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The map label for this gene is murG [H]

Identifier: 17227973

GI number: 17227973

Start: 567782

End: 568567

Strand: Direct

Name: murG [H]

Synonym: alr0477

Alternate gene names: 17227973

Gene position: 567782-568567 (Clockwise)

Preceding gene: 17227970

Following gene: 17227976

Centisome position: 8.85

GC content: 48.09

Gene sequence:

>786_bases
GTGACTACAGGTGGATATATCGCCGGGCCAGCAGTGATTGCGGCGCGTTCTCTGGGTTTACCTGTAATTTTTCATGAATC
TAACGCCTTACCTGGCAAAGTAACCCGCTTTTTTGGCCCTTGGTGTAGTGTAGTCGCCTTAGGATTTGACGTGGCTACCA
AGTATCTACCCCGCGCTACAAGTGTTTGTGTGGGTACTCCAGTGCGATCGCAATTCTTAAATCTAGGTAATAATTCGCAA
CTAGATTTAGCCATTCCTGGAGATGTCCCTGTAATTGTGGTGTTTGGTGGTAGCCAAGGCGCGGTGGCGGTAAATCAGTT
GGTGCGTCAAGCGGCTCCAGCTTGGTTTGAGGCTGGGGCTTACGTGGTACATTTGACAGGCGATCGCGATCCCGATGTTG
ATAGTCTCAAGCATCCCCAATATATAGAATTACCCTTCTACGACAATATGGCCGCCTTGCTGCAACGGGCTAATTTAGCA
ATTAGCCGTTCTGGTGCTGGTAGCTTAACAGAATTGACAGTATGTGGCACACCGGCAATTTTGATTCCCTACCCCTTTGC
GGCGGAAGACCATCAATCTTACAACGCCGAGGTATTTACCAAAGCTGGCGCAGCGTTAACCTTTAAGCAATCTGATTTGA
CAGCAGAGTTATTGCAAACTCAAGTTTTAAATTTATTACAATCCCCCACAGAGTTAGCCAAAATGGGGGAAAATGCCAAG
GCGATCGCTGTTCCCGATAGCGCTGATAAGTTGGCGACTCTAGTACGGGAAGTTGTGGAGAGATGA

Upstream 100 bases:

>100_bases
GCAAGGCTTGGGAATTTCATCTTTAGTCATATTAGGTAAACTGATCGGTTCAATCCTGAAAGTCCGCCGACTGTTGAAAC
AAGGTAATTTTCAAGGAGTC

Downstream 100 bases:

>100_bases
ATCAATTCAAAATTCAAAATTCAAAATACCCTACGGGTTCGCGTAGTGTCCTCGTTCGCGTTAGCGTCTCCGTTCGCGCA
GCGTCTCCGACAGGAGAAGG

Product: phospho-N-acetylmuramoyl-pentapeptide-transferas e

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTTGGYIAGPAVIAARSLGLPVIFHESNALPGKVTRFFGPWCSVVALGFDVATKYLPRATSVCVGTPVRSQFLNLGNNSQ
LDLAIPGDVPVIVVFGGSQGAVAVNQLVRQAAPAWFEAGAYVVHLTGDRDPDVDSLKHPQYIELPFYDNMAALLQRANLA
ISRSGAGSLTELTVCGTPAILIPYPFAAEDHQSYNAEVFTKAGAALTFKQSDLTAELLQTQVLNLLQSPTELAKMGENAK
AIAVPDSADKLATLVREVVER

Sequences:

>Translated_261_residues
MTTGGYIAGPAVIAARSLGLPVIFHESNALPGKVTRFFGPWCSVVALGFDVATKYLPRATSVCVGTPVRSQFLNLGNNSQ
LDLAIPGDVPVIVVFGGSQGAVAVNQLVRQAAPAWFEAGAYVVHLTGDRDPDVDSLKHPQYIELPFYDNMAALLQRANLA
ISRSGAGSLTELTVCGTPAILIPYPFAAEDHQSYNAEVFTKAGAALTFKQSDLTAELLQTQVLNLLQSPTELAKMGENAK
AIAVPDSADKLATLVREVVER
>Mature_260_residues
TTGGYIAGPAVIAARSLGLPVIFHESNALPGKVTRFFGPWCSVVALGFDVATKYLPRATSVCVGTPVRSQFLNLGNNSQL
DLAIPGDVPVIVVFGGSQGAVAVNQLVRQAAPAWFEAGAYVVHLTGDRDPDVDSLKHPQYIELPFYDNMAALLQRANLAI
SRSGAGSLTELTVCGTPAILIPYPFAAEDHQSYNAEVFTKAGAALTFKQSDLTAELLQTQVLNLLQSPTELAKMGENAKA
IAVPDSADKLATLVREVVER

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=264, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 27665; Mature: 27534

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGGYIAGPAVIAARSLGLPVIFHESNALPGKVTRFFGPWCSVVALGFDVATKYLPRAT
CCCCCEECCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SVCVGTPVRSQFLNLGNNSQLDLAIPGDVPVIVVFGGSQGAVAVNQLVRQAAPAWFEAGA
CEEECCCHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCE
YVVHLTGDRDPDVDSLKHPQYIELPFYDNMAALLQRANLAISRSGAGSLTELTVCGTPAI
EEEEEECCCCCCHHHCCCCCEEECCCCCCHHHHHHHHCCEEECCCCCCCEEEEECCCCEE
LIPYPFAAEDHQSYNAEVFTKAGAALTFKQSDLTAELLQTQVLNLLQSPTELAKMGENAK
EEECCCCCCCCCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHCCCCCE
AIAVPDSADKLATLVREVVER
EEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTGGYIAGPAVIAARSLGLPVIFHESNALPGKVTRFFGPWCSVVALGFDVATKYLPRAT
CCCCEECCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SVCVGTPVRSQFLNLGNNSQLDLAIPGDVPVIVVFGGSQGAVAVNQLVRQAAPAWFEAGA
CEEECCCHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCE
YVVHLTGDRDPDVDSLKHPQYIELPFYDNMAALLQRANLAISRSGAGSLTELTVCGTPAI
EEEEEECCCCCCHHHCCCCCEEECCCCCCHHHHHHHHCCEEECCCCCCCEEEEECCCCEE
LIPYPFAAEDHQSYNAEVFTKAGAALTFKQSDLTAELLQTQVLNLLQSPTELAKMGENAK
EEECCCCCCCCCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHCCCCCE
AIAVPDSADKLATLVREVVER
EEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA