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The map label for this gene is hopD

Identifier: 16766731

GI number: 16766731

Start: 3596910

End: 3597377

Strand: Direct

Name: hopD

Synonym: STM3442

Alternate gene names: 16766731

Gene position: 3596910-3597377 (Clockwise)

Preceding gene: 16766699

Following gene: 16766743

Centisome position: 74.05

GC content: 52.99

Gene sequence:

>468_bases
ATGTTTGTTGCCCTCCCCTTTCTCATTTTTTATGCGTCGTTCTCTTTATTACTTGGCATATACGACGCGCGTACCGGTCT
GCTGCCTGACCGGTTTACTTGTCCATTGCTGTGGGGTGGTCTGCTTTATCACCAGATTTGCCTGCCGGAGCGTTTACCGG
ATGCGCTTTGGGGCGCTATCGCCGGCTATGGCGGATTCGCGTTAATTTACTGGGGCTATCGCCTGCGTTATCAGAAAGAG
GGGCTTGGATATGGCGACGTCAAGTACCTCGCTGCCTTAGGGGCGTGGCATTGTTGGGAAACACTGCCGTTACTGGTTTT
CCTTGCCGCTATGTTGGCCTGTGGCGGGTTTGGCGTCGCGCTACTGGTGAGAGGTAAATCGGCATTAATAAACCCGCTAC
CTTTTGGGCCATGGCTGGCGGTGGCGGGTTTCATAACAGGTTGGAAAGTTTTCTTTCCAGACGGTTAA

Upstream 100 bases:

>100_bases
ATCTTTTCTTTGGAAGGCATCAGGCAAACCTGGCAATACGTCGTTGTCGCTGTCGCATAAATCTATAAAGGTGAGCGCAA
GCCTTGACGAGGATTTGCTT

Downstream 100 bases:

>100_bases
TCGGTAACCTTAATTTGTGATTGCAGATAATTTTGCATACCAAGTTTGGCAATCAAATCCAACTCAGTTTCCAGCCAGTC
GATGTGGCCTTCCTCGTCGG

Product: leader peptidase HopD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MFVALPFLIFYASFSLLLGIYDARTGLLPDRFTCPLLWGGLLYHQICLPERLPDALWGAIAGYGGFALIYWGYRLRYQKE
GLGYGDVKYLAALGAWHCWETLPLLVFLAAMLACGGFGVALLVRGKSALINPLPFGPWLAVAGFITGWKVFFPDG

Sequences:

>Translated_155_residues
MFVALPFLIFYASFSLLLGIYDARTGLLPDRFTCPLLWGGLLYHQICLPERLPDALWGAIAGYGGFALIYWGYRLRYQKE
GLGYGDVKYLAALGAWHCWETLPLLVFLAAMLACGGFGVALLVRGKSALINPLPFGPWLAVAGFITGWKVFFPDG
>Mature_155_residues
MFVALPFLIFYASFSLLLGIYDARTGLLPDRFTCPLLWGGLLYHQICLPERLPDALWGAIAGYGGFALIYWGYRLRYQKE
GLGYGDVKYLAALGAWHCWETLPLLVFLAAMLACGGFGVALLVRGKSALINPLPFGPWLAVAGFITGWKVFFPDG

Specific function: Cleaves Type-4 Fimbrial Leader Sequence And Methylates The N-Terminal (Generally Phe) Residue (By Similarity). [C]

COG id: COG1989

COG function: function code NOU; Type II secretory pathway, prepilin signal peptidase PulO and related peptidases

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A24 family

Homologues:

Organism=Escherichia coli, GI1789732, Length=140, Percent_Identity=45.7142857142857, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HOPD_SALTY (O68927)

Other databases:

- EMBL:   AF058449
- EMBL:   AE006468
- RefSeq:   NP_462346.1
- MEROPS:   A24.003
- GeneID:   1254965
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM3442
- HOGENOM:   HBG754332
- OMA:   CNPDGLA
- ProtClustDB:   CLSK880637
- BioCyc:   STYP99287:STM3442-MONOMER
- GO:   GO:0016020
- InterPro:   IPR014032
- InterPro:   IPR000045
- PRINTS:   PR00864

Pfam domain/function: PF01478 Peptidase_A24

EC number: 3.4.23.43

Molecular weight: Translated: 17099; Mature: 17099

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVALPFLIFYASFSLLLGIYDARTGLLPDRFTCPLLWGGLLYHQICLPERLPDALWGAI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AGYGGFALIYWGYRLRYQKEGLGYGDVKYLAALGAWHCWETLPLLVFLAAMLACGGFGVA
HCCCCCEEEEHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LLVRGKSALINPLPFGPWLAVAGFITGWKVFFPDG
EEEECCHHHCCCCCCCHHHHHHHHHHCCEEEECCC
>Mature Secondary Structure
MFVALPFLIFYASFSLLLGIYDARTGLLPDRFTCPLLWGGLLYHQICLPERLPDALWGAI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AGYGGFALIYWGYRLRYQKEGLGYGDVKYLAALGAWHCWETLPLLVFLAAMLACGGFGVA
HCCCCCEEEEHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LLVRGKSALINPLPFGPWLAVAGFITGWKVFFPDG
EEEECCHHHCCCCCCCHHHHHHHHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677609