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The map label for this gene is kch [H]

Identifier: 17227936

GI number: 17227936

Start: 519998

End: 521683

Strand: Direct

Name: kch [H]

Synonym: alr0440

Alternate gene names: 17227936

Gene position: 519998-521683 (Clockwise)

Preceding gene: 17227932

Following gene: 17227938

Centisome position: 8.11

GC content: 44.31

Gene sequence:

>1686_bases
ATGAAACCTCGAATTATTGTTTGTGGCTTAGGACGAACTGGATATAAAATCTTCCGTTTGCTGAGACAGCAGGGTGCGTT
TGTAGTAGGTATTCATCACAAACCCATCCCTGGCGAAGCTGGGGGAGATGTAATTATTGGCAATTTACAAACAGCTGCTA
CCCTAGCAGCAGCAGGGATTCATCAAGCACAAACTTTGGTGATTGCTAGCTCGGATGATGCTGTAAATTTGTCAATTATG
ATGCAGGCAAGGGTGCTGAATCCGCATATTCGGATTATTAACCGCTTTTACAATATTAATTTAGGCGATCGCCTAGATCA
AACTCTGCCAGAACACCTGAGTATGAGTGTGATTGGATTAGCCGCACCGTTATTTACTTTCGCTGCTTTGGGAAATCAAG
CAATTGGGCAGATCAAGTTATATGAGCAGACTTGGCCTGTCCAAGAAGAATATATTGATGAAAATCATCCCTGGCTTGGT
CGTAAGTTAAGTGAGCTGTGGGAGTGTCCGACACGGATGCCAATTTATTACTTACCTGTGGAAGGGGAGATGAGTTTGGT
ATCGGCGGTACTGTCTGGACAACATTTAAGAATAGGCGATCGCTTAATCGTGGGTATCCAACCCCGTGTCCGTTCTACTA
GACGATCCTTAATCAAAAAATGCCTGAAAGTTCTCACTAGTTTGCGGCAATTTCAACAACATGGACAATCAATAATTGTA
GGGGCGATCGTTTTACTGGCGATCGTTATGATTGCCACCCTCACCTATATGTCTACTGAATTGAGCTTATCTATGGTTGA
TGCGCTCTATTTTTCTGTAGGTATGATTACTGGTGCAGGTGGTAATGACAAGGTAGCAGAAAATGCTCCTAACAGTATCA
AATTATTCACTGTGGTTATGATGCTGGTTGGCGCTGTGGTGATTGGTATTTGGTATGCCATGATCACAGATTTTATTCTG
GGTACACGCTTCAAGCAATTTTGGGATGCAGCCCGGATTCCCCAGCGTCATCACTATATTGTCTGTGGTTTAAGCGGTGT
TGGTAGCAAAATTGTTCAGCAACTCCACACCAGTGGTTATGATGTGGTAGTGATTGAAACTGACTCCAACAATAAATACG
TCAACTCTGTACGTGGGTTAGGTATTCCCGTAATTCAAGGCGATGCCAGTTTCCGTACCACCCTCAAAACCAGCAATATA
AACTCTGCGTCCGCCGTGCTGGCTGTAACTAATAATGATGCTACTAACCTAGAGATTGCCCTGAAAGCTAAAGGTTTAGC
CCCGAAAATTCCCGTAATTGTCCACTATGCCGACCCTGATTTTGCAGGTATAGCACAACAAGTATTTGACTTTGAGGCGG
TATTAAGTTCAGCAGAATTGGCAGCGCCGGCCTTTGCGGCGGCGGCTTTGGGCGGACGCATCCTTGGTAACGGCATCACA
GCAGATAAACTTTGGGTAGCATTTGCCACTTTAATTACACCGTCACATCCTTTTTGTGGTCATGTGGTTAAAGATATAGC
CATGTCGGCTGAGTTCGTGCCTTTATACGTAGAAGCTAATGGTCAAAGGGTTCACGGCTGGAACTTATTAGCAACATACC
TGAGCGAAGGTGATGTTTTATATTTAACAATGCCAGCTAATCAGCTATATAAATTGTGGCGCGACGAACGGGCGTGTAAT
GCCTAG

Upstream 100 bases:

>100_bases
ATAACGTGTTTTCAGTTACAGTTATGCCAGATGCAATTAAGCCACAATGTTGATTAATCAATAGAAGTGCAGCCCTACCT
ATAAACGATGCTGCTGTCAC

Downstream 100 bases:

>100_bases
TTTGTGGGATTGGGGAAGGTGGGACACTGTTCCTTCTACCAGTACCCAGTCCCTAATCCCTAAACCTACCTCACTTCCAC
AACAGCAATCACTTTTTCGT

Product: hypothetical protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MKPRIIVCGLGRTGYKIFRLLRQQGAFVVGIHHKPIPGEAGGDVIIGNLQTAATLAAAGIHQAQTLVIASSDDAVNLSIM
MQARVLNPHIRIINRFYNINLGDRLDQTLPEHLSMSVIGLAAPLFTFAALGNQAIGQIKLYEQTWPVQEEYIDENHPWLG
RKLSELWECPTRMPIYYLPVEGEMSLVSAVLSGQHLRIGDRLIVGIQPRVRSTRRSLIKKCLKVLTSLRQFQQHGQSIIV
GAIVLLAIVMIATLTYMSTELSLSMVDALYFSVGMITGAGGNDKVAENAPNSIKLFTVVMMLVGAVVIGIWYAMITDFIL
GTRFKQFWDAARIPQRHHYIVCGLSGVGSKIVQQLHTSGYDVVVIETDSNNKYVNSVRGLGIPVIQGDASFRTTLKTSNI
NSASAVLAVTNNDATNLEIALKAKGLAPKIPVIVHYADPDFAGIAQQVFDFEAVLSSAELAAPAFAAAALGGRILGNGIT
ADKLWVAFATLITPSHPFCGHVVKDIAMSAEFVPLYVEANGQRVHGWNLLATYLSEGDVLYLTMPANQLYKLWRDERACN
A

Sequences:

>Translated_561_residues
MKPRIIVCGLGRTGYKIFRLLRQQGAFVVGIHHKPIPGEAGGDVIIGNLQTAATLAAAGIHQAQTLVIASSDDAVNLSIM
MQARVLNPHIRIINRFYNINLGDRLDQTLPEHLSMSVIGLAAPLFTFAALGNQAIGQIKLYEQTWPVQEEYIDENHPWLG
RKLSELWECPTRMPIYYLPVEGEMSLVSAVLSGQHLRIGDRLIVGIQPRVRSTRRSLIKKCLKVLTSLRQFQQHGQSIIV
GAIVLLAIVMIATLTYMSTELSLSMVDALYFSVGMITGAGGNDKVAENAPNSIKLFTVVMMLVGAVVIGIWYAMITDFIL
GTRFKQFWDAARIPQRHHYIVCGLSGVGSKIVQQLHTSGYDVVVIETDSNNKYVNSVRGLGIPVIQGDASFRTTLKTSNI
NSASAVLAVTNNDATNLEIALKAKGLAPKIPVIVHYADPDFAGIAQQVFDFEAVLSSAELAAPAFAAAALGGRILGNGIT
ADKLWVAFATLITPSHPFCGHVVKDIAMSAEFVPLYVEANGQRVHGWNLLATYLSEGDVLYLTMPANQLYKLWRDERACN
A
>Mature_561_residues
MKPRIIVCGLGRTGYKIFRLLRQQGAFVVGIHHKPIPGEAGGDVIIGNLQTAATLAAAGIHQAQTLVIASSDDAVNLSIM
MQARVLNPHIRIINRFYNINLGDRLDQTLPEHLSMSVIGLAAPLFTFAALGNQAIGQIKLYEQTWPVQEEYIDENHPWLG
RKLSELWECPTRMPIYYLPVEGEMSLVSAVLSGQHLRIGDRLIVGIQPRVRSTRRSLIKKCLKVLTSLRQFQQHGQSIIV
GAIVLLAIVMIATLTYMSTELSLSMVDALYFSVGMITGAGGNDKVAENAPNSIKLFTVVMMLVGAVVIGIWYAMITDFIL
GTRFKQFWDAARIPQRHHYIVCGLSGVGSKIVQQLHTSGYDVVVIETDSNNKYVNSVRGLGIPVIQGDASFRTTLKTSNI
NSASAVLAVTNNDATNLEIALKAKGLAPKIPVIVHYADPDFAGIAQQVFDFEAVLSSAELAAPAFAAAALGGRILGNGIT
ADKLWVAFATLITPSHPFCGHVVKDIAMSAEFVPLYVEANGQRVHGWNLLATYLSEGDVLYLTMPANQLYKLWRDERACN
A

Specific function: May play a role in the defense against osmotic shock [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787503, Length=233, Percent_Identity=24.8927038626609, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 61153; Mature: 61153

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPRIIVCGLGRTGYKIFRLLRQQGAFVVGIHHKPIPGEAGGDVIIGNLQTAATLAAAGI
CCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHCC
HQAQTLVIASSDDAVNLSIMMQARVLNPHIRIINRFYNINLGDRLDQTLPEHLSMSVIGL
CCEEEEEEECCCCCEEEEEEEEEHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AAPLFTFAALGNQAIGQIKLYEQTWPVQEEYIDENHPWLGRKLSELWECPTRMPIYYLPV
HHHHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEC
EGEMSLVSAVLSGQHLRIGDRLIVGIQPRVRSTRRSLIKKCLKVLTSLRQFQQHGQSIIV
CCCHHHHHHHHCCCEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
GAIVLLAIVMIATLTYMSTELSLSMVDALYFSVGMITGAGGNDKVAENAPNSIKLFTVVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHH
MLVGAVVIGIWYAMITDFILGTRFKQFWDAARIPQRHHYIVCGLSGVGSKIVQQLHTSGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHCCCC
DVVVIETDSNNKYVNSVRGLGIPVIQGDASFRTTLKTSNINSASAVLAVTNNDATNLEIA
EEEEEEECCCCCHHHHHCCCCCEEEECCCCEEEEEEECCCCCCEEEEEEECCCCCCEEEE
LKAKGLAPKIPVIVHYADPDFAGIAQQVFDFEAVLSSAELAAPAFAAAALGGRILGNGIT
EEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEECCCCC
ADKLWVAFATLITPSHPFCGHVVKDIAMSAEFVPLYVEANGQRVHGWNLLATYLSEGDVL
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEECHHHHHHHHCCCCEE
YLTMPANQLYKLWRDERACNA
EEEECHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKPRIIVCGLGRTGYKIFRLLRQQGAFVVGIHHKPIPGEAGGDVIIGNLQTAATLAAAGI
CCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHCC
HQAQTLVIASSDDAVNLSIMMQARVLNPHIRIINRFYNINLGDRLDQTLPEHLSMSVIGL
CCEEEEEEECCCCCEEEEEEEEEHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AAPLFTFAALGNQAIGQIKLYEQTWPVQEEYIDENHPWLGRKLSELWECPTRMPIYYLPV
HHHHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEC
EGEMSLVSAVLSGQHLRIGDRLIVGIQPRVRSTRRSLIKKCLKVLTSLRQFQQHGQSIIV
CCCHHHHHHHHCCCEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
GAIVLLAIVMIATLTYMSTELSLSMVDALYFSVGMITGAGGNDKVAENAPNSIKLFTVVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHH
MLVGAVVIGIWYAMITDFILGTRFKQFWDAARIPQRHHYIVCGLSGVGSKIVQQLHTSGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHCCCC
DVVVIETDSNNKYVNSVRGLGIPVIQGDASFRTTLKTSNINSASAVLAVTNNDATNLEIA
EEEEEEECCCCCHHHHHCCCCCEEEECCCCEEEEEEECCCCCCEEEEEEECCCCCCEEEE
LKAKGLAPKIPVIVHYADPDFAGIAQQVFDFEAVLSSAELAAPAFAAAALGGRILGNGIT
EEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEECCCCC
ADKLWVAFATLITPSHPFCGHVVKDIAMSAEFVPLYVEANGQRVHGWNLLATYLSEGDVL
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEECHHHHHHHHCCCCEE
YLTMPANQLYKLWRDERACNA
EEEECHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8170937; 9097039; 9278503 [H]