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The map label for this gene is argC [H]

Identifier: 16767386

GI number: 16767386

Start: 4339513

End: 4340517

Strand: Direct

Name: argC [H]

Synonym: STM4121

Alternate gene names: 16767386

Gene position: 4339513-4340517 (Clockwise)

Preceding gene: 16767381

Following gene: 161353577

Centisome position: 89.34

GC content: 53.93

Gene sequence:

>1005_bases
ATGTTGAATACGCTGATTGTAGGCGCTAGCGGTTATGCGGGCGCAGAGCTTGTAAGCTACGTAAATCGCCACCCACATAT
GACCATAACCGCTTTGACCGTCTCAGCGCAAAGCAATGATGCAGGAAAGTTAATTTCTGATTTACATCCGCAGTTAAAAG
GGATTGTCGACCTGCCATTGCAACCGATGTCGGATGTACGTGACTTTAGCGCAGATGTTGATGTGGTGTTCCTGGCGACA
GCGCATGAAGTGAGCCACGATCTGGCGCCGCAATTTTTACAGGCCGGATGCGTCGTATTCGATCTTTCCGGCGCGTTTCG
GGTAAACGATCGCGCCTTCTATGAAAAGTATTACGGATTTACTCATCAGTATCCTGAGCTGCTGGAGCAGGCGGTGTACG
GTCTGGCGGAGTGGAATGTCGATAAACTGAACACGGCGAATCTGATTGCGGTTCCTGGTTGCTATCCAACCGCAGCGCAG
TTGTCGCTAAAACCGCTGATTGACGGCGGGCTTCTCGATCTGACGCAGTGGCCGGTAATTAATGCCACCAGCGGGGTGAG
CGGCGCGGGGCGCAAGGCGGCAATATCGAACAGTTTCTGTGAAGTGAGTTTGCAACCGTATGGCGTGTTTACGCATCGTC
ATCAGCCGGAAATCGCCGTCCATCTGGGCGCGGAGGTCATCTTCACCCCGCATCTGGGGAATTTCCCGCGCGGGATTCTG
GAAACCATTACCTGCCGCCTGAAAGCGGGAGTAACCCATGCGCAGGTCGCCGACGTGTTGCAAAAAGCCTATGGCGACAA
ACCGCTGGTGCGCCTGTATGACAAAGGCGTTCCGGCGTTAAAGAACGTCGTCGGGCTGCCGTTCTGCGATATTGGTTTTG
CCGTCCAGGGCGAACATCTGATTGTGGTGGCAACCGAAGACAACTTGTTGAAAGGCGCAGCGGCGCAGGCGGTGCAGTGC
GCTAATATTCGTTTTGGCTTCGCTGAAACGCAGTCTCTTATTTAA

Upstream 100 bases:

>100_bases
AACGTTTTTCATTGTTGACACACCTCAGGTCATGATAGTATCAATATTCATGCATTAATTATGAATAAAAATACATTAAC
GTTGAGCATAAAGGAACCCG

Downstream 100 bases:

>100_bases
GGGTGAAATGATGAATCCATTAATTATCAAGCTGGGTGGCGTATTACTGGATAGCGAAGAGGCTCTGGAACGTCTTTTTA
CCGCGCTGGTCAACTATCGT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MLNTLIVGASGYAGAELVSYVNRHPHMTITALTVSAQSNDAGKLISDLHPQLKGIVDLPLQPMSDVRDFSADVDVVFLAT
AHEVSHDLAPQFLQAGCVVFDLSGAFRVNDRAFYEKYYGFTHQYPELLEQAVYGLAEWNVDKLNTANLIAVPGCYPTAAQ
LSLKPLIDGGLLDLTQWPVINATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEIAVHLGAEVIFTPHLGNFPRGIL
ETITCRLKAGVTHAQVADVLQKAYGDKPLVRLYDKGVPALKNVVGLPFCDIGFAVQGEHLIVVATEDNLLKGAAAQAVQC
ANIRFGFAETQSLI

Sequences:

>Translated_334_residues
MLNTLIVGASGYAGAELVSYVNRHPHMTITALTVSAQSNDAGKLISDLHPQLKGIVDLPLQPMSDVRDFSADVDVVFLAT
AHEVSHDLAPQFLQAGCVVFDLSGAFRVNDRAFYEKYYGFTHQYPELLEQAVYGLAEWNVDKLNTANLIAVPGCYPTAAQ
LSLKPLIDGGLLDLTQWPVINATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEIAVHLGAEVIFTPHLGNFPRGIL
ETITCRLKAGVTHAQVADVLQKAYGDKPLVRLYDKGVPALKNVVGLPFCDIGFAVQGEHLIVVATEDNLLKGAAAQAVQC
ANIRFGFAETQSLI
>Mature_334_residues
MLNTLIVGASGYAGAELVSYVNRHPHMTITALTVSAQSNDAGKLISDLHPQLKGIVDLPLQPMSDVRDFSADVDVVFLAT
AHEVSHDLAPQFLQAGCVVFDLSGAFRVNDRAFYEKYYGFTHQYPELLEQAVYGLAEWNVDKLNTANLIAVPGCYPTAAQ
LSLKPLIDGGLLDLTQWPVINATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEIAVHLGAEVIFTPHLGNFPRGIL
ETITCRLKAGVTHAQVADVLQKAYGDKPLVRLYDKGVPALKNVVGLPFCDIGFAVQGEHLIVVATEDNLLKGAAAQAVQC
ANIRFGFAETQSLI

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=334, Percent_Identity=91.0179640718563, Blast_Score=610, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6320913, Length=338, Percent_Identity=30.4733727810651, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 35950; Mature: 35950

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTLIVGASGYAGAELVSYVNRHPHMTITALTVSAQSNDAGKLISDLHPQLKGIVDLPL
CCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHCHHHHCEECCCC
QPMSDVRDFSADVDVVFLATAHEVSHDLAPQFLQAGCVVFDLSGAFRVNDRAFYEKYYGF
CCHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCEEEEECCCCEEECCHHHHHHHCCC
THQYPELLEQAVYGLAEWNVDKLNTANLIAVPGCYPTAAQLSLKPLIDGGLLDLTQWPVI
CCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHCEEEEECCCCCEEECCCCCEE
NATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEIAVHLGAEVIFTPHLGNFPRGIL
ECCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCCEEEEECCEEEEECCCCCCCHHHH
ETITCRLKAGVTHAQVADVLQKAYGDKPLVRLYDKGVPALKNVVGLPFCDIGFAVQGEHL
HHHHHHHHCCCCHHHHHHHHHHHHCCCCEEHHHHCCCHHHHHHHCCCEECCCEEECCCEE
IVVATEDNLLKGAAAQAVQCANIRFGFAETQSLI
EEEECCCCHHHHHHHHHEEECCEEECCHHHHCCC
>Mature Secondary Structure
MLNTLIVGASGYAGAELVSYVNRHPHMTITALTVSAQSNDAGKLISDLHPQLKGIVDLPL
CCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHCHHHHCEECCCC
QPMSDVRDFSADVDVVFLATAHEVSHDLAPQFLQAGCVVFDLSGAFRVNDRAFYEKYYGF
CCHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCEEEEECCCCEEECCHHHHHHHCCC
THQYPELLEQAVYGLAEWNVDKLNTANLIAVPGCYPTAAQLSLKPLIDGGLLDLTQWPVI
CCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHCEEEEECCCCCEEECCCCCEE
NATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEIAVHLGAEVIFTPHLGNFPRGIL
ECCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCCEEEEECCEEEEECCCCCCCHHHH
ETITCRLKAGVTHAQVADVLQKAYGDKPLVRLYDKGVPALKNVVGLPFCDIGFAVQGEHL
HHHHHHHHCCCCHHHHHHHHHHHHCCCCEEHHHHCCCHHHHHHHCCCEECCCEEECCCEE
IVVATEDNLLKGAAAQAVQCANIRFGFAETQSLI
EEEECCCCHHHHHHHHHEEECCEEECCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]