Click here to switch to the map view.

The map label for this gene is xisC

Identifier: 17228173

GI number: 17228173

Start: 785653

End: 787149

Strand: Direct

Name: xisC

Synonym: alr0677

Alternate gene names: 17228173

Gene position: 785653-787149 (Clockwise)

Preceding gene: 17228172

Following gene: 17228175

Centisome position: 12.25

GC content: 35.2

Gene sequence:

>1497_bases
ATGAGCGGACAAAATCAGGGGAATTGCGAGGAGACATATTCCACATCTACACATGAATATGCAAATGCAGACTCAACCGA
CTGGTTCGCAGATATGTTTGCAGATTTTGAGCCGCAGAACACCACAGACGGCAGCTATAGGGGAACAATGGCGAAAATAA
AAGCAACGGAATTACAGTATCAAGCAGTTTTTGAACAGAAGTTAGTCGAAGCCAATACTAATTTAAAAAGGGAGAGAATA
AGAGTTAGCATTAAACAGACTGGTAATTCTCTCCAATTACGAGCTACCCTACCCTTAAAACCAGGGGATGGTAGTTTAGG
TAAGACAAAAAAACAGTATGATTTGTCTCTAGGGATACCAGCAAATTTAGAAGGACTGAAAACTGCAATTGAAGAAAGTT
ACGAGTTGGGTAAATTAATCGCTCGTCATACTTTCGAGTGGAATGAGAAGTATTTAGGAATTAAATCTAGAGAGAAGCAA
GAAATAAAAACTATTGGGGAATTATTAGATAAATTTGAGGAAAAATATTATCAAACCCGTCAGAAAACTATAACCAGTCA
AAATACTTTTCCTAACTATATATCTGTAATTAAAAGAAACTTTCCTCTCACCCATTTAGCCACAAAAGAAAATTTTGAGG
AAATTATTAATTCAGTTCAGGGGAATAAAAAAAATGAACTAATTGCCGTAACTTCTGTTTTTATTAAAACCTTTAATTTA
GGATTTCAACTCGATGTTAAACGTGATAATGTCACCCCTGCTCATCGAGAAATACCTGAAGATGACAAAATAATATATTC
TTTTGACCTCTTTGAAAAATTCGCCCTCAATCGCAAAAATACAAATATTAGTGATGAAATCGACACCTGGGAAATGTGGC
GTTGGGTATATGGAATGTTGGCGACATTTGGGTTAAGACCAAGGGAACTATTTGTACAACCAGATATTAATTGGTGGATG
TCTCCCCAAAATCTAGACCATACTTGGAAAGTCAATAAAAATACAAAAACTGGATATCGAGAAGTTATTCCTTTTGTTCC
TGAATGGATAGAATTATTTGATTTAAAAAATCCCAAACCATTAAAGATTTTAGAAAAAAAGGTGACAAAAATTGCATCTG
TACAAAATATTAATTGGATGCGGAGAGATATATCCAGATGGTTTAGAAAAGTGGGAATTGAGTTTCAACCCTACGATTTG
CGTCATGCTTGTGCAATTCGAGCGCATCTTCAAGGAATACCTATTAAAGCAGCAGCAGATAATTTAGGTCATACTGTTGA
TGAACATACAAAAACCTATCAAAGATGGTTTGGTATTGAAAATAGGAAAAAAGCCTTTGGTGAGGTAATTAGTCAAAAGT
CATTAATTGAGTTGCAGAAGAATGAAATATTGGCGTTACGGATGGAGAATGAAAGGTTAAGGTTGGAGGTGGAAAAGTTG
AAATTTTCGACAACTAAAAATCCAGAGGACTGTGAACAGCTTTACCATCAAGGTTAA

Upstream 100 bases:

>100_bases
TTGAAAATGTTACTGAGTAACGTTTTAGTAAGGCAATTTTGCTCGGTAAGAACATTTTATTTTCACCATTTCAGTTTATA
AATAAGGGAATATTTAGGGA

Downstream 100 bases:

>100_bases
GAATGTGCGTATAAATCATGGTGATTTTGACATCCTTGTGTCCGAGTAATTCCTGAAAAGTGCGAATGTCATAAGAATTT
TGCAGTAAATGGGTAGCTCG

Product: hupL element site-specific recombinase

Products: NA

Alternate protein names: HupL element site-specific recombinase

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MSGQNQGNCEETYSTSTHEYANADSTDWFADMFADFEPQNTTDGSYRGTMAKIKATELQYQAVFEQKLVEANTNLKRERI
RVSIKQTGNSLQLRATLPLKPGDGSLGKTKKQYDLSLGIPANLEGLKTAIEESYELGKLIARHTFEWNEKYLGIKSREKQ
EIKTIGELLDKFEEKYYQTRQKTITSQNTFPNYISVIKRNFPLTHLATKENFEEIINSVQGNKKNELIAVTSVFIKTFNL
GFQLDVKRDNVTPAHREIPEDDKIIYSFDLFEKFALNRKNTNISDEIDTWEMWRWVYGMLATFGLRPRELFVQPDINWWM
SPQNLDHTWKVNKNTKTGYREVIPFVPEWIELFDLKNPKPLKILEKKVTKIASVQNINWMRRDISRWFRKVGIEFQPYDL
RHACAIRAHLQGIPIKAAADNLGHTVDEHTKTYQRWFGIENRKKAFGEVISQKSLIELQKNEILALRMENERLRLEVEKL
KFSTTKNPEDCEQLYHQG

Sequences:

>Translated_498_residues
MSGQNQGNCEETYSTSTHEYANADSTDWFADMFADFEPQNTTDGSYRGTMAKIKATELQYQAVFEQKLVEANTNLKRERI
RVSIKQTGNSLQLRATLPLKPGDGSLGKTKKQYDLSLGIPANLEGLKTAIEESYELGKLIARHTFEWNEKYLGIKSREKQ
EIKTIGELLDKFEEKYYQTRQKTITSQNTFPNYISVIKRNFPLTHLATKENFEEIINSVQGNKKNELIAVTSVFIKTFNL
GFQLDVKRDNVTPAHREIPEDDKIIYSFDLFEKFALNRKNTNISDEIDTWEMWRWVYGMLATFGLRPRELFVQPDINWWM
SPQNLDHTWKVNKNTKTGYREVIPFVPEWIELFDLKNPKPLKILEKKVTKIASVQNINWMRRDISRWFRKVGIEFQPYDL
RHACAIRAHLQGIPIKAAADNLGHTVDEHTKTYQRWFGIENRKKAFGEVISQKSLIELQKNEILALRMENERLRLEVEKL
KFSTTKNPEDCEQLYHQG
>Mature_497_residues
SGQNQGNCEETYSTSTHEYANADSTDWFADMFADFEPQNTTDGSYRGTMAKIKATELQYQAVFEQKLVEANTNLKRERIR
VSIKQTGNSLQLRATLPLKPGDGSLGKTKKQYDLSLGIPANLEGLKTAIEESYELGKLIARHTFEWNEKYLGIKSREKQE
IKTIGELLDKFEEKYYQTRQKTITSQNTFPNYISVIKRNFPLTHLATKENFEEIINSVQGNKKNELIAVTSVFIKTFNLG
FQLDVKRDNVTPAHREIPEDDKIIYSFDLFEKFALNRKNTNISDEIDTWEMWRWVYGMLATFGLRPRELFVQPDINWWMS
PQNLDHTWKVNKNTKTGYREVIPFVPEWIELFDLKNPKPLKILEKKVTKIASVQNINWMRRDISRWFRKVGIEFQPYDLR
HACAIRAHLQGIPIKAAADNLGHTVDEHTKTYQRWFGIENRKKAFGEVISQKSLIELQKNEILALRMENERLRLEVEKLK
FSTTKNPEDCEQLYHQG

Specific function: Essential for DNA excision. Site specific recombinase necessary for the excision of the 10.5 kb hupL element during heterocyst differentiation

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xisA/xisC recombinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XISC_NOSS1 (Q44217)

Other databases:

- EMBL:   U08014
- EMBL:   BA000019
- PIR:   AD1891
- RefSeq:   NP_484721.1
- ProteinModelPortal:   Q44217
- SMR:   Q44217
- STRING:   Q44217
- GeneID:   1104273
- GenomeReviews:   BA000019_GR
- KEGG:   ana:alr0677
- NMPDR:   fig|103690.1.peg.987
- eggNOG:   COG0582
- HOGENOM:   HBG581461
- OMA:   THEYANA
- ProtClustDB:   CLSK2518496
- BioCyc:   NSP103690:ALR0677-MONOMER
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz

EC number: NA

Molecular weight: Translated: 58196; Mature: 58065

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQNQGNCEETYSTSTHEYANADSTDWFADMFADFEPQNTTDGSYRGTMAKIKATELQY
CCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHH
QAVFEQKLVEANTNLKRERIRVSIKQTGNSLQLRATLPLKPGDGSLGKTKKQYDLSLGIP
HHHHHHHHHHHCCCCCHHHHEEEEEECCCEEEEEEEECCCCCCCCCCCCCHHEEEEECCC
ANLEGLKTAIEESYELGKLIARHTFEWNEKYLGIKSREKQEIKTIGELLDKFEEKYYQTR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QKTITSQNTFPNYISVIKRNFPLTHLATKENFEEIINSVQGNKKNELIAVTSVFIKTFNL
HHHHCCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCC
GFQLDVKRDNVTPAHREIPEDDKIIYSFDLFEKFALNRKNTNISDEIDTWEMWRWVYGML
CEEEEEECCCCCCHHHCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
ATFGLRPRELFVQPDINWWMSPQNLDHTWKVNKNTKTGYREVIPFVPEWIELFDLKNPKP
HHHCCCCHHEEECCCCCEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCH
LKILEKKVTKIASVQNINWMRRDISRWFRKVGIEFQPYDLRHACAIRAHLQGIPIKAAAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHH
NLGHTVDEHTKTYQRWFGIENRKKAFGEVISQKSLIELQKNEILALRMENERLRLEVEKL
HHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEHE
KFSTTKNPEDCEQLYHQG
EECCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SGQNQGNCEETYSTSTHEYANADSTDWFADMFADFEPQNTTDGSYRGTMAKIKATELQY
CCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHH
QAVFEQKLVEANTNLKRERIRVSIKQTGNSLQLRATLPLKPGDGSLGKTKKQYDLSLGIP
HHHHHHHHHHHCCCCCHHHHEEEEEECCCEEEEEEEECCCCCCCCCCCCCHHEEEEECCC
ANLEGLKTAIEESYELGKLIARHTFEWNEKYLGIKSREKQEIKTIGELLDKFEEKYYQTR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QKTITSQNTFPNYISVIKRNFPLTHLATKENFEEIINSVQGNKKNELIAVTSVFIKTFNL
HHHHCCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCC
GFQLDVKRDNVTPAHREIPEDDKIIYSFDLFEKFALNRKNTNISDEIDTWEMWRWVYGML
CEEEEEECCCCCCHHHCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
ATFGLRPRELFVQPDINWWMSPQNLDHTWKVNKNTKTGYREVIPFVPEWIELFDLKNPKP
HHHCCCCHHEEECCCCCEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCH
LKILEKKVTKIASVQNINWMRRDISRWFRKVGIEFQPYDLRHACAIRAHLQGIPIKAAAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHH
NLGHTVDEHTKTYQRWFGIENRKKAFGEVISQKSLIELQKNEILALRMENERLRLEVEKL
HHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEHE
KFSTTKNPEDCEQLYHQG
EECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7846053; 11759840