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The map label for this gene is rsbU [H]

Identifier: 17229250

GI number: 17229250

Start: 2111793

End: 2113184

Strand: Reverse

Name: rsbU [H]

Synonym: all1758

Alternate gene names: 17229250

Gene position: 2113184-2111793 (Counterclockwise)

Preceding gene: 17229251

Following gene: 17229249

Centisome position: 32.95

GC content: 45.19

Gene sequence:

>1392_bases
GTGCCTGTGCCTCCATTTTCCTCTCAACCCACGGACAACAATAATAGTGCTGCGACAGATGTCACACCAGTCGTAGCACT
CAAAGAACTTGTGTCACGATTGCACCGGGAACAGAACAAAATCCAAGATTTGCTGAGTTCTTTAGGATTTGCCCTGAGGA
GCTTCAATAATCTGAACCAGTTTTTGGAACTAATTCCTCTAATGGCAACAAGAGTGACGGATGCTGATGGTAGCGCGCTG
TTTCTCTACAAACCTAATGGCCAAGTCAGATTAGAACAATTACATTGGCAAGACAGCCGCCAACGCAAAAACATCCGCAA
AGCCTTAGAAACAGCTAGTAGCCAAATCACACTTTTACCTAACACTGCGCCTCTAGCTAACGCCACAGGAATGCTAGATG
ACCAGATGCACCGCTACCTGGGGCCAGATGTGCAAATCTTTGGTACGGCAATTTTAGTCAAGCATACAGAACGGGGATGG
TTGTATGTATTAAGCCGCGATCCTGAGTATAGTTGGACAGAAACTAGACAAAAGTTAGTGCGGTTAGTTGCAGACCAAAC
CGCAGTGGCGATTGAAAACGACGAACTGGCAGTAGAACTGAGGAAAAAAGAACGTCTAGACCAAGAATTAGAAATTGGTG
CAGAGATTCAAAGACGATTACTGCCACGTCAGTGTCCTCATATTCCTGGTGTTAGTCTAGCAGCACGCTGTAGACCGGCC
AATCGCGTTGGTGGAGATTATTATGATTTTATTCCCACGAATCAAAGCCAAATTCACACATACACCAAACTTGGTCAAGA
TTCGGGTCGTTGGGGTTTGGTGATTGGTGATGTCATGGGTAAGGGTGTTCCTGCGGGGTTAATTATGACCATGATGCGAG
GAATGCTACGGGGAGAAGTATTACACGGTAACTCTCCGGCGGGGATTTTGCAGAATCTCAACCGAGTTATGTATGCGGAT
TTGGAAAATTCTCACCGCTTCATCACGCTATTTTATTCTGAATATAATCCGCATAAACGAATTTTGTCCTATAGTAATGC
AGCACATAATCCCCCTTTGTGGTGGCACGCAGCTACAAAAAGTGTTACCCGCCTAGATACTCTGGGGATGTTAATTGGGC
TGGATGCTAATAGCCAATACGAAGACGGTCAGGCACAGCTAGAACCTGGTGATACAGTTATTTATTATACGGATGGTTTG
ACCGATGCGGCTGCGGCCAGTGGCGATCGCTTTGATGAAGAAAACTTTGTTACTGCTTTCAGTACGGCTTGTCGGTACTG
TAACGGCCCAGAAGAAATTGTCGATTACCTATTCGACCGAGTTCAGCAATTTATCGGTGCTGACAGACAAAATAATGATG
ATATGACTTTAGTGGTCTTACAGATCGAATAA

Upstream 100 bases:

>100_bases
CAAAAGCGCTAAACTTTAACCCAATATGGTTTAGCGATCGCCAAATAGAAAATTTATTAATTGTCAATCTAAAATTAACC
CCTTTCCAGTGCAATAACCT

Downstream 100 bases:

>100_bases
TTTATCGAGTATAAAAGGGACTGGGGATTGGGGATTGGGCGAAAATCTTGGAGTAAATTCTCCCCTTGCTCCCTGCCTCT
TTTCTTCCTATTAGGGTGAG

Product: hypothetical protein

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MPVPPFSSQPTDNNNSAATDVTPVVALKELVSRLHREQNKIQDLLSSLGFALRSFNNLNQFLELIPLMATRVTDADGSAL
FLYKPNGQVRLEQLHWQDSRQRKNIRKALETASSQITLLPNTAPLANATGMLDDQMHRYLGPDVQIFGTAILVKHTERGW
LYVLSRDPEYSWTETRQKLVRLVADQTAVAIENDELAVELRKKERLDQELEIGAEIQRRLLPRQCPHIPGVSLAARCRPA
NRVGGDYYDFIPTNQSQIHTYTKLGQDSGRWGLVIGDVMGKGVPAGLIMTMMRGMLRGEVLHGNSPAGILQNLNRVMYAD
LENSHRFITLFYSEYNPHKRILSYSNAAHNPPLWWHAATKSVTRLDTLGMLIGLDANSQYEDGQAQLEPGDTVIYYTDGL
TDAAAASGDRFDEENFVTAFSTACRYCNGPEEIVDYLFDRVQQFIGADRQNNDDMTLVVLQIE

Sequences:

>Translated_463_residues
MPVPPFSSQPTDNNNSAATDVTPVVALKELVSRLHREQNKIQDLLSSLGFALRSFNNLNQFLELIPLMATRVTDADGSAL
FLYKPNGQVRLEQLHWQDSRQRKNIRKALETASSQITLLPNTAPLANATGMLDDQMHRYLGPDVQIFGTAILVKHTERGW
LYVLSRDPEYSWTETRQKLVRLVADQTAVAIENDELAVELRKKERLDQELEIGAEIQRRLLPRQCPHIPGVSLAARCRPA
NRVGGDYYDFIPTNQSQIHTYTKLGQDSGRWGLVIGDVMGKGVPAGLIMTMMRGMLRGEVLHGNSPAGILQNLNRVMYAD
LENSHRFITLFYSEYNPHKRILSYSNAAHNPPLWWHAATKSVTRLDTLGMLIGLDANSQYEDGQAQLEPGDTVIYYTDGL
TDAAAASGDRFDEENFVTAFSTACRYCNGPEEIVDYLFDRVQQFIGADRQNNDDMTLVVLQIE
>Mature_462_residues
PVPPFSSQPTDNNNSAATDVTPVVALKELVSRLHREQNKIQDLLSSLGFALRSFNNLNQFLELIPLMATRVTDADGSALF
LYKPNGQVRLEQLHWQDSRQRKNIRKALETASSQITLLPNTAPLANATGMLDDQMHRYLGPDVQIFGTAILVKHTERGWL
YVLSRDPEYSWTETRQKLVRLVADQTAVAIENDELAVELRKKERLDQELEIGAEIQRRLLPRQCPHIPGVSLAARCRPAN
RVGGDYYDFIPTNQSQIHTYTKLGQDSGRWGLVIGDVMGKGVPAGLIMTMMRGMLRGEVLHGNSPAGILQNLNRVMYADL
ENSHRFITLFYSEYNPHKRILSYSNAAHNPPLWWHAATKSVTRLDTLGMLIGLDANSQYEDGQAQLEPGDTVIYYTDGLT
DAAAASGDRFDEENFVTAFSTACRYCNGPEEIVDYLFDRVQQFIGADRQNNDDMTLVVLQIE

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 52035; Mature: 51903

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVPPFSSQPTDNNNSAATDVTPVVALKELVSRLHREQNKIQDLLSSLGFALRSFNNLNQ
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLELIPLMATRVTDADGSALFLYKPNGQVRLEQLHWQDSRQRKNIRKALETASSQITLLP
HHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEECC
NTAPLANATGMLDDQMHRYLGPDVQIFGTAILVKHTERGWLYVLSRDPEYSWTETRQKLV
CCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHH
RLVADQTAVAIENDELAVELRKKERLDQELEIGAEIQRRLLPRQCPHIPGVSLAARCRPA
HHHHCCCEEEEECCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCC
NRVGGDYYDFIPTNQSQIHTYTKLGQDSGRWGLVIGDVMGKGVPAGLIMTMMRGMLRGEV
HHCCCCEEECCCCCHHHHHHHHHCCCCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHCCCE
LHGNSPAGILQNLNRVMYADLENSHRFITLFYSEYNPHKRILSYSNAAHNPPLWWHAATK
EECCCCHHHHHHHHHHEEEECCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCEEEEHHHH
SVTRLDTLGMLIGLDANSQYEDGQAQLEPGDTVIYYTDGLTDAAAASGDRFDEENFVTAF
HHHHHHHHHHEEECCCCCCCCCCCCEECCCCEEEEEECCCCHHHHCCCCCCCCCHHHHHH
STACRYCNGPEEIVDYLFDRVQQFIGADRQNNDDMTLVVLQIE
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEC
>Mature Secondary Structure 
PVPPFSSQPTDNNNSAATDVTPVVALKELVSRLHREQNKIQDLLSSLGFALRSFNNLNQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLELIPLMATRVTDADGSALFLYKPNGQVRLEQLHWQDSRQRKNIRKALETASSQITLLP
HHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEECC
NTAPLANATGMLDDQMHRYLGPDVQIFGTAILVKHTERGWLYVLSRDPEYSWTETRQKLV
CCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHH
RLVADQTAVAIENDELAVELRKKERLDQELEIGAEIQRRLLPRQCPHIPGVSLAARCRPA
HHHHCCCEEEEECCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCC
NRVGGDYYDFIPTNQSQIHTYTKLGQDSGRWGLVIGDVMGKGVPAGLIMTMMRGMLRGEV
HHCCCCEEECCCCCHHHHHHHHHCCCCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHCCCE
LHGNSPAGILQNLNRVMYADLENSHRFITLFYSEYNPHKRILSYSNAAHNPPLWWHAATK
EECCCCHHHHHHHHHHEEEECCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCEEEEHHHH
SVTRLDTLGMLIGLDANSQYEDGQAQLEPGDTVIYYTDGLTDAAAASGDRFDEENFVTAF
HHHHHHHHHHEEECCCCCCCCCCCCEECCCCEEEEEECCCCHHHHCCCCCCCCCHHHHHH
STACRYCNGPEEIVDYLFDRVQQFIGADRQNNDDMTLVVLQIE
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]