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The map label for this gene is ydjE [H]

Identifier: 17228013

GI number: 17228013

Start: 609201

End: 610178

Strand: Direct

Name: ydjE [H]

Synonym: alr0517

Alternate gene names: 17228013

Gene position: 609201-610178 (Clockwise)

Preceding gene: 17228012

Following gene: 17228014

Centisome position: 9.5

GC content: 45.09

Gene sequence:

>978_bases
ATGAGTAATCCCCGTGTTTTGTGCCTCGGCGAAGTTCTATTCGATTGTTTAGCTGATCAATTAGGGCTAAAGCTGGAACA
GGTAAAGTCTTGGACTGCTTATCCAGGAGGAGCGCCAGCTAATGTGGCTTGTGCTTTAGTGAAGTTGGGAACTCCCGCCG
GATTTATTGGTGCTGTCGGTGAGGATGAGCCAGGAAATGTGCTGGTTAAGCTATTACAAGAAGTAGGTGTAGATACAACG
GGTGTACAACGTCATTCTACTGCCCCAACTAGGCAAGTCTATGTGGTCAGGGATCTAGCAGGCGATCGCACTTTCGCTGG
CTTCGGTCAGTATGATACATCTGAATTTGCTGATACGCATTTGCAAGCCAAGCAATTACCAGAGTCAGTGTTTCAAGAAG
CGGATTTCCTGATTTTGGGTACATTGGAATTAGCCTATCCCGACAGTGAAAAAGCTATTCACCGAGCTTTGGAACTGGCT
GAACAGTATGACCTGAAGATTGTGCTGGATGTTAACTGGCGGCCGGTATTTTGGCATGATGAAAATATTGCTAGGCAAAA
AATTCAGGAAATTTTCAAACGCGTTGATTTCCTCAAGCTTGCTAAAGAAGAAGCTGAATGGCTATTCGACACCTCTGATC
CAGGCGCTATTACTTACCGTTTAGGCTCTATTGAGGGGGTATTAGTAACTGATGGCGAAAACGGCTGTGGTTATTGCTTG
GGTGAGAATGAAGGTAAAATACCTGCTTTTGCTGTTTCTGTAGTAGATACCACGGGCGCAGGAGATAGCTTTCTGGCAGG
GTTTATCCATCAACTGAGTGAACATGGCATTCACAACTTGAATGATGCAGAGACAGCAAAACGCATTATTACTTATGCTA
GTGCTGTAGGGGCGTTGACTACTACTAAAGCAGGTGCGATCGCTTCTCAACCTACCGCGATGGAAGTGGAAACTTTTTTA
GCCTCCAATAAAATTTAG

Upstream 100 bases:

>100_bases
TTGTGCGGAGTGCGAATGCTAATAGATAAATATGAGATCACTAATCTAAAGCCAAAAAACTAAAATGGGATGAGCAATCC
CCGTGAAAAACTAAAATGAA

Downstream 100 bases:

>100_bases
TTGAACTACCCACACTGACCTATCGGGTCAGATGTGGGGCTTTTGTCGGTTCAAGCTAAAGTAGTAATAGTGATAGTTGT
AGAACTCAAGTTGGCTGCTC

Product: fructokinase

Products: ADP; D-fructose 6-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSNPRVLCLGEVLFDCLADQLGLKLEQVKSWTAYPGGAPANVACALVKLGTPAGFIGAVGEDEPGNVLVKLLQEVGVDTT
GVQRHSTAPTRQVYVVRDLAGDRTFAGFGQYDTSEFADTHLQAKQLPESVFQEADFLILGTLELAYPDSEKAIHRALELA
EQYDLKIVLDVNWRPVFWHDENIARQKIQEIFKRVDFLKLAKEEAEWLFDTSDPGAITYRLGSIEGVLVTDGENGCGYCL
GENEGKIPAFAVSVVDTTGAGDSFLAGFIHQLSEHGIHNLNDAETAKRIITYASAVGALTTTKAGAIASQPTAMEVETFL
ASNKI

Sequences:

>Translated_325_residues
MSNPRVLCLGEVLFDCLADQLGLKLEQVKSWTAYPGGAPANVACALVKLGTPAGFIGAVGEDEPGNVLVKLLQEVGVDTT
GVQRHSTAPTRQVYVVRDLAGDRTFAGFGQYDTSEFADTHLQAKQLPESVFQEADFLILGTLELAYPDSEKAIHRALELA
EQYDLKIVLDVNWRPVFWHDENIARQKIQEIFKRVDFLKLAKEEAEWLFDTSDPGAITYRLGSIEGVLVTDGENGCGYCL
GENEGKIPAFAVSVVDTTGAGDSFLAGFIHQLSEHGIHNLNDAETAKRIITYASAVGALTTTKAGAIASQPTAMEVETFL
ASNKI
>Mature_324_residues
SNPRVLCLGEVLFDCLADQLGLKLEQVKSWTAYPGGAPANVACALVKLGTPAGFIGAVGEDEPGNVLVKLLQEVGVDTTG
VQRHSTAPTRQVYVVRDLAGDRTFAGFGQYDTSEFADTHLQAKQLPESVFQEADFLILGTLELAYPDSEKAIHRALELAE
QYDLKIVLDVNWRPVFWHDENIARQKIQEIFKRVDFLKLAKEEAEWLFDTSDPGAITYRLGSIEGVLVTDGENGCGYCLG
ENEGKIPAFAVSVVDTTGAGDSFLAGFIHQLSEHGIHNLNDAETAKRIITYASAVGALTTTKAGAIASQPTAMEVETFLA
SNKI

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87082343, Length=325, Percent_Identity=28.9230769230769, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87082281, Length=247, Percent_Identity=27.5303643724696, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081971, Length=328, Percent_Identity=24.390243902439, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: 2.7.1.4

Molecular weight: Translated: 35177; Mature: 35046

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPRVLCLGEVLFDCLADQLGLKLEQVKSWTAYPGGAPANVACALVKLGTPAGFIGAVG
CCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHEEEEEECCCCCCEEECCC
EDEPGNVLVKLLQEVGVDTTGVQRHSTAPTRQVYVVRDLAGDRTFAGFGQYDTSEFADTH
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCCCCCCHHHHHHH
LQAKQLPESVFQEADFLILGTLELAYPDSEKAIHRALELAEQYDLKIVLDVNWRPVFWHD
HHHHHHHHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCEEEEEECCCEEEEECC
ENIARQKIQEIFKRVDFLKLAKEEAEWLFDTSDPGAITYRLGSIEGVLVTDGENGCGYCL
CHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEECCEEEEEEECCCCCCEEEE
GENEGKIPAFAVSVVDTTGAGDSFLAGFIHQLSEHGIHNLNDAETAKRIITYASAVGALT
CCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
TTKAGAIASQPTAMEVETFLASNKI
HCCCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SNPRVLCLGEVLFDCLADQLGLKLEQVKSWTAYPGGAPANVACALVKLGTPAGFIGAVG
CCCCEEEHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHEEEEEECCCCCCEEECCC
EDEPGNVLVKLLQEVGVDTTGVQRHSTAPTRQVYVVRDLAGDRTFAGFGQYDTSEFADTH
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCCCCCCHHHHHHH
LQAKQLPESVFQEADFLILGTLELAYPDSEKAIHRALELAEQYDLKIVLDVNWRPVFWHD
HHHHHHHHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCEEEEEECCCEEEEECC
ENIARQKIQEIFKRVDFLKLAKEEAEWLFDTSDPGAITYRLGSIEGVLVTDGENGCGYCL
CHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEECCEEEEEEECCCCCCEEEE
GENEGKIPAFAVSVVDTTGAGDSFLAGFIHQLSEHGIHNLNDAETAKRIITYASAVGALT
CCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
TTKAGAIASQPTAMEVETFLASNKI
HCCCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-fructose

Specific reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9455482; 9384377 [H]