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The map label for this gene is yflS [H]

Identifier: 39546360

GI number: 39546360

Start: 3326420

End: 3327883

Strand: Direct

Name: yflS [H]

Synonym: STM3166.S

Alternate gene names: 39546360

Gene position: 3326420-3327883 (Clockwise)

Preceding gene: 16766465

Following gene: 16766467

Centisome position: 68.48

GC content: 55.6

Gene sequence:

>1464_bases
ATGTGTGATTGTGGCGGAAAAAAATCTCAGGGCGTCAAATGGCTCCCATTCATTCTTATTCTGGTTATCGCCGCCGGACT
GTGGCAGCTAACGCCCCCTTCCGGGTTAAGCGCGCCGGCCTGGCATTCCGCGATTATTTTTGTCGCGACGATCGCCTCTA
TCGTGGCGAAAGTGCTGCCTATTGGCGCGGTCGGTATTATTGGTATCACCGTCTTTGCGCTCGCCTATGCTGCCGGCGAC
AAAACGGCCAGCGGCGCGATTACCACGGCCTTGAGCGAGCTGAACAGTTCGCTGATCTGGCTTATCGTCGTCGCCTTTAT
GATTGCCCGTGGGTTTATCAAAACCGGGCTGGGTCGGCGTATCGCCCTACAAATGATCCGTCTGTTAGGTAAACGAACGC
TGGGTCTGGCTTATGGTCTGGCGTTTGCCGATCTGATCCTCTCTCCCGCGATGCCCAGTAACACCGCGCGCTGCGGCGGC
GTGATTTACCCGATCGCCGACTCGCTGGCGCGCAGCTTTGATTCACATCCGGAAGATGAGTCTCGCAGCAAAATCGGCAC
CTTTCTGATCACCTGTATTGGCAATGTTAACGACGTCACTGCCGCACTGTTTATGACCGGTTATACGGGTAACCTGCTGG
CGGTAAAACTGGCGGCGAACGCCGGCGTTACGTTGAGCTGGGGAAGCTGGTTTATCGCCGCGCTCCTGCCTTGCCTGGTC
TCTTTTCTTATCGTCCCGCTGCTGGTCTACTGGCTGACCCGTCCGGAAATTAAACATACGCCGGATGCGCCGGATTTGGC
GCGCAAAGAGCTGGCGCAAATGGGCAGTATGACGCGCGGCGAGTGGCTCATGCTGGCGACCGTCGGCGTGTTGCTGGTGC
TATGGATTTTTGGCAGCTCGCTCGGCGTGGATGCCACGACGGCCTCTTTTGTCGGTCTCTCTATTTTATTACTGAGCGGC
GTGCTCACCTGGGAAGACGTTAAAAGCGAAAAAGGCGCCTGGGATACGTTGATTTGGTTTGCCGCGCTGCTGATGATGGC
TAACCAGTTGAAGAAACTAGGATTCACCAGCTGGTTTGGCAACCTGATTGGCGACAGCATCGGCAGCACGATGCATGGAA
CCAGTTGGATAATCATCCTGCTGCTGCTTAACGCAGCCTATTTTTATACCCACTATTTTTTTGCCAGCGGCAACGCGCAA
ATCGCCGCGCTGTATGCGGTATTTCTGGGCGTCGGTCTGCATCTGAATATACCGGCGGCGCCGATGGCGCTCATGCTGGC
GTTTACCAGCAGCCTGTACTGCTCTCTTACGCAGTATACCCACGCACGCGGCCCCATTCTTTTTGGCGCCGGCTATGTAC
CGACGGGCGTCTGGTGGCGAACGGGATTTATTATCAGTCTCTTTAATCAGGCGGTCTTTTTGACAGTCGGCCTCGCATGG
TGGAAAGTGTTAGGGTTGTATTAA

Upstream 100 bases:

>100_bases
AGTATATTTCCCCCACACACAAGCGCAGAATTATTCTGATTTTGTGAATAATTATTCATATTTATTATGAATTTACTTAA
TGCATATAAAATATTTATGG

Downstream 100 bases:

>100_bases
ACGCTTAACGCATCGATAAGCCCCTCGGTTAACGGAGAAATGGAATGACCTGCATTTTCTGTCAAATAGTTGAAGGTAAA
GCACCTTGTCATAAAGTTTG

Product: cation transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MCDCGGKKSQGVKWLPFILILVIAAGLWQLTPPSGLSAPAWHSAIIFVATIASIVAKVLPIGAVGIIGITVFALAYAAGD
KTASGAITTALSELNSSLIWLIVVAFMIARGFIKTGLGRRIALQMIRLLGKRTLGLAYGLAFADLILSPAMPSNTARCGG
VIYPIADSLARSFDSHPEDESRSKIGTFLITCIGNVNDVTAALFMTGYTGNLLAVKLAANAGVTLSWGSWFIAALLPCLV
SFLIVPLLVYWLTRPEIKHTPDAPDLARKELAQMGSMTRGEWLMLATVGVLLVLWIFGSSLGVDATTASFVGLSILLLSG
VLTWEDVKSEKGAWDTLIWFAALLMMANQLKKLGFTSWFGNLIGDSIGSTMHGTSWIIILLLLNAAYFYTHYFFASGNAQ
IAALYAVFLGVGLHLNIPAAPMALMLAFTSSLYCSLTQYTHARGPILFGAGYVPTGVWWRTGFIISLFNQAVFLTVGLAW
WKVLGLY

Sequences:

>Translated_487_residues
MCDCGGKKSQGVKWLPFILILVIAAGLWQLTPPSGLSAPAWHSAIIFVATIASIVAKVLPIGAVGIIGITVFALAYAAGD
KTASGAITTALSELNSSLIWLIVVAFMIARGFIKTGLGRRIALQMIRLLGKRTLGLAYGLAFADLILSPAMPSNTARCGG
VIYPIADSLARSFDSHPEDESRSKIGTFLITCIGNVNDVTAALFMTGYTGNLLAVKLAANAGVTLSWGSWFIAALLPCLV
SFLIVPLLVYWLTRPEIKHTPDAPDLARKELAQMGSMTRGEWLMLATVGVLLVLWIFGSSLGVDATTASFVGLSILLLSG
VLTWEDVKSEKGAWDTLIWFAALLMMANQLKKLGFTSWFGNLIGDSIGSTMHGTSWIIILLLLNAAYFYTHYFFASGNAQ
IAALYAVFLGVGLHLNIPAAPMALMLAFTSSLYCSLTQYTHARGPILFGAGYVPTGVWWRTGFIISLFNQAVFLTVGLAW
WKVLGLY
>Mature_487_residues
MCDCGGKKSQGVKWLPFILILVIAAGLWQLTPPSGLSAPAWHSAIIFVATIASIVAKVLPIGAVGIIGITVFALAYAAGD
KTASGAITTALSELNSSLIWLIVVAFMIARGFIKTGLGRRIALQMIRLLGKRTLGLAYGLAFADLILSPAMPSNTARCGG
VIYPIADSLARSFDSHPEDESRSKIGTFLITCIGNVNDVTAALFMTGYTGNLLAVKLAANAGVTLSWGSWFIAALLPCLV
SFLIVPLLVYWLTRPEIKHTPDAPDLARKELAQMGSMTRGEWLMLATVGVLLVLWIFGSSLGVDATTASFVGLSILLLSG
VLTWEDVKSEKGAWDTLIWFAALLMMANQLKKLGFTSWFGNLIGDSIGSTMHGTSWIIILLLLNAAYFYTHYFFASGNAQ
IAALYAVFLGVGLHLNIPAAPMALMLAFTSSLYCSLTQYTHARGPILFGAGYVPTGVWWRTGFIISLFNQAVFLTVGLAW
WKVLGLY

Specific function: Might be a malate transporter [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family [H]

Homologues:

Organism=Escherichia coli, GI1786986, Length=472, Percent_Identity=36.864406779661, Blast_Score=281, Evalue=8e-77,
Organism=Escherichia coli, GI1786829, Length=482, Percent_Identity=32.5726141078838, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI1789444, Length=486, Percent_Identity=35.1851851851852, Blast_Score=256, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 52214; Mature: 52214

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCDCGGKKSQGVKWLPFILILVIAAGLWQLTPPSGLSAPAWHSAIIFVATIASIVAKVLP
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
IGAVGIIGITVFALAYAAGDKTASGAITTALSELNSSLIWLIVVAFMIARGFIKTGLGRR
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHH
IALQMIRLLGKRTLGLAYGLAFADLILSPAMPSNTARCGGVIYPIADSLARSFDSHPEDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCHH
SRSKIGTFLITCIGNVNDVTAALFMTGYTGNLLAVKLAANAGVTLSWGSWFIAALLPCLV
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHHH
SFLIVPLLVYWLTRPEIKHTPDAPDLARKELAQMGSMTRGEWLMLATVGVLLVLWIFGSS
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
LGVDATTASFVGLSILLLSGVLTWEDVKSEKGAWDTLIWFAALLMMANQLKKLGFTSWFG
CCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
NLIGDSIGSTMHGTSWIIILLLLNAAYFYTHYFFASGNAQIAALYAVFLGVGLHLNIPAA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCEECCCHH
PMALMLAFTSSLYCSLTQYTHARGPILFGAGYVPTGVWWRTGFIISLFNQAVFLTVGLAW
HHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WKVLGLY
HHHHCCC
>Mature Secondary Structure
MCDCGGKKSQGVKWLPFILILVIAAGLWQLTPPSGLSAPAWHSAIIFVATIASIVAKVLP
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
IGAVGIIGITVFALAYAAGDKTASGAITTALSELNSSLIWLIVVAFMIARGFIKTGLGRR
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHH
IALQMIRLLGKRTLGLAYGLAFADLILSPAMPSNTARCGGVIYPIADSLARSFDSHPEDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCHH
SRSKIGTFLITCIGNVNDVTAALFMTGYTGNLLAVKLAANAGVTLSWGSWFIAALLPCLV
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHHH
SFLIVPLLVYWLTRPEIKHTPDAPDLARKELAQMGSMTRGEWLMLATVGVLLVLWIFGSS
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
LGVDATTASFVGLSILLLSGVLTWEDVKSEKGAWDTLIWFAALLMMANQLKKLGFTSWFG
CCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
NLIGDSIGSTMHGTSWIIILLLLNAAYFYTHYFFASGNAQIAALYAVFLGVGLHLNIPAA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCEECCCHH
PMALMLAFTSSLYCSLTQYTHARGPILFGAGYVPTGVWWRTGFIISLFNQAVFLTVGLAW
HHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WKVLGLY
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 12949159 [H]