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The map label for this gene is crtI [H]

Identifier: 17229556

GI number: 17229556

Start: 2470593

End: 2472113

Strand: Direct

Name: crtI [H]

Synonym: alr2064

Alternate gene names: 17229556

Gene position: 2470593-2472113 (Clockwise)

Preceding gene: 17229552

Following gene: 17229563

Centisome position: 38.52

GC content: 43.92

Gene sequence:

>1521_bases
ATGTCCGTAACCTCAACTACTTCCCAAAATTCTTTGTTTGATGTCATCGTGATTGGGTCTGGCATTGGCGGACTAGTGAC
AGCAACCCAACTCGCAACCAAGGGAGCGAAAGTTCTGGTACTAGAAAGCTATATCATTCCTGGTGGAAGTGCTGGCTACT
TTGAGCGTCAAGGCTATCGTTTTGACGTTGGAGCTTCCATGATTTTTGGCTTAGGGAACAGAGGGACTACAAACTTACTC
ACCCGTGCTTTACAAGCTGTAAATAGTAGTGTAGATGCGATCGCCGATCCTGTACAAATCCACTACCACTTACCCAACAA
CTTAAACCTGAAAGTTGACCGGGTTTATGATAAGTTTTTGCAAAATCTTGCTGCTTACTTTCCTCATGAAAAAGAGGGGA
TTCGTGGCTTTTATGACGAATGTTGGCAAGTATTTAAGTGTCTCAACCGCATGGAGTTGTTGTCATTAGAAGAACCTCGG
TATTTGCTGCGATCGTTTTTGCAACATCCTTTAGCGTGTCTAGGTTTACTTAAGTATCTGCCTCAAAATGCTGGGGATAT
CGCCCGTCGCTACATCAAAGACCCAGAATTATTGAAATTTATCGATATAGAATGTTACTGCTGGTCTGTAGTGCCAGCAG
CGATGACACCGATGATTAATGCAGGTATGGTCTTTTCTGACAGGCATTATGGCGGTGTTAACTACCCCAAGGGTGGAGTA
GGTCAAATTGCCCAGAAGCTCGTAGAAGGCTTAGAAAAAGCTGGTGGCGAGATTCGATATCAAGCCAAAGTAGCAAAAAT
CATTACTGAAAAAGACTGTGCTGTCGGTGTGCAACTAACTAATGGTGAAATTTATCGAGGCAAACGGATAGTTTCTAATG
CTACACGGTGGGACACATTTGACAAATTACTACCTGTAGATCAAATACCATCTAATGAGAAAAAATGGCAACAGAACTAT
AAAAAATCACCCAGTTTTTTGAGTTTACACATAGGGGTCAAAGAGTCAGTCTTACCTCAAGGGACAGAATGCCATCATAT
TATCTTGGAAGATTGGCAAAATATGACCCAACCAGAAGGCACACTGTTTGTCTCCATACCCACATTGCTTGATCCAGAAT
TAGCCCCAGAAGGATACCATATAATTCATGCCTTTACGCCTAATTGGATGAATGATTGGCATGGGTTGTCTGTGAGTGAC
TACGAAGCGAAGAAAGAAGAGACAGCCTGGCGAATTATTGACAGACTAGAAAAGATATTTCCTGGCTTAGATGCAGGTTT
AGATTATTTAGAAGTAGGCACACCCCGTACCCATCGCCGCTTTTTAGGGCGAGAAGACGGCACTTATGGCCCCATTCCCA
GACGTAAACTGCGAGGATTGTTGTCCATGCCTTTTAATCGCACCGCTATCAAGGGACTGTATTGTGTAGGAGACAGTACA
TTTCCCGGACAGGGTTTAAATGCAGTCGCCTTTTCTGGCTTCGCCTGCGCCCATCGTATCGCCGTCGATTTGGGGTTGTG
A

Upstream 100 bases:

>100_bases
TTATTTACGATAAATTTGAGGAAATTGCGTAAGCTTTACCAGATATAGATGTATTATGAAATACGGTTTGGCTGGTTAAT
TCCATGTAAGTGCAGCTTTT

Downstream 100 bases:

>100_bases
TGGGATGAGGAAGGCGGGAAGAAATACAGCACTAGTTAAGGTTGGAGACTTCCAGATAAAAAATATTGAAACTGTAGCGA
CTGTCTTGAAAGTCAAGCGA

Product: hypothetical protein

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MSVTSTTSQNSLFDVIVIGSGIGGLVTATQLATKGAKVLVLESYIIPGGSAGYFERQGYRFDVGASMIFGLGNRGTTNLL
TRALQAVNSSVDAIADPVQIHYHLPNNLNLKVDRVYDKFLQNLAAYFPHEKEGIRGFYDECWQVFKCLNRMELLSLEEPR
YLLRSFLQHPLACLGLLKYLPQNAGDIARRYIKDPELLKFIDIECYCWSVVPAAMTPMINAGMVFSDRHYGGVNYPKGGV
GQIAQKLVEGLEKAGGEIRYQAKVAKIITEKDCAVGVQLTNGEIYRGKRIVSNATRWDTFDKLLPVDQIPSNEKKWQQNY
KKSPSFLSLHIGVKESVLPQGTECHHIILEDWQNMTQPEGTLFVSIPTLLDPELAPEGYHIIHAFTPNWMNDWHGLSVSD
YEAKKEETAWRIIDRLEKIFPGLDAGLDYLEVGTPRTHRRFLGREDGTYGPIPRRKLRGLLSMPFNRTAIKGLYCVGDST
FPGQGLNAVAFSGFACAHRIAVDLGL

Sequences:

>Translated_506_residues
MSVTSTTSQNSLFDVIVIGSGIGGLVTATQLATKGAKVLVLESYIIPGGSAGYFERQGYRFDVGASMIFGLGNRGTTNLL
TRALQAVNSSVDAIADPVQIHYHLPNNLNLKVDRVYDKFLQNLAAYFPHEKEGIRGFYDECWQVFKCLNRMELLSLEEPR
YLLRSFLQHPLACLGLLKYLPQNAGDIARRYIKDPELLKFIDIECYCWSVVPAAMTPMINAGMVFSDRHYGGVNYPKGGV
GQIAQKLVEGLEKAGGEIRYQAKVAKIITEKDCAVGVQLTNGEIYRGKRIVSNATRWDTFDKLLPVDQIPSNEKKWQQNY
KKSPSFLSLHIGVKESVLPQGTECHHIILEDWQNMTQPEGTLFVSIPTLLDPELAPEGYHIIHAFTPNWMNDWHGLSVSD
YEAKKEETAWRIIDRLEKIFPGLDAGLDYLEVGTPRTHRRFLGREDGTYGPIPRRKLRGLLSMPFNRTAIKGLYCVGDST
FPGQGLNAVAFSGFACAHRIAVDLGL
>Mature_505_residues
SVTSTTSQNSLFDVIVIGSGIGGLVTATQLATKGAKVLVLESYIIPGGSAGYFERQGYRFDVGASMIFGLGNRGTTNLLT
RALQAVNSSVDAIADPVQIHYHLPNNLNLKVDRVYDKFLQNLAAYFPHEKEGIRGFYDECWQVFKCLNRMELLSLEEPRY
LLRSFLQHPLACLGLLKYLPQNAGDIARRYIKDPELLKFIDIECYCWSVVPAAMTPMINAGMVFSDRHYGGVNYPKGGVG
QIAQKLVEGLEKAGGEIRYQAKVAKIITEKDCAVGVQLTNGEIYRGKRIVSNATRWDTFDKLLPVDQIPSNEKKWQQNYK
KSPSFLSLHIGVKESVLPQGTECHHIILEDWQNMTQPEGTLFVSIPTLLDPELAPEGYHIIHAFTPNWMNDWHGLSVSDY
EAKKEETAWRIIDRLEKIFPGLDAGLDYLEVGTPRTHRRFLGREDGTYGPIPRRKLRGLLSMPFNRTAIKGLYCVGDSTF
PGQGLNAVAFSGFACAHRIAVDLGL

Specific function: This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI203098013, Length=485, Percent_Identity=24.7422680412371, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17540238, Length=545, Percent_Identity=24.4036697247706, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 56479; Mature: 56347

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTSTTSQNSLFDVIVIGSGIGGLVTATQLATKGAKVLVLESYIIPGGSAGYFERQGYR
CCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCEE
FDVGASMIFGLGNRGTTNLLTRALQAVNSSVDAIADPVQIHYHLPNNLNLKVDRVYDKFL
EECCCHHEEECCCCCHHHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCCEEHHHHHHHHH
QNLAAYFPHEKEGIRGFYDECWQVFKCLNRMELLSLEEPRYLLRSFLQHPLACLGLLKYL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
PQNAGDIARRYIKDPELLKFIDIECYCWSVVPAAMTPMINAGMVFSDRHYGGVNYPKGGV
CCCHHHHHHHHCCCCHHEEEEEEEEEEEHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCH
GQIAQKLVEGLEKAGGEIRYQAKVAKIITEKDCAVGVQLTNGEIYRGKRIVSNATRWDTF
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCEEEEEEECCCEECCCHHHCCCHHHCHH
DKLLPVDQIPSNEKKWQQNYKKSPSFLSLHIGVKESVLPQGTECHHIILEDWQNMTQPEG
HHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECCHHHCCCCCCCCHHHHHHHHHCCCCCCC
TLFVSIPTLLDPELAPEGYHIIHAFTPNWMNDWHGLSVSDYEAKKEETAWRIIDRLEKIF
EEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
PGLDAGLDYLEVGTPRTHRRFLGREDGTYGPIPRRKLRGLLSMPFNRTAIKGLYCVGDST
CCCCCCCCCEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCHHHCEEEEECCCC
FPGQGLNAVAFSGFACAHRIAVDLGL
CCCCCCCHHHHCCHHHHHHHHEECCC
>Mature Secondary Structure 
SVTSTTSQNSLFDVIVIGSGIGGLVTATQLATKGAKVLVLESYIIPGGSAGYFERQGYR
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCEE
FDVGASMIFGLGNRGTTNLLTRALQAVNSSVDAIADPVQIHYHLPNNLNLKVDRVYDKFL
EECCCHHEEECCCCCHHHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCCEEHHHHHHHHH
QNLAAYFPHEKEGIRGFYDECWQVFKCLNRMELLSLEEPRYLLRSFLQHPLACLGLLKYL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
PQNAGDIARRYIKDPELLKFIDIECYCWSVVPAAMTPMINAGMVFSDRHYGGVNYPKGGV
CCCHHHHHHHHCCCCHHEEEEEEEEEEEHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCH
GQIAQKLVEGLEKAGGEIRYQAKVAKIITEKDCAVGVQLTNGEIYRGKRIVSNATRWDTF
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCEEEEEEECCCEECCCHHHCCCHHHCHH
DKLLPVDQIPSNEKKWQQNYKKSPSFLSLHIGVKESVLPQGTECHHIILEDWQNMTQPEG
HHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECCHHHCCCCCCCCHHHHHHHHHCCCCCCC
TLFVSIPTLLDPELAPEGYHIIHAFTPNWMNDWHGLSVSDYEAKKEETAWRIIDRLEKIF
EEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
PGLDAGLDYLEVGTPRTHRRFLGREDGTYGPIPRRKLRGLLSMPFNRTAIKGLYCVGDST
CCCCCCCCCEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCHHHCEEEEECCCC
FPGQGLNAVAFSGFACAHRIAVDLGL
CCCCCCCHHHHCCHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592436 [H]