Click here to switch to the map view.

The map label for this gene is celR [H]

Identifier: 16766920

GI number: 16766920

Start: 3819242

End: 3820249

Strand: Direct

Name: celR [H]

Synonym: STM3633

Alternate gene names: 16766920

Gene position: 3819242-3820249 (Clockwise)

Preceding gene: 16766912

Following gene: 16766928

Centisome position: 78.63

GC content: 60.32

Gene sequence:

>1008_bases
ATGGCTGTTCAAAATAAAAAACGCGCAAAGTTGATTGATGTTGCCCGCCATGCAGGCGTGTCGCCAGGGACAGTATCCAA
TGCATTGCACAACACTCGCTTTGTCGAGCCGCAGACGCGACGGCGTATTGAAGAGGCCATTGCTGCGCTCAACTACACGC
CGAATATTCGCGCTCGCCAGTTACGAACCGGCAAAACCAATACCATTGCTTTGCTCTCTTCGGTGCCGCTGGCGATTGCC
TCCGGCGCATCACGACTGGGATTTATGATGGAGGTGGCGTTAACGTCCGCGATGATGGCGCTGGAAAAGCAGCATGCGCT
GATTCTGGTGCCGCCGGGGGCAAATCCACTGGATGCCGTCAGCTTTGACGCGGCGATCCTGATTGAGCCGGCGGAGAACG
ACCCGCAGCTCCAGGCGCTGGCGCAAGCGGGCATTCCCTGCGTCACCATTGGCCGCACGCCGGGGACCGACACGCCTGTG
CCGTGGGTTGAGCTGCACTCGGCGGCAACAGCACAGCTTCTGCTAACGCATCTGGAGACCTCCGGCGCCAGCAAATGTGC
GTTATTTGTCGGTAACACTCGGCGAACATCAGTTCTGGAGAGCGAAGCGGCTTACCAGCGCTGGTGCGCGGGGCGCCAGG
CCCCCGTCGTCTACTCTCTCAATGAAAGCGAGGGTGAAAATGCCGGCTACCAGGCCGCGCAGCAGCTATTACAGGCGCAT
CCCGACGTTGACGGCGTGCTGGTGCTGATCGATACCTTTGCCAGCGGCGCGGTACGCGCTTTCCAGGAACAGGCAGTCGC
TATCCCGGAGCGGATGCGCGTGGTCACCCGCTATGATGGTATCCGCGCGCGCGAATCGCTGCCGCCGCTGACGGCTGTGA
ACATGCATCTTGATGAGGTGGCGCGACAGGCAATCACGCTCCTGTTTGCCGTTTTGTCGGGTGAGAAGATCAGCTACAGC
GACGGGATCATGCCTGAACTGGTGGTGAGAGCGTCAACCTGCCGGTGA

Upstream 100 bases:

>100_bases
TTAATGAAGGGTTTTTTACGATCCTCACTGAAAAAAAGCAAACGTTACCGTCTGGTAAATATGCTACCCTGTGCGCAAAT
TTTCGCAGGTCAGGAAGCAG

Downstream 100 bases:

>100_bases
TAGAGGATGACTCGCCACTACGTGGCTCGCCCTGCGGGCCGTTGCTGACGCAACGTTCTCTCGCTTCGCTCGAGTCGAAC
CTCTTGCCCCCGGAGGTTCT

Product: regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAVQNKKRAKLIDVARHAGVSPGTVSNALHNTRFVEPQTRRRIEEAIAALNYTPNIRARQLRTGKTNTIALLSSVPLAIA
SGASRLGFMMEVALTSAMMALEKQHALILVPPGANPLDAVSFDAAILIEPAENDPQLQALAQAGIPCVTIGRTPGTDTPV
PWVELHSAATAQLLLTHLETSGASKCALFVGNTRRTSVLESEAAYQRWCAGRQAPVVYSLNESEGENAGYQAAQQLLQAH
PDVDGVLVLIDTFASGAVRAFQEQAVAIPERMRVVTRYDGIRARESLPPLTAVNMHLDEVARQAITLLFAVLSGEKISYS
DGIMPELVVRASTCR

Sequences:

>Translated_335_residues
MAVQNKKRAKLIDVARHAGVSPGTVSNALHNTRFVEPQTRRRIEEAIAALNYTPNIRARQLRTGKTNTIALLSSVPLAIA
SGASRLGFMMEVALTSAMMALEKQHALILVPPGANPLDAVSFDAAILIEPAENDPQLQALAQAGIPCVTIGRTPGTDTPV
PWVELHSAATAQLLLTHLETSGASKCALFVGNTRRTSVLESEAAYQRWCAGRQAPVVYSLNESEGENAGYQAAQQLLQAH
PDVDGVLVLIDTFASGAVRAFQEQAVAIPERMRVVTRYDGIRARESLPPLTAVNMHLDEVARQAITLLFAVLSGEKISYS
DGIMPELVVRASTCR
>Mature_334_residues
AVQNKKRAKLIDVARHAGVSPGTVSNALHNTRFVEPQTRRRIEEAIAALNYTPNIRARQLRTGKTNTIALLSSVPLAIAS
GASRLGFMMEVALTSAMMALEKQHALILVPPGANPLDAVSFDAAILIEPAENDPQLQALAQAGIPCVTIGRTPGTDTPVP
WVELHSAATAQLLLTHLETSGASKCALFVGNTRRTSVLESEAAYQRWCAGRQAPVVYSLNESEGENAGYQAAQQLLQAHP
DVDGVLVLIDTFASGAVRAFQEQAVAIPERMRVVTRYDGIRARESLPPLTAVNMHLDEVARQAITLLFAVLSGEKISYSD
GIMPELVVRASTCR

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=317, Percent_Identity=27.7602523659306, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786540, Length=341, Percent_Identity=25.2199413489736, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790369, Length=350, Percent_Identity=23.1428571428571, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787580, Length=317, Percent_Identity=23.0283911671924, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790715, Length=316, Percent_Identity=23.4177215189873, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35989; Mature: 35858

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVQNKKRAKLIDVARHAGVSPGTVSNALHNTRFVEPQTRRRIEEAIAALNYTPNIRARQ
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHH
LRTGKTNTIALLSSVPLAIASGASRLGFMMEVALTSAMMALEKQHALILVPPGANPLDAV
CCCCCCCEEEEHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCC
SFDAAILIEPAENDPQLQALAQAGIPCVTIGRTPGTDTPVPWVELHSAATAQLLLTHLET
CCCEEEEEECCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
SGASKCALFVGNTRRTSVLESEAAYQRWCAGRQAPVVYSLNESEGENAGYQAAQQLLQAH
CCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHC
PDVDGVLVLIDTFASGAVRAFQEQAVAIPERMRVVTRYDGIRARESLPPLTAVNMHLDEV
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEHHHHHHHH
ARQAITLLFAVLSGEKISYSDGIMPELVVRASTCR
HHHHHHHHHHHHCCCEECCCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
AVQNKKRAKLIDVARHAGVSPGTVSNALHNTRFVEPQTRRRIEEAIAALNYTPNIRARQ
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHH
LRTGKTNTIALLSSVPLAIASGASRLGFMMEVALTSAMMALEKQHALILVPPGANPLDAV
CCCCCCCEEEEHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCC
SFDAAILIEPAENDPQLQALAQAGIPCVTIGRTPGTDTPVPWVELHSAATAQLLLTHLET
CCCEEEEEECCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
SGASKCALFVGNTRRTSVLESEAAYQRWCAGRQAPVVYSLNESEGENAGYQAAQQLLQAH
CCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHC
PDVDGVLVLIDTFASGAVRAFQEQAVAIPERMRVVTRYDGIRARESLPPLTAVNMHLDEV
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEHHHHHHHH
ARQAITLLFAVLSGEKISYSDGIMPELVVRASTCR
HHHHHHHHHHHHCCCEECCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]