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The map label for this gene is pilH [H]

Identifier: 17229656

GI number: 17229656

Start: 2599281

End: 2599658

Strand: Reverse

Name: pilH [H]

Synonym: all2164

Alternate gene names: 17229656

Gene position: 2599658-2599281 (Counterclockwise)

Preceding gene: 17229657

Following gene: 17229655

Centisome position: 40.53

GC content: 37.57

Gene sequence:

>378_bases
GTGAGTATTACCTTAGTCGGCAAAATTTTGATTGTTGAAGACTCACCTAGTGAATTAGAACTGATGAGTCATTATTTACA
AGAGAGTGGTTATGACGTAATTAAGGCGGCTGGTGCAAAGGAAGCTATAGAGAAAGCTTTATTAGAAAATCCTGATGTAA
TTGTCACTGATGTTGTCATGCCGGGAATGAGTGGATTTGAGTTATGTCGTTCCTTGAAAAAACATCCACTTACAGAAAAA
CTCCCGATAGTAATTTGCAGTTCTAAAAACCAAGAAATAGACCGTTTGTGGGCAATGAAACAAGGTGCAGATGCCTATAT
TACAAAACCCTATACCCGCGAAAATCTGCTGCGTACTATTAAATCTGTAGTGATTTAA

Upstream 100 bases:

>100_bases
AAAATGGTCAGGTCTTCAGGCTATTTAACTAAGCCTTTTGACCAGTCGGAATTATTAAAAATGGTGTTTAAACATATTAC
TTAAGGCAGGAGATTGAAGA

Downstream 100 bases:

>100_bases
ATCAATGGATAACTCACAAAGTTTAATGACTCCTCTGTCACCTCAAAATAAATCAGGAGATGGTTATCTAAAATTTTACC
TCAATCAGCAAAGTGCTGCT

Product: two-component system, regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 124

Protein sequence:

>125_residues
MSITLVGKILIVEDSPSELELMSHYLQESGYDVIKAAGAKEAIEKALLENPDVIVTDVVMPGMSGFELCRSLKKHPLTEK
LPIVICSSKNQEIDRLWAMKQGADAYITKPYTRENLLRTIKSVVI

Sequences:

>Translated_125_residues
MSITLVGKILIVEDSPSELELMSHYLQESGYDVIKAAGAKEAIEKALLENPDVIVTDVVMPGMSGFELCRSLKKHPLTEK
LPIVICSSKNQEIDRLWAMKQGADAYITKPYTRENLLRTIKSVVI
>Mature_124_residues
SITLVGKILIVEDSPSELELMSHYLQESGYDVIKAAGAKEAIEKALLENPDVIVTDVVMPGMSGFELCRSLKKHPLTEKL
PIVICSSKNQEIDRLWAMKQGADAYITKPYTRENLLRTIKSVVI

Specific function: May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=32.4786324786325, Blast_Score=82, Evalue=9e-18,
Organism=Escherichia coli, GI1788394, Length=117, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=2e-16,
Organism=Escherichia coli, GI1789809, Length=117, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=2e-16,
Organism=Escherichia coli, GI1790860, Length=121, Percent_Identity=35.5371900826446, Blast_Score=75, Evalue=1e-15,
Organism=Escherichia coli, GI87082012, Length=115, Percent_Identity=25.2173913043478, Blast_Score=67, Evalue=4e-13,
Organism=Escherichia coli, GI1786911, Length=104, Percent_Identity=28.8461538461538, Blast_Score=63, Evalue=5e-12,
Organism=Escherichia coli, GI1788713, Length=104, Percent_Identity=34.6153846153846, Blast_Score=60, Evalue=4e-11,
Organism=Escherichia coli, GI1787229, Length=119, Percent_Identity=28.5714285714286, Blast_Score=60, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 13918; Mature: 13786

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITLVGKILIVEDSPSELELMSHYLQESGYDVIKAAGAKEAIEKALLENPDVIVTDVVM
CCEEEEEEEEEEECCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCCEEEEEHHC
PGMSGFELCRSLKKHPLTEKLPIVICSSKNQEIDRLWAMKQGADAYITKPYTRENLLRTI
CCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEECCCCHHHHHHHH
KSVVI
HHHCC
>Mature Secondary Structure 
SITLVGKILIVEDSPSELELMSHYLQESGYDVIKAAGAKEAIEKALLENPDVIVTDVVM
CEEEEEEEEEEECCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCCEEEEEHHC
PGMSGFELCRSLKKHPLTEKLPIVICSSKNQEIDRLWAMKQGADAYITKPYTRENLLRTI
CCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEECCCCHHHHHHHH
KSVVI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7908398; 10984043 [H]