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The map label for this gene is cidA [H]

Identifier: 16767521

GI number: 16767521

Start: 4510377

End: 4510787

Strand: Direct

Name: cidA [H]

Synonym: STM4271

Alternate gene names: 16767521

Gene position: 4510377-4510787 (Clockwise)

Preceding gene: 16767519

Following gene: 16767522

Centisome position: 92.86

GC content: 54.74

Gene sequence:

>411_bases
ATGGCTGTGGCGATAAGCCGCGTTACGCCTGCCGTTGTGCAACGACTCCAGGTACCGGTTCAGGTACTGCTCTATGCAGG
TTTATTCATTTTTTCCCAATATCTTGTCTCCTGGCTGCACCTGCCGTTGCCCGCGAATCTGGTCGGCATGGTGCTTATGT
TGGCGCTGATCGTTTGCCGGATTATTCCGCTTAGCTGGGTACGCGCAGGCGCACGCTGGCTGCTGGCGGAGATGCTGTTA
TTCTTTGTTCCCGCCGTCGTGGCGGTAGTGAACTATGCCCATCTGTTACTGGTGGACGGCTGGCGCATTTTCTCGGTGAT
AGCGATCAGTACCTTAATGGTACTCGGCGCGACGGCGTGGGTGGTGGATAAAGTGTATCGCTATGAGATGAGCAGGCTAA
ACCGTGAATAA

Upstream 100 bases:

>100_bases
TATTCCTTCCGACTATGCCTGCAATGATTTTAATTCATTTCTGCCCGTGACGGAGGTTCTCTATACTGGCGCTCCGTATT
ATTTTTCAGGACATTCCCTC

Downstream 100 bases:

>100_bases
CGTTCAGTTAAGCGTACTGTGCCTGGTGATTACGCTGGGAATTTATTTCGCCAATAAGCGCCTGTATCGCCGTTTTCGCA
AATTGCCGTTGATGCCATTA

Product: inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MAVAISRVTPAVVQRLQVPVQVLLYAGLFIFSQYLVSWLHLPLPANLVGMVLMLALIVCRIIPLSWVRAGARWLLAEMLL
FFVPAVVAVVNYAHLLLVDGWRIFSVIAISTLMVLGATAWVVDKVYRYEMSRLNRE

Sequences:

>Translated_136_residues
MAVAISRVTPAVVQRLQVPVQVLLYAGLFIFSQYLVSWLHLPLPANLVGMVLMLALIVCRIIPLSWVRAGARWLLAEMLL
FFVPAVVAVVNYAHLLLVDGWRIFSVIAISTLMVLGATAWVVDKVYRYEMSRLNRE
>Mature_135_residues
AVAISRVTPAVVQRLQVPVQVLLYAGLFIFSQYLVSWLHLPLPANLVGMVLMLALIVCRIIPLSWVRAGARWLLAEMLLF
FVPAVVAVVNYAHLLLVDGWRIFSVIAISTLMVLGATAWVVDKVYRYEMSRLNRE

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 15307; Mature: 15176

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAISRVTPAVVQRLQVPVQVLLYAGLFIFSQYLVSWLHLPLPANLVGMVLMLALIVCR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IIPLSWVRAGARWLLAEMLLFFVPAVVAVVNYAHLLLVDGWRIFSVIAISTLMVLGATAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVDKVYRYEMSRLNRE
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVAISRVTPAVVQRLQVPVQVLLYAGLFIFSQYLVSWLHLPLPANLVGMVLMLALIVCR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IIPLSWVRAGARWLLAEMLLFFVPAVVAVVNYAHLLLVDGWRIFSVIAISTLMVLGATAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVDKVYRYEMSRLNRE
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA