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The map label for this gene is hsdR [H]

Identifier: 17228005

GI number: 17228005

Start: 602481

End: 603005

Strand: Direct

Name: hsdR [H]

Synonym: alr0509

Alternate gene names: 17228005

Gene position: 602481-603005 (Clockwise)

Preceding gene: 17228004

Following gene: 17228006

Centisome position: 9.39

GC content: 43.24

Gene sequence:

>525_bases
ATGGAACTCAGCCGCGACGATGGCACAACCTTTTACCTAGAATTTCTCAATATCGAACATTGGTGTCAAAATCAATATCA
AGTCACCAACCAAATCACCCAGCAAGGCAATTACAAAAACCGCTACGACGTAACCCTGCTGATTAATGGTTTACCCCTCG
TGCAAATTGAACTCAAACGCCGAGGACTGGAACTAAAAGAAGCCTTCAACCAAATCAACCGCTACCAACGCCATTCCTAC
GGCGCAGACATTGGACTATTTCAATATGTGCAAATATTCGTCATCTCCAACGGCGTAAATACCCGCTACTACGCCAACAA
CCGCAAACAAGAATATAAACAAACATTCTACTGGGCAGATGAAGAAAACAACCTGATCACCCAACTAGAAGACTTCGCCG
ATCGCTTTTTGGAAAAATGCCACGTTTCCAAAATGATCTGTAAATACATTGTTCTGCACGAATCTGACAAAGTGCTGATG
GTGTTGCGTCCCTACCAATTATTATGCGGTAGAAGCCATCATTGA

Upstream 100 bases:

>100_bases
ACATAACCACATCCAACTCAGCGATACCGAATTTAAAACCATCCTCAATCACCTGGATAAAGGTAACGTCTTTGACCGCG
CCAAACGCCTCCGCGATAAA

Downstream 100 bases:

>100_bases
GCGTGTCAAAAACACCGATAAAAACGGCTATATCTGGCACACTACCGGCTCAGGGAAAACCCTCACCAGCTTCAAAGCTG
CCCAAATCCTCAAAGAACTG

Product: type I site-specific deoxyribonuclease

Products: NA

Alternate protein names: Type I restriction enzyme R protein [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MELSRDDGTTFYLEFLNIEHWCQNQYQVTNQITQQGNYKNRYDVTLLINGLPLVQIELKRRGLELKEAFNQINRYQRHSY
GADIGLFQYVQIFVISNGVNTRYYANNRKQEYKQTFYWADEENNLITQLEDFADRFLEKCHVSKMICKYIVLHESDKVLM
VLRPYQLLCGRSHH

Sequences:

>Translated_174_residues
MELSRDDGTTFYLEFLNIEHWCQNQYQVTNQITQQGNYKNRYDVTLLINGLPLVQIELKRRGLELKEAFNQINRYQRHSY
GADIGLFQYVQIFVISNGVNTRYYANNRKQEYKQTFYWADEENNLITQLEDFADRFLEKCHVSKMICKYIVLHESDKVLM
VLRPYQLLCGRSHH
>Mature_174_residues
MELSRDDGTTFYLEFLNIEHWCQNQYQVTNQITQQGNYKNRYDVTLLINGLPLVQIELKRRGLELKEAFNQINRYQRHSY
GADIGLFQYVQIFVISNGVNTRYYANNRKQEYKQTFYWADEENNLITQLEDFADRFLEKCHVSKMICKYIVLHESDKVLM
VLRPYQLLCGRSHH

Specific function: Subunit R is required for both nuclease and ATPase activities, but not for modification [H]

COG id: COG0610

COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR014021
- InterPro:   IPR004473
- InterPro:   IPR006935
- InterPro:   IPR007409
- InterPro:   IPR022625 [H]

Pfam domain/function: PF12008 EcoR124_C; PF04313 HSDR_N; PF04851 ResIII [H]

EC number: =3.1.21.3 [H]

Molecular weight: Translated: 20903; Mature: 20903

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSRDDGTTFYLEFLNIEHWCQNQYQVTNQITQQGNYKNRYDVTLLINGLPLVQIELKR
CCCCCCCCCEEEEEEECHHHHHCHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEHH
RGLELKEAFNQINRYQRHSYGADIGLFQYVQIFVISNGVNTRYYANNRKQEYKQTFYWAD
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCCCEEEECCHHHHHHHHEEEEC
EENNLITQLEDFADRFLEKCHVSKMICKYIVLHESDKVLMVLRPYQLLCGRSHH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCHHHHCCCCCC
>Mature Secondary Structure
MELSRDDGTTFYLEFLNIEHWCQNQYQVTNQITQQGNYKNRYDVTLLINGLPLVQIELKR
CCCCCCCCCEEEEEEECHHHHHCHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEHH
RGLELKEAFNQINRYQRHSYGADIGLFQYVQIFVISNGVNTRYYANNRKQEYKQTFYWAD
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCCCEEEECCHHHHHHHHEEEEC
EENNLITQLEDFADRFLEKCHVSKMICKYIVLHESDKVLMVLRPYQLLCGRSHH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA