSPLMIIALLGILKAGGAYLPLDPNYPPERLGYMLADSQVPILLTETSL
KVATSSSYEIIYLDTDWETISQCSIENPESEVKPENLAYLIYTSGSTGKPKGVLIPHIGLTNLTQHKIQVCDVHPGDCVL
QFFSLSFDASIPEIIMALGSGAKLCLAKSESLLPGETLLKLLRDNAVTHITITPSALSLLPSADLPHLRMVLVGGEAPSP
ELIAKWSQGRRFINAYGPTEVTVNASMVLCGNGHPLVPTIRPSANKQLYILDNYLQPVPIGVIGELYIGGIGLARGYLNR
PDLTAERFIRDWGLGTGDWGLGKEVSLVNSQQSTVNSDSRLYKTGDLAYYLPDGRIRLLGRVDNQVKIRGFRIEPQEVET
LLCQHPGVRAGVVIVREDQPGEKRLVAYVIPNEEGGEQKFPQSPIPNPQSPIPNPQSLRAFMREKLPEYLVPSAFVLLTD
LPLTPNGKVDTHALPAPEQVLANAEFIAPRTDIEAQLADIYAQILKLEKVSIQDDFFELGGHSLIATQLIAQALQVFQVE
LTVMDLFDAPTVAGLAERILQRQLKAEIPVISDTSDDEREEFEI
>Mature_1164_residues
MKTIEKFLAHLYSLDVKLWVEDANLRCSIPEDVLTDELTGELRSRKSEIITFLRQAKSSTNYTQAITPAPRNGNLPLSFA
QQRLWFLEQLQPDSYTYNLPTAVRLTGILDVGLLERSLNTIIQRHELLRTNFKTVDGNPVLDIQPSVTLPLAVIDLQAFN
LLEQDEEVRHLALKEAQTPFDLATDVLLRVKILQLAKDENVVLFTMHHIVSDGWSMEILVKELATLYTAFSGNQPSPLPE
LAIQYVDFAIWQRQWLQGEVLETQLDYWRQQLGGILPVLQLPTDYPRGRVQTFRGAIESFSLSPQLSQGIIKLAKNAGVT
PFVTLLTAYKILLHRYTGQTDILVGTPVANRHRREIEALIGFFVNTLVLRTNLADNPSFQELLQQLINTTWQAYDHQDIP
FEKLVEVLQPERDLSFNPLFQVKFRLENAPTEKLELPGLTLRPLNRTEASAKLDLSLDMYETSEGFVGAFEYNRDLFAPE
TINRMVGHFQTVLTAIVENPQKRISELPLLTDKEKQTILIDWNQTQVECPSHLTFQDLFAAQVEKTPDEVAIIFENQSLT
YTELNQKSNQVAHYLKKKGVKPEVIVGLCVERSPLMIIALLGILKAGGAYLPLDPNYPPERLGYMLADSQVPILLTETSL
KVATSSSYEIIYLDTDWETISQCSIENPESEVKPENLAYLIYTSGSTGKPKGVLIPHIGLTNLTQHKIQVCDVHPGDCVL
QFFSLSFDASIPEIIMALGSGAKLCLAKSESLLPGETLLKLLRDNAVTHITITPSALSLLPSADLPHLRMVLVGGEAPSP
ELIAKWSQGRRFINAYGPTEVTVNASMVLCGNGHPLVPTIRPSANKQLYILDNYLQPVPIGVIGELYIGGIGLARGYLNR
PDLTAERFIRDWGLGTGDWGLGKEVSLVNSQQSTVNSDSRLYKTGDLAYYLPDGRIRLLGRVDNQVKIRGFRIEPQEVET
LLCQHPGVRAGVVIVREDQPGEKRLVAYVIPNEEGGEQKFPQSPIPNPQSPIPNPQSLRAFMREKLPEYLVPSAFVLLTD
LPLTPNGKVDTHALPAPEQVLANAEFIAPRTDIEAQLADIYAQILKLEKVSIQDDFFELGGHSLIATQLIAQALQVFQVE
LTVMDLFDAPTVAGLAERILQRQLKAEIPVISDTSDDEREEFEI

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=658, Percent_Identity=23.2522796352584, Blast_Score=94, Evalue=1e-18,
Organism=Escherichia coli, GI1786801, Length=1102, Percent_Identity=28.4936479128857, Blast_Score=313, Evalue=3e-86,
Organism=Escherichia coli, GI1786810, Length=545, Percent_Identity=24.2201834862385, Blast_Score=107, Evalue=5e-24,
Organism=Escherichia coli, GI221142682, Length=517, Percent_Identity=22.4371373307544, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17550940, Length=1094, Percent_Identity=22.5776965265082, Blast_Score=172, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI17556356, Length=565, Percent_Identity=25.1327433628319, Blast_Score=133, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17560140, Length=495, Percent_Identity=22.2222222222222, Blast_Score=101, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17531443, Length=497, Percent_Identity=21.9315895372233, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32564420, Length=451, Percent_Identity=24.390243902439, Blast_Score=80, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32564422, Length=451, Percent_Identity=24.390243902439, Blast_Score=80, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17559526, Length=509, Percent_Identity=21.2180746561886, Blast_Score=79, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319591, Length=950, Percent_Identity=26.9473684210526, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24648676, Length=609, Percent_Identity=27.7504105090312, Blast_Score=173, Evalue=6e-43,
Organism=Drosophila melanogaster, GI18859661, Length=553, Percent_Identity=22.6039783001808, Blast_Score=89, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 130163; Mature: 130163

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIEKFLAHLYSLDVKLWVEDANLRCSIPEDVLTDELTGELRSRKSEIITFLRQAKSST
CCHHHHHHHHHHHCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NYTQAITPAPRNGNLPLSFAQQRLWFLEQLQPDSYTYNLPTAVRLTGILDVGLLERSLNT
CCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCEEEEHHHHHHHHHHHHHH
IIQRHELLRTNFKTVDGNPVLDIQPSVTLPLAVIDLQAFNLLEQDEEVRHLALKEAQTPF
HHHHHHHHHCCCEECCCCEEEEECCCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHCCCCH
DLATDVLLRVKILQLAKDENVVLFTMHHIVSDGWSMEILVKELATLYTAFSGNQPSPLPE
HHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
LAIQYVDFAIWQRQWLQGEVLETQLDYWRQQLGGILPVLQLPTDYPRGRVQTFRGAIESF
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHC
SLSPQLSQGIIKLAKNAGVTPFVTLLTAYKILLHRYTGQTDILVGTPVANRHRREIEALI
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHH
GFFVNTLVLRTNLADNPSFQELLQQLINTTWQAYDHQDIPFEKLVEVLQPERDLSFNPLF
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCEE
QVKFRLENAPTEKLELPGLTLRPLNRTEASAKLDLSLDMYETSEGFVGAFEYNRDLFAPE
EEEEEECCCCCCCEECCCCEECCCCCCCCCEEEEEEEEEEECCCCCEEEEECCCCCCCHH
TINRMVGHFQTVLTAIVENPQKRISELPLLTDKEKQTILIDWNQTQVECPSHLTFQDLFA
HHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEEEECCCCEECCCCCCCHHHHHH
AQVEKTPDEVAIIFENQSLTYTELNQKSNQVAHYLKKKGVKPEVIVGLCVERSPLMIIAL
HHHHCCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHH
LGILKAGGAYLPLDPNYPPERLGYMLADSQVPILLTETSLKVATSSSYEIIYLDTDWETI
HHHHHCCCEEECCCCCCCHHHHCEEEECCCCCEEEEECCEEEEECCCEEEEEEECCHHHH
SQCSIENPESEVKPENLAYLIYTSGSTGKPKGVLIPHIGLTNLTQHKIQVCDVHPGDCVL
HHCCCCCCHHHCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCEEEEEECCCHHHHH
QFFSLSFDASIPEIIMALGSGAKLCLAKSESLLPGETLLKLLRDNAVTHITITPSALSLL
HHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECHHHHHHC
PSADLPHLRMVLVGGEAPSPELIAKWSQGRRFINAYGPTEVTVNASMVLCGNGHPLVPTI
CCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEEEECCCEEEEEEEEEEEECCCCCCCCEE
RPSANKQLYILDNYLQPVPIGVIGELYIGGIGLARGYLNRPDLTAERFIRDWGLGTGDWG
CCCCCCEEEEEECCCCCCCCCHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHCCCCCCCCC
LGKEVSLVNSQQSTVNSDSRLYKTGDLAYYLPDGRIRLLGRVDNQVKIRGFRIEPQEVET
CCCEEEEECCCHHHCCCCCCEEEECCEEEECCCCCEEEEEECCCEEEEEEEECCHHHHHH
LLCQHPGVRAGVVIVREDQPGEKRLVAYVIPNEEGGEQKFPQSPIPNPQSPIPNPQSLRA
HHHCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
FMREKLPEYLVPSAFVLLTDLPLTPNGKVDTHALPAPEQVLANAEFIAPRTDIEAQLADI
HHHHHCHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCEECCCCCHHHHHHHH
YAQILKLEKVSIQDDFFELGGHSLIATQLIAQALQVFQVELTVMDLFDAPTVAGLAERIL
HHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEEHHCCCHHHHHHHHHH
QRQLKAEIPVISDTSDDEREEFEI
HHHHHHCCCEECCCCCCCHHHCCC
>Mature Secondary Structure
MKTIEKFLAHLYSLDVKLWVEDANLRCSIPEDVLTDELTGELRSRKSEIITFLRQAKSST
CCHHHHHHHHHHHCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NYTQAITPAPRNGNLPLSFAQQRLWFLEQLQPDSYTYNLPTAVRLTGILDVGLLERSLNT
CCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCEEEEHHHHHHHHHHHHHH
IIQRHELLRTNFKTVDGNPVLDIQPSVTLPLAVIDLQAFNLLEQDEEVRHLALKEAQTPF
HHHHHHHHHCCCEECCCCEEEEECCCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHCCCCH
DLATDVLLRVKILQLAKDENVVLFTMHHIVSDGWSMEILVKELATLYTAFSGNQPSPLPE
HHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
LAIQYVDFAIWQRQWLQGEVLETQLDYWRQQLGGILPVLQLPTDYPRGRVQTFRGAIESF
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHC
SLSPQLSQGIIKLAKNAGVTPFVTLLTAYKILLHRYTGQTDILVGTPVANRHRREIEALI
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHH
GFFVNTLVLRTNLADNPSFQELLQQLINTTWQAYDHQDIPFEKLVEVLQPERDLSFNPLF
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCEE
QVKFRLENAPTEKLELPGLTLRPLNRTEASAKLDLSLDMYETSEGFVGAFEYNRDLFAPE
EEEEEECCCCCCCEECCCCEECCCCCCCCCEEEEEEEEEEECCCCCEEEEECCCCCCCHH
TINRMVGHFQTVLTAIVENPQKRISELPLLTDKEKQTILIDWNQTQVECPSHLTFQDLFA
HHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEEEECCCCEECCCCCCCHHHHHH
AQVEKTPDEVAIIFENQSLTYTELNQKSNQVAHYLKKKGVKPEVIVGLCVERSPLMIIAL
HHHHCCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHH
LGILKAGGAYLPLDPNYPPERLGYMLADSQVPILLTETSLKVATSSSYEIIYLDTDWETI
HHHHHCCCEEECCCCCCCHHHHCEEEECCCCCEEEEECCEEEEECCCEEEEEEECCHHHH
SQCSIENPESEVKPENLAYLIYTSGSTGKPKGVLIPHIGLTNLTQHKIQVCDVHPGDCVL
HHCCCCCCHHHCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCEEEEEECCCHHHHH
QFFSLSFDASIPEIIMALGSGAKLCLAKSESLLPGETLLKLLRDNAVTHITITPSALSLL
HHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECHHHHHHC
PSADLPHLRMVLVGGEAPSPELIAKWSQGRRFINAYGPTEVTVNASMVLCGNGHPLVPTI
CCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEEEECCCEEEEEEEEEEEECCCCCCCCEE
RPSANKQLYILDNYLQPVPIGVIGELYIGGIGLARGYLNRPDLTAERFIRDWGLGTGDWG
CCCCCCEEEEEECCCCCCCCCHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHCCCCCCCCC
LGKEVSLVNSQQSTVNSDSRLYKTGDLAYYLPDGRIRLLGRVDNQVKIRGFRIEPQEVET
CCCEEEEECCCHHHCCCCCCEEEECCEEEECCCCCEEEEEECCCEEEEEEEECCHHHHHH
LLCQHPGVRAGVVIVREDQPGEKRLVAYVIPNEEGGEQKFPQSPIPNPQSPIPNPQSLRA
HHHCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
FMREKLPEYLVPSAFVLLTDLPLTPNGKVDTHALPAPEQVLANAEFIAPRTDIEAQLADI
HHHHHCHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCEECCCCCHHHHHHHH
YAQILKLEKVSIQDDFFELGGHSLIATQLIAQALQVFQVELTVMDLFDAPTVAGLAERIL
HHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEEHHCCCHHHHHHHHHH
QRQLKAEIPVISDTSDDEREEFEI
HHHHHHCCCEECCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA