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The map label for this gene is sds [H]

Identifier: 17227592

GI number: 17227592

Start: 101711

End: 102682

Strand: Direct

Name: sds [H]

Synonym: alr0096

Alternate gene names: 17227592

Gene position: 101711-102682 (Clockwise)

Preceding gene: 17227590

Following gene: 17227594

Centisome position: 1.59

GC content: 44.86

Gene sequence:

>972_bases
ATGACCCCAGCCACCTCCCTGTTTACCCCTGTGGAAGCAGACCTGCGAATACTAGCAGATAACCTGAAACAGCTAGTTGG
AAATCGCCACCCCATTTTGTTTGCAGCAGCCGAGCATCTATTCGGAGCTGGGGGAAAGCGTATAAGACCAGCGATCGTGC
TGCTGATATCACGAGCAACAATGTTAGACCAAGGCATTACACCGCGTCACCGCCGCCTAGCCGAGATTACAGAAATGATT
CACACGGCCAGCTTAGTCCATGACGACGTGGTAGACGAATCTGAAGTGCGACGAGGTGTCCCCACCGTTCATAGTTTGTT
TGGCAATCGAATTGCAATTCTAGCAGGAGATTTTTTATTTGCTCAATCTTCCTGGTATTTAGCCAACTTGGATAATTTGC
AAGTGGTGAAACTACTCTCAGAAGTCATTATGGATTTGGCTACTGGGGAAATTCAGCAGGGACTAAACCGCTTTGACGCG
AGTATTTCCATTGAGACTTATATCGAGAAGAGCTATTACAAAACAGCATCTTTAGTTGCTAACAGTTCTAAAGCAGCTGG
TTTATTGAGTGAAGTGTCTCCAGAAACTGCCGAACATCTTTACGCCTATGGTCGTCATTTAGGCATAGCATTTCAAATTG
TTGATGACATTTTAGATTTTACTAGCACTACGGATACCCTTGGTAAACCAGTAGGGTCGGATCTAAAAAGCGGTAATCTC
ACAGCGCCGGTTTTATTTGCTCTAGCAGAAAAACCATACCTAGAGGTGTTGATTGAACGAGAGTTTGCCCAAGAAGGAGA
TTTAGAGCAAGCACTAGAACTCATACAAGATAGTCAAGGCATACAGCAGTCAAGAGAGTTAGCTGCTCACCACACCAAGT
TAGCAATTGAGCATTTGGCAACTCTGCCACCCTCAGAATCTCACCAAGCACTGATCAAGATAGCTGAATATGCAATAAGC
CGATTGTATTAG

Upstream 100 bases:

>100_bases
TGAGAATATCCCAAGCAAAACCTTGCACAGGCACAGGCTTATCTTAAAATGAGTATAGGATATGTAAACTTTCGTAACCA
AAGTCAGAGTCCGCCAATCC

Downstream 100 bases:

>100_bases
CCGGATTTAAAAATTTCGATTTTAAATGAGCGTTTTCTGACATTTACAATTTTGGATGTGGGGTGTATTTAAAAAGTCCC
ACATCCAAAATTTTTTTAGG

Product: solanesyl diphosphate synthase

Products: trans-polyisoprenyln-PP; pyrophosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MTPATSLFTPVEADLRILADNLKQLVGNRHPILFAAAEHLFGAGGKRIRPAIVLLISRATMLDQGITPRHRRLAEITEMI
HTASLVHDDVVDESEVRRGVPTVHSLFGNRIAILAGDFLFAQSSWYLANLDNLQVVKLLSEVIMDLATGEIQQGLNRFDA
SISIETYIEKSYYKTASLVANSSKAAGLLSEVSPETAEHLYAYGRHLGIAFQIVDDILDFTSTTDTLGKPVGSDLKSGNL
TAPVLFALAEKPYLEVLIEREFAQEGDLEQALELIQDSQGIQQSRELAAHHTKLAIEHLATLPPSESHQALIKIAEYAIS
RLY

Sequences:

>Translated_323_residues
MTPATSLFTPVEADLRILADNLKQLVGNRHPILFAAAEHLFGAGGKRIRPAIVLLISRATMLDQGITPRHRRLAEITEMI
HTASLVHDDVVDESEVRRGVPTVHSLFGNRIAILAGDFLFAQSSWYLANLDNLQVVKLLSEVIMDLATGEIQQGLNRFDA
SISIETYIEKSYYKTASLVANSSKAAGLLSEVSPETAEHLYAYGRHLGIAFQIVDDILDFTSTTDTLGKPVGSDLKSGNL
TAPVLFALAEKPYLEVLIEREFAQEGDLEQALELIQDSQGIQQSRELAAHHTKLAIEHLATLPPSESHQALIKIAEYAIS
RLY
>Mature_322_residues
TPATSLFTPVEADLRILADNLKQLVGNRHPILFAAAEHLFGAGGKRIRPAIVLLISRATMLDQGITPRHRRLAEITEMIH
TASLVHDDVVDESEVRRGVPTVHSLFGNRIAILAGDFLFAQSSWYLANLDNLQVVKLLSEVIMDLATGEIQQGLNRFDAS
ISIETYIEKSYYKTASLVANSSKAAGLLSEVSPETAEHLYAYGRHLGIAFQIVDDILDFTSTTDTLGKPVGSDLKSGNLT
APVLFALAEKPYLEVLIEREFAQEGDLEQALELIQDSQGIQQSRELAAHHTKLAIEHLATLPPSESHQALIKIAEYAISR
LY

Specific function: Possible role in synthesis of the nonaprenyl side chain of plastoquinone or in synthesis of other prenyl chains such as undekaprenyl pyrophosphate [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=320, Percent_Identity=39.6875, Blast_Score=231, Evalue=6e-61,
Organism=Homo sapiens, GI169808399, Length=343, Percent_Identity=30.9037900874636, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI4758430, Length=225, Percent_Identity=27.5555555555556, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI83700220, Length=225, Percent_Identity=27.5555555555556, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1789578, Length=287, Percent_Identity=36.5853658536585, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1786623, Length=226, Percent_Identity=31.858407079646, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17505681, Length=305, Percent_Identity=37.7049180327869, Blast_Score=210, Evalue=7e-55,
Organism=Saccharomyces cerevisiae, GI6319475, Length=293, Percent_Identity=40.2730375426621, Blast_Score=212, Evalue=7e-56,
Organism=Drosophila melanogaster, GI24651612, Length=319, Percent_Identity=37.3040752351097, Blast_Score=228, Evalue=3e-60,
Organism=Drosophila melanogaster, GI21356309, Length=351, Percent_Identity=28.7749287749288, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281365769, Length=223, Percent_Identity=26.9058295964126, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24660002, Length=223, Percent_Identity=26.9058295964126, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR014120
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 35488; Mature: 35357

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPATSLFTPVEADLRILADNLKQLVGNRHPILFAAAEHLFGAGGKRIRPAIVLLISRAT
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCHHHHHHHHHHHHHH
MLDQGITPRHRRLAEITEMIHTASLVHDDVVDESEVRRGVPTVHSLFGNRIAILAGDFLF
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHCCEEEEEECHHHH
AQSSWYLANLDNLQVVKLLSEVIMDLATGEIQQGLNRFDASISIETYIEKSYYKTASLVA
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NSSKAAGLLSEVSPETAEHLYAYGRHLGIAFQIVDDILDFTSTTDTLGKPVGSDLKSGNL
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCC
TAPVLFALAEKPYLEVLIEREFAQEGDLEQALELIQDSQGIQQSRELAAHHTKLAIEHLA
HHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLPPSESHQALIKIAEYAISRLY
CCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPATSLFTPVEADLRILADNLKQLVGNRHPILFAAAEHLFGAGGKRIRPAIVLLISRAT
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCHHHHHHHHHHHHHH
MLDQGITPRHRRLAEITEMIHTASLVHDDVVDESEVRRGVPTVHSLFGNRIAILAGDFLF
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHCCEEEEEECHHHH
AQSSWYLANLDNLQVVKLLSEVIMDLATGEIQQGLNRFDASISIETYIEKSYYKTASLVA
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NSSKAAGLLSEVSPETAEHLYAYGRHLGIAFQIVDDILDFTSTTDTLGKPVGSDLKSGNL
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCC
TAPVLFALAEKPYLEVLIEREFAQEGDLEQALELIQDSQGIQQSRELAAHHTKLAIEHLA
HHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLPPSESHQALIKIAEYAISRLY
CCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trans-polyisoprenyln-PP; Delta3-isopentenyl-PP [C]

Specific reaction: trans-polyisoprenyln-PP + Delta3-isopentenyl-PP = trans-polyisoprenyln-PP + pyrophosphate [C]

General reaction: Transferring alkyl or aryl groups, other than methyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]