Click here to switch to the map view.

The map label for this gene is hfq [H]

Identifier: 16767607

GI number: 16767607

Start: 4604575

End: 4604883

Strand: Direct

Name: hfq [H]

Synonym: STM4361

Alternate gene names: 16767607

Gene position: 4604575-4604883 (Clockwise)

Preceding gene: 16767606

Following gene: 16767608

Centisome position: 94.79

GC content: 49.84

Gene sequence:

>309_bases
ATGGCTAAGGGGCAATCTTTACAAGATCCGTTCCTGAACGCATTGCGTCGGGAACGTGTTCCAGTTTCTATTTATTTGGT
GAATGGTATTAAGCTGCAAGGTCAAATCGAGTCCTTTGATCAGTTCGTGATCCTGTTGAAGAACACGGTCAGCCAGATGG
TTTATAAGCACGCGATTTCTACTGTTGTCCCGTCTCGCCCGGTTTCCCATCACAGCAACAATGCCGGTGGCGGCGCCAGC
AATAACTACCATCACGGTAGCAACGCGCAGGGGTCTACTGCGCAACAGGACAGCGAAGAGACTGAATAA

Upstream 100 bases:

>100_bases
GGTGCTATCGCAGACTGAATGTGTACAATTGAGACGTATCGTGCGCAATTTTTCAGAATCGAAAGGTTCAAAGTACAAAT
AAGCATATAAGGAAAAGAGA

Downstream 100 bases:

>100_bases
GTTCACGCGCTGTTTATCCATGTCGGGGGCGTCGGATAATCGCCCCCGCTGGTTATTAAGAGGGTTTACGCTTGTTTGAC
CGTTATGATGCCGGTGAGCA

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: HF-1; Host factor-I protein; HF-I [H]

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGAS
NNYHHGSNAQGSTAQQDSEETE

Sequences:

>Translated_102_residues
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGAS
NNYHHGSNAQGSTAQQDSEETE
>Mature_101_residues
AKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGASN
NYHHGSNAQGSTAQQDSEETE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=102, Percent_Identity=94.1176470588235, Blast_Score=201, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 11134; Mature: 11002

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAIS
CCCCCCCCCHHHHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVVPSRPVSHHSNNAGGGASNNYHHGSNAQGSTAQQDSEETE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAIS
CCCCCCCCHHHHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVVPSRPVSHHSNNAGGGASNNYHHGSNAQGSTAQQDSEETE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA