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The map label for this gene is pilC [H]

Identifier: 17229934

GI number: 17229934

Start: 2934849

End: 2936072

Strand: Reverse

Name: pilC [H]

Synonym: all2442

Alternate gene names: 17229934

Gene position: 2936072-2934849 (Counterclockwise)

Preceding gene: 17229935

Following gene: 17229933

Centisome position: 45.78

GC content: 40.2

Gene sequence:

>1224_bases
ATGCCAACATTTATTGCCCAAGTTCGGGACACGCAAGGAAAAACGAGAAAAGAGAAAGTTGTTGCTGAATCTTTGGCACA
AGCTCGTACTAATCTTAGAGATCAGGGATTGGTCATCCAAGAACTTAAACAGTCGCAAAACTTTGCTGCCAATTTTGATT
TCCAAAAGTTTCAGAATTCCTTCGTCAAGGTAACAGTAAAGGAAAAGGCAGTATTCTCTCGACAACTTGCCACATTGGTA
AATGCTGGTGTAGCAATTGTCCGAGGGTTGGGAGTGCTAGGCGATCAGTGTACCAATGCTAAACTCAAACAAGCCCTCAA
TGATATTAGCAATGATGTTCAAAGTGGGGTCAATCTTTCGGATGCTATGCGTAAGCATCCTGGCTGTTTTGATGGTTTGT
ATGTGAGCATGATTCAAGCCGGGGAAGTCGGTGGTGTTTTAGATGAAGTTTTGAATCGTTTAGCCAAATTGTTAGAAGAC
ATGGCTCGATTACAAAACCAAATTAAGTCAGCCCTAGCTTATCCTGTGGTGGTTGGTATTCTAGCAACTGGTATTTTTGT
GGGGATGACTGTTTTTCTTATCCCCATTTTTGCCAAGATTTTCGTGGAATTAGGAACAGAATTACCTCCATTAACCGCAT
TTTTAATGACTTGTAGCCAAGTTTTAAGAAGTTTGTGGTCGTTAGTGATTATTGCTGGAATTGTTGGCTTCAAATTTGCC
TATTCACAGTATTATAAAACTCGTATTGGGAGGGAAACAATTGACCGCCTTTCTTTAAAGATGCCTTTATTTGGTGACTT
GATTCAAAAATCTTCAGTAGCCCGTTTTAGTCGTACTTTTGGTTCTTTGACTCGTTCTGGTGTACCTATTCTTACTTCTT
TAGAGATCGTGCGAGATACATCAGGAAATCAGGTTGTTGCTAATGCTATTGATGCCGCACGAGCCGAAATTCAGCAAGGA
GGTATGATTAGTATCGCTCTCCAAAAAGAAGCGGTTTTTCCACCAATGGCAATTCAAATGATTAGCATCGGTGAAGAAAC
CGGGGAATTGGATGGAATGCTGATGAAAATTGCCGATTTTTATGAAGATGAGGTTGAGCAAGCCGTCAAAGCATTAACCA
GCGTTTTAGAACCAATTATGATTTTAGTTCTAGGGGGTATGGTGGGAACAATTCTATTAGCGATGTATTTACCCTTATTC
AAAGTATTTGAAACACTGGGATAG

Upstream 100 bases:

>100_bases
TCAATAGTTATTGTTTATTAGCCATGAATAATAACTATTAATTATTTTTGAATTTTGTAGCTTGCTTCTCGTAGAGTATT
TTGAATTTTGATATTGATAT

Downstream 100 bases:

>100_bases
ATGAGATATGAGGAAAATTAATTTTTTGAATTTTGAATGGATTATGAAAAAAAGTGAGTTTTAAAACCGAGTGGAACTGT
GGGGGAAAGAATCATTGTTT

Product: pilin biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MPTFIAQVRDTQGKTRKEKVVAESLAQARTNLRDQGLVIQELKQSQNFAANFDFQKFQNSFVKVTVKEKAVFSRQLATLV
NAGVAIVRGLGVLGDQCTNAKLKQALNDISNDVQSGVNLSDAMRKHPGCFDGLYVSMIQAGEVGGVLDEVLNRLAKLLED
MARLQNQIKSALAYPVVVGILATGIFVGMTVFLIPIFAKIFVELGTELPPLTAFLMTCSQVLRSLWSLVIIAGIVGFKFA
YSQYYKTRIGRETIDRLSLKMPLFGDLIQKSSVARFSRTFGSLTRSGVPILTSLEIVRDTSGNQVVANAIDAARAEIQQG
GMISIALQKEAVFPPMAIQMISIGEETGELDGMLMKIADFYEDEVEQAVKALTSVLEPIMILVLGGMVGTILLAMYLPLF
KVFETLG

Sequences:

>Translated_407_residues
MPTFIAQVRDTQGKTRKEKVVAESLAQARTNLRDQGLVIQELKQSQNFAANFDFQKFQNSFVKVTVKEKAVFSRQLATLV
NAGVAIVRGLGVLGDQCTNAKLKQALNDISNDVQSGVNLSDAMRKHPGCFDGLYVSMIQAGEVGGVLDEVLNRLAKLLED
MARLQNQIKSALAYPVVVGILATGIFVGMTVFLIPIFAKIFVELGTELPPLTAFLMTCSQVLRSLWSLVIIAGIVGFKFA
YSQYYKTRIGRETIDRLSLKMPLFGDLIQKSSVARFSRTFGSLTRSGVPILTSLEIVRDTSGNQVVANAIDAARAEIQQG
GMISIALQKEAVFPPMAIQMISIGEETGELDGMLMKIADFYEDEVEQAVKALTSVLEPIMILVLGGMVGTILLAMYLPLF
KVFETLG
>Mature_406_residues
PTFIAQVRDTQGKTRKEKVVAESLAQARTNLRDQGLVIQELKQSQNFAANFDFQKFQNSFVKVTVKEKAVFSRQLATLVN
AGVAIVRGLGVLGDQCTNAKLKQALNDISNDVQSGVNLSDAMRKHPGCFDGLYVSMIQAGEVGGVLDEVLNRLAKLLEDM
ARLQNQIKSALAYPVVVGILATGIFVGMTVFLIPIFAKIFVELGTELPPLTAFLMTCSQVLRSLWSLVIIAGIVGFKFAY
SQYYKTRIGRETIDRLSLKMPLFGDLIQKSSVARFSRTFGSLTRSGVPILTSLEIVRDTSGNQVVANAIDAARAEIQQGG
MISIALQKEAVFPPMAIQMISIGEETGELDGMLMKIADFYEDEVEQAVKALTSVLEPIMILVLGGMVGTILLAMYLPLFK
VFETLG

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=380, Percent_Identity=28.6842105263158, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786295, Length=331, Percent_Identity=30.2114803625378, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44429; Mature: 44298

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PTFIAQVRDTQGKTRKEKVVAESLAQARTNLRDQGLVIQELKQSQNFAANFDFQKFQNS
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHCCC
FVKVTVKEKAVFSRQLATLVNAGVAIVRGLGVLGDQCTNAKLKQALNDISNDVQSGVNLS
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHH
DAMRKHPGCFDGLYVSMIQAGEVGGVLDEVLNRLAKLLEDMARLQNQIKSALAYPVVVGI
HHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATGIFVGMTVFLIPIFAKIFVELGTELPPLTAFLMTCSQVLRSLWSLVIIAGIVGFKFA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YSQYYKTRIGRETIDRLSLKMPLFGDLIQKSSVARFSRTFGSLTRSGVPILTSLEIVRDT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
SGNQVVANAIDAARAEIQQGGMISIALQKEAVFPPMAIQMISIGEETGELDGMLMKIADF
CCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
YEDEVEQAVKALTSVLEPIMILVLGGMVGTILLAMYLPLFKVFETLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]