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The map label for this gene is yhiP

Identifier: 16766878

GI number: 16766878

Start: 3761614

End: 3763083

Strand: Direct

Name: yhiP

Synonym: STM3592

Alternate gene names: 16766878

Gene position: 3761614-3763083 (Clockwise)

Preceding gene: 16766877

Following gene: 16766882

Centisome position: 77.44

GC content: 51.16

Gene sequence:

>1470_bases
ATGAATACAACTGCACCTACGGGCTTGCTGCAGCAACCTCGTCCATTCTTCATGATCTTTTTTGTAGAATTATGGGAACG
ATTTGGCTATTACGGCGTCCAGGGCATCCTGGCGGTCTTTTTCGTTAAACAATTGGGTTTTTCTCAGGAACAGGCCTTTA
TTACCTTTGGCGCTTTTGCAGCACTGGTTTATGGCCTGATCTCCATCGGCGGCTATGTTGGCGACCATCTGTTAGGGACT
AAACGCACCCTGGTCCTGGGCGCAATTGTGCTGGCGATTGGCTATTTTATGACCGGCATGTCGCTATTAAATCCCGATCT
GATTTTTATCGCACTGGGTACGATTGCCGTGGGCAACGGGTTATTTAAAGCCAATCCCGCCAGCCTGCTCTCTAAATGCT
ATCAGCCTAAAGATCCCCGGCTGGATGGCGCTTTCACCCTGTTTTATATGTCGATTAACATCGGTTCTTTGTTATCGCTA
TCGCTGGCGCCGGTGATTGCCGATAAATTTGGCTATGCGGTGACCTATAATCTGTGCGGCGCTGGTTTAATTGTTGCGCT
TCTGGTGTACTTCGCCTGCCGTGGCATGGTGAAAAATATCGGTTCTGAACCGGATCATAAACCGCTACGTTTTCGCAATT
TGCTGCTGGTACTACTCGGCACCGTCGTCATGATTTTCCTCTGCGCCTGGCTGATGCACAACGTTAAGATTGCCAATCTG
GTGCTCATCGTCCTTTCTATCGTCGTCACTATTTTCTTCTTTCGCGAAGCGTTTCGTCTGGATAAAACCGGCCGCAATAA
AATGTTCGTGGCGTTTATTCTGATGATTGAAGCCGTGCTGTTTTACATTCTGTATGCGCAGATGCCTACCTCGCTGAACT
TCTTTGCGATTAATAACGTGCATCATGAAATTCTTGGATTCGCCATTAACCCGGTGAGTTTTCAGGCGCTGAACCCATTC
TGGGTGGTCGTCGCCAGTCCGGTACTGGCAGCGATTTACACCCGGCTGGGTAGCAAAGGCAAAGATCTGACTATGCCGAT
GAAGTTTACGCTCGGCATGTTCCTCTGCGCGCTGGGTTTTCTGACCGCCGCCGCCGGGATGTGGTTTGCCGATGCGCAAG
GATTGACGTCGCCGTGGTTTATCGTGCTGGTGTATCTGTTCCAGAGTCTGGGCGAGTTGTTGATTAGCGCGCTGGGGCTG
GCAATGGTCGCCGCTCTGGTGCCGCAGCATCTGATGGGCTTTATTCTGGGAATGTGGTTCCTGACCCAGGCCGCCGCCTT
CCTGCTCGGCGGTTATGTGGCGACCTTCACTGCCGTACCGGAAAACATCACCGATCCGTTGCAGACGCTGCCCATTTATA
CCGGCGTCTTTAGCAAAATTGGTCTGGTAACGCTGGCGGTCACCGTGGTGATGGCCATTATGGTGCCGTGGTTAAACCGA
ATGATTAATACGCCAGGTACCGAACAGTAA

Upstream 100 bases:

>100_bases
ATCAGGCTAATAACCGCAGTCTATATCAGGGTAAGTCTTTTCGGCGCGTTTTGATATACGCGCTCATACGTTTCGGGATG
GCATTAAAAGGCGAAGGAAT

Downstream 100 bases:

>100_bases
TACTCAGTGCCGGATGCGGCTTACGCCTTATCCAGCCTACAAATAATTGAGAATCGTAGGCCCGATAAGCGTAGCTCCAT
CGGGCAATCCGTTACTCCGT

Product: inner membrane transporter YhiP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MNTTAPTGLLQQPRPFFMIFFVELWERFGYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGT
KRTLVLGAIVLAIGYFMTGMSLLNPDLIFIALGTIAVGNGLFKANPASLLSKCYQPKDPRLDGAFTLFYMSINIGSLLSL
SLAPVIADKFGYAVTYNLCGAGLIVALLVYFACRGMVKNIGSEPDHKPLRFRNLLLVLLGTVVMIFLCAWLMHNVKIANL
VLIVLSIVVTIFFFREAFRLDKTGRNKMFVAFILMIEAVLFYILYAQMPTSLNFFAINNVHHEILGFAINPVSFQALNPF
WVVVASPVLAAIYTRLGSKGKDLTMPMKFTLGMFLCALGFLTAAAGMWFADAQGLTSPWFIVLVYLFQSLGELLISALGL
AMVAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPENITDPLQTLPIYTGVFSKIGLVTLAVTVVMAIMVPWLNR
MINTPGTEQ

Sequences:

>Translated_489_residues
MNTTAPTGLLQQPRPFFMIFFVELWERFGYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGT
KRTLVLGAIVLAIGYFMTGMSLLNPDLIFIALGTIAVGNGLFKANPASLLSKCYQPKDPRLDGAFTLFYMSINIGSLLSL
SLAPVIADKFGYAVTYNLCGAGLIVALLVYFACRGMVKNIGSEPDHKPLRFRNLLLVLLGTVVMIFLCAWLMHNVKIANL
VLIVLSIVVTIFFFREAFRLDKTGRNKMFVAFILMIEAVLFYILYAQMPTSLNFFAINNVHHEILGFAINPVSFQALNPF
WVVVASPVLAAIYTRLGSKGKDLTMPMKFTLGMFLCALGFLTAAAGMWFADAQGLTSPWFIVLVYLFQSLGELLISALGL
AMVAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPENITDPLQTLPIYTGVFSKIGLVTLAVTVVMAIMVPWLNR
MINTPGTEQ
>Mature_489_residues
MNTTAPTGLLQQPRPFFMIFFVELWERFGYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGT
KRTLVLGAIVLAIGYFMTGMSLLNPDLIFIALGTIAVGNGLFKANPASLLSKCYQPKDPRLDGAFTLFYMSINIGSLLSL
SLAPVIADKFGYAVTYNLCGAGLIVALLVYFACRGMVKNIGSEPDHKPLRFRNLLLVLLGTVVMIFLCAWLMHNVKIANL
VLIVLSIVVTIFFFREAFRLDKTGRNKMFVAFILMIEAVLFYILYAQMPTSLNFFAINNVHHEILGFAINPVSFQALNPF
WVVVASPVLAAIYTRLGSKGKDLTMPMKFTLGMFLCALGFLTAAAGMWFADAQGLTSPWFIVLVYLFQSLGELLISALGL
AMVAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPENITDPLQTLPIYTGVFSKIGLVTLAVTVVMAIMVPWLNR
MINTPGTEQ

Specific function: Proton-dependent permease that transports di- and tripeptides

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily

Homologues:

Organism=Homo sapiens, GI4827008, Length=389, Percent_Identity=23.3933161953728, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI226371746, Length=358, Percent_Identity=24.8603351955307, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI226371748, Length=350, Percent_Identity=24.5714285714286, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1789911, Length=489, Percent_Identity=87.9345603271984, Blast_Score=883, Evalue=0.0,
Organism=Escherichia coli, GI1787922, Length=471, Percent_Identity=52.4416135881104, Blast_Score=519, Evalue=1e-148,
Organism=Escherichia coli, GI1786927, Length=437, Percent_Identity=26.3157894736842, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1790572, Length=480, Percent_Identity=27.7083333333333, Blast_Score=164, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17541704, Length=391, Percent_Identity=24.0409207161125, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17569141, Length=202, Percent_Identity=27.7227722772277, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28571098, Length=212, Percent_Identity=25.4716981132075, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571102, Length=212, Percent_Identity=25.4716981132075, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28571100, Length=212, Percent_Identity=25.4716981132075, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24639583, Length=342, Percent_Identity=24.2690058479532, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639585, Length=331, Percent_Identity=24.4712990936556, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639581, Length=331, Percent_Identity=24.4712990936556, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTPB_SALTY (Q8ZLD6)

Other databases:

- EMBL:   AE006468
- RefSeq:   NP_462493.1
- ProteinModelPortal:   Q8ZLD6
- GeneID:   1255115
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM3592
- NMPDR:   fig|99287.1.peg.3469
- HOGENOM:   HBG586603
- OMA:   RMINTPD
- ProtClustDB:   PRK10207
- BioCyc:   STYP99287:STM3592-MONOMER
- HAMAP:   MF_01879
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456
- PANTHER:   PTHR11654:SF6
- TIGRFAMs:   TIGR00924

Pfam domain/function: PF00854 PTR2; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 53600; Mature: 53600

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS01022 PTR2_1; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x124c6a04)-; HASH(0x124a8fc4)-; HASH(0x1017eb8c)-; HASH(0x126cabec)-; HASH(0x124fae58)-; HASH(0x11f4387c)-; HASH(0xd3e7d50)-; HASH(0x11b4ae18)-; HASH(0x12426f18)-; HASH(0x12458c38)-; HASH(0xd2d0adc)-; HASH(0x125fbfb0)-; HASH(0x124da6f8)-; HASH(0x1284cb58)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCH
>Mature Secondary Structure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HHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609