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The map label for this gene is ywbI [H]

Identifier: 39546302

GI number: 39546302

Start: 826453

End: 827343

Strand: Direct

Name: ywbI [H]

Synonym: STM0763.s

Alternate gene names: 39546302

Gene position: 826453-827343 (Clockwise)

Preceding gene: 16764125

Following gene: 16764130

Centisome position: 17.01

GC content: 34.9

Gene sequence:

>891_bases
ATGGAAATTAGACAATTAGAATATTTTGTAAGCGCTTCTTTGTTAGGTAACTTAACCAGAGTTGCTGAGCGGCATTTTGT
TTCTCAACCTAATATCACCATTGCTATTAAGAAGTTAGAGACTGAATTAGGGGTGACATTATTTGATAGAAAGAAAAATA
AACTTGTCCTTACTGAGGAGGGCATGTTTTTCTTACAAAAAATTGAACCTATCCTTATTGCGTTAAAAAATAGCGTAGCG
GAAATGAAAGATTATCGTAATGAAAATGGTGGCATAGTAACTTTGGGGATCCCACCGATGATAAGTTTGTTTCTTTTTTC
ACCGCTCTTCAAGCATTTCCGAGAGATTTATCCAGAGATGGAACTCTCTCTTGTTGAAGAGGGGACTTTTGGTTTACATG
ATAAACTTTCTGCTGGAGAGCTGGATCTTGCTATTGTTATTATTAATGACTGTCCAAAAGAATTAGTTACGGTACCATTA
ATGACTCAGCAGCACGTGGTATGTATGTCAGATAAACATCCTCTGGCAAAAAAGGATAGTATCGATTGGGAAGATCTACA
ATATGAGCCATTGATACTAATGAAAAAAGATTCCTGGCATAGAAAAACGATTATTGAAGAATGTACAAAGCGAGGAATTC
ATACACATATTTTTCTATCATCAAACAGGGTTCAAACCAACATAGATCTGGTTGCTAAAAATGAAGGAATTTCTTTCATT
TTGGACGCTGTCGATCTTAAAGCCGAAAAAGTAATAACCAAGGCCATGACTGAGCCGACTTATGTTACGATTGGTTTGGC
CTGGAAGAAAGATAAATATTTATCATATGCAACCAGAGCGTTAATTAAATTCATTGAGGATTATATTAAAGAACATTTTA
CAATTAAATAA

Upstream 100 bases:

>100_bases
TATCCATTGATCACATTTTCATGATATTCGTATTCATTGTAGGAAGGAAATATGTTATTTTTATTAAATGATAAATTTTA
TTTATAGTAGTGGAAAATAG

Downstream 100 bases:

>100_bases
TTATATTTGTTCTTCAACAAAAATTTCCCATAGCTCTTCGGCATCTGGAGGCATTCTCTTGGCTGGTCTATAAAGTCTTA
TTTCTATGGGTACCCATAAA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MEIRQLEYFVSASLLGNLTRVAERHFVSQPNITIAIKKLETELGVTLFDRKKNKLVLTEEGMFFLQKIEPILIALKNSVA
EMKDYRNENGGIVTLGIPPMISLFLFSPLFKHFREIYPEMELSLVEEGTFGLHDKLSAGELDLAIVIINDCPKELVTVPL
MTQQHVVCMSDKHPLAKKDSIDWEDLQYEPLILMKKDSWHRKTIIEECTKRGIHTHIFLSSNRVQTNIDLVAKNEGISFI
LDAVDLKAEKVITKAMTEPTYVTIGLAWKKDKYLSYATRALIKFIEDYIKEHFTIK

Sequences:

>Translated_296_residues
MEIRQLEYFVSASLLGNLTRVAERHFVSQPNITIAIKKLETELGVTLFDRKKNKLVLTEEGMFFLQKIEPILIALKNSVA
EMKDYRNENGGIVTLGIPPMISLFLFSPLFKHFREIYPEMELSLVEEGTFGLHDKLSAGELDLAIVIINDCPKELVTVPL
MTQQHVVCMSDKHPLAKKDSIDWEDLQYEPLILMKKDSWHRKTIIEECTKRGIHTHIFLSSNRVQTNIDLVAKNEGISFI
LDAVDLKAEKVITKAMTEPTYVTIGLAWKKDKYLSYATRALIKFIEDYIKEHFTIK
>Mature_296_residues
MEIRQLEYFVSASLLGNLTRVAERHFVSQPNITIAIKKLETELGVTLFDRKKNKLVLTEEGMFFLQKIEPILIALKNSVA
EMKDYRNENGGIVTLGIPPMISLFLFSPLFKHFREIYPEMELSLVEEGTFGLHDKLSAGELDLAIVIINDCPKELVTVPL
MTQQHVVCMSDKHPLAKKDSIDWEDLQYEPLILMKKDSWHRKTIIEECTKRGIHTHIFLSSNRVQTNIDLVAKNEGISFI
LDAVDLKAEKVITKAMTEPTYVTIGLAWKKDKYLSYATRALIKFIEDYIKEHFTIK

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=285, Percent_Identity=25.6140350877193, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1790399, Length=299, Percent_Identity=26.0869565217391, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI145693105, Length=281, Percent_Identity=26.6903914590747, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786401, Length=306, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788296, Length=229, Percent_Identity=28.82096069869, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789204, Length=292, Percent_Identity=21.5753424657534, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788748, Length=288, Percent_Identity=25, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788887, Length=186, Percent_Identity=31.7204301075269, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI2367136, Length=253, Percent_Identity=24.1106719367589, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789506, Length=280, Percent_Identity=22.8571428571429, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787879, Length=196, Percent_Identity=26.0204081632653, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787601, Length=183, Percent_Identity=24.5901639344262, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788481, Length=206, Percent_Identity=25.7281553398058, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787530, Length=195, Percent_Identity=25.1282051282051, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34012; Mature: 34012

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRQLEYFVSASLLGNLTRVAERHFVSQPNITIAIKKLETELGVTLFDRKKNKLVLTEE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHCEEEEECCCCEEEEEEC
GMFFLQKIEPILIALKNSVAEMKDYRNENGGIVTLGIPPMISLFLFSPLFKHFREIYPEM
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCC
ELSLVEEGTFGLHDKLSAGELDLAIVIINDCPKELVTVPLMTQQHVVCMSDKHPLAKKDS
EEEEECCCCCCCCCCCCCCCEEEEEEEECCCCHHHEEECCCCCCEEEEECCCCCCCCCCC
IDWEDLQYEPLILMKKDSWHRKTIIEECTKRGIHTHIFLSSNRVQTNIDLVAKNEGISFI
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCEEEEEEEEEEECCCCEEE
LDAVDLKAEKVITKAMTEPTYVTIGLAWKKDKYLSYATRALIKFIEDYIKEHFTIK
EEHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEIRQLEYFVSASLLGNLTRVAERHFVSQPNITIAIKKLETELGVTLFDRKKNKLVLTEE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHCEEEEECCCCEEEEEEC
GMFFLQKIEPILIALKNSVAEMKDYRNENGGIVTLGIPPMISLFLFSPLFKHFREIYPEM
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCC
ELSLVEEGTFGLHDKLSAGELDLAIVIINDCPKELVTVPLMTQQHVVCMSDKHPLAKKDS
EEEEECCCCCCCCCCCCCCCEEEEEEEECCCCHHHEEECCCCCCEEEEECCCCCCCCCCC
IDWEDLQYEPLILMKKDSWHRKTIIEECTKRGIHTHIFLSSNRVQTNIDLVAKNEGISFI
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCEEEEEEEEEEECCCCEEE
LDAVDLKAEKVITKAMTEPTYVTIGLAWKKDKYLSYATRALIKFIEDYIKEHFTIK
EEHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]