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The map label for this gene is steT [H]

Identifier: 17229011

GI number: 17229011

Start: 1779326

End: 1780693

Strand: Direct

Name: steT [H]

Synonym: alr1519

Alternate gene names: 17229011

Gene position: 1779326-1780693 (Clockwise)

Preceding gene: 17229007

Following gene: 17229012

Centisome position: 27.74

GC content: 44.88

Gene sequence:

>1368_bases
GTGAGTAGACATACAGATTACAGTTCGCTAGAGCAAATACAGACGACTGGTGCAGATGCACCCAAGCCATTATTAACACT
ATCAGACGCAGTTGCTCTAATTGTCGGGATTGTCATTGGTGTAGGTATTTTTCAAACCCCTGCGCTGGTAGCTAGTCAAG
CTGGAAGTGATACTGCGGTACTGTTGTTTTGGTTAGCTGGTGGCATAGTCTCTATTATTGGTGCATTGTGCTACGCAGAG
TTGGCGACAACTTATCCTAATGTTGGTGGAGCCTACTATTATCTAAAGCGAGCATTTGGCCAAAATACTGCCTTTTTATT
TGCCTGGGCAAGGTTGACAGTGATTCAGACTGGTTCTATTGCCTTGGCGGCATTTGTTTTTGGTGATTATGCGTCTGAGA
TTTGGCGGCTGGGTACATTTTCATCATCAATGTATGCCGCAGTGATAATTGCTTTATTAACGATATTAAACATACTGGGT
TTACACCAGGGAAAATGGACACAAAATTTACTGACGGCGGCGCAAGTCTTGGGTTTATTGCTGGTAGTCCTTTTTGGACT
AGCTAGCACTGCTAATAGTGCTAATAGTGCTGTATCGCCGGAACCTTCATCCTCAGGTAGTTGGGGACTAGCAATGGTGT
TTGTACTGCTGTCATACGGTGGTTGGAATGAAGCCGCGTATATTTCGGCAGAGATAAAAAACAGGCAAAGAAATATCTTG
CGATCGCTCATGTGGAGTATTGGTATTATCACAGCAATTTACCTGCTGATCAACCTAGCTTTTTTGCGAGGCTTAGGATT
AGCAAATATGGCAAACTCATCAGCAGTTGCCGCAGACTTGATGCGTGCTGTCTGGGGTACGCCAGGTGTTGTATTTATCA
GCCTCTTGATTGCGATTTGTGCTTTAGGGACAATCAATGCCTCCATTTTTACTGGCGCACGTACTAACTATGCCTTAGGG
CAAGATTTTAACCTGTTTGGCTTCATGGGAAGTTGGAGACAAATCCCCAGTACTCCTGCGACTGCCTTATTAGTCCAAGG
TGCGATCGCTCTTGCCTTGGTTGTATTAGGCACATTCACCCGCAAGGGATTTGAAACAATGGTGGATTACACCGCACCCG
TGTTTTGGTTCTTCTTTCTACTTTCTGGCATATCACTATTAATATTGCGCCAGAAAGAACCACACATACCGCGTCCGTTT
CGTGTGCCTTTTTATCCTATTACCCCATTACTCTTTTGTGCTGTTTGTGGCTACTTACTATACTCCAGCGTAGTTTATAC
AAACGTGGGCGCTGTTGTCGGTGTTTTGGTGGTGATAGCAGGTGTCCCGTTATTGTTCTGGAATCGCTACCGCCAAGGTA
AGGCTTAG

Upstream 100 bases:

>100_bases
ATAACTACGCAATATTATTCATGGCCAATTAAAGAGTTTAATACCCATCTGCCTCCTGACTTTCCTTTTGATTCAGTGCA
AACAACTATGAGGAAGCAAT

Downstream 100 bases:

>100_bases
AAATTCAAAATTAACTAGGAGAATAATCATGAAGTTGCAAAAGATTTTACTATCTATTGTTACAGGTGTTAGTGTTGTGA
GCCTGGGATTAGCTGGCTGC

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSRHTDYSSLEQIQTTGADAPKPLLTLSDAVALIVGIVIGVGIFQTPALVASQAGSDTAVLLFWLAGGIVSIIGALCYAE
LATTYPNVGGAYYYLKRAFGQNTAFLFAWARLTVIQTGSIALAAFVFGDYASEIWRLGTFSSSMYAAVIIALLTILNILG
LHQGKWTQNLLTAAQVLGLLLVVLFGLASTANSANSAVSPEPSSSGSWGLAMVFVLLSYGGWNEAAYISAEIKNRQRNIL
RSLMWSIGIITAIYLLINLAFLRGLGLANMANSSAVAADLMRAVWGTPGVVFISLLIAICALGTINASIFTGARTNYALG
QDFNLFGFMGSWRQIPSTPATALLVQGAIALALVVLGTFTRKGFETMVDYTAPVFWFFFLLSGISLLILRQKEPHIPRPF
RVPFYPITPLLFCAVCGYLLYSSVVYTNVGAVVGVLVVIAGVPLLFWNRYRQGKA

Sequences:

>Translated_455_residues
MSRHTDYSSLEQIQTTGADAPKPLLTLSDAVALIVGIVIGVGIFQTPALVASQAGSDTAVLLFWLAGGIVSIIGALCYAE
LATTYPNVGGAYYYLKRAFGQNTAFLFAWARLTVIQTGSIALAAFVFGDYASEIWRLGTFSSSMYAAVIIALLTILNILG
LHQGKWTQNLLTAAQVLGLLLVVLFGLASTANSANSAVSPEPSSSGSWGLAMVFVLLSYGGWNEAAYISAEIKNRQRNIL
RSLMWSIGIITAIYLLINLAFLRGLGLANMANSSAVAADLMRAVWGTPGVVFISLLIAICALGTINASIFTGARTNYALG
QDFNLFGFMGSWRQIPSTPATALLVQGAIALALVVLGTFTRKGFETMVDYTAPVFWFFFLLSGISLLILRQKEPHIPRPF
RVPFYPITPLLFCAVCGYLLYSSVVYTNVGAVVGVLVVIAGVPLLFWNRYRQGKA
>Mature_454_residues
SRHTDYSSLEQIQTTGADAPKPLLTLSDAVALIVGIVIGVGIFQTPALVASQAGSDTAVLLFWLAGGIVSIIGALCYAEL
ATTYPNVGGAYYYLKRAFGQNTAFLFAWARLTVIQTGSIALAAFVFGDYASEIWRLGTFSSSMYAAVIIALLTILNILGL
HQGKWTQNLLTAAQVLGLLLVVLFGLASTANSANSAVSPEPSSSGSWGLAMVFVLLSYGGWNEAAYISAEIKNRQRNILR
SLMWSIGIITAIYLLINLAFLRGLGLANMANSSAVAADLMRAVWGTPGVVFISLLIAICALGTINASIFTGARTNYALGQ
DFNLFGFMGSWRQIPSTPATALLVQGAIALALVVLGTFTRKGFETMVDYTAPVFWFFFLLSGISLLILRQKEPHIPRPFR
VPFYPITPLLFCAVCGYLLYSSVVYTNVGAVVGVLVVIAGVPLLFWNRYRQGKA

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI186910308, Length=434, Percent_Identity=32.4884792626728, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI186910306, Length=434, Percent_Identity=32.4884792626728, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI186910304, Length=434, Percent_Identity=32.4884792626728, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI115648063, Length=460, Percent_Identity=30.8695652173913, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI115648022, Length=460, Percent_Identity=30.8695652173913, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI187423910, Length=434, Percent_Identity=29.2626728110599, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI7657591, Length=434, Percent_Identity=29.2626728110599, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI33286428, Length=450, Percent_Identity=28.8888888888889, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI71979932, Length=440, Percent_Identity=29.7727272727273, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI7657683, Length=416, Percent_Identity=24.5192307692308, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI9790235, Length=424, Percent_Identity=25.7075471698113, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI33286430, Length=239, Percent_Identity=27.1966527196653, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI71999149, Length=393, Percent_Identity=25.4452926208651, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI258614003, Length=373, Percent_Identity=25.7372654155496, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI258614005, Length=373, Percent_Identity=25.7372654155496, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI258645169, Length=375, Percent_Identity=25.6, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87082250, Length=433, Percent_Identity=25.635103926097, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786694, Length=335, Percent_Identity=27.4626865671642, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17540018, Length=454, Percent_Identity=28.1938325991189, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71995388, Length=453, Percent_Identity=28.6975717439294, Blast_Score=148, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI71995382, Length=453, Percent_Identity=28.6975717439294, Blast_Score=148, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI32566699, Length=473, Percent_Identity=28.7526427061311, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71993915, Length=452, Percent_Identity=27.8761061946903, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI71982612, Length=393, Percent_Identity=27.735368956743, Blast_Score=138, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI71982608, Length=393, Percent_Identity=27.735368956743, Blast_Score=138, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17568033, Length=457, Percent_Identity=25.601750547046, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI193208714, Length=425, Percent_Identity=25.6470588235294, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI32566695, Length=425, Percent_Identity=25.6470588235294, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71982623, Length=263, Percent_Identity=27.7566539923954, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71990446, Length=453, Percent_Identity=22.7373068432671, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17532491, Length=366, Percent_Identity=24.8633879781421, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321751, Length=383, Percent_Identity=22.4543080939948, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321492, Length=340, Percent_Identity=25, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21357367, Length=434, Percent_Identity=27.8801843317972, Blast_Score=171, Evalue=8e-43,
Organism=Drosophila melanogaster, GI45550968, Length=440, Percent_Identity=29.0909090909091, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI19921172, Length=440, Percent_Identity=29.0909090909091, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24641993, Length=386, Percent_Identity=30.0518134715026, Blast_Score=161, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24641995, Length=386, Percent_Identity=30.0518134715026, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI221331183, Length=441, Percent_Identity=27.437641723356, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI17647653, Length=441, Percent_Identity=27.437641723356, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24664379, Length=441, Percent_Identity=27.437641723356, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24651635, Length=436, Percent_Identity=27.2935779816514, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24651633, Length=436, Percent_Identity=27.2935779816514, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24668806, Length=404, Percent_Identity=23.2673267326733, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21356285, Length=404, Percent_Identity=23.2673267326733, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24668802, Length=404, Percent_Identity=23.2673267326733, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48764; Mature: 48633

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRHTDYSSLEQIQTTGADAPKPLLTLSDAVALIVGIVIGVGIFQTPALVASQAGSDTAV
CCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHH
LLFWLAGGIVSIIGALCYAELATTYPNVGGAYYYLKRAFGQNTAFLFAWARLTVIQTGSI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHEECCCH
ALAAFVFGDYASEIWRLGTFSSSMYAAVIIALLTILNILGLHQGKWTQNLLTAAQVLGLL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LVVLFGLASTANSANSAVSPEPSSSGSWGLAMVFVLLSYGGWNEAAYISAEIKNRQRNIL
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHH
RSLMWSIGIITAIYLLINLAFLRGLGLANMANSSAVAADLMRAVWGTPGVVFISLLIAIC
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
ALGTINASIFTGARTNYALGQDFNLFGFMGSWRQIPSTPATALLVQGAIALALVVLGTFT
HHHHCCHHHEECCCCCCCCCCCCCHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
RKGFETMVDYTAPVFWFFFLLSGISLLILRQKEPHIPRPFRVPFYPITPLLFCAVCGYLL
HHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
YSSVVYTNVGAVVGVLVVIAGVPLLFWNRYRQGKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SRHTDYSSLEQIQTTGADAPKPLLTLSDAVALIVGIVIGVGIFQTPALVASQAGSDTAV
CCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHH
LLFWLAGGIVSIIGALCYAELATTYPNVGGAYYYLKRAFGQNTAFLFAWARLTVIQTGSI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHEECCCH
ALAAFVFGDYASEIWRLGTFSSSMYAAVIIALLTILNILGLHQGKWTQNLLTAAQVLGLL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LVVLFGLASTANSANSAVSPEPSSSGSWGLAMVFVLLSYGGWNEAAYISAEIKNRQRNIL
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHH
RSLMWSIGIITAIYLLINLAFLRGLGLANMANSSAVAADLMRAVWGTPGVVFISLLIAIC
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
ALGTINASIFTGARTNYALGQDFNLFGFMGSWRQIPSTPATALLVQGAIALALVVLGTFT
HHHHCCHHHEECCCCCCCCCCCCCHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
RKGFETMVDYTAPVFWFFFLLSGISLLILRQKEPHIPRPFRVPFYPITPLLFCAVCGYLL
HHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
YSSVVYTNVGAVVGVLVVIAGVPLLFWNRYRQGKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]