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The map label for this gene is tcp

Identifier: 16766863

GI number: 16766863

Start: 3744842

End: 3746485

Strand: Direct

Name: tcp

Synonym: STM3577

Alternate gene names: 16766863

Gene position: 3744842-3746485 (Clockwise)

Preceding gene: 16766862

Following gene: 16766865

Centisome position: 77.1

GC content: 55.66

Gene sequence:

>1644_bases
ATGAAAAATATCAAAGTCATCACCGGCGTTATCGCGACGCTGGGCATATTTAGCGCCTTATTGCTGGTGACAGGAATACT
GTTTTATTCCGCCGTCAGCAGCGATCGGCTGAATTTCCAGAATGCGAGCGCACTGAGTTACCAACAACAGGAACTGGGCG
GCAGTTTTCAGACATTGATCGAAACCCGCGTCACCATTAACCGCGTGGCGATACGCATGTTAAAAAATCAGCGCGATCCC
GCCTCACTGGACGCCATGAACACGCTGTTAACCAACGCTGGCGCGTCGCTCAACGAAGCGGAAAAACATTTCAACAACTA
CGTGAACTCCGAAGCGATCGCGGGCAAAGATCCGGCGTTGGATGCCCAGGCCGAAGCCAGCTTTAAGCAGATGTATGACG
TTTTGCAGCAGTCTATCCACTATCTTAAAGCCGATAATTACGCCGCCTATGGCAACCTTGACGCGCAAAAAGCGCAGGAT
GACATGGAGCAGGTATATGACCAGTGGCTCTCTCAAAATGCGCAATTAATAAAATTAGCCAGCGATCAGAATCAGAGCAG
CTTTACCCAGATGCAATGGACGCTGGGGATAATTCTACTTATCGTACTCATCGTGCTGGCGTTTATCTGGCTGGGGCTGC
AACGCGTTCTACTCCGCCCGCTGCAACGGATTATGGCGCACATTCAAACGATCGCCGACGGCGATCTTACCCATGAGATA
GAGGCTGAAGGACGCAGTGAAATGGGCCAACTGGCCGCCGGTCTCAAAACGATGCAGCAGTCGTTAATCCGTACCGTCAG
CGCGGTGCGCGATAACGCAGACTCTATCTATACTGGCGCAGGCGAAATTTCCGCCGGCAGCAGCGACCTCTCTTCCCGTA
CCGAACAGCAGGCCTCGGCGCTGGAGGAGACCGCCGCCAGCATGGAACAGTTAACCGCCACGGTACGGCAAAACACCGAT
AACGCACGACAGGCGACGGGTCTGGCGAAAACCGCATCAGAAACCGCGCGTAAAGGAGGACGCGTGGTGGATAACGTAGT
GAGCACCATGAACGATATCGCCGAAAGCTCGGAAAAAATTGTGGACATCACCAGCGTGATTGACGGTATCGCCTTCCAGA
CTAATATCCTGGCGCTGAACGCCGCGGTAGAAGCCGCCCGCGCCGGCGAACAGGGGCGAGGATTCGCGGTCGTGGCCGGA
GAGGTACGCACGTTGGCCAGCCGTAGCGCGCAGGCCGCCAAAGAGATCAAAGTACTGATTGAAAACTCCGTGTCGCGCAT
TGATACCGGCTCTACGCAGGTACGCGAAGCGGGAGAAACCATGAAAGAGATCGTCAACGCCGTGACCCGCGTGACCGATA
TTATGGGCGAAATCGCCTCTGCCTCCGATGAGCAAAGCAAAGGCATTGAGCAGGTGGCGCAGGCGGTATCGGAAATGGAC
AGCGTGACGCAGCAAAACGCCTCGCTGGTAGAAGAATCCGCAGCAGCGGCGGCGGCGCTGGAAGATCAGGCTAACGAACT
TCGTCAGGCGGTCGCCGCGTTCCGCATCCAGAAACAGCCTCGTCGGGAGGCGTCGCCAACGACGTTAAGCAAAGGTTTAA
CGCCACAGCCCGCCGCAGAACAGGCGAACTGGGAAAGCTTCTAA

Upstream 100 bases:

>100_bases
ATCAAACCATTAATCAGAAATAGCGTGATTTGATGTAAGGTTAATTTTTATCCAACCGATATTGATCATACCGTCTACAA
AATAAGGAATGTTAGGCACT

Downstream 100 bases:

>100_bases
TCAGAATAGTATCTGCCGTGCAGTTAATGCGCTTTACGCAATAAATAACGGTACGGCAGACCCTCCGTCTCTTGCGCCAG
CAAATCGTGTTCCATAAAGG

Product: methyl-accepting transmembrane citrate/phenol chemoreceptor

Products: NA

Alternate protein names: Citrate chemoreceptor protein

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLIETRVTINRVAIRMLKNQRDP
ASLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPALDAQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQD
DMEQVYDQWLSQNAQLIKLASDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEI
EAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASALEETAASMEQLTATVRQNTD
NARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKIVDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLASRSAQAAKEIKVLIENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMD
SVTQQNASLVEESAAAAAALEDQANELRQAVAAFRIQKQPRREASPTTLSKGLTPQPAAEQANWESF

Sequences:

>Translated_547_residues
MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLIETRVTINRVAIRMLKNQRDP
ASLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPALDAQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQD
DMEQVYDQWLSQNAQLIKLASDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEI
EAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASALEETAASMEQLTATVRQNTD
NARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKIVDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLASRSAQAAKEIKVLIENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMD
SVTQQNASLVEESAAAAAALEDQANELRQAVAAFRIQKQPRREASPTTLSKGLTPQPAAEQANWESF
>Mature_547_residues
MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLIETRVTINRVAIRMLKNQRDP
ASLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPALDAQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQD
DMEQVYDQWLSQNAQLIKLASDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEI
EAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASALEETAASMEQLTATVRQNTD
NARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKIVDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLASRSAQAAKEIKVLIENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMD
SVTQQNASLVEESAAAAAALEDQANELRQAVAAFRIQKQPRREASPTTLSKGLTPQPAAEQANWESF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain

Homologues:

Organism=Escherichia coli, GI2367378, Length=554, Percent_Identity=53.4296028880866, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1788195, Length=555, Percent_Identity=53.3333333333333, Blast_Score=494, Evalue=1e-141,
Organism=Escherichia coli, GI1787690, Length=460, Percent_Identity=48.9130434782609, Blast_Score=383, Evalue=1e-107,
Organism=Escherichia coli, GI1788194, Length=445, Percent_Identity=50.1123595505618, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1789453, Length=329, Percent_Identity=41.9452887537994, Blast_Score=221, Evalue=8e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MCPC_SALTY (Q02755)

Other databases:

- EMBL:   L06029
- EMBL:   AE006468
- PIR:   A47178
- RefSeq:   NP_462478.1
- ProteinModelPortal:   Q02755
- PRIDE:   Q02755
- GeneID:   1255100
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM3577
- NMPDR:   fig|99287.1.peg.3454
- HOGENOM:   HBG752668
- OMA:   NTMNDIA
- ProtClustDB:   CLSK894525
- BioCyc:   STYP99287:STM3577-MONOMER
- GO:   GO:0006935
- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660
- Gene3D:   G3DSA:1.20.120.30
- PRINTS:   PR00260
- SMART:   SM00304
- SMART:   SM00283
- SMART:   SM00319

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH; SSF47170 Chemotax_Me-accpt_rcpt_lig-bd

EC number: NA

Molecular weight: Translated: 58951; Mature: 58951

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00538 CHEMOTAXIS_TRANSDUC_1; PS50111 CHEMOTAXIS_TRANSDUC_2; PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x116411f8)-; HASH(0x118e37a8)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHH
ETRVTINRVAIRMLKNQRDPASLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPAL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
DAQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQDDMEQVYDQWLSQNAQLIKLA
CCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEC
SDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHH
LEETAASMEQLTATVRQNTDNARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLASRSAQAAKEIKVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
ENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMD
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SVTQQNASLVEESAAAAAALEDQANELRQAVAAFRIQKQPRREASPTTLSKGLTPQPAAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCC
QANWESF
CCCCCCH
>Mature Secondary Structure
MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHH
ETRVTINRVAIRMLKNQRDPASLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPAL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
DAQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQDDMEQVYDQWLSQNAQLIKLA
CCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEC
SDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHH
LEETAASMEQLTATVRQNTDNARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLASRSAQAAKEIKVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
ENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMD
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SVTQQNASLVEESAAAAAALEDQANELRQAVAAFRIQKQPRREASPTTLSKGLTPQPAAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCC
QANWESF
CCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609