Click here to switch to the map view.

The map label for this gene is arlR [H]

Identifier: 17228269

GI number: 17228269

Start: 897280

End: 897666

Strand: Direct

Name: arlR [H]

Synonym: alr0774

Alternate gene names: 17228269

Gene position: 897280-897666 (Clockwise)

Preceding gene: 17228268

Following gene: 17228271

Centisome position: 13.99

GC content: 40.83

Gene sequence:

>387_bases
ATGACGCACATCTTACTGGTTGAAGATGAAGTCAAACTAGCACGATTTCTGGAATTGGAACTAAACTATCAAGGGTATCA
GGTTAGTGTCGCCTACGATGGATTAACTGCAATGATTGCAGCCCGGCAATTGCAGCTAGATTTGATAATTTTAGATGGGA
AAATTCCTGGTTTATCGGCGTGGGAAATTTGCCACCGCTTGGGGAATAGTGCCAAAAATATACCGATAATATTGTTAACG
GCTAAAGATGAAGTCACCTCTCGCATTGCTGGTTTAGATGCTAGTACTGCCGATTATGTAGTCAAACCCTTTAATATTGA
GGAATTATTAGCTAAAGTCTGCACTCATTTACGAAAAACGCAACAAGCAGATGCAGCCGATAAGTAG

Upstream 100 bases:

>100_bases
CTATATGCGACGACCTACGGTCGGTCGAAGACCATCGCCTAAATGCCTACAGTATCGGTATCTTACAATTGTTACCTTAC
CTTTTTACTTTTGCTCGATC

Downstream 100 bases:

>100_bases
GGAGGAAGTTAAAGAGACTTAATTGCTTGATAACGTCCAAGGGCAATTAAAGGAAAGTACTGTTGATAGTAGTGATACTT
CAAGTAAAAGTGACAAGGGA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MTHILLVEDEVKLARFLELELNYQGYQVSVAYDGLTAMIAARQLQLDLIILDGKIPGLSAWEICHRLGNSAKNIPIILLT
AKDEVTSRIAGLDASTADYVVKPFNIEELLAKVCTHLRKTQQADAADK

Sequences:

>Translated_128_residues
MTHILLVEDEVKLARFLELELNYQGYQVSVAYDGLTAMIAARQLQLDLIILDGKIPGLSAWEICHRLGNSAKNIPIILLT
AKDEVTSRIAGLDASTADYVVKPFNIEELLAKVCTHLRKTQQADAADK
>Mature_127_residues
THILLVEDEVKLARFLELELNYQGYQVSVAYDGLTAMIAARQLQLDLIILDGKIPGLSAWEICHRLGNSAKNIPIILLTA
KDEVTSRIAGLDASTADYVVKPFNIEELLAKVCTHLRKTQQADAADK

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=116, Percent_Identity=40.5172413793103, Blast_Score=89, Evalue=8e-20,
Organism=Escherichia coli, GI1786784, Length=116, Percent_Identity=41.3793103448276, Blast_Score=87, Evalue=3e-19,
Organism=Escherichia coli, GI1789809, Length=117, Percent_Identity=41.025641025641, Blast_Score=84, Evalue=4e-18,
Organism=Escherichia coli, GI1790860, Length=119, Percent_Identity=36.9747899159664, Blast_Score=80, Evalue=4e-17,
Organism=Escherichia coli, GI1786911, Length=127, Percent_Identity=37.007874015748, Blast_Score=74, Evalue=2e-15,
Organism=Escherichia coli, GI1788394, Length=129, Percent_Identity=34.8837209302326, Blast_Score=73, Evalue=5e-15,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=33.0508474576271, Blast_Score=71, Evalue=3e-14,
Organism=Escherichia coli, GI1790552, Length=120, Percent_Identity=36.6666666666667, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=29.3577981651376, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1790863, Length=118, Percent_Identity=32.2033898305085, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1789402, Length=119, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=8e-12,
Organism=Escherichia coli, GI1787375, Length=117, Percent_Identity=29.9145299145299, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 14163; Mature: 14031

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHILLVEDEVKLARFLELELNYQGYQVSVAYDGLTAMIAARQLQLDLIILDGKIPGLSA
CCEEEEECCCHHEEEEEEEEECCCCEEEEEEECCHHHHHHHHHEEEEEEEECCCCCCCHH
WEICHRLGNSAKNIPIILLTAKDEVTSRIAGLDASTADYVVKPFNIEELLAKVCTHLRKT
HHHHHHHCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHH
QQADAADK
HCCCCCCC
>Mature Secondary Structure 
THILLVEDEVKLARFLELELNYQGYQVSVAYDGLTAMIAARQLQLDLIILDGKIPGLSA
CEEEEECCCHHEEEEEEEEECCCCEEEEEEECCHHHHHHHHHEEEEEEEECCCCCCCHH
WEICHRLGNSAKNIPIILLTAKDEVTSRIAGLDASTADYVVKPFNIEELLAKVCTHLRKT
HHHHHHHCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHH
QQADAADK
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA