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The map label for this gene is thrC [H]

Identifier: 17229564

GI number: 17229564

Start: 2478215

End: 2479306

Strand: Reverse

Name: thrC [H]

Synonym: all2072

Alternate gene names: 17229564

Gene position: 2479306-2478215 (Counterclockwise)

Preceding gene: 17229569

Following gene: 17229562

Centisome position: 38.66

GC content: 48.99

Gene sequence:

>1092_bases
GTGACTTTGAGCTTGTCTGTTGCTAAATCTCATCGCCAACCCTGGCCCGGACTGATAGAAGCCTATCGTGAGTACTTACC
TGTCAGCGACAAAACGCCAGTTGTGACTTTGTTGGAAGGTAACACTCCTTTAATTCCGGTGCCAGCGATCGCAGAACGTA
TCGGTAGACAAGTAAGTGTGTTTGTGAAATACGATGGTCTCAACCCCACTGGCAGTTTCAAAGACAGGGGGATGACTATG
GCGATTTCCAAAGCTAAGGAAGACGGAGCCAAAGCGGTCATTTGTGCGAGTACAGGCAATACCTCAGCCGCAGCCGCAGC
CTATGCTCGTCGTGGTGGGATGAAGGCTTTTGTATTGATTCCTGATGGTTATGTTGCCTTGGGTAAGCTGGCGCAAGCAC
TACTTTATGGTGCAGAAGTATTGGCAATTAAAGGCAACTTCGACCAAGCTCTAGAAATCGTCCGGGAAATGGCAGAAAGT
TATCCCATCACGTTAGTAAACTCAGTCAATCCCTACCGCTTGGAAGGTCAAAAAACAGGAGCTTTTGAAGTGGTGGATGC
TTTGGGTAATGCCCCAGACTGGTTGTGCATCCCAGTTGGTAACGCGGGAAATATCACAGCATATTGGATGGGTTTTTGTC
AATATCATCAAGCCGGGAAATGCGATCGCCTACCCCAGATGATGGGCTTCCAAGCCGCAGGTGCAGCCCCCTTGGTAAAT
GGTCAGCCTGTATCCCATCCCGAAACCATCGCTACCGCCATTCGCATTGGCAAACCAGCGAGTTGGGATAAAGCGATCGC
AGCCCAATCAGCCAGTCAAGGAAGTTTTAACGCCGTCACTGATGAAGAAATTCTCGACGCATACCGACTATTGGCATCAT
CAGAAGGTATTTTCTGCGAACCCGCTAGCGCTGCTTCCGTCGCCGGCTTATTAAAAGTCAAAGACCAAGTACCCACAGGC
GCAACAGTCGTATGTGTCCTCACAGGTAACGGTCTTAAAGACCCAGATACAGCAATTAAACACAGTCACAGCCAATTCAA
ACAAGGTATTGAGGCAGATTTAAGCTCTGTAGCCAAGGCGATGGGATTTTAG

Upstream 100 bases:

>100_bases
CGCAAAAAGAGGGACTAGAGTTTAAACATATTCCTTCTTTAACTTTCCCACTTATGAAAATCTTCAATATCCAATCCTTA
GCGAAAAACATTTAAATCCT

Downstream 100 bases:

>100_bases
GAGTTTAGAGACGCGATTAATCGCGTCTGTACAATTGTCATTACTCATTACTTCCCCTGCTCCCCTACTCCCCACTCCCC
CGTCCTCGTTCCTTTGCCAA

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTLSLSVAKSHRQPWPGLIEAYREYLPVSDKTPVVTLLEGNTPLIPVPAIAERIGRQVSVFVKYDGLNPTGSFKDRGMTM
AISKAKEDGAKAVICASTGNTSAAAAAYARRGGMKAFVLIPDGYVALGKLAQALLYGAEVLAIKGNFDQALEIVREMAES
YPITLVNSVNPYRLEGQKTGAFEVVDALGNAPDWLCIPVGNAGNITAYWMGFCQYHQAGKCDRLPQMMGFQAAGAAPLVN
GQPVSHPETIATAIRIGKPASWDKAIAAQSASQGSFNAVTDEEILDAYRLLASSEGIFCEPASAASVAGLLKVKDQVPTG
ATVVCVLTGNGLKDPDTAIKHSHSQFKQGIEADLSSVAKAMGF

Sequences:

>Translated_363_residues
MTLSLSVAKSHRQPWPGLIEAYREYLPVSDKTPVVTLLEGNTPLIPVPAIAERIGRQVSVFVKYDGLNPTGSFKDRGMTM
AISKAKEDGAKAVICASTGNTSAAAAAYARRGGMKAFVLIPDGYVALGKLAQALLYGAEVLAIKGNFDQALEIVREMAES
YPITLVNSVNPYRLEGQKTGAFEVVDALGNAPDWLCIPVGNAGNITAYWMGFCQYHQAGKCDRLPQMMGFQAAGAAPLVN
GQPVSHPETIATAIRIGKPASWDKAIAAQSASQGSFNAVTDEEILDAYRLLASSEGIFCEPASAASVAGLLKVKDQVPTG
ATVVCVLTGNGLKDPDTAIKHSHSQFKQGIEADLSSVAKAMGF
>Mature_362_residues
TLSLSVAKSHRQPWPGLIEAYREYLPVSDKTPVVTLLEGNTPLIPVPAIAERIGRQVSVFVKYDGLNPTGSFKDRGMTMA
ISKAKEDGAKAVICASTGNTSAAAAAYARRGGMKAFVLIPDGYVALGKLAQALLYGAEVLAIKGNFDQALEIVREMAESY
PITLVNSVNPYRLEGQKTGAFEVVDALGNAPDWLCIPVGNAGNITAYWMGFCQYHQAGKCDRLPQMMGFQAAGAAPLVNG
QPVSHPETIATAIRIGKPASWDKAIAAQSASQGSFNAVTDEEILDAYRLLASSEGIFCEPASAASVAGLLKVKDQVPTGA
TVVCVLTGNGLKDPDTAIKHSHSQFKQGIEADLSSVAKAMGF

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17508781, Length=301, Percent_Identity=25.2491694352159, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322631, Length=317, Percent_Identity=24.9211356466877, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 38276; Mature: 38145

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSLSVAKSHRQPWPGLIEAYREYLPVSDKTPVVTLLEGNTPLIPVPAIAERIGRQVSV
CEEEEEEHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECHHHHHHCCCEEEE
FVKYDGLNPTGSFKDRGMTMAISKAKEDGAKAVICASTGNTSAAAAAYARRGGMKAFVLI
EEEECCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEE
PDGYVALGKLAQALLYGAEVLAIKGNFDQALEIVREMAESYPITLVNSVNPYRLEGQKTG
CCCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCC
AFEVVDALGNAPDWLCIPVGNAGNITAYWMGFCQYHQAGKCDRLPQMMGFQAAGAAPLVN
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCC
GQPVSHPETIATAIRIGKPASWDKAIAAQSASQGSFNAVTDEEILDAYRLLASSEGIFCE
CCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEC
PASAASVAGLLKVKDQVPTGATVVCVLTGNGLKDPDTAIKHSHSQFKQGIEADLSSVAKA
CCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
MGF
HCC
>Mature Secondary Structure 
TLSLSVAKSHRQPWPGLIEAYREYLPVSDKTPVVTLLEGNTPLIPVPAIAERIGRQVSV
EEEEEEHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECHHHHHHCCCEEEE
FVKYDGLNPTGSFKDRGMTMAISKAKEDGAKAVICASTGNTSAAAAAYARRGGMKAFVLI
EEEECCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEE
PDGYVALGKLAQALLYGAEVLAIKGNFDQALEIVREMAESYPITLVNSVNPYRLEGQKTG
CCCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCC
AFEVVDALGNAPDWLCIPVGNAGNITAYWMGFCQYHQAGKCDRLPQMMGFQAAGAAPLVN
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCC
GQPVSHPETIATAIRIGKPASWDKAIAAQSASQGSFNAVTDEEILDAYRLLASSEGIFCE
CCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEC
PASAASVAGLLKVKDQVPTGATVVCVLTGNGLKDPDTAIKHSHSQFKQGIEADLSSVAKA
CCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
MGF
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]