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The map label for this gene is xseA

Identifier: 17229266

GI number: 17229266

Start: 2132307

End: 2133545

Strand: Reverse

Name: xseA

Synonym: all1774

Alternate gene names: 17229266

Gene position: 2133545-2132307 (Counterclockwise)

Preceding gene: 17229268

Following gene: 17229265

Centisome position: 33.27

GC content: 45.68

Gene sequence:

>1239_bases
ATGGCTGCCGATTTTGCCGCTTCCGTAATTCTAGATACAGCACTTTCTGTATCTGGATTAACTGATTATCTCCGCTTACT
GCTGGAACATGATGAGCAACTACGGCAAGTGTGGGTAGTTGGGGAAGTTTCTAGTACTAATCATCACCGTAGTGGGTTAT
TTTTTACACTTCAAGATCCTGATGGTTCCGCAGCCATTAAGTGCGTGGTATGGAGTAGCCAAGTACCAAAACTTGCTCAA
CTACCCGTAGCGGGTGAACAACTAATTGTTTTGGGCAGTATTCGTTTATATCCACAAAGGGGAGAGTATCAATTATCAGT
CTGGCAAGCTGTACCTGCTGGAGTTGGTTTACAAGCACTACGTTATCAGCAACTCAAAAATCGCTTGTTGGCTGAGGGGT
TGTTCGACCCCCAAAGAAAGCGATCGCTTCCTATCCATCCCCAAACCATCGCCGTTGTTACTTCACCGACGGCTGCGGCT
TGGGGTGATATTCAAAAAACCCTTAAACATAGATATCCCGGTTTACACGTTTTATTTTCTCCTGCCACAGTCCAAGGTGA
ACAAGCTCCAGAATCTATTGTGAAGGCGATCGCACGAGTAGAAAAAGATGGTCGTGCTGAGGTACTAATCTTATCGCGTG
GGGGTGGTGCAGTAGAGGAATTAGCTTGCTTTAATGATGAGCGTGTAGTCCGCGCTGTAGCTGAGTGTTCCATACCCGTA
GTTACTGGGATTGGTCATCAACGAGACGAGTCTTTAGTAGATTTAGTAGCTGATGTTTGTGTGCATACACCGACGGCGGC
GGCAGAAAAGGTTGTACCATCACTGGCAGAATTATCCAATCAACATCGTCAGCGTATTATCGCCTTACATCAAGTTTTAC
TGCATACCCAAACCTCCGCAGAAAACCAACTACAAACACTACGCAACCGTTTGCAGAATCTCCGTTTAGATAGACACTTG
CAACAAGAGGCGCAAAAATTAAATTGGCAACGTCAGCGATTGTTGCAGTTAACAATGGGGCGATCGCAGCAAGCCAAGCA
GCACTTAGAACTTTTGCGACAAAAATTGATCAGCCTCGACCCCAAATCCGTATTACAGCGTGGTTATGCAGTGGTGAGAC
AAGAAAACGGTGCGATCGCTCGTTCTGCCGATGAATTAGCTGTAGGAAATGAGTTATTCATTCAACTGGCACAAGGTGAA
GTTAAGGCCAAAGTGATAGAAGTAGAACAACGGCAATGA

Upstream 100 bases:

>100_bases
GCAGACTAACTTGGATATTCTCCTCTATGCCCCCAGAGTTTTACAGCACTTCCCAATGCTACGATTTGGATAGACTTGTA
CTAATGTATTCAGATTTTTG

Downstream 100 bases:

>100_bases
GGGCAGAGAGATTAATGGTTAAGCGTAAGAACTCCGATAATTCGGATACTGTGGCACATGGTAATTACGAGGCAAAGGTT
GCAGAAATAGAAGCGATTAT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MAADFAASVILDTALSVSGLTDYLRLLLEHDEQLRQVWVVGEVSSTNHHRSGLFFTLQDPDGSAAIKCVVWSSQVPKLAQ
LPVAGEQLIVLGSIRLYPQRGEYQLSVWQAVPAGVGLQALRYQQLKNRLLAEGLFDPQRKRSLPIHPQTIAVVTSPTAAA
WGDIQKTLKHRYPGLHVLFSPATVQGEQAPESIVKAIARVEKDGRAEVLILSRGGGAVEELACFNDERVVRAVAECSIPV
VTGIGHQRDESLVDLVADVCVHTPTAAAEKVVPSLAELSNQHRQRIIALHQVLLHTQTSAENQLQTLRNRLQNLRLDRHL
QQEAQKLNWQRQRLLQLTMGRSQQAKQHLELLRQKLISLDPKSVLQRGYAVVRQENGAIARSADELAVGNELFIQLAQGE
VKAKVIEVEQRQ

Sequences:

>Translated_412_residues
MAADFAASVILDTALSVSGLTDYLRLLLEHDEQLRQVWVVGEVSSTNHHRSGLFFTLQDPDGSAAIKCVVWSSQVPKLAQ
LPVAGEQLIVLGSIRLYPQRGEYQLSVWQAVPAGVGLQALRYQQLKNRLLAEGLFDPQRKRSLPIHPQTIAVVTSPTAAA
WGDIQKTLKHRYPGLHVLFSPATVQGEQAPESIVKAIARVEKDGRAEVLILSRGGGAVEELACFNDERVVRAVAECSIPV
VTGIGHQRDESLVDLVADVCVHTPTAAAEKVVPSLAELSNQHRQRIIALHQVLLHTQTSAENQLQTLRNRLQNLRLDRHL
QQEAQKLNWQRQRLLQLTMGRSQQAKQHLELLRQKLISLDPKSVLQRGYAVVRQENGAIARSADELAVGNELFIQLAQGE
VKAKVIEVEQRQ
>Mature_411_residues
AADFAASVILDTALSVSGLTDYLRLLLEHDEQLRQVWVVGEVSSTNHHRSGLFFTLQDPDGSAAIKCVVWSSQVPKLAQL
PVAGEQLIVLGSIRLYPQRGEYQLSVWQAVPAGVGLQALRYQQLKNRLLAEGLFDPQRKRSLPIHPQTIAVVTSPTAAAW
GDIQKTLKHRYPGLHVLFSPATVQGEQAPESIVKAIARVEKDGRAEVLILSRGGGAVEELACFNDERVVRAVAECSIPVV
TGIGHQRDESLVDLVADVCVHTPTAAAEKVVPSLAELSNQHRQRIIALHQVLLHTQTSAENQLQTLRNRLQNLRLDRHLQ
QEAQKLNWQRQRLLQLTMGRSQQAKQHLELLRQKLISLDPKSVLQRGYAVVRQENGAIARSADELAVGNELFIQLAQGEV
KAKVIEVEQRQ

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=441, Percent_Identity=34.9206349206349, Blast_Score=223, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_NOSS1 (Q8YW42)

Other databases:

- EMBL:   BA000019
- PIR:   AH2027
- RefSeq:   NP_485814.1
- STRING:   Q8YW42
- GeneID:   1105366
- GenomeReviews:   BA000019_GR
- KEGG:   ana:all1774
- NMPDR:   fig|103690.1.peg.2081
- eggNOG:   COG1570
- HOGENOM:   HBG634411
- OMA:   THQTAYL
- PhylomeDB:   Q8YW42
- ProtClustDB:   PRK00286
- BioCyc:   NSP103690:ALL1774-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 45646; Mature: 45515

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAADFAASVILDTALSVSGLTDYLRLLLEHDEQLRQVWVVGEVSSTNHHRSGLFFTLQDP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEEEECC
DGSAAIKCVVWSSQVPKLAQLPVAGEQLIVLGSIRLYPQRGEYQLSVWQAVPAGVGLQAL
CCCCEEEEEEECCCCCHHHCCCCCCCCEEEEEEEEEECCCCCEEEEEEHHCCCCCCHHHH
RYQQLKNRLLAEGLFDPQRKRSLPIHPQTIAVVTSPTAAAWGDIQKTLKHRYPGLHVLFS
HHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEC
PATVQGEQAPESIVKAIARVEKDGRAEVLILSRGGGAVEELACFNDERVVRAVAECSIPV
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHCCCCE
VTGIGHQRDESLVDLVADVCVHTPTAAAEKVVPSLAELSNQHRQRIIALHQVLLHTQTSA
EECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ENQLQTLRNRLQNLRLDRHLQQEAQKLNWQRQRLLQLTMGRSQQAKQHLELLRQKLISLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
PKSVLQRGYAVVRQENGAIARSADELAVGNELFIQLAQGEVKAKVIEVEQRQ
HHHHHHHHHHEEEECCCCCCCCCHHHHCCHHHHEEECCCCCEEEEEEECCCC
>Mature Secondary Structure 
AADFAASVILDTALSVSGLTDYLRLLLEHDEQLRQVWVVGEVSSTNHHRSGLFFTLQDP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEEEECC
DGSAAIKCVVWSSQVPKLAQLPVAGEQLIVLGSIRLYPQRGEYQLSVWQAVPAGVGLQAL
CCCCEEEEEEECCCCCHHHCCCCCCCCEEEEEEEEEECCCCCEEEEEEHHCCCCCCHHHH
RYQQLKNRLLAEGLFDPQRKRSLPIHPQTIAVVTSPTAAAWGDIQKTLKHRYPGLHVLFS
HHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEC
PATVQGEQAPESIVKAIARVEKDGRAEVLILSRGGGAVEELACFNDERVVRAVAECSIPV
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHCCCCE
VTGIGHQRDESLVDLVADVCVHTPTAAAEKVVPSLAELSNQHRQRIIALHQVLLHTQTSA
EECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ENQLQTLRNRLQNLRLDRHLQQEAQKLNWQRQRLLQLTMGRSQQAKQHLELLRQKLISLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
PKSVLQRGYAVVRQENGAIARSADELAVGNELFIQLAQGEVKAKVIEVEQRQ
HHHHHHHHHHEEEECCCCCCCCCHHHHCCHHHHEEECCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840