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The map label for this gene is zraR [H]

Identifier: 17229773

GI number: 17229773

Start: 2747530

End: 2748228

Strand: Reverse

Name: zraR [H]

Synonym: all2281

Alternate gene names: 17229773

Gene position: 2748228-2747530 (Counterclockwise)

Preceding gene: 17229774

Following gene: 17229769

Centisome position: 42.85

GC content: 32.05

Gene sequence:

>699_bases
ATGACTGAGTATATATTATTTGTTGACGACGAACCATTAATAAAACGTTTAGTAACTCATTATTTTCGGCATAAGATACG
TCAAGGAGAATATGAATTTATCTTTGCTCATAATGGTAGAGATGCCTTGGAAAAATTACAAGCAAATCCGCAAATAGATT
TATTAGTAACTGATATTAATATGCCGGAGATAGATGGGCTAACTTTACTTAGTAAAATACGGGATCTGAATTTAGATATT
AAAGCTGTCATTGTATCTGCTTACGAGGATCTCAAAAACATTAGACGAGCCATGAATCAAGGTGCTTTTGATTTTATTAC
TAAGCCTATAGATTTTCAAGAATTAGAAAGCACTATGAACCGTGCTTTAGAGTATGTGCAAGAGATAAAAAATAAAAGTT
CTTTAGTGTCATCTGATCAATTACCAGAAGTTCAAAGTAAGGAAATATATGTAAATAATCAATTGGTTTTGGAAAAACAG
CAGGAAATCAACCATTCAACCAACTTAGATTATATCGATTTTCAGGAAATAGAGACTGGTGTTAATCAACTAATTAATCA
TTTACGACTTTATCAGCAAGACTTTCCTCTTGCCTCACCACAAATTTTGCAGAACGCCAAAGATATTGATTTGGCATCTC
TATTGCTAGGATTACCTACAACTATACAATCAATGAAAGATAAAACTAATCAACCATGA

Upstream 100 bases:

>100_bases
CAGGGAGATATTAAGATTAACACTGAAGTTGGAGAATATACGGAATTCGTTCTTACAATACCAATTAATTTATCCTTTCC
TGAATATCAGGGTTGCAAAT

Downstream 100 bases:

>100_bases
ACAAAGCATGATGAAAATTACAATAAATCTGCTGATTTTCAGCTAAATTATTAATTTGATTACATCCAAAAATTTGAGTT
ACTTAAGAACAAAATTTATT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTEYILFVDDEPLIKRLVTHYFRHKIRQGEYEFIFAHNGRDALEKLQANPQIDLLVTDINMPEIDGLTLLSKIRDLNLDI
KAVIVSAYEDLKNIRRAMNQGAFDFITKPIDFQELESTMNRALEYVQEIKNKSSLVSSDQLPEVQSKEIYVNNQLVLEKQ
QEINHSTNLDYIDFQEIETGVNQLINHLRLYQQDFPLASPQILQNAKDIDLASLLLGLPTTIQSMKDKTNQP

Sequences:

>Translated_232_residues
MTEYILFVDDEPLIKRLVTHYFRHKIRQGEYEFIFAHNGRDALEKLQANPQIDLLVTDINMPEIDGLTLLSKIRDLNLDI
KAVIVSAYEDLKNIRRAMNQGAFDFITKPIDFQELESTMNRALEYVQEIKNKSSLVSSDQLPEVQSKEIYVNNQLVLEKQ
QEINHSTNLDYIDFQEIETGVNQLINHLRLYQQDFPLASPQILQNAKDIDLASLLLGLPTTIQSMKDKTNQP
>Mature_231_residues
TEYILFVDDEPLIKRLVTHYFRHKIRQGEYEFIFAHNGRDALEKLQANPQIDLLVTDINMPEIDGLTLLSKIRDLNLDIK
AVIVSAYEDLKNIRRAMNQGAFDFITKPIDFQELESTMNRALEYVQEIKNKSSLVSSDQLPEVQSKEIYVNNQLVLEKQQ
EINHSTNLDYIDFQEIETGVNQLINHLRLYQQDFPLASPQILQNAKDIDLASLLLGLPTTIQSMKDKTNQP

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=143, Percent_Identity=32.8671328671329, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=36.6666666666667, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790299, Length=91, Percent_Identity=39.5604395604396, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693157, Length=128, Percent_Identity=29.6875, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788905, Length=121, Percent_Identity=28.9256198347107, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 26847; Mature: 26716

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEYILFVDDEPLIKRLVTHYFRHKIRQGEYEFIFAHNGRDALEKLQANPQIDLLVTDIN
CCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCCCEEEEEEECC
MPEIDGLTLLSKIRDLNLDIKAVIVSAYEDLKNIRRAMNQGAFDFITKPIDFQELESTMN
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHH
RALEYVQEIKNKSSLVSSDQLPEVQSKEIYVNNQLVLEKQQEINHSTNLDYIDFQEIETG
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEHHHHHCCCCCCCCCCHHHHHHHH
VNQLINHLRLYQQDFPLASPQILQNAKDIDLASLLLGLPTTIQSMKDKTNQP
HHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
TEYILFVDDEPLIKRLVTHYFRHKIRQGEYEFIFAHNGRDALEKLQANPQIDLLVTDIN
CCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCCCEEEEEEECC
MPEIDGLTLLSKIRDLNLDIKAVIVSAYEDLKNIRRAMNQGAFDFITKPIDFQELESTMN
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHH
RALEYVQEIKNKSSLVSSDQLPEVQSKEIYVNNQLVLEKQQEINHSTNLDYIDFQEIETG
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEHHHHHCCCCCCCCCCHHHHHHHH
VNQLINHLRLYQQDFPLASPQILQNAKDIDLASLLLGLPTTIQSMKDKTNQP
HHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]