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The map label for this gene is ydeV [H]

Identifier: 16767338

GI number: 16767338

Start: 4280606

End: 4282198

Strand: Reverse

Name: ydeV [H]

Synonym: STM4072

Alternate gene names: 16767338

Gene position: 4282198-4280606 (Counterclockwise)

Preceding gene: 16767339

Following gene: 16767337

Centisome position: 88.16

GC content: 54.99

Gene sequence:

>1593_bases
ATGGCTCGACTCTGTACCCATACTGAATCAGGACATTACCTGATGGCTCTTGACGCCGGTACCGGTAGCGTCAGAGCAGT
AATTTTTGATCTACAAGGAAAGCAAATAGCTGTCGGTCAAGCGGAATGGCAGCATCTGGCCGTGCCGGATGTGCCTGGTT
CGATGGAGTTTGATCTTGCCAAAAACTGGCAACTGGCTTGCCAGTGTATCCGTCAGGCACTACAGAAAGCCGCCATCCCT
GCAACGGCTATCGCTGCCGTATCGGCCTGCTCGATGCGTGAAGGCATTGTTATTTATGACAGTAACGGCGAACCAATTTG
GGCCTGCGCTAATGTTGACGCCCGCGCGGCGCACGAAGTCAGTGAATTAAAAGAGCTGTACGATAACACCTTTGAGGAGG
AAGTTTATCGTTGCTCCGGGCAAACGCTGGCGCTCAGCGCTATTCCGCGTCTGCTCTGGCTTGCCCACCATCGTCCGGAT
ATTTATCATCGCGCGTCAACCGTCACTATGATCAGCGACTGGATGGCCTTTATGCTCAGCGGCGAACTGGCGGTCGATCC
CTCCAACGCAGGCACGACGGGGTTATTGGATCTGGTGACCCGCAACTGGAAACGTAGTCTGTTACAGATGGCGGGCCTGC
GTTCTGACATTCTCTCGCCGGTAAAAGAAACCGGGACGCTGCTCGGTCACATTTCACAGAAAGCGGCTGAACAGTGCGAC
CTGCAAGCGGGTACGCCGGTCATCGTTGGCGGCGGCGATGTGCAGTTAGGCTGTCTGGGGCTGGGCGTCGTACGCCCGGC
GCAAACGGCCGTGCTGGGCGGAACCTTCTGGCAACAGGTCGTCAATCTTCCCGCGCCGGTCACCGACCCAAACATGAACG
TTCGCATCAATCCTCATGTGATCCCCGGTATGGTACAAACCGAGTCTATTAGCTTTTTTACTGGGTTAACGATGCGTTGG
TTCCGCGACGCCTTTTGCGCCGAGGAAAAACTAATCGCTGAAAGGTTAGGTATTGATGCGTATTCCCTGCTGGAAGATAT
GGCCAGCCGGGTGCCTCCCGGCGCGTACGGTGTGATGCCCATCTTCTCTGACGTTATGCGTTTTAAACGCTGGTACCATG
CCGCGCCGTCGTTTATCAATCTGTCTATCGATCCTGAAAAGTGTAATAAAGCGACCCTATTTCGCGCGCTGGAAGAGAAT
GCCGCCATTGTTTCCGCCTGCAATTTACAGCAAATTGCCGCGTTTTCCGGCGTACAGGCCGACTCGCTGGTTTTTGCTGG
CGGAGGATCTAAAGGCAAATTATGGAGCCAAATCCTTGCCGACGTTACGGGACTCACCGTTCACGTACCTGTCGTCAAAG
AAGCTACCGCGCTAGGGTGCGCTATTGCCGCAGGCGTTGGCGTGGGTGTCTGGCCATCGCTGGCGGAAACGGGAGAAAAG
CTAGTGCGCTGGGATCGGGAGCATAAACCTAATCCTGAAAATTTCGCTGTCTATCAGCAGGCCAGAGAAAAATGGCAGGC
CGTTTATCAGGATCAACGCGCGCTGGTCGATGGTGGCTTAACGACATCCCTCTGGAAAGCGCCAGGCCTGTAA

Upstream 100 bases:

>100_bases
TATTGAAAAATAAAAAAATAAAATAACACTTACCTCAATTCAATAAACAATAACTGACAGGATTTTATGTAACGATGTAA
AAATAGCCGAGGATAAAAAA

Downstream 100 bases:

>100_bases
CAGGAGAATAAGCATGCAAAAAACGAATGAGAAGAATCATGAATACCGCTTTGGCGATAATGGCCCTAAATACTTAATCC
GTGGGCCGGGCTGCGATATG

Product: autoinducer-2 (AI-2) kinase

Products: NA

Alternate protein names: AI-2 kinase [H]

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MARLCTHTESGHYLMALDAGTGSVRAVIFDLQGKQIAVGQAEWQHLAVPDVPGSMEFDLAKNWQLACQCIRQALQKAAIP
ATAIAAVSACSMREGIVIYDSNGEPIWACANVDARAAHEVSELKELYDNTFEEEVYRCSGQTLALSAIPRLLWLAHHRPD
IYHRASTVTMISDWMAFMLSGELAVDPSNAGTTGLLDLVTRNWKRSLLQMAGLRSDILSPVKETGTLLGHISQKAAEQCD
LQAGTPVIVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLPAPVTDPNMNVRINPHVIPGMVQTESISFFTGLTMRW
FRDAFCAEEKLIAERLGIDAYSLLEDMASRVPPGAYGVMPIFSDVMRFKRWYHAAPSFINLSIDPEKCNKATLFRALEEN
AAIVSACNLQQIAAFSGVQADSLVFAGGGSKGKLWSQILADVTGLTVHVPVVKEATALGCAIAAGVGVGVWPSLAETGEK
LVRWDREHKPNPENFAVYQQAREKWQAVYQDQRALVDGGLTTSLWKAPGL

Sequences:

>Translated_530_residues
MARLCTHTESGHYLMALDAGTGSVRAVIFDLQGKQIAVGQAEWQHLAVPDVPGSMEFDLAKNWQLACQCIRQALQKAAIP
ATAIAAVSACSMREGIVIYDSNGEPIWACANVDARAAHEVSELKELYDNTFEEEVYRCSGQTLALSAIPRLLWLAHHRPD
IYHRASTVTMISDWMAFMLSGELAVDPSNAGTTGLLDLVTRNWKRSLLQMAGLRSDILSPVKETGTLLGHISQKAAEQCD
LQAGTPVIVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLPAPVTDPNMNVRINPHVIPGMVQTESISFFTGLTMRW
FRDAFCAEEKLIAERLGIDAYSLLEDMASRVPPGAYGVMPIFSDVMRFKRWYHAAPSFINLSIDPEKCNKATLFRALEEN
AAIVSACNLQQIAAFSGVQADSLVFAGGGSKGKLWSQILADVTGLTVHVPVVKEATALGCAIAAGVGVGVWPSLAETGEK
LVRWDREHKPNPENFAVYQQAREKWQAVYQDQRALVDGGLTTSLWKAPGL
>Mature_529_residues
ARLCTHTESGHYLMALDAGTGSVRAVIFDLQGKQIAVGQAEWQHLAVPDVPGSMEFDLAKNWQLACQCIRQALQKAAIPA
TAIAAVSACSMREGIVIYDSNGEPIWACANVDARAAHEVSELKELYDNTFEEEVYRCSGQTLALSAIPRLLWLAHHRPDI
YHRASTVTMISDWMAFMLSGELAVDPSNAGTTGLLDLVTRNWKRSLLQMAGLRSDILSPVKETGTLLGHISQKAAEQCDL
QAGTPVIVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLPAPVTDPNMNVRINPHVIPGMVQTESISFFTGLTMRWF
RDAFCAEEKLIAERLGIDAYSLLEDMASRVPPGAYGVMPIFSDVMRFKRWYHAAPSFINLSIDPEKCNKATLFRALEENA
AIVSACNLQQIAAFSGVQADSLVFAGGGSKGKLWSQILADVTGLTVHVPVVKEATALGCAIAAGVGVGVWPSLAETGEKL
VRWDREHKPNPENFAVYQQAREKWQAVYQDQRALVDGGLTTSLWKAPGL

Specific function: Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787789, Length=530, Percent_Identity=82.6415094339623, Blast_Score=915, Evalue=0.0,
Organism=Escherichia coli, GI1790361, Length=496, Percent_Identity=26.8145161290323, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1790005, Length=510, Percent_Identity=23.3333333333333, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1789138, Length=477, Percent_Identity=23.6897274633124, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1789168, Length=505, Percent_Identity=23.960396039604, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789987, Length=509, Percent_Identity=23.9685658153242, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17535599, Length=472, Percent_Identity=23.9406779661017, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018484 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: NA

Molecular weight: Translated: 57440; Mature: 57309

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLCTHTESGHYLMALDAGTGSVRAVIFDLQGKQIAVGQAEWQHLAVPDVPGSMEFDLA
CCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCEEEECCCCCCEEECCCCCCCCCCCCC
KNWQLACQCIRQALQKAAIPATAIAAVSACSMREGIVIYDSNGEPIWACANVDARAAHEV
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCHHHHHHH
SELKELYDNTFEEEVYRCSGQTLALSAIPRLLWLAHHRPDIYHRASTVTMISDWMAFMLS
HHHHHHHHCHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
GELAVDPSNAGTTGLLDLVTRNWKRSLLQMAGLRSDILSPVKETGTLLGHISQKAAEQCD
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LQAGTPVIVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLPAPVTDPNMNVRINPHV
CCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
IPGMVQTESISFFTGLTMRWFRDAFCAEEKLIAERLGIDAYSLLEDMASRVPPGAYGVMP
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHH
IFSDVMRFKRWYHAAPSFINLSIDPEKCNKATLFRALEENAAIVSACNLQQIAAFSGVQA
HHHHHHHHHHHHHCCCCEEEEEECHHHCCHHHHHHHHHCCCCEEECCCHHHHHHHCCCCC
DSLVFAGGGSKGKLWSQILADVTGLTVHVPVVKEATALGCAIAAGVGVGVWPSLAETGEK
CCEEEECCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LVRWDREHKPNPENFAVYQQAREKWQAVYQDQRALVDGGLTTSLWKAPGL
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCC
>Mature Secondary Structure 
ARLCTHTESGHYLMALDAGTGSVRAVIFDLQGKQIAVGQAEWQHLAVPDVPGSMEFDLA
CCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCEEEECCCCCCEEECCCCCCCCCCCCC
KNWQLACQCIRQALQKAAIPATAIAAVSACSMREGIVIYDSNGEPIWACANVDARAAHEV
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCHHHHHHH
SELKELYDNTFEEEVYRCSGQTLALSAIPRLLWLAHHRPDIYHRASTVTMISDWMAFMLS
HHHHHHHHCHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
GELAVDPSNAGTTGLLDLVTRNWKRSLLQMAGLRSDILSPVKETGTLLGHISQKAAEQCD
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LQAGTPVIVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLPAPVTDPNMNVRINPHV
CCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
IPGMVQTESISFFTGLTMRWFRDAFCAEEKLIAERLGIDAYSLLEDMASRVPPGAYGVMP
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHH
IFSDVMRFKRWYHAAPSFINLSIDPEKCNKATLFRALEENAAIVSACNLQQIAAFSGVQA
HHHHHHHHHHHHHCCCCEEEEEECHHHCCHHHHHHHHHCCCCEEECCCHHHHHHHCCCCC
DSLVFAGGGSKGKLWSQILADVTGLTVHVPVVKEATALGCAIAAGVGVGVWPSLAETGEK
CCEEEECCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LVRWDREHKPNPENFAVYQQAREKWQAVYQDQRALVDGGLTTSLWKAPGL
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA