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The map label for this gene is aslB [H]

Identifier: 16767236

GI number: 16767236

Start: 4172370

End: 4173713

Strand: Direct

Name: aslB [H]

Synonym: STM3966

Alternate gene names: 16767236

Gene position: 4172370-4173713 (Clockwise)

Preceding gene: 16767235

Following gene: 16767238

Centisome position: 85.9

GC content: 53.72

Gene sequence:

>1344_bases
TTGTCTCATGGCGCTGGTGAACCTTATTTTTTAACGGAGATGTCTGACATGGCGGTAGCAGGTTGTCACGTAATGGCCAA
ACCCGGCGGCGCGATCTGCAATATTGATTGCACATATTGCTTCTATCTTGAAAAAGAGGCGCTGTACCCGGAACGCAATA
AAAACTGGCGGATGTCGGACGAGACGCTGGAACAATTTATACGCCAGCATATTGCCGCGCAGAGTGGCGACCGCATTGAC
TTTGCCTGGCAGGGCGGCGAACCGACCATGATGGGGCTACCGTTTTTCCGTCGGGTTGTCGCATTATGTGAAAAGTACGG
CGATGGGCGAAAAATCACTCATGCGTTGCAGACGAACGGCATCCTGGTGAATGACGAGTGGGCGCGCTTTTTCGCTGAAC
AGCATTTTCTCATCGGTCTCTCTATCGACGGCCCGGCGTCGTTACACAACCACTATCGGTTTAATCGCGCTGGAAAAGGA
ACTCATGAACAGGTCGTCGCAGCCATGGCGCGGCTTAAAGCGCACCATGTCGACTTTAATACCTTAACCGTCGTGGGAAA
ACATAACGTCGGTCATGCAGCAGACGTCTACGAATTTCTTCTGGCGGCGGGATCGCGTTTTATTCAGTTTATCCCGCTGG
TAGAGCGAATGAGCACCGATAACTCATCGGTACTTAATCTGGTGATGCCCGGCGAAAGCGCGGCGACGCTGGCGCCATGG
ACGGTACCGTCGTGGCAATATGGCGAATTTCTCAACCAGATCTTTGATATCTGGGTTCGTCGCGACGTAGACCGCGTCTA
TGTGCAGATGTTTGACGTGGCGTTAGCCGCCTGGACGGCGCAGCAGCCGGTACTGTGTGTACATTCCGAGACTTGTGGAC
ATGCCTTCGCGTTGGAGTCGAACGGCGATCTCTACAACTGCGACCACTTTGTCTACCCGGAGCATCTGCTGGGAAATATC
CACCAGCACAGCATCAAAGCCTTAAATAATAGCGAGCGGGCTATTGCCTTTGGCGAGGCCAAGCGGGAGACCCTGACCGC
CGATTGTCGTCGCTGTGACTACCGCTTTGTATGTCATGGCGGCTGTCCTAAGCATCGCTTTGCCGTCTCGCCGTCTGGTC
ATCCTGCGCATAATTACTTGTGTGCGGGCTATAAGCATTTTTTCCAGCACGTTACGCCGTATATGAATGTCTGGCGGGAG
CTGCTGGCGCAAGGCTATCCGATGGCATCGATCATGCGCTGGCTGGCGCAGGACGCGCGTAAAGACACAGGAGCCGTCAG
TCGTAACCATCCCTGTCCCTGCGGCAGCGGCAAAAAATATAAAAAATGCTGTGGTAAAGCATAG

Upstream 100 bases:

>100_bases
CCTCGCAGATCGTTTTTCCTGTCATGATCGCCCAGCGCTCTCATAGCACAAAACGAGGTTTTCCATTCTGTTATGTTCCC
TGGCGACGATAAACGTCGCA

Downstream 100 bases:

>100_bases
CTAACGTGGCGATGACGCTTTGTTGAGCCTACACCGACTCCGGTCTCGTAGGCCCAACAAACATCGTAATGCGCTGTGGT
TAGCCTTTTTTCCCACCGTA

Product: arylsulfatase regulator

Products: NA

Alternate protein names: AnSME homolog [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSHGAGEPYFLTEMSDMAVAGCHVMAKPGGAICNIDCTYCFYLEKEALYPERNKNWRMSDETLEQFIRQHIAAQSGDRID
FAWQGGEPTMMGLPFFRRVVALCEKYGDGRKITHALQTNGILVNDEWARFFAEQHFLIGLSIDGPASLHNHYRFNRAGKG
THEQVVAAMARLKAHHVDFNTLTVVGKHNVGHAADVYEFLLAAGSRFIQFIPLVERMSTDNSSVLNLVMPGESAATLAPW
TVPSWQYGEFLNQIFDIWVRRDVDRVYVQMFDVALAAWTAQQPVLCVHSETCGHAFALESNGDLYNCDHFVYPEHLLGNI
HQHSIKALNNSERAIAFGEAKRETLTADCRRCDYRFVCHGGCPKHRFAVSPSGHPAHNYLCAGYKHFFQHVTPYMNVWRE
LLAQGYPMASIMRWLAQDARKDTGAVSRNHPCPCGSGKKYKKCCGKA

Sequences:

>Translated_447_residues
MSHGAGEPYFLTEMSDMAVAGCHVMAKPGGAICNIDCTYCFYLEKEALYPERNKNWRMSDETLEQFIRQHIAAQSGDRID
FAWQGGEPTMMGLPFFRRVVALCEKYGDGRKITHALQTNGILVNDEWARFFAEQHFLIGLSIDGPASLHNHYRFNRAGKG
THEQVVAAMARLKAHHVDFNTLTVVGKHNVGHAADVYEFLLAAGSRFIQFIPLVERMSTDNSSVLNLVMPGESAATLAPW
TVPSWQYGEFLNQIFDIWVRRDVDRVYVQMFDVALAAWTAQQPVLCVHSETCGHAFALESNGDLYNCDHFVYPEHLLGNI
HQHSIKALNNSERAIAFGEAKRETLTADCRRCDYRFVCHGGCPKHRFAVSPSGHPAHNYLCAGYKHFFQHVTPYMNVWRE
LLAQGYPMASIMRWLAQDARKDTGAVSRNHPCPCGSGKKYKKCCGKA
>Mature_446_residues
SHGAGEPYFLTEMSDMAVAGCHVMAKPGGAICNIDCTYCFYLEKEALYPERNKNWRMSDETLEQFIRQHIAAQSGDRIDF
AWQGGEPTMMGLPFFRRVVALCEKYGDGRKITHALQTNGILVNDEWARFFAEQHFLIGLSIDGPASLHNHYRFNRAGKGT
HEQVVAAMARLKAHHVDFNTLTVVGKHNVGHAADVYEFLLAAGSRFIQFIPLVERMSTDNSSVLNLVMPGESAATLAPWT
VPSWQYGEFLNQIFDIWVRRDVDRVYVQMFDVALAAWTAQQPVLCVHSETCGHAFALESNGDLYNCDHFVYPEHLLGNIH
QHSIKALNNSERAIAFGEAKRETLTADCRRCDYRFVCHGGCPKHRFAVSPSGHPAHNYLCAGYKHFFQHVTPYMNVWREL
LAQGYPMASIMRWLAQDARKDTGAVSRNHPCPCGSGKKYKKCCGKA

Specific function: Potential Positive Factor For The Regulation Of Arylsulfatase. [C]

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994973, Length=393, Percent_Identity=47.8371501272265, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI87081923, Length=392, Percent_Identity=41.8367346938776, Blast_Score=340, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 50357; Mature: 50226

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHGAGEPYFLTEMSDMAVAGCHVMAKPGGAICNIDCTYCFYLEKEALYPERNKNWRMSD
CCCCCCCCEEEECHHHHHHCCEEEEECCCCCEEEEEEEEEEEEEHHCCCCCCCCCCCCCH
ETLEQFIRQHIAAQSGDRIDFAWQGGEPTMMGLPFFRRVVALCEKYGDGRKITHALQTNG
HHHHHHHHHHHHHCCCCEEEEEEECCCCCEECCHHHHHHHHHHHHCCCCCCEEHHHHCCC
ILVNDEWARFFAEQHFLIGLSIDGPASLHNHYRFNRAGKGTHEQVVAAMARLKAHHVDFN
EEECHHHHHHHHCCEEEEEEECCCCHHHHHCEEECCCCCCHHHHHHHHHHHHHHHCCCCC
TLTVVGKHNVGHAADVYEFLLAAGSRFIQFIPLVERMSTDNSSVLNLVMPGESAATLAPW
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCC
TVPSWQYGEFLNQIFDIWVRRDVDRVYVQMFDVALAAWTAQQPVLCVHSETCGHAFALES
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECC
NGDLYNCDHFVYPEHLLGNIHQHSIKALNNSERAIAFGEAKRETLTADCRRCDYRFVCHG
CCCEECCCCCCCHHHHHCCHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCEEEEECC
GCPKHRFAVSPSGHPAHNYLCAGYKHFFQHVTPYMNVWRELLAQGYPMASIMRWLAQDAR
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KDTGAVSRNHPCPCGSGKKYKKCCGKA
HCCCCCCCCCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
SHGAGEPYFLTEMSDMAVAGCHVMAKPGGAICNIDCTYCFYLEKEALYPERNKNWRMSD
CCCCCCCEEEECHHHHHHCCEEEEECCCCCEEEEEEEEEEEEEHHCCCCCCCCCCCCCH
ETLEQFIRQHIAAQSGDRIDFAWQGGEPTMMGLPFFRRVVALCEKYGDGRKITHALQTNG
HHHHHHHHHHHHHCCCCEEEEEEECCCCCEECCHHHHHHHHHHHHCCCCCCEEHHHHCCC
ILVNDEWARFFAEQHFLIGLSIDGPASLHNHYRFNRAGKGTHEQVVAAMARLKAHHVDFN
EEECHHHHHHHHCCEEEEEEECCCCHHHHHCEEECCCCCCHHHHHHHHHHHHHHHCCCCC
TLTVVGKHNVGHAADVYEFLLAAGSRFIQFIPLVERMSTDNSSVLNLVMPGESAATLAPW
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCC
TVPSWQYGEFLNQIFDIWVRRDVDRVYVQMFDVALAAWTAQQPVLCVHSETCGHAFALES
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECC
NGDLYNCDHFVYPEHLLGNIHQHSIKALNNSERAIAFGEAKRETLTADCRRCDYRFVCHG
CCCEECCCCCCCHHHHHCCHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCEEEEECC
GCPKHRFAVSPSGHPAHNYLCAGYKHFFQHVTPYMNVWRELLAQGYPMASIMRWLAQDAR
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KDTGAVSRNHPCPCGSGKKYKKCCGKA
HCCCCCCCCCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503; 11222759 [H]