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The map label for this gene is maiA [H]

Identifier: 17229237

GI number: 17229237

Start: 2099928

End: 2100587

Strand: Reverse

Name: maiA [H]

Synonym: all1745

Alternate gene names: 17229237

Gene position: 2100587-2099928 (Counterclockwise)

Preceding gene: 17229239

Following gene: 17229235

Centisome position: 32.75

GC content: 44.09

Gene sequence:

>660_bases
GTGATGCTGAAGTTTTACTACAATCCCATCTCTGTTAATGCTCGTCGAGTTTGGGTAGCCTTACTAGAAAAACAAATCCC
TTTTGAACCATTGTTGTTGAATCTCAATGGTGATCAGTTTCAAGAGGAATTCACGGCAATTAATCCCCTCCAGCGCGTAC
CTGTGATAGTGGATAATGGCTTACGGGTGATAGAATCTTTGGCAATTTTGGATTATCTAGAGACAAAATATCCTACTCCC
TCGTTGATTCCTAGTGAGCCTGGAGCGATCGCTACAGTTCGTATGGTAGAAATGATCACAATCAGCGAGCTTCAGCCTGC
TACAGTCATCTTGACTCGGCCATTAGTAGAATTAGATACCGATGCCAAAAAACTCGTATCGGCTCAAGAGGCAGTAGCGA
AAATTTTACAGTTTTATGAAACTCTTTTAGGTGAACAGATTTACTTTGCAGGCAAAGATTTCACACTGGCAGAAGTGGTT
GCAGGTACGTTGATTCCTTCTCTCCCCCTTTTTGGGTTCTCTTTAGATGATTACCCCCGTCTGCTAGCCTGGGCGGAACG
ACTAGAAGAGCGAGAAAGTTGGCAACAAACCACCCCAGATTTTGCATCCATCGCCGCCGCTATCCCTAACATCAAGGCAA
TTCTAGAACGCCGTTTTTAA

Upstream 100 bases:

>100_bases
AGGGAAAACTTGTAATTTTATTGTGCTAGATTTTTCAGTATTTTGTACAATCACTTAACGAAAGGATATAATCCCTGAGC
GTAGTTTATAACTTAGGGTT

Downstream 100 bases:

>100_bases
GAATGGGGATTAGGGAGTCTAGACAATATGGTTCTGCCTCAAGGGAAAATCTACAACGAAACATAAAGATATAGCTAGGG
ATTAGGGACTGGGTACTGGG

Product: glutathione transferase

Products: NA

Alternate protein names: MAAI [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MMLKFYYNPISVNARRVWVALLEKQIPFEPLLLNLNGDQFQEEFTAINPLQRVPVIVDNGLRVIESLAILDYLETKYPTP
SLIPSEPGAIATVRMVEMITISELQPATVILTRPLVELDTDAKKLVSAQEAVAKILQFYETLLGEQIYFAGKDFTLAEVV
AGTLIPSLPLFGFSLDDYPRLLAWAERLEERESWQQTTPDFASIAAAIPNIKAILERRF

Sequences:

>Translated_219_residues
MMLKFYYNPISVNARRVWVALLEKQIPFEPLLLNLNGDQFQEEFTAINPLQRVPVIVDNGLRVIESLAILDYLETKYPTP
SLIPSEPGAIATVRMVEMITISELQPATVILTRPLVELDTDAKKLVSAQEAVAKILQFYETLLGEQIYFAGKDFTLAEVV
AGTLIPSLPLFGFSLDDYPRLLAWAERLEERESWQQTTPDFASIAAAIPNIKAILERRF
>Mature_219_residues
MMLKFYYNPISVNARRVWVALLEKQIPFEPLLLNLNGDQFQEEFTAINPLQRVPVIVDNGLRVIESLAILDYLETKYPTP
SLIPSEPGAIATVRMVEMITISELQPATVILTRPLVELDTDAKKLVSAQEAVAKILQFYETLLGEQIYFAGKDFTLAEVV
AGTLIPSLPLFGFSLDDYPRLLAWAERLEERESWQQTTPDFASIAAAIPNIKAILERRF

Specific function: Forms An Equimolar Complex With The RNA Polymerase Holoenzyme (Rnap) But Not With The Core Enzyme. It Is Synthesized Predominantly When Cells Are Exposed To Amino Acid Starvation, At Which Time It Accounts For Over 50% Of The Total Protein Synthesized. It

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI22202624, Length=189, Percent_Identity=30.6878306878307, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4504187, Length=198, Percent_Identity=30.3030303030303, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI124249394, Length=198, Percent_Identity=30.3030303030303, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1789624, Length=196, Percent_Identity=26.530612244898, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17510461, Length=194, Percent_Identity=27.8350515463918, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17556142, Length=191, Percent_Identity=26.7015706806283, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551302, Length=187, Percent_Identity=28.8770053475936, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17864598, Length=218, Percent_Identity=27.5229357798165, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45549270, Length=223, Percent_Identity=26.457399103139, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21355857, Length=201, Percent_Identity=25.8706467661692, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17864592, Length=223, Percent_Identity=25.1121076233184, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17933730, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI85725204, Length=203, Percent_Identity=29.5566502463054, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17737923, Length=203, Percent_Identity=29.5566502463054, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45553325, Length=189, Percent_Identity=27.5132275132275, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24645375, Length=189, Percent_Identity=27.5132275132275, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21355859, Length=189, Percent_Identity=27.5132275132275, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28571670, Length=200, Percent_Identity=25.5, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI17864594, Length=188, Percent_Identity=26.063829787234, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646251, Length=209, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19922526, Length=191, Percent_Identity=28.7958115183246, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24654979, Length=192, Percent_Identity=29.6875, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI20130115, Length=195, Percent_Identity=28.2051282051282, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1982 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR005955
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =5.2.1.2 [H]

Molecular weight: Translated: 24725; Mature: 24725

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLKFYYNPISVNARRVWVALLEKQIPFEPLLLNLNGDQFQEEFTAINPLQRVPVIVDNG
CEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCHHHHCCEEECCH
LRVIESLAILDYLETKYPTPSLIPSEPGAIATVRMVEMITISELQPATVILTRPLVELDT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHCCC
DAKKLVSAQEAVAKILQFYETLLGEQIYFAGKDFTLAEVVAGTLIPSLPLFGFSLDDYPR
CHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHH
LLAWAERLEERESWQQTTPDFASIAAAIPNIKAILERRF
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MMLKFYYNPISVNARRVWVALLEKQIPFEPLLLNLNGDQFQEEFTAINPLQRVPVIVDNG
CEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCHHHHCCEEECCH
LRVIESLAILDYLETKYPTPSLIPSEPGAIATVRMVEMITISELQPATVILTRPLVELDT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHCCC
DAKKLVSAQEAVAKILQFYETLLGEQIYFAGKDFTLAEVVAGTLIPSLPLFGFSLDDYPR
CHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHH
LLAWAERLEERESWQQTTPDFASIAAAIPNIKAILERRF
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]