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The map label for this gene is dapL [H]

Identifier: 17229832

GI number: 17229832

Start: 2822818

End: 2824032

Strand: Reverse

Name: dapL [H]

Synonym: all2340

Alternate gene names: 17229832

Gene position: 2824032-2822818 (Counterclockwise)

Preceding gene: 17229833

Following gene: 17229829

Centisome position: 44.03

GC content: 43.95

Gene sequence:

>1215_bases
ATGCAATTCTCACAGCGTTTACACCCTCTGCAATCTAATGTCTTTGCTGATATGGATAAGGCTAAGTCCTTGGCTTTAGC
AGCAGGGAAAGAGTTAATTGATTTGTCTCTAGGATCTTCAGATTTGCCAGCCGAAGCTCATGTGATTGAAGCGATCGCTA
AATCTTTATATGATCCCAGTACCCACGGCTACTTGCTTTTTAATGGGACAAGGGATTTTCGTCAAGCCGCAGCTAACTGG
TATGAACAAAAATTTGGGGTGAAAGTCGATCCCGAAACTGAAGTACTGCCTTTAATTGGTTCCCAGGAAGGTACTGCTCA
TTTACCTTTGGCATTGCTCAATCCTGGGGATTTTGCTTTACTACTTGATCCCGGCTACCCTTCCCATGCTGGGGGAGTTT
ACTTAGCTAGTGGGCAAATTTACCCAATGCCATTAAAGGCAGAAAATGATTTCTTACCTGTGTTTGCTGATATCCCGACG
GATGTCTTGGCTCAGTCGCGGATGATGGTATTAAGCTATCCTCACAATCCCACAGCAGCGATCGCACCTTTATCTTTCTT
TAAGGAAGCCGTGGCTTTTTGTCAGGAACATAACATTGCATTGGTGCATGATTTTCCCTATGTGGATATGGTGTTTGAGA
ATGCTGGGAACTTGAATACAAATCTTCCCCAATCCCCAATCCCTAATCACCAATCCCTAGTCCCTTCAATTCTCCAAGCT
GACCCAGATAAAAGCGTTTCTATTGAATTTTTCACTCTTTCTAAGTCTTATAATATGGGCGGCTTTCGCATTGGCTATGC
TATCGGTAATGCCCAGATGATTCAGGCTTTACGGCAAATCAAAGCAGCCGTTGATTTTAACCAGTATCGGGGAATTTTAA
ATGGAGCGATCGCTGCTCTGACTGGCCCGCAAGCAGGCGTAGAAGCTGCTGTGTCAACATTTTGCCAACGTCGTGATGCC
TTTATTAATGCTCTACACCACATTGGTTGGTATGTTCCCACTCCCAAAGCCACTATGTATATCTGGGCAAAATTACCGTC
TTCTTGGAGTCAAAATTCCATAGAATTTTGTACACAGTTAGTCAGACAAACTGGTGTAGCGGCTTCCCCTGGTGCTGGCT
TCGGCAAATCTGGTGAAGGATATGTGCGCTTTGCCCTAGTCCATGAACCATCTATATTAAAAATTGCCGTTGAACGAATG
AGTAATTTTCTCTAA

Upstream 100 bases:

>100_bases
ATAATAATTAGTCAGTAGTCAGTGGTTAGTAGTCAGTCGTGAAAAACAAACAACAACTGACAACTGACAACTGACAACTG
ACAACTGACCAAGGACTAAT

Downstream 100 bases:

>100_bases
TCTAGCCTAACCAATACTTATTACTTAAACTAAGATTTTGACACAAGGGACATCCGCACGCGATAGGCTGCTTTTAACTT
CCCCGAAACGACTCTTGTCG

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MQFSQRLHPLQSNVFADMDKAKSLALAAGKELIDLSLGSSDLPAEAHVIEAIAKSLYDPSTHGYLLFNGTRDFRQAAANW
YEQKFGVKVDPETEVLPLIGSQEGTAHLPLALLNPGDFALLLDPGYPSHAGGVYLASGQIYPMPLKAENDFLPVFADIPT
DVLAQSRMMVLSYPHNPTAAIAPLSFFKEAVAFCQEHNIALVHDFPYVDMVFENAGNLNTNLPQSPIPNHQSLVPSILQA
DPDKSVSIEFFTLSKSYNMGGFRIGYAIGNAQMIQALRQIKAAVDFNQYRGILNGAIAALTGPQAGVEAAVSTFCQRRDA
FINALHHIGWYVPTPKATMYIWAKLPSSWSQNSIEFCTQLVRQTGVAASPGAGFGKSGEGYVRFALVHEPSILKIAVERM
SNFL

Sequences:

>Translated_404_residues
MQFSQRLHPLQSNVFADMDKAKSLALAAGKELIDLSLGSSDLPAEAHVIEAIAKSLYDPSTHGYLLFNGTRDFRQAAANW
YEQKFGVKVDPETEVLPLIGSQEGTAHLPLALLNPGDFALLLDPGYPSHAGGVYLASGQIYPMPLKAENDFLPVFADIPT
DVLAQSRMMVLSYPHNPTAAIAPLSFFKEAVAFCQEHNIALVHDFPYVDMVFENAGNLNTNLPQSPIPNHQSLVPSILQA
DPDKSVSIEFFTLSKSYNMGGFRIGYAIGNAQMIQALRQIKAAVDFNQYRGILNGAIAALTGPQAGVEAAVSTFCQRRDA
FINALHHIGWYVPTPKATMYIWAKLPSSWSQNSIEFCTQLVRQTGVAASPGAGFGKSGEGYVRFALVHEPSILKIAVERM
SNFL
>Mature_404_residues
MQFSQRLHPLQSNVFADMDKAKSLALAAGKELIDLSLGSSDLPAEAHVIEAIAKSLYDPSTHGYLLFNGTRDFRQAAANW
YEQKFGVKVDPETEVLPLIGSQEGTAHLPLALLNPGDFALLLDPGYPSHAGGVYLASGQIYPMPLKAENDFLPVFADIPT
DVLAQSRMMVLSYPHNPTAAIAPLSFFKEAVAFCQEHNIALVHDFPYVDMVFENAGNLNTNLPQSPIPNHQSLVPSILQA
DPDKSVSIEFFTLSKSYNMGGFRIGYAIGNAQMIQALRQIKAAVDFNQYRGILNGAIAALTGPQAGVEAAVSTFCQRRDA
FINALHHIGWYVPTPKATMYIWAKLPSSWSQNSIEFCTQLVRQTGVAASPGAGFGKSGEGYVRFALVHEPSILKIAVERM
SNFL

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=425, Percent_Identity=19.2941176470588, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI56713254, Length=425, Percent_Identity=19.2941176470588, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1788722, Length=394, Percent_Identity=36.5482233502538, Blast_Score=281, Evalue=4e-77,
Organism=Escherichia coli, GI1786816, Length=400, Percent_Identity=22, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1788627, Length=259, Percent_Identity=26.2548262548263, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71994472, Length=265, Percent_Identity=24.1509433962264, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71994476, Length=265, Percent_Identity=24.1509433962264, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=404, Percent_Identity=19.0594059405941, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28573069, Length=412, Percent_Identity=19.6601941747573, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646114, Length=412, Percent_Identity=19.6601941747573, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573067, Length=412, Percent_Identity=19.6601941747573, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573065, Length=412, Percent_Identity=19.6601941747573, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44000; Mature: 44000

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFSQRLHPLQSNVFADMDKAKSLALAAGKELIDLSLGSSDLPAEAHVIEAIAKSLYDPS
CCHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCC
THGYLLFNGTRDFRQAAANWYEQKFGVKVDPETEVLPLIGSQEGTAHLPLALLNPGDFAL
CCCEEEECCCHHHHHHHHHHHHHHCCCEECCCCCEEEEECCCCCCCCCCEEEECCCCEEE
LLDPGYPSHAGGVYLASGQIYPMPLKAENDFLPVFADIPTDVLAQSRMMVLSYPHNPTAA
EECCCCCCCCCCEEEECCEEEECCCCCCCCCEEEEECCCHHHHHCCCEEEEECCCCCCHH
IAPLSFFKEAVAFCQEHNIALVHDFPYVDMVFENAGNLNTNLPQSPIPNHQSLVPSILQA
HHHHHHHHHHHHHHHHCCEEEEECCCCEEHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHC
DPDKSVSIEFFTLSKSYNMGGFRIGYAIGNAQMIQALRQIKAAVDFNQYRGILNGAIAAL
CCCCCEEEEEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHHHCHHHHHHHHHHHHHEE
TGPQAGVEAAVSTFCQRRDAFINALHHIGWYVPTPKATMYIWAKLPSSWSQNSIEFCTQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHH
VRQTGVAASPGAGFGKSGEGYVRFALVHEPSILKIAVERMSNFL
HHHCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MQFSQRLHPLQSNVFADMDKAKSLALAAGKELIDLSLGSSDLPAEAHVIEAIAKSLYDPS
CCHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCC
THGYLLFNGTRDFRQAAANWYEQKFGVKVDPETEVLPLIGSQEGTAHLPLALLNPGDFAL
CCCEEEECCCHHHHHHHHHHHHHHCCCEECCCCCEEEEECCCCCCCCCCEEEECCCCEEE
LLDPGYPSHAGGVYLASGQIYPMPLKAENDFLPVFADIPTDVLAQSRMMVLSYPHNPTAA
EECCCCCCCCCCEEEECCEEEECCCCCCCCCEEEEECCCHHHHHCCCEEEEECCCCCCHH
IAPLSFFKEAVAFCQEHNIALVHDFPYVDMVFENAGNLNTNLPQSPIPNHQSLVPSILQA
HHHHHHHHHHHHHHHHCCEEEEECCCCEEHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHC
DPDKSVSIEFFTLSKSYNMGGFRIGYAIGNAQMIQALRQIKAAVDFNQYRGILNGAIAAL
CCCCCEEEEEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHHHCHHHHHHHHHHHHHEE
TGPQAGVEAAVSTFCQRRDAFINALHHIGWYVPTPKATMYIWAKLPSSWSQNSIEFCTQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHH
VRQTGVAASPGAGFGKSGEGYVRFALVHEPSILKIAVERMSNFL
HHHCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA