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The map label for this gene is mhpC2 [H]

Identifier: 17229560

GI number: 17229560

Start: 2474972

End: 2475907

Strand: Reverse

Name: mhpC2 [H]

Synonym: all2068

Alternate gene names: 17229560

Gene position: 2475907-2474972 (Counterclockwise)

Preceding gene: 17229561

Following gene: 17229559

Centisome position: 38.6

GC content: 38.14

Gene sequence:

>936_bases
ATGAAAGATTGGTGGCAAGAGACTTTCCCCAAGGGGCGGCAAAGTCTGATAATTAGTGACGTTCATGGGTATCCTGTACA
AATTGCATACGGTGAAAAAGGTACAGGTAGGCCATTATTTCTCATACACGGTATGGGTAGTTGGAGCTATAATTGGCGTT
ATAGTGTAGCTCCATTATCTAAGTATTTCCGCGTCATTTGTGTAGATGCTAAAGGTTTCGGTTTTTCTGATAAACCTTGC
TTGCGTCAAGAAAAGAATGGGCATCAAGTCATTGAATTAGAACGCATTATTCAATGTTTATGTGATGAACCAGCTATTGT
TGCAGCTGAATCCTTAGGTGCATTGGTAGCTCTTGCCTTAGCACAAAAAAATGCCGAATTAATCGGACGGTTAGTAGTAA
TTAATGCGCCAATTTTTGCTGATCGTTTACCCCATTGGGCAATGTCTATACTTGCCCAAACACCAATAGAAATATTACAA
ACAATCGATGATTTGCGTTTAGCTTATTTATTTGCGCCCATAGTTCGAGAAGTTATGGCGGTAGAAAGACGTAAAGTACT
GTTTGATCCGTCAATTTTGACTCAAGAAGATGTGTATTGGATTACTTACCCATTTATTGAAATTCCAGGAACTTTGGTTA
AAGTTGCCGAAGAGTTACAAATAGCGGCAAGAGAAATCGAGAACTGGCAAGCAAATAAACCAAATATGCTCAGTGAAATT
CAAAATAAGTTGAATTTAATTGAGGCTCCCACATTAATCTTATGGGGCGATAAAGATAGCTGGTTTCCTGCCAGCCACGG
GAAAAAATTACATCAACACTTACCTAATTCCAAGTTGCAAATTTTAGATAACTGCTATCATGATGCTTCCACCGGTTCTG
CAAAAGTTGTCAACAAAGAAATTTTACAATTTCTCAAGGAGACAGATTTTTTATAA

Upstream 100 bases:

>100_bases
ACAGTCAACAGTCAACAGTCACCCTCCTCCATCTCCCCATTCGCCAATTTCTGCTGTAGAATGCCTTAACGAGTGTTGAG
ATCACTCATTGAGCAAAGAC

Downstream 100 bases:

>100_bases
CCATGTTTATTTAATTAAAAAACATAAATTATTCCAACTATAGGAATCCTATTTGATTTGTGAACAAGACCAAGAGATAA
TACGGAGAGGGATAAAAGTC

Product: hypothetical protein

Products: NA

Alternate protein names: 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase 2; 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase 2; 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase 2 [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKDWWQETFPKGRQSLIISDVHGYPVQIAYGEKGTGRPLFLIHGMGSWSYNWRYSVAPLSKYFRVICVDAKGFGFSDKPC
LRQEKNGHQVIELERIIQCLCDEPAIVAAESLGALVALALAQKNAELIGRLVVINAPIFADRLPHWAMSILAQTPIEILQ
TIDDLRLAYLFAPIVREVMAVERRKVLFDPSILTQEDVYWITYPFIEIPGTLVKVAEELQIAAREIENWQANKPNMLSEI
QNKLNLIEAPTLILWGDKDSWFPASHGKKLHQHLPNSKLQILDNCYHDASTGSAKVVNKEILQFLKETDFL

Sequences:

>Translated_311_residues
MKDWWQETFPKGRQSLIISDVHGYPVQIAYGEKGTGRPLFLIHGMGSWSYNWRYSVAPLSKYFRVICVDAKGFGFSDKPC
LRQEKNGHQVIELERIIQCLCDEPAIVAAESLGALVALALAQKNAELIGRLVVINAPIFADRLPHWAMSILAQTPIEILQ
TIDDLRLAYLFAPIVREVMAVERRKVLFDPSILTQEDVYWITYPFIEIPGTLVKVAEELQIAAREIENWQANKPNMLSEI
QNKLNLIEAPTLILWGDKDSWFPASHGKKLHQHLPNSKLQILDNCYHDASTGSAKVVNKEILQFLKETDFL
>Mature_311_residues
MKDWWQETFPKGRQSLIISDVHGYPVQIAYGEKGTGRPLFLIHGMGSWSYNWRYSVAPLSKYFRVICVDAKGFGFSDKPC
LRQEKNGHQVIELERIIQCLCDEPAIVAAESLGALVALALAQKNAELIGRLVVINAPIFADRLPHWAMSILAQTPIEILQ
TIDDLRLAYLFAPIVREVMAVERRKVLFDPSILTQEDVYWITYPFIEIPGTLVKVAEELQIAAREIENWQANKPNMLSEI
QNKLNLIEAPTLILWGDKDSWFPASHGKKLHQHLPNSKLQILDNCYHDASTGSAKVVNKEILQFLKETDFL

Specific function: Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. MhpC family [H]

Homologues:

Organism=Escherichia coli, GI87081721, Length=292, Percent_Identity=25.3424657534247, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17554012, Length=300, Percent_Identity=24, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.-; 3.1.1.-

Molecular weight: Translated: 35349; Mature: 35349

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDWWQETFPKGRQSLIISDVHGYPVQIAYGEKGTGRPLFLIHGMGSWSYNWRYSVAPLS
CCCHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEEECCCCCCCEEEECCHHH
KYFRVICVDAKGFGFSDKPCLRQEKNGHQVIELERIIQCLCDEPAIVAAESLGALVALAL
HCEEEEEEECCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
AQKNAELIGRLVVINAPIFADRLPHWAMSILAQTPIEILQTIDDLRLAYLFAPIVREVMA
HHCCHHHHEEEEEEECCHHHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
VERRKVLFDPSILTQEDVYWITYPFIEIPGTLVKVAEELQIAAREIENWQANKPNMLSEI
HHHHHHEECCCCCCCCCEEEEEECHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
QNKLNLIEAPTLILWGDKDSWFPASHGKKLHQHLPNSKLQILDNCYHDASTGSAKVVNKE
HHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHH
ILQFLKETDFL
HHHHHHHCCCC
>Mature Secondary Structure
MKDWWQETFPKGRQSLIISDVHGYPVQIAYGEKGTGRPLFLIHGMGSWSYNWRYSVAPLS
CCCHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEEECCCCCCCEEEECCHHH
KYFRVICVDAKGFGFSDKPCLRQEKNGHQVIELERIIQCLCDEPAIVAAESLGALVALAL
HCEEEEEEECCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
AQKNAELIGRLVVINAPIFADRLPHWAMSILAQTPIEILQTIDDLRLAYLFAPIVREVMA
HHCCHHHHEEEEEEECCHHHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
VERRKVLFDPSILTQEDVYWITYPFIEIPGTLVKVAEELQIAAREIENWQANKPNMLSEI
HHHHHHEECCCCCCCCCEEEEEECHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
QNKLNLIEAPTLILWGDKDSWFPASHGKKLHQHLPNSKLQILDNCYHDASTGSAKVVNKE
HHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHH
ILQFLKETDFL
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA