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The map label for this gene is ycbL [C]

Identifier: 16767022

GI number: 16767022

Start: 3929410

End: 3930291

Strand: Direct

Name: ycbL [C]

Synonym: STM3737

Alternate gene names: 16767022

Gene position: 3929410-3930291 (Clockwise)

Preceding gene: 16767020

Following gene: 16767023

Centisome position: 80.89

GC content: 51.7

Gene sequence:

>882_bases
ATGAATCGCTATGCATTATTCCTTGTATGTATATTTTCAACATCAGCACTTCCTGCCATGGCGGCATTAGATCCTTCACA
ACCGTTATCACCCGCGCCTCCGTTATCACTGTTTAAAGCGTGGGCTAAGCCTATAAAGCCGTTTCAAATCACAGAAGGCG
TGTGGTATGTCGGTACGAAAAATCTCTCTTCTATTCTGCTGACCACTCCGGCAGGGCATATTCTTATTGATGCGGGGTTG
GATGAAAGCGCACCGCAAATTAAAGCGAATATTGAAGCGGCAGGATTCCGCCTCACAGACGTGCGCTATCTGTTGAATAG
CCATGCGCGGCTGGATCAAGCGGGGGGCATGGCACGTTTGAAAGCGTGGAGCGGCGCACAATTGGTCGCCAGCCAACCCA
ACGCCGATCAGATGGCGAGGGGTGGACGACAGGATTTTGCGCTTGGCGATGCGCTCCCCTTTCCGCCCGTCACCACCGAT
AAAATTATCCACCACCAGGAAAGCATCATCCTCGGAGGGATAACCGTGACAGCACTATTCACGCCTGGACATCTGCCCGG
CTCAACTTCCTGGCGCGTAACGCTCCGCAACGGCAAGACGCTAATTTACGCAGATAGTCTCGCCACGCCCGACTATCTGC
TGATTAACAACAAAAATTACCCTGACCTGGTTACTGATATTCAGAGCAGCTTTAAGACACTGGCCGCCCAGCATGTTGAT
ATCTTTATTGCCAACAAAGGTGACCGCTTCGGGCTACTGGAGAAACGACAGCAACTTCGCAACGGCGATACACAGGCATT
CTTTGATTCCAATGGCTTGCAACAGTATGTGGAACGCTCGCGCCAGCGCTTCATCACACAACTTACCGCACAGCAGCCAT
AA

Upstream 100 bases:

>100_bases
GTTCATATCCATTTGCAGCAAGTTCATTAAACGTCTCTCTTATTGAACCTGGCTAAATTACTGCCAGGTATACTGCGGGC
GCTTCAATCAGGAGAACATT

Downstream 100 bases:

>100_bases
TGAAATAACTCACCGGCGGCGCGTCCAGGGCGCCGTTCTTTTAAATTATCTAAGTCAAAATAGAAAAACCTCGCATACAA
TAAACCACAAAAATGATGTT

Product: Zn-dependent hydrolase

Products: NA

Alternate protein names: Beta-lactamase type II; Penicillinase [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNRYALFLVCIFSTSALPAMAALDPSQPLSPAPPLSLFKAWAKPIKPFQITEGVWYVGTKNLSSILLTTPAGHILIDAGL
DESAPQIKANIEAAGFRLTDVRYLLNSHARLDQAGGMARLKAWSGAQLVASQPNADQMARGGRQDFALGDALPFPPVTTD
KIIHHQESIILGGITVTALFTPGHLPGSTSWRVTLRNGKTLIYADSLATPDYLLINNKNYPDLVTDIQSSFKTLAAQHVD
IFIANKGDRFGLLEKRQQLRNGDTQAFFDSNGLQQYVERSRQRFITQLTAQQP

Sequences:

>Translated_293_residues
MNRYALFLVCIFSTSALPAMAALDPSQPLSPAPPLSLFKAWAKPIKPFQITEGVWYVGTKNLSSILLTTPAGHILIDAGL
DESAPQIKANIEAAGFRLTDVRYLLNSHARLDQAGGMARLKAWSGAQLVASQPNADQMARGGRQDFALGDALPFPPVTTD
KIIHHQESIILGGITVTALFTPGHLPGSTSWRVTLRNGKTLIYADSLATPDYLLINNKNYPDLVTDIQSSFKTLAAQHVD
IFIANKGDRFGLLEKRQQLRNGDTQAFFDSNGLQQYVERSRQRFITQLTAQQP
>Mature_293_residues
MNRYALFLVCIFSTSALPAMAALDPSQPLSPAPPLSLFKAWAKPIKPFQITEGVWYVGTKNLSSILLTTPAGHILIDAGL
DESAPQIKANIEAAGFRLTDVRYLLNSHARLDQAGGMARLKAWSGAQLVASQPNADQMARGGRQDFALGDALPFPPVTTD
KIIHHQESIILGGITVTALFTPGHLPGSTSWRVTLRNGKTLIYADSLATPDYLLINNKNYPDLVTDIQSSFKTLAAQHVD
IFIANKGDRFGLLEKRQQLRNGDTQAFFDSNGLQQYVERSRQRFITQLTAQQP

Specific function: Has a high activity against imipenem [H]

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001018
- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 32099; Mature: 32099

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRYALFLVCIFSTSALPAMAALDPSQPLSPAPPLSLFKAWAKPIKPFQITEGVWYVGTK
CCCEEEEEEEECCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCEEEEECC
NLSSILLTTPAGHILIDAGLDESAPQIKANIEAAGFRLTDVRYLLNSHARLDQAGGMARL
CCCEEEEECCCCEEEEECCCCCCCCCEEEEEEECCEEHHHHHHHHHCCCHHHHCCCEEEE
KAWSGAQLVASQPNADQMARGGRQDFALGDALPFPPVTTDKIIHHQESIILGGITVTALF
EECCCCEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEECCEEEEEEE
TPGHLPGSTSWRVTLRNGKTLIYADSLATPDYLLINNKNYPDLVTDIQSSFKTLAAQHVD
CCCCCCCCCEEEEEEECCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEE
IFIANKGDRFGLLEKRQQLRNGDTQAFFDSNGLQQYVERSRQRFITQLTAQQP
EEEECCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNRYALFLVCIFSTSALPAMAALDPSQPLSPAPPLSLFKAWAKPIKPFQITEGVWYVGTK
CCCEEEEEEEECCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCEEEEECC
NLSSILLTTPAGHILIDAGLDESAPQIKANIEAAGFRLTDVRYLLNSHARLDQAGGMARL
CCCEEEEECCCCEEEEECCCCCCCCCEEEEEEECCEEHHHHHHHHHCCCHHHHCCCEEEE
KAWSGAQLVASQPNADQMARGGRQDFALGDALPFPPVTTDKIIHHQESIILGGITVTALF
EECCCCEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEECCEEEEEEE
TPGHLPGSTSWRVTLRNGKTLIYADSLATPDYLLINNKNYPDLVTDIQSSFKTLAAQHVD
CCCCCCCCCEEEEEEECCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEE
IFIANKGDRFGLLEKRQQLRNGDTQAFFDSNGLQQYVERSRQRFITQLTAQQP
EEEECCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8018721; 3931629; 9811546 [H]