Click here to switch to the map view.

The map label for this gene is prtE [H]

Identifier: 16767510

GI number: 16767510

Start: 4481180

End: 4482457

Strand: Direct

Name: prtE [H]

Synonym: STM4260

Alternate gene names: 16767510

Gene position: 4481180-4482457 (Clockwise)

Preceding gene: 16767509

Following gene: 16767511

Centisome position: 92.25

GC content: 34.51

Gene sequence:

>1278_bases
ATGAATAGAAGACAAAGCGATCATCTCATGATGATAATTATTTCTTTGACGATCTTAATTATTATCCTTACCTACTTTAT
AGAAATTAATTCAGTGGTTCATGGTCAGGGCGTTATCACTACTAAAGATAATGCTCAGTTAATATCTCTTTCTAAAGGAG
GGACGATACAAGATATTTATGTAGCCGAGGGTGATACTGTAAAAAAAGGAGAACTCCTTGCAAAGGTCGTTAACCTTGAT
CTGCAAAAAGAATATCAAAGGTATAGAACTCAAAAAGGGTATCTGGATAAAGATGTTAACGAAATATCTTTCATTCTTGA
TAAAGAAAATGAGAGTGGGTTGATTACCCTGGATGGCACCCGTTCTTTAAGCAATAAAGAGGTAAAAGCGAATATTGAAT
TAGTGCATAGTCAGATAAGAGCTAAAGAGTTAAAAAAAACCTCTCTTGATTCTGAGATTAGCGGATTACAAGAGAAGCTG
AGTTCGAAAGAAAAAGAACTCGCATTGCTTGCCGAAGAAATAAATATTCTTTCCCCACTGGTAAAAAAAGGAATTAGCCC
ATATACCAATTTTCTTAACAAGAAACAGGCGTATATAAAAGTTAAGTCTGAAATTAATGATATTGAAAGTAGCATCACTT
TAAAAAAAGATGATATTGAGTTGGTTGTTAATGATATTGAGGCGCTTAATAATGAATTGCGACTATCTTTATCTAAAATA
ATATCTAAAAATCTTCAGGAACTTGAGGTTGTTAACTCTACATTAAAAGTAATAGAGAAGCAGATAAATGAGGAGGATAT
CTATTCACCGGTTGACGGTGTAATTTATAAAATCAATAAAAGTGCCACTACTCATGGTGGTGTGATTCAGGCGGCGGACT
TACTTTTTGAAATAAAACCAAAAGTAAGGACTATGCTGGCCGATGTGAAAATATTACCCAAATACCGTGACCAAATATAT
GTAGATGAAGCCGTTAAACTGGATGTGCAGTCAATTATCCAACCAAAGATAAAATCGTATAATGCGACTATCGATAATAT
TAGCCCTGATTCCTATGAGGAAAATACCGGAGGAACAATTCAGCGTTATTATAAAGTAATTATTGCATTCGATGTTAATG
AAGATGATTTACGGTGGTTAAAACCAGGTATGACTGTTGACGCCAGTGTAATTACCGGAAAACACAGCATTATGGAATAC
CTGTTATCTCCCTTGATGAAAGGCGTGGACAAAGCCTTTTCAGAACCAGTTAATACTAAACGATTAGATACACCTTGA

Upstream 100 bases:

>100_bases
AATATAGCCTGTATATTTTAAAGCTACAGCAACTCTCATTGATTTTTCATTTAATGGATTATTTAAAAGGAAATACTGAA
AGTGAGTTAAATGTAATGAA

Downstream 100 bases:

>100_bases
GAGTGAATATAATATTATGGGAAATAAAAGCATACAAAAGTTTTTTGCCGATCAAAATTCTGTAATTGATTTATCTTCTT
TGGGTAATGCCAAAGGCGCA

Product: cation efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MNRRQSDHLMMIIISLTILIIILTYFIEINSVVHGQGVITTKDNAQLISLSKGGTIQDIYVAEGDTVKKGELLAKVVNLD
LQKEYQRYRTQKGYLDKDVNEISFILDKENESGLITLDGTRSLSNKEVKANIELVHSQIRAKELKKTSLDSEISGLQEKL
SSKEKELALLAEEINILSPLVKKGISPYTNFLNKKQAYIKVKSEINDIESSITLKKDDIELVVNDIEALNNELRLSLSKI
ISKNLQELEVVNSTLKVIEKQINEEDIYSPVDGVIYKINKSATTHGGVIQAADLLFEIKPKVRTMLADVKILPKYRDQIY
VDEAVKLDVQSIIQPKIKSYNATIDNISPDSYEENTGGTIQRYYKVIIAFDVNEDDLRWLKPGMTVDASVITGKHSIMEY
LLSPLMKGVDKAFSEPVNTKRLDTP

Sequences:

>Translated_425_residues
MNRRQSDHLMMIIISLTILIIILTYFIEINSVVHGQGVITTKDNAQLISLSKGGTIQDIYVAEGDTVKKGELLAKVVNLD
LQKEYQRYRTQKGYLDKDVNEISFILDKENESGLITLDGTRSLSNKEVKANIELVHSQIRAKELKKTSLDSEISGLQEKL
SSKEKELALLAEEINILSPLVKKGISPYTNFLNKKQAYIKVKSEINDIESSITLKKDDIELVVNDIEALNNELRLSLSKI
ISKNLQELEVVNSTLKVIEKQINEEDIYSPVDGVIYKINKSATTHGGVIQAADLLFEIKPKVRTMLADVKILPKYRDQIY
VDEAVKLDVQSIIQPKIKSYNATIDNISPDSYEENTGGTIQRYYKVIIAFDVNEDDLRWLKPGMTVDASVITGKHSIMEY
LLSPLMKGVDKAFSEPVNTKRLDTP
>Mature_425_residues
MNRRQSDHLMMIIISLTILIIILTYFIEINSVVHGQGVITTKDNAQLISLSKGGTIQDIYVAEGDTVKKGELLAKVVNLD
LQKEYQRYRTQKGYLDKDVNEISFILDKENESGLITLDGTRSLSNKEVKANIELVHSQIRAKELKKTSLDSEISGLQEKL
SSKEKELALLAEEINILSPLVKKGISPYTNFLNKKQAYIKVKSEINDIESSITLKKDDIELVVNDIEALNNELRLSLSKI
ISKNLQELEVVNSTLKVIEKQINEEDIYSPVDGVIYKINKSATTHGGVIQAADLLFEIKPKVRTMLADVKILPKYRDQIY
VDEAVKLDVQSIIQPKIKSYNATIDNISPDSYEENTGGTIQRYYKVIIAFDVNEDDLRWLKPGMTVDASVITGKHSIMEY
LLSPLMKGVDKAFSEPVNTKRLDTP

Specific function: Involved in the secretion of proteases A, B, C and G [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47873; Mature: 47873

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRRQSDHLMMIIISLTILIIILTYFIEINSVVHGQGVITTKDNAQLISLSKGGTIQDIY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEECCCCEEEEECCCCCEEEEE
VAEGDTVKKGELLAKVVNLDLQKEYQRYRTQKGYLDKDVNEISFILDKENESGLITLDGT
EECCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEECCC
RSLSNKEVKANIELVHSQIRAKELKKTSLDSEISGLQEKLSSKEKELALLAEEINILSPL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
VKKGISPYTNFLNKKQAYIKVKSEINDIESSITLKKDDIELVVNDIEALNNELRLSLSKI
HHCCCCHHHHHHCCHHHEEEEHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHH
ISKNLQELEVVNSTLKVIEKQINEEDIYSPVDGVIYKINKSATTHGGVIQAADLLFEIKP
HHCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCH
KVRTMLADVKILPKYRDQIYVDEAVKLDVQSIIQPKIKSYNATIDNISPDSYEENTGGTI
HHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHH
QRYYKVIIAFDVNEDDLRWLKPGMTVDASVITGKHSIMEYLLSPLMKGVDKAFSEPVNTK
HHEEEEEEEEECCCCCHHHCCCCCEEEHHEECCHHHHHHHHHHHHHHHHHHHHCCCCCCC
RLDTP
CCCCC
>Mature Secondary Structure
MNRRQSDHLMMIIISLTILIIILTYFIEINSVVHGQGVITTKDNAQLISLSKGGTIQDIY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEECCCCEEEEECCCCCEEEEE
VAEGDTVKKGELLAKVVNLDLQKEYQRYRTQKGYLDKDVNEISFILDKENESGLITLDGT
EECCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEECCC
RSLSNKEVKANIELVHSQIRAKELKKTSLDSEISGLQEKLSSKEKELALLAEEINILSPL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
VKKGISPYTNFLNKKQAYIKVKSEINDIESSITLKKDDIELVVNDIEALNNELRLSLSKI
HHCCCCHHHHHHCCHHHEEEEHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHH
ISKNLQELEVVNSTLKVIEKQINEEDIYSPVDGVIYKINKSATTHGGVIQAADLLFEIKP
HHCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCH
KVRTMLADVKILPKYRDQIYVDEAVKLDVQSIIQPKIKSYNATIDNISPDSYEENTGGTI
HHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHH
QRYYKVIIAFDVNEDDLRWLKPGMTVDASVITGKHSIMEYLLSPLMKGVDKAFSEPVNTK
HHEEEEEEEEECCCCCHHHCCCCCEEEHHEECCHHHHHHHHHHHHHHHHHHHHCCCCCCC
RLDTP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2184029 [H]