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The map label for this gene is pyrD [H]

Identifier: 17229404

GI number: 17229404

Start: 2291711

End: 2292742

Strand: Direct

Name: pyrD [H]

Synonym: alr1912

Alternate gene names: 17229404

Gene position: 2291711-2292742 (Clockwise)

Preceding gene: 17229403

Following gene: 17229405

Centisome position: 35.73

GC content: 43.6

Gene sequence:

>1032_bases
ATGGATTTAACTACTAATTATCTAGGATTACGATTGCGATCGCCACTTGTCCCGTCAGCGTCTCCCATGTCTGGAGAAAT
AGACAATATTCTCTGGATGGAAGATGCAGGCGCAGCAGCAGTGGTTCTACCCTCGTTGTTTGAAGAACAGTTGAGTTTAG
AAAGTTATGAGTTACATCATCACTTAACTTATGGAACCGAGAGTTTCCCTGAGTCCTTAACATATTTCCCTGAACACCAA
GATTTTCGCCTGGGGTCAGAAGAATACTTAAACCTGATTCAAAAAACTAAGGAAAAGGTAAAAATCCCCATCATTGCCAG
TTTGAATGGTTCTTCACTAGATGGCTGGACTGAATACGCCAGAATGATTGAGCAAGCAGGTGCAGCAGCCTTGGAGTTAA
ATACTTATTCTGTTCATACCGATCCTGAATTAACTAGCGAACAAATAGAGCAGAGTTATATCAATATGCTCAAAGTTGTC
AAAGCATCTGTACAGATTCCCGTAGCAATTAAACTGAGTCCATATTTTACCAATATGGCAAACATGGCCAAGCGTTTAGA
TGATGCTGGGGCTGATGCTTTGGTGCTATTTAACCGTTTTTACCAACCAGATATTAATTTAGAAACCTTAGAAGTACAGC
CTCATGTACTGTTAAGCACCCCTCAAGCAATGCGCTTACCTCTGCGTTGGATTGCCATTCTTTATGGTCACATCAATGCT
CACCTCGCTGCTACCAGTGGCATTCACAACGGGCATGATGTCTTAAAAATGCTCATGGCGGGAGCCAATATTACGATGTT
GTGTTCTGTCTTATTGCGACATGGCATAGACCATATCAGGTGTATCGAACAGGAAATGAGCCAATGGATGGAAAAACATG
AATACGAATCTGTGCAGCAACTCCAAGGAAGCATGAGCCAAAAACACTGCCCCAACCCCAGCGCCTTTGAACGCGCTCAA
TATATGCGGGCGCTGCAAACCTATCAACCAGACTGGGGGCGGGTTTACGAGCCTTCCCATTATCACGGGTAA

Upstream 100 bases:

>100_bases
GCAATAGAGCCTAAATATACTCAGAAATTATTCATACTGACGCACCCTACCAAACCTGTTGACTGTTGACTATATTTAAA
AGTTTTTCAGGAAAATACTC

Downstream 100 bases:

>100_bases
TACAAATTCAAAATTCAAAATTCAAAATTCGTCTTGAAAAGTTTCCTACGGCGGGAAACCCGCCTACAGAACTTTTCGCA
AAATTCAAAATTCAAAATAC

Product: dihydroorotate dehydrogenase 2

Products: NA

Alternate protein names: DHOdehase; DHOD; DHODase; Dihydroorotate oxidase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MDLTTNYLGLRLRSPLVPSASPMSGEIDNILWMEDAGAAAVVLPSLFEEQLSLESYELHHHLTYGTESFPESLTYFPEHQ
DFRLGSEEYLNLIQKTKEKVKIPIIASLNGSSLDGWTEYARMIEQAGAAALELNTYSVHTDPELTSEQIEQSYINMLKVV
KASVQIPVAIKLSPYFTNMANMAKRLDDAGADALVLFNRFYQPDINLETLEVQPHVLLSTPQAMRLPLRWIAILYGHINA
HLAATSGIHNGHDVLKMLMAGANITMLCSVLLRHGIDHIRCIEQEMSQWMEKHEYESVQQLQGSMSQKHCPNPSAFERAQ
YMRALQTYQPDWGRVYEPSHYHG

Sequences:

>Translated_343_residues
MDLTTNYLGLRLRSPLVPSASPMSGEIDNILWMEDAGAAAVVLPSLFEEQLSLESYELHHHLTYGTESFPESLTYFPEHQ
DFRLGSEEYLNLIQKTKEKVKIPIIASLNGSSLDGWTEYARMIEQAGAAALELNTYSVHTDPELTSEQIEQSYINMLKVV
KASVQIPVAIKLSPYFTNMANMAKRLDDAGADALVLFNRFYQPDINLETLEVQPHVLLSTPQAMRLPLRWIAILYGHINA
HLAATSGIHNGHDVLKMLMAGANITMLCSVLLRHGIDHIRCIEQEMSQWMEKHEYESVQQLQGSMSQKHCPNPSAFERAQ
YMRALQTYQPDWGRVYEPSHYHG
>Mature_343_residues
MDLTTNYLGLRLRSPLVPSASPMSGEIDNILWMEDAGAAAVVLPSLFEEQLSLESYELHHHLTYGTESFPESLTYFPEHQ
DFRLGSEEYLNLIQKTKEKVKIPIIASLNGSSLDGWTEYARMIEQAGAAALELNTYSVHTDPELTSEQIEQSYINMLKVV
KASVQIPVAIKLSPYFTNMANMAKRLDDAGADALVLFNRFYQPDINLETLEVQPHVLLSTPQAMRLPLRWIAILYGHINA
HLAATSGIHNGHDVLKMLMAGANITMLCSVLLRHGIDHIRCIEQEMSQWMEKHEYESVQQLQGSMSQKHCPNPSAFERAQ
YMRALQTYQPDWGRVYEPSHYHG

Specific function: Unknown

COG id: COG0167

COG function: function code F; Dihydroorotate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082059, Length=325, Percent_Identity=20.6153846153846, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005720
- InterPro:   IPR012135
- InterPro:   IPR001295 [H]

Pfam domain/function: PF01180 DHO_dh [H]

EC number: =1.3.3.1 [H]

Molecular weight: Translated: 38830; Mature: 38830

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTTNYLGLRLRSPLVPSASPMSGEIDNILWMEDAGAAAVVLPSLFEEQLSLESYELHH
CCCCCCHHCEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHH
HLTYGTESFPESLTYFPEHQDFRLGSEEYLNLIQKTKEKVKIPIIASLNGSSLDGWTEYA
HEECCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHH
RMIEQAGAAALELNTYSVHTDPELTSEQIEQSYINMLKVVKASVQIPVAIKLSPYFTNMA
HHHHHCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHH
NMAKRLDDAGADALVLFNRFYQPDINLETLEVQPHVLLSTPQAMRLPLRWIAILYGHINA
HHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCEEEECCCHHHHHHHHHHHHHHHHHHH
HLAATSGIHNGHDVLKMLMAGANITMLCSVLLRHGIDHIRCIEQEMSQWMEKHEYESVQQ
HHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LQGSMSQKHCPNPSAFERAQYMRALQTYQPDWGRVYEPSHYHG
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDLTTNYLGLRLRSPLVPSASPMSGEIDNILWMEDAGAAAVVLPSLFEEQLSLESYELHH
CCCCCCHHCEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHH
HLTYGTESFPESLTYFPEHQDFRLGSEEYLNLIQKTKEKVKIPIIASLNGSSLDGWTEYA
HEECCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHH
RMIEQAGAAALELNTYSVHTDPELTSEQIEQSYINMLKVVKASVQIPVAIKLSPYFTNMA
HHHHHCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHH
NMAKRLDDAGADALVLFNRFYQPDINLETLEVQPHVLLSTPQAMRLPLRWIAILYGHINA
HHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCEEEECCCHHHHHHHHHHHHHHHHHHH
HLAATSGIHNGHDVLKMLMAGANITMLCSVLLRHGIDHIRCIEQEMSQWMEKHEYESVQQ
HHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LQGSMSQKHCPNPSAFERAQYMRALQTYQPDWGRVYEPSHYHG
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11029001 [H]