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The map label for this gene is mtnP [H]

Identifier: 161353739

GI number: 161353739

Start: 4880647

End: 4881519

Strand: Direct

Name: mtnP [H]

Synonym: alr4054

Alternate gene names: 161353739

Gene position: 4880647-4881519 (Clockwise)

Preceding gene: 17231540

Following gene: 17231548

Centisome position: 76.1

GC content: 43.76

Gene sequence:

>873_bases
ATGGCTCACGCACAGATTGGGATTATTGGTGGTAGTGGTCTCTACAAAATGGAAGCCCTGAAAGATGTAGAAGAAGTACA
AATGGAAACGCCTTTTGGTTCGCCCTCTGATGCGTTGATTTTGGGAACATTAGATGGAACAAGAGTAGCATTTCTAGCAC
GGCATGGTCGTAATCACACGCTGTTACCTACAGAGTTACCCTTCCGTGCCAATATTTATGCTATGAAGCAATTGGGTGTG
GAGTACTTAATTTCAGCTAGCGCCGTGGGTTCGTTGAAAGAAGAAGCTAAACCACTGGATATGGTAGTCCCAGACCAGTT
TATTGACAGGACGAGAAATCGAGTTTCGACGTTTTTTGGGGAAGGTATTGTGGCTCACATTGCCTTTGGTGACCCGATTT
GCAAAAATTTAGCTGGAGTTTTAGCTGATGCGATCGCATCCTTAAATTTACCAGATGTCACACTCCACAAAGGTGGCACG
TATATTTGCATGGAAGGCCCGGCATTTTCCACCAAAGCCGAATCAAATCTATATCGTAGTTGGGGTGCAACAATCATCGG
CATGACCAATTTACCAGAAGCCAAGTTAGCTAGAGAAGCAGAAATCGCCTATGCAACTTTGGCATTAGTCACAGATTACG
ATTGTTGGCATCCAGACCACGATAGTGTCACCGTGGAAATGGTAATTGGTAATTTACTACGCAATGCAGTTAATGCTCAA
AAAGTTATTCAAGAAACCGTGCGGCGCTTGAGTGAAAATCCGCCACATAGTGAGGCTCATTCGGCTTTGAAATATGCGAT
TTTGACCAATCTAGAGAAAGCACCTGTGGCGACAAAAGAAAAGTTGGGCTTATTGTTGCAGAAGTATCTATAA

Upstream 100 bases:

>100_bases
GAATAGCAAATGCTCAATATTTATAAGCTTTATGCCTCCTCTGATACTCGCCTTTTAGGTACAATAACTGGGCAGTTCTG
CAAGCAACAGGTAAAGAATC

Downstream 100 bases:

>100_bases
TATCTTGTCTGTTTCAATACTGGTCATATTTGTAGTGATGGGTAATGGGTAATGGGTAATGGAAAACATAATTAATTACG
CACAGGGTTAAGGGTTTTAA

Product: 5'-methylthioadenosine phosphorylase

Products: NA

Alternate protein names: 5'-methylthioadenosine phosphorylase; MTA phosphorylase [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MAHAQIGIIGGSGLYKMEALKDVEEVQMETPFGSPSDALILGTLDGTRVAFLARHGRNHTLLPTELPFRANIYAMKQLGV
EYLISASAVGSLKEEAKPLDMVVPDQFIDRTRNRVSTFFGEGIVAHIAFGDPICKNLAGVLADAIASLNLPDVTLHKGGT
YICMEGPAFSTKAESNLYRSWGATIIGMTNLPEAKLAREAEIAYATLALVTDYDCWHPDHDSVTVEMVIGNLLRNAVNAQ
KVIQETVRRLSENPPHSEAHSALKYAILTNLEKAPVATKEKLGLLLQKYL

Sequences:

>Translated_290_residues
MAHAQIGIIGGSGLYKMEALKDVEEVQMETPFGSPSDALILGTLDGTRVAFLARHGRNHTLLPTELPFRANIYAMKQLGV
EYLISASAVGSLKEEAKPLDMVVPDQFIDRTRNRVSTFFGEGIVAHIAFGDPICKNLAGVLADAIASLNLPDVTLHKGGT
YICMEGPAFSTKAESNLYRSWGATIIGMTNLPEAKLAREAEIAYATLALVTDYDCWHPDHDSVTVEMVIGNLLRNAVNAQ
KVIQETVRRLSENPPHSEAHSALKYAILTNLEKAPVATKEKLGLLLQKYL
>Mature_289_residues
AHAQIGIIGGSGLYKMEALKDVEEVQMETPFGSPSDALILGTLDGTRVAFLARHGRNHTLLPTELPFRANIYAMKQLGVE
YLISASAVGSLKEEAKPLDMVVPDQFIDRTRNRVSTFFGEGIVAHIAFGDPICKNLAGVLADAIASLNLPDVTLHKGGTY
ICMEGPAFSTKAESNLYRSWGATIIGMTNLPEAKLAREAEIAYATLALVTDYDCWHPDHDSVTVEMVIGNLLRNAVNAQK
VIQETVRRLSENPPHSEAHSALKYAILTNLEKAPVATKEKLGLLLQKYL

Specific function: Catalyzes the formation of methylthio-D-ribose 1- phosphate (MTR-1-P) from methylthioadenosine (MTA) [H]

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=252, Percent_Identity=43.2539682539683, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI71980569, Length=253, Percent_Identity=41.1067193675889, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6323045, Length=302, Percent_Identity=40.0662251655629, Blast_Score=212, Evalue=7e-56,
Organism=Drosophila melanogaster, GI20130079, Length=253, Percent_Identity=39.5256916996047, Blast_Score=207, Evalue=7e-54,
Organism=Drosophila melanogaster, GI221459247, Length=252, Percent_Identity=36.1111111111111, Blast_Score=179, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010044
- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.28 [H]

Molecular weight: Translated: 31569; Mature: 31438

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS01240 PNP_MTAP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHAQIGIIGGSGLYKMEALKDVEEVQMETPFGSPSDALILGTLDGTRVAFLARHGRNHT
CCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEECCCCCCC
LLPTELPFRANIYAMKQLGVEYLISASAVGSLKEEAKPLDMVVPDQFIDRTRNRVSTFFG
CCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHC
EGIVAHIAFGDPICKNLAGVLADAIASLNLPDVTLHKGGTYICMEGPAFSTKAESNLYRS
CCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCCCHHHHHHHHH
WGATIIGMTNLPEAKLAREAEIAYATLALVTDYDCWHPDHDSVTVEMVIGNLLRNAVNAQ
HCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHH
KVIQETVRRLSENPPHSEAHSALKYAILTNLEKAPVATKEKLGLLLQKYL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AHAQIGIIGGSGLYKMEALKDVEEVQMETPFGSPSDALILGTLDGTRVAFLARHGRNHT
CCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEECCCCCCC
LLPTELPFRANIYAMKQLGVEYLISASAVGSLKEEAKPLDMVVPDQFIDRTRNRVSTFFG
CCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHC
EGIVAHIAFGDPICKNLAGVLADAIASLNLPDVTLHKGGTYICMEGPAFSTKAESNLYRS
CCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCCCHHHHHHHHH
WGATIIGMTNLPEAKLAREAEIAYATLALVTDYDCWHPDHDSVTVEMVIGNLLRNAVNAQ
HCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHH
KVIQETVRRLSENPPHSEAHSALKYAILTNLEKAPVATKEKLGLLLQKYL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA