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The map label for this gene is hsdR [H]

Identifier: 17228006

GI number: 17228006

Start: 603121

End: 605130

Strand: Direct

Name: hsdR [H]

Synonym: alr0510

Alternate gene names: 17228006

Gene position: 603121-605130 (Clockwise)

Preceding gene: 17228005

Following gene: 17228007

Centisome position: 9.4

GC content: 41.04

Gene sequence:

>2010_bases
GTGCTGTTTGTGGTCGATCGCGCTGACCTTGACTACCAAACCAGTAAGGAATTTAATTATTTTAGTCCTGAGTGTGTGGA
CACCACCGACAACACCGGACAACTGGTAACACAAATGGCTGGGGATAGTCGCCTGATTGTGACGACGATTCAAAAACTCA
ACCGGGCGATCAAATCCCCACGCCATGAAGCTGCAATGTCAGGCTTGAAGGATCAGCCCATTGTGTTTATCTTTGACGAG
TGTCACCGTTCCCAATTTGGCGAAACCCACAAAAATATCCTTAAATTCTTTACCCAAGCCCAAATGTTTGGCTTTACCGG
GACTCCCATCTTTGCTGATAACGCCACCAGCAACCAGCACGGTAAACGCACCACTAGGGACTTATTCCAGGAATGTTTGC
ATAAATATGTAATCACAAATGCGATCGCTGATGAAAATGTTTTAAAATTTTCCGTTGAGTATTGGGGCGGAATGAAACGC
AAAGACGGCACATTAATTACAGAACCAAAGAGCGATCGCTTTGAAACCCCTGAGCGAATTTCTGGAATTGTCGATTGGAT
TATTGCCAACCATCACCGTAAAACCCACGGCAAAAAATTCTCTGCTATGCTCTGCGTCAGTAATGTAGATACTCTAATTA
CTTATTACGAAATCTTTAAAAATCAACAGCAACAGGGATTACATAACCTGCGAATAATTACTATTTTTACCCCCAGCGAT
AACGAAGAAGACGAAGACGCAAACGGCTTAATTGGAGAACCGGATTTTAATATCAGCAACGATACGAGCAGCCGCAGCCA
TAGCCGCGACAAATTGAATGAATTTATCGCCGACTATAACCAAATGTATAAAACCCAGCATTCCGCTAAAGATGGTCAGG
CTTTTTATGCCTACTACAAAGACATCTCAAAACGGATGAAGGACAGAGATAGAGAAAACTTTCAGGACGCAGAACGCGCC
GATATTCTGTTAGTCGTGAATATGTTTATCACGGGTTTTGATGTGAAAAAACTCAATACCCTCTATGTCGATAAAAATCT
CAAGTACCACGGGTTAATTCAAGCCTACTCCCGGACAAATCGCATTTTAGGCGAACTGAAATCTCAGGGTAATATTGTTT
GCTTTCGCAATCTTAAGGAGAATACCGATCAAGCGGTTTCGCTATTTTCCGATCCCAACGCCAACGAACAAATTTTTATT
GAACCCTACGAATACTATATTGAGAAATTTAATCAAGGTGTGGAAGAACTGAGAGCGATCGCCACTATCCCTAATGATGT
GAATAAACTAATTAGTGAAGATGACCAAGTTAATTTCGTTAAAGCCTTTCGTAATCTGATCCGTTTACAGGATGTTAGTA
AATCATTTACTGAATTTAGCTTTTCTGACTTAAATCTGGATGAACAAACTTTTGAAGATTATAAAAGTAAATATCTGGAC
ATCTACGATAAAACGCGCTCGAAACCTGATGATGAAAAAGAATCTTTAGTTGAGGAAGTCGATTTTGAACTGGAATTAAT
CCACCGCGACGAAATCAATGTCACCTATATTCTCAAGCTGCTGGCGAACCTCCAGCGCGACATCAAGGATGATGCTACCC
AGGAAGATTACCAAAATCAAAAAGCCTCTATCCTTGAGCTAATTGGGAAAGAAGCTCAACTACGCAGCAAGCGGGATTTA
CTGGAGAAATTTATCGAACAGCGACTACCCACCCTTGAACCCCAAGAAAAACTGGAAACCGTCTTCCAAGACTTTTGGAC
TCAAGAACGTATTGAAGCAATTGAACAACTTTGTCTAGAGGAAAATCTCCAGGTTACAACTGTTAATCAAATGATTGCTG
ACTATAAATTCTCTGGGAAAGAACCATTAAGGGAAACCATGCTGAGTGCTTGTAACGAAAAACCCAAATTATTAGAGCGT
AAAAAAATTTTTGGGCGCGTTGTCGCAAAATTACTCGACATCATCAACAAATTTGATGACGCTCTTGGTGAGCTTGGGGA
GGAAGAATAA

Upstream 100 bases:

>100_bases
CGATAAAAACGGCTATATCTGGCACACTACCGGCTCAGGGAAAACCCTCACCAGCTTCAAAGCTGCCCAAATCCTCAAAG
AACTGCCCAAAGTCCATAAA

Downstream 100 bases:

>100_bases
GCTTGCTGTTGTGGCAAAGTTATGGGTAAGATTACAAAAAAGCCGCCACGGGGACGGCTTTCTTATATATGGGCAGTACC
AGACTCGAACTGATGACATC

Product: type I site-specific deoxyribonuclease

Products: NA

Alternate protein names: Type I restriction enzyme R protein [H]

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MLFVVDRADLDYQTSKEFNYFSPECVDTTDNTGQLVTQMAGDSRLIVTTIQKLNRAIKSPRHEAAMSGLKDQPIVFIFDE
CHRSQFGETHKNILKFFTQAQMFGFTGTPIFADNATSNQHGKRTTRDLFQECLHKYVITNAIADENVLKFSVEYWGGMKR
KDGTLITEPKSDRFETPERISGIVDWIIANHHRKTHGKKFSAMLCVSNVDTLITYYEIFKNQQQQGLHNLRIITIFTPSD
NEEDEDANGLIGEPDFNISNDTSSRSHSRDKLNEFIADYNQMYKTQHSAKDGQAFYAYYKDISKRMKDRDRENFQDAERA
DILLVVNMFITGFDVKKLNTLYVDKNLKYHGLIQAYSRTNRILGELKSQGNIVCFRNLKENTDQAVSLFSDPNANEQIFI
EPYEYYIEKFNQGVEELRAIATIPNDVNKLISEDDQVNFVKAFRNLIRLQDVSKSFTEFSFSDLNLDEQTFEDYKSKYLD
IYDKTRSKPDDEKESLVEEVDFELELIHRDEINVTYILKLLANLQRDIKDDATQEDYQNQKASILELIGKEAQLRSKRDL
LEKFIEQRLPTLEPQEKLETVFQDFWTQERIEAIEQLCLEENLQVTTVNQMIADYKFSGKEPLRETMLSACNEKPKLLER
KKIFGRVVAKLLDIINKFDDALGELGEEE

Sequences:

>Translated_669_residues
MLFVVDRADLDYQTSKEFNYFSPECVDTTDNTGQLVTQMAGDSRLIVTTIQKLNRAIKSPRHEAAMSGLKDQPIVFIFDE
CHRSQFGETHKNILKFFTQAQMFGFTGTPIFADNATSNQHGKRTTRDLFQECLHKYVITNAIADENVLKFSVEYWGGMKR
KDGTLITEPKSDRFETPERISGIVDWIIANHHRKTHGKKFSAMLCVSNVDTLITYYEIFKNQQQQGLHNLRIITIFTPSD
NEEDEDANGLIGEPDFNISNDTSSRSHSRDKLNEFIADYNQMYKTQHSAKDGQAFYAYYKDISKRMKDRDRENFQDAERA
DILLVVNMFITGFDVKKLNTLYVDKNLKYHGLIQAYSRTNRILGELKSQGNIVCFRNLKENTDQAVSLFSDPNANEQIFI
EPYEYYIEKFNQGVEELRAIATIPNDVNKLISEDDQVNFVKAFRNLIRLQDVSKSFTEFSFSDLNLDEQTFEDYKSKYLD
IYDKTRSKPDDEKESLVEEVDFELELIHRDEINVTYILKLLANLQRDIKDDATQEDYQNQKASILELIGKEAQLRSKRDL
LEKFIEQRLPTLEPQEKLETVFQDFWTQERIEAIEQLCLEENLQVTTVNQMIADYKFSGKEPLRETMLSACNEKPKLLER
KKIFGRVVAKLLDIINKFDDALGELGEEE
>Mature_669_residues
MLFVVDRADLDYQTSKEFNYFSPECVDTTDNTGQLVTQMAGDSRLIVTTIQKLNRAIKSPRHEAAMSGLKDQPIVFIFDE
CHRSQFGETHKNILKFFTQAQMFGFTGTPIFADNATSNQHGKRTTRDLFQECLHKYVITNAIADENVLKFSVEYWGGMKR
KDGTLITEPKSDRFETPERISGIVDWIIANHHRKTHGKKFSAMLCVSNVDTLITYYEIFKNQQQQGLHNLRIITIFTPSD
NEEDEDANGLIGEPDFNISNDTSSRSHSRDKLNEFIADYNQMYKTQHSAKDGQAFYAYYKDISKRMKDRDRENFQDAERA
DILLVVNMFITGFDVKKLNTLYVDKNLKYHGLIQAYSRTNRILGELKSQGNIVCFRNLKENTDQAVSLFSDPNANEQIFI
EPYEYYIEKFNQGVEELRAIATIPNDVNKLISEDDQVNFVKAFRNLIRLQDVSKSFTEFSFSDLNLDEQTFEDYKSKYLD
IYDKTRSKPDDEKESLVEEVDFELELIHRDEINVTYILKLLANLQRDIKDDATQEDYQNQKASILELIGKEAQLRSKRDL
LEKFIEQRLPTLEPQEKLETVFQDFWTQERIEAIEQLCLEENLQVTTVNQMIADYKFSGKEPLRETMLSACNEKPKLLER
KKIFGRVVAKLLDIINKFDDALGELGEEE

Specific function: Subunit R is required for both nuclease and ATPase activities, but not for modification [H]

COG id: COG0610

COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR014021
- InterPro:   IPR004473
- InterPro:   IPR006935
- InterPro:   IPR007409
- InterPro:   IPR022625 [H]

Pfam domain/function: PF12008 EcoR124_C; PF04313 HSDR_N; PF04851 ResIII [H]

EC number: =3.1.21.3 [H]

Molecular weight: Translated: 77777; Mature: 77777

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFVVDRADLDYQTSKEFNYFSPECVDTTDNTGQLVTQMAGDSRLIVTTIQKLNRAIKSP
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHCC
RHEAAMSGLKDQPIVFIFDECHRSQFGETHKNILKFFTQAQMFGFTGTPIFADNATSNQH
HHHHHHCCCCCCCEEEEECHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCC
GKRTTRDLFQECLHKYVITNAIADENVLKFSVEYWGGMKRKDGTLITEPKSDRFETPERI
CCHHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHCCCCCCCCEEEECCCCCCCCCHHHH
SGIVDWIIANHHRKTHGKKFSAMLCVSNVDTLITYYEIFKNQQQQGLHNLRIITIFTPSD
HHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
NEEDEDANGLIGEPDFNISNDTSSRSHSRDKLNEFIADYNQMYKTQHSAKDGQAFYAYYK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
DISKRMKDRDRENFQDAERADILLVVNMFITGFDVKKLNTLYVDKNLKYHGLIQAYSRTN
HHHHHHHHHHHHHHCHHHHHHHHEEEHHHHCCCCHHHCEEEEEECCCCHHHHHHHHHHHH
RILGELKSQGNIVCFRNLKENTDQAVSLFSDPNANEQIFIEPYEYYIEKFNQGVEELRAI
HHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHH
ATIPNDVNKLISEDDQVNFVKAFRNLIRLQDVSKSFTEFSFSDLNLDEQTFEDYKSKYLD
HCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
IYDKTRSKPDDEKESLVEEVDFELELIHRDEINVTYILKLLANLQRDIKDDATQEDYQNQ
HHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
KASILELIGKEAQLRSKRDLLEKFIEQRLPTLEPQEKLETVFQDFWTQERIEAIEQLCLE
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENLQVTTVNQMIADYKFSGKEPLRETMLSACNEKPKLLERKKIFGRVVAKLLDIINKFDD
CCCCEEEHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGELGEEE
HHHHCCCCC
>Mature Secondary Structure
MLFVVDRADLDYQTSKEFNYFSPECVDTTDNTGQLVTQMAGDSRLIVTTIQKLNRAIKSP
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHCC
RHEAAMSGLKDQPIVFIFDECHRSQFGETHKNILKFFTQAQMFGFTGTPIFADNATSNQH
HHHHHHCCCCCCCEEEEECHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCC
GKRTTRDLFQECLHKYVITNAIADENVLKFSVEYWGGMKRKDGTLITEPKSDRFETPERI
CCHHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHCCCCCCCCEEEECCCCCCCCCHHHH
SGIVDWIIANHHRKTHGKKFSAMLCVSNVDTLITYYEIFKNQQQQGLHNLRIITIFTPSD
HHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
NEEDEDANGLIGEPDFNISNDTSSRSHSRDKLNEFIADYNQMYKTQHSAKDGQAFYAYYK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
DISKRMKDRDRENFQDAERADILLVVNMFITGFDVKKLNTLYVDKNLKYHGLIQAYSRTN
HHHHHHHHHHHHHHCHHHHHHHHEEEHHHHCCCCHHHCEEEEEECCCCHHHHHHHHHHHH
RILGELKSQGNIVCFRNLKENTDQAVSLFSDPNANEQIFIEPYEYYIEKFNQGVEELRAI
HHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHH
ATIPNDVNKLISEDDQVNFVKAFRNLIRLQDVSKSFTEFSFSDLNLDEQTFEDYKSKYLD
HCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
IYDKTRSKPDDEKESLVEEVDFELELIHRDEINVTYILKLLANLQRDIKDDATQEDYQNQ
HHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
KASILELIGKEAQLRSKRDLLEKFIEQRLPTLEPQEKLETVFQDFWTQERIEAIEQLCLE
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENLQVTTVNQMIADYKFSGKEPLRETMLSACNEKPKLLERKKIFGRVVAKLLDIINKFDD
CCCCEEEHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGELGEEE
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA