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The map label for this gene is nrfC [H]

Identifier: 16767529

GI number: 16767529

Start: 4518215

End: 4518886

Strand: Direct

Name: nrfC [H]

Synonym: STM4279

Alternate gene names: 16767529

Gene position: 4518215-4518886 (Clockwise)

Preceding gene: 39546394

Following gene: 16767530

Centisome position: 93.02

GC content: 57.59

Gene sequence:

>672_bases
ATGAGTTGCACCCGACGTCAATTTATTACCCGCGTCGGCGCGCTGGCGGCGGTCAGTGGGATGGCAGGACGCGTTGTAGC
GAACACGTTGAATATTAATGGCGTGCGTTATGGCATGGTACACGATGAGTCATTATGCATCGGCTGCACGGCCTGCATGG
ATGCCTGTCGGGAAGTCAACACCGTGCCGGAAGGCGTATCGCGCCTGACGATTATTCGCAGCGAGCCGCAGGGGACGTTT
CCTGATGTGAAGTATCGCTTCTTCCGCCACTCGTGCCAGCATTGCGACCATGCCCCCTGCGTTGACGTCTGCCCGACGGG
GGCATCATTCCGCGATGCCGCCAGCGGTATTGTCGACGTGAATCCGGACCTTTGCGTCGGCTGCCAGTACTGCATTGCCG
CGTGTCCCTACCGCGTGCGCTTTATCCATCCGGTCAGTAAGACGGCGGATAAATGCGATTTCTGCCGGAAAACCAACCTG
AAAGCGGGCAAACAGCCCGCCTGCGTTGAGTCATGCCCGACGAAGGCGCTGACGTTTGGTAATCTGGACGATCCCAACAG
CGATATTTCCCGTTTGTTGCGGCAGAAAACCACCTATCGTTACAAGCTGGCGCTGGGCACAAAACCGAAGGTCTACCGCG
TTCCCTTTAACTATGGGGAGGTGAGCCAATGA

Upstream 100 bases:

>100_bases
GCGAGAAAGGGCGGATCAAAATATGCGTGGATTGCCACAGCGATCAGCGTACTAACCCGCACTTTAATCCGGCGTCCGTT
CCGTTGCTTAAGGAGCAGCC

Downstream 100 bases:

>100_bases
CATCCGCTTCTGCATTTCATTTTGCATCACTGGTGTGGGACTGGCCCATCGCCATCTATCTGTTTCTGATTGGCATCTCC
GCCGGACTGGTTACGTTGGC

Product: formate-dependent nitrite reductase

Products: oxidized cytochrome C552; NH3 [C]

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MSCTRRQFITRVGALAAVSGMAGRVVANTLNINGVRYGMVHDESLCIGCTACMDACREVNTVPEGVSRLTIIRSEPQGTF
PDVKYRFFRHSCQHCDHAPCVDVCPTGASFRDAASGIVDVNPDLCVGCQYCIAACPYRVRFIHPVSKTADKCDFCRKTNL
KAGKQPACVESCPTKALTFGNLDDPNSDISRLLRQKTTYRYKLALGTKPKVYRVPFNYGEVSQ

Sequences:

>Translated_223_residues
MSCTRRQFITRVGALAAVSGMAGRVVANTLNINGVRYGMVHDESLCIGCTACMDACREVNTVPEGVSRLTIIRSEPQGTF
PDVKYRFFRHSCQHCDHAPCVDVCPTGASFRDAASGIVDVNPDLCVGCQYCIAACPYRVRFIHPVSKTADKCDFCRKTNL
KAGKQPACVESCPTKALTFGNLDDPNSDISRLLRQKTTYRYKLALGTKPKVYRVPFNYGEVSQ
>Mature_222_residues
SCTRRQFITRVGALAAVSGMAGRVVANTLNINGVRYGMVHDESLCIGCTACMDACREVNTVPEGVSRLTIIRSEPQGTFP
DVKYRFFRHSCQHCDHAPCVDVCPTGASFRDAASGIVDVNPDLCVGCQYCIAACPYRVRFIHPVSKTADKCDFCRKTNLK
AGKQPACVESCPTKALTFGNLDDPNSDISRLLRQKTTYRYKLALGTKPKVYRVPFNYGEVSQ

Specific function: Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI2367345, Length=223, Percent_Identity=91.0313901345291, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI226510944, Length=213, Percent_Identity=49.2957746478873, Blast_Score=213, Evalue=7e-57,
Organism=Escherichia coli, GI1789370, Length=259, Percent_Identity=31.6602316602317, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787872, Length=169, Percent_Identity=36.094674556213, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787122, Length=157, Percent_Identity=35.6687898089172, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787749, Length=154, Percent_Identity=31.8181818181818, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1790326, Length=178, Percent_Identity=29.7752808988764, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788811, Length=161, Percent_Identity=33.5403726708075, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082180, Length=176, Percent_Identity=30.1136363636364, Blast_Score=71, Evalue=4e-14,
Organism=Escherichia coli, GI1789079, Length=204, Percent_Identity=27.9411764705882, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1787740, Length=111, Percent_Identity=30.6306306306306, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789067, Length=159, Percent_Identity=32.7044025157233, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI87082179, Length=92, Percent_Identity=39.1304347826087, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787478, Length=103, Percent_Identity=32.0388349514563, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI2367245, Length=158, Percent_Identity=32.2784810126582, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787963, Length=162, Percent_Identity=27.1604938271605, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR017567
- InterPro:   IPR006311 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24532; Mature: 24401

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
9.4 %Cys+Met (Translated Protein)
7.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
9.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCTRRQFITRVGALAAVSGMAGRVVANTLNINGVRYGMVHDESLCIGCTACMDACREVN
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEECCCCEEHHHHHHHHHHHHC
TVPEGVSRLTIIRSEPQGTFPDVKYRFFRHSCQHCDHAPCVDVCPTGASFRDAASGIVDV
CCHHCHHEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCEEEC
NPDLCVGCQYCIAACPYRVRFIHPVSKTADKCDFCRKTNLKAGKQPACVESCPTKALTFG
CCCHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEEC
NLDDPNSDISRLLRQKTTYRYKLALGTKPKVYRVPFNYGEVSQ
CCCCCCHHHHHHHHHHCCEEEEEEECCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
SCTRRQFITRVGALAAVSGMAGRVVANTLNINGVRYGMVHDESLCIGCTACMDACREVN
CCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEECCCCEEHHHHHHHHHHHHC
TVPEGVSRLTIIRSEPQGTFPDVKYRFFRHSCQHCDHAPCVDVCPTGASFRDAASGIVDV
CCHHCHHEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCEEEC
NPDLCVGCQYCIAACPYRVRFIHPVSKTADKCDFCRKTNLKAGKQPACVESCPTKALTFG
CCCHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEEC
NLDDPNSDISRLLRQKTTYRYKLALGTKPKVYRVPFNYGEVSQ
CCCCCCHHHHHHHHHHCCEEEEEEECCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced cytochrome C552; nitrite [C]

Specific reaction: reduced cytochrome C552 + nitrite = oxidized cytochrome C552 + NH3 [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]