Click here to switch to the map view.

The map label for this gene is iolS [H]

Identifier: 17229808

GI number: 17229808

Start: 2790870

End: 2791724

Strand: Reverse

Name: iolS [H]

Synonym: all2316

Alternate gene names: 17229808

Gene position: 2791724-2790870 (Counterclockwise)

Preceding gene: 17229809

Following gene: 17229807

Centisome position: 43.53

GC content: 44.09

Gene sequence:

>855_bases
ATGGAAACTACACAGCTAGGAAAAACAGGTGTATTTGTCAGCGCCATTGGTTTGGGTGGAATGCCAATGTCGATATATAA
TCGACCACCAGAATCAGATTCAATTCAAGTTATCCACCGTGCTTTAGATTTAGGGATTACATTTATTGACACTGCCGATT
CTTATTGTAAGGATGAGTCAGACAAGCACCACAATGAAAGACTCATCCACAAAGCACTTAGCACTTATGCGGGTGATACT
AGCCAAGTGGTTGTGGCGACGAAAGGCGGCTTAATGCGTCCTAATGAAAGTTGGACACGCAACGGGAATCCAGAACATCT
GCGTCAAACTATCCGCGTTAGTTTTGAGGCGTTGGGTGGTGAAAAACCGATTGATGTTTGGCAATACCACTCTCCAGACC
CAGAATATACAATTGCAGAATCCTTGACACCTGTGAAAGAAGCTGTGGAAGCAGGTTTGATTCGATTTGTGGGAGTTTCT
AATTTTTCTGTGGAACAAATTAAGCAAGCACGGGATGTGGTGGATATTGTCTCAGTGCAGAATCAATACAGTCCTTGGGA
AAGACAGCCAGAAAAAGACGGTGTTTTGCAGTATTGTGAACAAGAAAAACTAACTTTTTTACCTTGGAGTCCCTTTGGAG
GTCGTCGTCGCCATCAAGATTTACAGGATATTCCCGCGATCGCCCAATTAGCCAAAGCCAAAGGTGTATCTGTATACTCG
ATAGTATTGGCCTGGTTACGCGCCAAATCCCCGGCAATTTTGCCCATCCCCGGCGCAAGCAAAATTTCCAGCATCGAAGA
TTCAGTCAGTGCTGTAAATGTCCAACTAAGTGACGAAGAAGTCCAGAAAATTTAG

Upstream 100 bases:

>100_bases
GAGTTTCAATTTTAACATCACCTTACCTTAGAGGAATTGTCAAAACCTCCTTGACCCGCTATTAGATAGTTAGTGATGCT
ATCAAAATCAAGCGAAAAGC

Downstream 100 bases:

>100_bases
TAAATAGCTTTGTTGACTGTTAACAGTTAACTGTTAACTCATGACTACTTGTACCCGTGGTAACACAATTTGGGGTAAAA
TCAAAGACTTGCCAATAAAT

Product: aldo/keto reductase

Products: NA

Alternate protein names: AKR11A; Vegetative protein 147; VEG147 [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
METTQLGKTGVFVSAIGLGGMPMSIYNRPPESDSIQVIHRALDLGITFIDTADSYCKDESDKHHNERLIHKALSTYAGDT
SQVVVATKGGLMRPNESWTRNGNPEHLRQTIRVSFEALGGEKPIDVWQYHSPDPEYTIAESLTPVKEAVEAGLIRFVGVS
NFSVEQIKQARDVVDIVSVQNQYSPWERQPEKDGVLQYCEQEKLTFLPWSPFGGRRRHQDLQDIPAIAQLAKAKGVSVYS
IVLAWLRAKSPAILPIPGASKISSIEDSVSAVNVQLSDEEVQKI

Sequences:

>Translated_284_residues
METTQLGKTGVFVSAIGLGGMPMSIYNRPPESDSIQVIHRALDLGITFIDTADSYCKDESDKHHNERLIHKALSTYAGDT
SQVVVATKGGLMRPNESWTRNGNPEHLRQTIRVSFEALGGEKPIDVWQYHSPDPEYTIAESLTPVKEAVEAGLIRFVGVS
NFSVEQIKQARDVVDIVSVQNQYSPWERQPEKDGVLQYCEQEKLTFLPWSPFGGRRRHQDLQDIPAIAQLAKAKGVSVYS
IVLAWLRAKSPAILPIPGASKISSIEDSVSAVNVQLSDEEVQKI
>Mature_284_residues
METTQLGKTGVFVSAIGLGGMPMSIYNRPPESDSIQVIHRALDLGITFIDTADSYCKDESDKHHNERLIHKALSTYAGDT
SQVVVATKGGLMRPNESWTRNGNPEHLRQTIRVSFEALGGEKPIDVWQYHSPDPEYTIAESLTPVKEAVEAGLIRFVGVS
NFSVEQIKQARDVVDIVSVQNQYSPWERQPEKDGVLQYCEQEKLTFLPWSPFGGRRRHQDLQDIPAIAQLAKAKGVSVYS
IVLAWLRAKSPAILPIPGASKISSIEDSVSAVNVQLSDEEVQKI

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787674, Length=284, Percent_Identity=28.5211267605634, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI87081735, Length=327, Percent_Identity=28.4403669724771, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789375, Length=321, Percent_Identity=21.4953271028037, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI48994888, Length=260, Percent_Identity=25.3846153846154, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786400, Length=277, Percent_Identity=23.4657039711191, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17561298, Length=302, Percent_Identity=24.8344370860927, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24646159, Length=176, Percent_Identity=28.4090909090909, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31453; Mature: 31453

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METTQLGKTGVFVSAIGLGGMPMSIYNRPPESDSIQVIHRALDLGITFIDTADSYCKDES
CCCCCCCCCCEEEEEECCCCCCHHHCCCCCCCCHHHHHHHHHHHCEEEEECCHHHHCCCC
DKHHNERLIHKALSTYAGDTSQVVVATKGGLMRPNESWTRNGNPEHLRQTIRVSFEALGG
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
EKPIDVWQYHSPDPEYTIAESLTPVKEAVEAGLIRFVGVSNFSVEQIKQARDVVDIVSVQ
CCCCCEEECCCCCCCEEHHHHCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHH
NQYSPWERQPEKDGVLQYCEQEKLTFLPWSPFGGRRRHQDLQDIPAIAQLAKAKGVSVYS
CCCCCCCCCCCCCHHHHHHCCCCCEEECCCCCCCCHHHCHHHHHHHHHHHHHHCCCHHHH
IVLAWLRAKSPAILPIPGASKISSIEDSVSAVNVQLSDEEVQKI
HHHHHHHCCCCCEEECCCCHHHHHHHHHHHEEEEEECHHHHHCC
>Mature Secondary Structure
METTQLGKTGVFVSAIGLGGMPMSIYNRPPESDSIQVIHRALDLGITFIDTADSYCKDES
CCCCCCCCCCEEEEEECCCCCCHHHCCCCCCCCHHHHHHHHHHHCEEEEECCHHHHCCCC
DKHHNERLIHKALSTYAGDTSQVVVATKGGLMRPNESWTRNGNPEHLRQTIRVSFEALGG
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
EKPIDVWQYHSPDPEYTIAESLTPVKEAVEAGLIRFVGVSNFSVEQIKQARDVVDIVSVQ
CCCCCEEECCCCCCCEEHHHHCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHH
NQYSPWERQPEKDGVLQYCEQEKLTFLPWSPFGGRRRHQDLQDIPAIAQLAKAKGVSVYS
CCCCCCCCCCCCCHHHHHHCCCCCEEECCCCCCCCHHHCHHHHHHHHHHHHHHCCCHHHH
IVLAWLRAKSPAILPIPGASKISSIEDSVSAVNVQLSDEEVQKI
HHHHHHHCCCCCEEECCCCHHHHHHHHHHHEEEEEECHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 9298659 [H]