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The map label for this gene is frwD [H]

Identifier: 16767381

GI number: 16767381

Start: 4331957

End: 4332310

Strand: Direct

Name: frwD [H]

Synonym: STM4116

Alternate gene names: 16767381

Gene position: 4331957-4332310 (Clockwise)

Preceding gene: 16767380

Following gene: 16767386

Centisome position: 89.18

GC content: 56.5

Gene sequence:

>354_bases
ATGGCAGTACCTGTACGGCATCTGGTGGCAGTGACCGCCTGCGTGAGCGGTGTAGCGCATACCTATATGGCTGCTGAACG
GCTGGAAAAACTTTGCCAGCAGGAGAAGTGGAGCATCAAGATTGAAACCCAGGGGGCACTCGGTACAGAGAACCGCTTAA
CGGAAGAGGATATCCGCCGTGCCGATGTCGTGTTGCTCATTACCGATATCGAGCTGGCGGGCGTGGAGCGATTTACCCGG
AGTCGCTATGTCCAGTCGGGGATCAGCGCTTTTTTGCGGGAGCCACAGCGGGTAATGAGCGCTGTGCGTAAACTCCTTTC
CGCGCCGCAACATACCCACCTTATCCTGGAGTAA

Upstream 100 bases:

>100_bases
TGGATGATGAAAGATATTCCCGCGCCGTCGGTGCAAGAGATCGCTCTGTTTCGGGAGATGGCGGAGCAAGCAGGATTTCA
GGTCACCACAGGAGGTTAAT

Downstream 100 bases:

>100_bases
TCTGCTTTTCCGTTAGCTGGCTGTGATACTGGCGGCGATACTCCGACGGCGAGCGTTCCGTATTTTTGCGAAACAGGCGG
CAGAAATAGTTACTGTCGAC

Product: fructose-like phosphotransferase EIIB subunit 3

Products: NA

Alternate protein names: PTS system fructose-like EIIB component 3 [H]

Number of amino acids: Translated: 117; Mature: 116

Protein sequence:

>117_residues
MAVPVRHLVAVTACVSGVAHTYMAAERLEKLCQQEKWSIKIETQGALGTENRLTEEDIRRADVVLLITDIELAGVERFTR
SRYVQSGISAFLREPQRVMSAVRKLLSAPQHTHLILE

Sequences:

>Translated_117_residues
MAVPVRHLVAVTACVSGVAHTYMAAERLEKLCQQEKWSIKIETQGALGTENRLTEEDIRRADVVLLITDIELAGVERFTR
SRYVQSGISAFLREPQRVMSAVRKLLSAPQHTHLILE
>Mature_116_residues
AVPVRHLVAVTACVSGVAHTYMAAERLEKLCQQEKWSIKIETQGALGTENRLTEEDIRRADVVLLITDIELAGVERFTRS
RYVQSGISAFLREPQRVMSAVRKLLSAPQHTHLILE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG1445

COG function: function code G; Phosphotransferase system fructose-specific component IIB

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790390, Length=111, Percent_Identity=83.7837837837838, Blast_Score=190, Evalue=2e-50,
Organism=Escherichia coli, GI1790387, Length=100, Percent_Identity=46, Blast_Score=95, Evalue=1e-21,
Organism=Escherichia coli, GI87082348, Length=95, Percent_Identity=42.1052631578947, Blast_Score=75, Evalue=1e-15,
Organism=Escherichia coli, GI1788492, Length=97, Percent_Identity=38.1443298969072, Blast_Score=72, Evalue=8e-15,
Organism=Escherichia coli, GI1788730, Length=106, Percent_Identity=30.188679245283, Blast_Score=65, Evalue=9e-13,
Organism=Escherichia coli, GI1786951, Length=71, Percent_Identity=42.2535211267606, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003353 [H]

Pfam domain/function: PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 13153; Mature: 13022

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVPVRHLVAVTACVSGVAHTYMAAERLEKLCQQEKWSIKIETQGALGTENRLTEEDIRR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHH
ADVVLLITDIELAGVERFTRSRYVQSGISAFLREPQRVMSAVRKLLSAPQHTHLILE
HCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEECC
>Mature Secondary Structure 
AVPVRHLVAVTACVSGVAHTYMAAERLEKLCQQEKWSIKIETQGALGTENRLTEEDIRR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHH
ADVVLLITDIELAGVERFTRSRYVQSGISAFLREPQRVMSAVRKLLSAPQHTHLILE
HCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7773398 [H]