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The map label for this gene is ruvC [H]

Identifier: 17229789

GI number: 17229789

Start: 2767670

End: 2768161

Strand: Reverse

Name: ruvC [H]

Synonym: all2297

Alternate gene names: 17229789

Gene position: 2768161-2767670 (Counterclockwise)

Preceding gene: 17229791

Following gene: 17229785

Centisome position: 43.16

GC content: 42.48

Gene sequence:

>492_bases
ATGGAAAAGCGAATTTTAGGATTAGACCCAGGACTGGCAATTTTAGGATTTGGGGCAATTACTTGTACACCAGGCTTAAC
CCAACTACAAAGTACAAAAGTCAATGTCTTGGACTTTGGAGTCATCAAAACCTCAGCAGATATAGAGATTGGGCAACGCT
TGTGTACTTTGTTCGATGATTTGCACACCGTGATTGATCAATTACAACCTGATGTAGTCGCAATTGAAAAACTGTTCTTC
TATCGTATGTCAAGTACAATTGTTGTGGCACAAGCTAGAGGTGTAGTGATGTTAGCCTTAGCACAGCACCATTTGCCTTA
TGTCGAATTTACACCAGCACAGATTAAGCTAGCTTTAACGGGATATGGCAACGCTGATAAATCTGAAGTGCAAGAGGCGG
TAGCACGAGAGTTGGATTTAGCAGAAATTCCTCGGCCAGATGATGCTGCTGATGCCTTGGCTGTAGCTTTGACAGCTTGG
TATCAAATGTGA

Upstream 100 bases:

>100_bases
TGAAATTATGAAACCTTTTTTTAGTTCCACTTAAACTAAAAGCAAGTCATCAAGGCTGCCAGTATGTCCATCAAACCATA
ACTTGGTAAAAGATAATTTA

Downstream 100 bases:

>100_bases
TTTTTTCCCAAACTCAGCCAGAATTTAGATTATTCTTGACAACCGATACCCATTACCAATAGTCCAGGCCAATATAAATA
TACTAGTATTTCCAAATTTT

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MEKRILGLDPGLAILGFGAITCTPGLTQLQSTKVNVLDFGVIKTSADIEIGQRLCTLFDDLHTVIDQLQPDVVAIEKLFF
YRMSSTIVVAQARGVVMLALAQHHLPYVEFTPAQIKLALTGYGNADKSEVQEAVARELDLAEIPRPDDAADALAVALTAW
YQM

Sequences:

>Translated_163_residues
MEKRILGLDPGLAILGFGAITCTPGLTQLQSTKVNVLDFGVIKTSADIEIGQRLCTLFDDLHTVIDQLQPDVVAIEKLFF
YRMSSTIVVAQARGVVMLALAQHHLPYVEFTPAQIKLALTGYGNADKSEVQEAVARELDLAEIPRPDDAADALAVALTAW
YQM
>Mature_163_residues
MEKRILGLDPGLAILGFGAITCTPGLTQLQSTKVNVLDFGVIKTSADIEIGQRLCTLFDDLHTVIDQLQPDVVAIEKLFF
YRMSSTIVVAQARGVVMLALAQHHLPYVEFTPAQIKLALTGYGNADKSEVQEAVARELDLAEIPRPDDAADALAVALTAW
YQM

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=142, Percent_Identity=33.8028169014084, Blast_Score=79, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 17741; Mature: 17741

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRILGLDPGLAILGFGAITCTPGLTQLQSTKVNVLDFGVIKTSADIEIGQRLCTLFDD
CCCCEECCCCCHHHHCCCCEECCCCCHHHHCCEEEEEEEEEEECCCCHHHHHHHHHHHHH
LHTVIDQLQPDVVAIEKLFFYRMSSTIVVAQARGVVMLALAQHHLPYVEFTPAQIKLALT
HHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCEEEEEEHHHCCCCEEECCCEEEEEEE
GYGNADKSEVQEAVARELDLAEIPRPDDAADALAVALTAWYQM
CCCCCCHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKRILGLDPGLAILGFGAITCTPGLTQLQSTKVNVLDFGVIKTSADIEIGQRLCTLFDD
CCCCEECCCCCHHHHCCCCEECCCCCHHHHCCEEEEEEEEEEECCCCHHHHHHHHHHHHH
LHTVIDQLQPDVVAIEKLFFYRMSSTIVVAQARGVVMLALAQHHLPYVEFTPAQIKLALT
HHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCEEEEEEHHHCCCCEEECCCEEEEEEE
GYGNADKSEVQEAVARELDLAEIPRPDDAADALAVALTAWYQM
CCCCCCHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA