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The map label for this gene is yjdB

Identifier: 16767543

GI number: 16767543

Start: 4534384

End: 4536027

Strand: Reverse

Name: yjdB

Synonym: STM4293

Alternate gene names: 16767543

Gene position: 4536027-4534384 (Counterclockwise)

Preceding gene: 16767544

Following gene: 16767542

Centisome position: 93.38

GC content: 49.39

Gene sequence:

>1644_bases
ATGTTAAAGCGCTTTCTTAAAAGACCTGTTCTTGGGCAAATCGCCTGGCTTCTGCTTTTTTCCTTTTATATTGCCGTCTG
CCTGAACATTGCGTTCTACAAGCAGGTACTACAAGACCTACCGTTAAACTCGCTGCGCAATGTGCTGGTGTTTATTTCCA
TGCCGGTCGTCGCGTTTAGCGTGGTCAATAGTGTGCTGACGCTGGCCTCATTTATTTGGCTAAACCGACTGCTGGCCTGC
GTTTTTATTCTGGTCGGCGCTGCCGCGCAGTATTTTATTTTGACTTACGGCATCATCATCGATCGCTCCATGATCGCCAA
TATGATGGATACCACGCCCGCGGAAACCTTTGCGCTGATGACGCCGCAAATGGTGCTGACGCTGGGATTAAGCGGCGTTC
TGGCAGCCGTGATTGCCTTCTGGGTCAAAATCCGTCCGGCGACGCCGCGCTTACGTAGCGGGCTTTACCGCCTGGCCAGC
GTCCTGATCTCTATTTTATTAGTTATTCTGGTCGCCGCCTTTTTCTATAAAGATTACGCCTCGTTATTTCGAAATAATAA
ACAGTTGATCAAAGCATTAAGCCCATCGAACAGTATTGTCGCCAGTTGGTCATGGTATTCACATCAACGGCTGGCGAATT
TGCCGCTGGTACGCATTGGCGAGGATGCCCATCGCAATCCATTAATGCTGAAAGGCGATCGCAAAAACCTGACGATTCTC
ATCGTTGGCGAAACCTCGCGCGGCGATGATTTCTCTCTTGGCGGCTATCCGCGCGACACCAATCCGCGGCTGGCGAAAGA
CGATGTGATCTACTTCCCGCATACCACCTCTTGCGGTACGGCGACCGCGATCTCCGTTCCCTGCATGTTTTCTGATATGC
CGCGCAAACATTATGACGAAGAGCTGGCGCATCACCAGGAAGGGCTGCTGGATATTATCCAGCGCGCGGGGATTAACGTA
CTGTGGAATGATAATGACGGCGGCTGTAAAGGCGCATGCGATCGCGTTCCGCATCAAAATGTCACCGAGCTAAACCTGCC
CGGACAATGTATCGACGGCGAGTGCTACGATGAAGTGTTATTTCACGGTCTGGAAGACTATATCGACCATTTGAAAGGCG
ATGGCGTTATTGTATTACATACCATCGGCAGCCACGGCCCAACCTATTACAACCGTTATCCACCGCAGTTTAAAAAATTT
ACCCCAACCTGTGACACTAACGAAATTCAGAACTGTTCCCAAGAGCAGTTGATCAACACCTATGATAATACCGTGCTGTA
CGTGGACTATATTGTAGATAAAGCCATTAACCTGCTGAAATCTCATCAGGATAAATTCACCACCAGCCTGGTCTATCTTT
CCGATCACGGCGAATCATTGGGTGAAAATGGCGTTTATTTACACGGTTTGCCGTATTCCATTGCGCCGGATACGCAAAAA
CATGTCCCGATGCTCATTTGGCTTTCTAAAGATTATCAACAGCGTTATCAGGTGGATCAGGCCTGCCTGCAAAAACGGGC
GAGCACGCTGGATTATTCACAGGACAATCTTTTCTCAACCATGCTGGGATTAACCGGCGTACAAACGACGTATTACCAGG
CCGCAGATGATATTCTGCAACCGTGCAGGAGACTAAGCGAATGA

Upstream 100 bases:

>100_bases
ATAGCGCAGGTTATCCGGCCGCCACCAACATTAAGTTCTTAAGGTTCACTTAATTTTACTTTGTCACGATTAGCGTCACC
GAATCGATGGACGCATCAAC

Downstream 100 bases:

>100_bases
AGATACTGATTGTTGAAGACGACACGCTATTATTACAGGGGTTAATACTCGCCGCGCAAACCGAAGGCTATGCGTGTGAT
GGCGTTTCGACAGCGCGTGC

Product: cell division protein

Products: NA

Alternate protein names: Polymyxin resistance protein pmrC

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MLKRFLKRPVLGQIAWLLLFSFYIAVCLNIAFYKQVLQDLPLNSLRNVLVFISMPVVAFSVVNSVLTLASFIWLNRLLAC
VFILVGAAAQYFILTYGIIIDRSMIANMMDTTPAETFALMTPQMVLTLGLSGVLAAVIAFWVKIRPATPRLRSGLYRLAS
VLISILLVILVAAFFYKDYASLFRNNKQLIKALSPSNSIVASWSWYSHQRLANLPLVRIGEDAHRNPLMLKGDRKNLTIL
IVGETSRGDDFSLGGYPRDTNPRLAKDDVIYFPHTTSCGTATAISVPCMFSDMPRKHYDEELAHHQEGLLDIIQRAGINV
LWNDNDGGCKGACDRVPHQNVTELNLPGQCIDGECYDEVLFHGLEDYIDHLKGDGVIVLHTIGSHGPTYYNRYPPQFKKF
TPTCDTNEIQNCSQEQLINTYDNTVLYVDYIVDKAINLLKSHQDKFTTSLVYLSDHGESLGENGVYLHGLPYSIAPDTQK
HVPMLIWLSKDYQQRYQVDQACLQKRASTLDYSQDNLFSTMLGLTGVQTTYYQAADDILQPCRRLSE

Sequences:

>Translated_547_residues
MLKRFLKRPVLGQIAWLLLFSFYIAVCLNIAFYKQVLQDLPLNSLRNVLVFISMPVVAFSVVNSVLTLASFIWLNRLLAC
VFILVGAAAQYFILTYGIIIDRSMIANMMDTTPAETFALMTPQMVLTLGLSGVLAAVIAFWVKIRPATPRLRSGLYRLAS
VLISILLVILVAAFFYKDYASLFRNNKQLIKALSPSNSIVASWSWYSHQRLANLPLVRIGEDAHRNPLMLKGDRKNLTIL
IVGETSRGDDFSLGGYPRDTNPRLAKDDVIYFPHTTSCGTATAISVPCMFSDMPRKHYDEELAHHQEGLLDIIQRAGINV
LWNDNDGGCKGACDRVPHQNVTELNLPGQCIDGECYDEVLFHGLEDYIDHLKGDGVIVLHTIGSHGPTYYNRYPPQFKKF
TPTCDTNEIQNCSQEQLINTYDNTVLYVDYIVDKAINLLKSHQDKFTTSLVYLSDHGESLGENGVYLHGLPYSIAPDTQK
HVPMLIWLSKDYQQRYQVDQACLQKRASTLDYSQDNLFSTMLGLTGVQTTYYQAADDILQPCRRLSE
>Mature_547_residues
MLKRFLKRPVLGQIAWLLLFSFYIAVCLNIAFYKQVLQDLPLNSLRNVLVFISMPVVAFSVVNSVLTLASFIWLNRLLAC
VFILVGAAAQYFILTYGIIIDRSMIANMMDTTPAETFALMTPQMVLTLGLSGVLAAVIAFWVKIRPATPRLRSGLYRLAS
VLISILLVILVAAFFYKDYASLFRNNKQLIKALSPSNSIVASWSWYSHQRLANLPLVRIGEDAHRNPLMLKGDRKNLTIL
IVGETSRGDDFSLGGYPRDTNPRLAKDDVIYFPHTTSCGTATAISVPCMFSDMPRKHYDEELAHHQEGLLDIIQRAGINV
LWNDNDGGCKGACDRVPHQNVTELNLPGQCIDGECYDEVLFHGLEDYIDHLKGDGVIVLHTIGSHGPTYYNRYPPQFKKF
TPTCDTNEIQNCSQEQLINTYDNTVLYVDYIVDKAINLLKSHQDKFTTSLVYLSDHGESLGENGVYLHGLPYSIAPDTQK
HVPMLIWLSKDYQQRYQVDQACLQKRASTLDYSQDNLFSTMLGLTGVQTTYYQAADDILQPCRRLSE

Specific function: Catalyzes the addition of a phosphoethanolamine moiety to the lipid A. The phosphoethanolamine modification is required for resistance to polymyxin

COG id: COG2194

COG function: function code R; Predicted membrane-associated, metal-dependent hydrolase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoethanolamine transferase family. EptA subfamily

Homologues:

Organism=Escherichia coli, GI87082372, Length=547, Percent_Identity=82.4497257769653, Blast_Score=939, Evalue=0.0,
Organism=Escherichia coli, GI87082286, Length=480, Percent_Identity=25.8333333333333, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI87082223, Length=440, Percent_Identity=24.0909090909091, Blast_Score=86, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EPTA_SALTY (P36555)

Other databases:

- EMBL:   L13395
- EMBL:   AE006468
- PIR:   A40656
- RefSeq:   NP_463158.1
- ProteinModelPortal:   P36555
- PRIDE:   P36555
- GeneID:   1255819
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM4293
- NMPDR:   fig|99287.1.peg.4131
- HOGENOM:   HBG478687
- OMA:   IDRSMIT
- ProtClustDB:   PRK11598
- BioCyc:   STYP99287:STM4293-MONOMER
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR012549
- InterPro:   IPR000917
- Gene3D:   G3DSA:3.40.720.10

Pfam domain/function: PF08019 DUF1705; PF00884 Sulfatase; SSF53649 Alkaline_phosphatase_core

EC number: NA

Molecular weight: Translated: 61620; Mature: 61620

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x144ad528)-; HASH(0x12ccd184)-; HASH(0x421b044c)-; HASH(0x145f59dc)-; HASH(0x421aff84)-;

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRFLKRPVLGQIAWLLLFSFYIAVCLNIAFYKQVLQDLPLNSLRNVLVFISMPVVAFS
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VVNSVLTLASFIWLNRLLACVFILVGAAAQYFILTYGIIIDRSMIANMMDTTPAETFALM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TPQMVLTLGLSGVLAAVIAFWVKIRPATPRLRSGLYRLASVLISILLVILVAAFFYKDYA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLFRNNKQLIKALSPSNSIVASWSWYSHQRLANLPLVRIGEDAHRNPLMLKGDRKNLTIL
HHHHCCHHHHHHHCCCCCEEEEECHHHHHHHHCCCEEEECCCCCCCCEEEECCCCCEEEE
IVGETSRGDDFSLGGYPRDTNPRLAKDDVIYFPHTTSCGTATAISVPCMFSDMPRKHYDE
EEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEECCHHHCCCCHHHHHH
ELAHHQEGLLDIIQRAGINVLWNDNDGGCKGACDRVPHQNVTELNLPGQCIDGECYDEVL
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
FHGLEDYIDHLKGDGVIVLHTIGSHGPTYYNRYPPQFKKFTPTCDTNEIQNCSQEQLINT
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHCCCCCCCCHHHHCCCHHHHHHH
YDNTVLYVDYIVDKAINLLKSHQDKFTTSLVYLSDHGESLGENGVYLHGLPYSIAPDTQK
HCCCEEEHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCC
HVPMLIWLSKDYQQRYQVDQACLQKRASTLDYSQDNLFSTMLGLTGVQTTYYQAADDILQ
CCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
PCRRLSE
HHHHHCH
>Mature Secondary Structure
MLKRFLKRPVLGQIAWLLLFSFYIAVCLNIAFYKQVLQDLPLNSLRNVLVFISMPVVAFS
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VVNSVLTLASFIWLNRLLACVFILVGAAAQYFILTYGIIIDRSMIANMMDTTPAETFALM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TPQMVLTLGLSGVLAAVIAFWVKIRPATPRLRSGLYRLASVLISILLVILVAAFFYKDYA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLFRNNKQLIKALSPSNSIVASWSWYSHQRLANLPLVRIGEDAHRNPLMLKGDRKNLTIL
HHHHCCHHHHHHHCCCCCEEEEECHHHHHHHHCCCEEEECCCCCCCCEEEECCCCCEEEE
IVGETSRGDDFSLGGYPRDTNPRLAKDDVIYFPHTTSCGTATAISVPCMFSDMPRKHYDE
EEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEECCHHHCCCCHHHHHH
ELAHHQEGLLDIIQRAGINVLWNDNDGGCKGACDRVPHQNVTELNLPGQCIDGECYDEVL
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
FHGLEDYIDHLKGDGVIVLHTIGSHGPTYYNRYPPQFKKFTPTCDTNEIQNCSQEQLINT
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHCCCCCCCCHHHHCCCHHHHHHH
YDNTVLYVDYIVDKAINLLKSHQDKFTTSLVYLSDHGESLGENGVYLHGLPYSIAPDTQK
HCCCEEEHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCC
HVPMLIWLSKDYQQRYQVDQACLQKRASTLDYSQDNLFSTMLGLTGVQTTYYQAADDILQ
CCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
PCRRLSE
HHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8391535; 11677609