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The map label for this gene is oadA [H]

Identifier: 16766647

GI number: 16766647

Start: 3520046

End: 3521821

Strand: Reverse

Name: oadA [H]

Synonym: STM3352

Alternate gene names: 16766647

Gene position: 3521821-3520046 (Counterclockwise)

Preceding gene: 16766648

Following gene: 16766646

Centisome position: 72.5

GC content: 63.63

Gene sequence:

>1776_bases
ATGACCATTGCCATTACCGATGTCGTCCTGCGTGACGCTCACCAGTCTCTGTTCGCCACCCGCCTGCGCCTTGATGACAT
GCTGCCGATTGCCGCCGCGCTCGATGACGTGGGCTACGGGTCGCTGGAGTGCTGGGGCGGCGCCACCTTTGACGCCTGTA
TCCGCTTTCTCGGCGAAGACCCGTGGCTGCGCCTGCGCGAACTCAAAAAAGCCATGCCCAAAACCCCGCTGCAGATGTTG
CTGCGCGGCCAGAACCTGCTCGGCTACCGCCACTACGCCGATGACGTGGTGGAGCGCTTCGTCGAACGCGCGGTGAAAAA
CGGCATGGATGTGTTCCGCGTCTTCGATGCCATGAACGACCCGCGCAATATGAAAGCCGCATTACAGGCGGTGCGCAGCC
ACGGCGCGCACGCCCAGGGGACCCTGAGTTACACCACCAGCCCGGCGCACACCCTGCAGACCTGGCTGGATTTAACGGAG
CAACTGCTGGAAACCGGCGTTGACTCGATTGCCATCAAGGATATGTCCGGCATTCTCACACCGATGGCGGCGTATGAGCT
GGTCAGCGAAATCAAAAAACGTTTTGAGGTGCGCCTGCACCTGCACTGTCACGCCACCACCGGGATGGCGGAGATGGCCC
TGCTGAAGGCTATCGAGGCGGGCGTCGACGGCGTGGACACGGCGATTTCCTCCATGAGCGCCACCTACGGCCACCCGGCC
ACCGAAGCGCTGGTGGCAACGCTTGCCGGCACGGAACACGACACCGGGCTGGATATCCTGAAGCTGGAAAATATCGCCGC
GTACTTCCGCGAGGTGCGCAAAAAGTATCACGCCTTTGAAGGCCAGCTGAAGGGCTACGACAGCCGTATTCTGGTGGCCC
AGGTACCGGGCGGAATGCTCACCAACCTCGAAAGCCAGCTGAAGCAGCAGAACGCGGCGGACAAACTCGACCAGGTGCTG
GCGGAAATCCCCCGCGTGCGCGAGGACCTCGGCTTTATCCCGCTGGTGACCCCAACCTCGCAGATTGTCGGCACCCAGGC
GGTGCTCAACGTCCTGACCGGCGAGCGCTACAAAACCATTGCCAAAGAAACGGCGGGCATTCTGAAAGGCGAATACGGCC
ACACCCCGGTGCCGGTGAACGCCGCGTTACAGGCCCGCGTGCTGGAAGGGGGCGCCCCGGTGACCTGCCGTCCGGCGGAT
TTACTCAAACCGGAGCTGGCTGAACTGGAAGCGGACGTCAGGCGCCAGGCGCAGGAGAAGGGGATTACTCTGGCGGGAAA
CGCCATCGACGACGTGCTCACCGTGGCGCTGTTCCCGCAAATCGGCCTCAAATTCCTTGAGAACCGCAATAACCCGGCGG
CGTTTGAGCCACTGCCGCAGGCGGAAGCCGCGCAGCCGGTGGCAAAAGCAGAGAAGCCTGCCGCCTCCGGTATCTACACC
GTGGAAGTGGAAGGCAAAGCCTTTGTGGTGAAGGTCAGCGACGGCGGCGATATCAGCCAGCTCACTGCGGCTGTTCCGGC
GGCCTCTTCCGCACCGGTTCAGGCTGCCGCCCCGGCAGGCGCCGGCACCCCGGTCACCGCGCCGCTGGCGGGGAATATCT
GGAAGGTGATTGCCACCGAGGGCCAGACGGTGGCCGAAGGCGACGTGCTGCTGATTCTGGAAGCCATGAAGATGGAAACC
GAAATCCGCGCCGCGCAGGCCGGGACGGTACGCGGTATCGCGGTGAAGTCCGGGGACGCGGTCTCCGTCGGCGACACCCT
GATGACGCTGGCGTAA

Upstream 100 bases:

>100_bases
CGCCGCGCCCGTCGTGGACGACTTCACCCGCTTAAAGCCGGTCATTGCCGCCGCTATCCACCACCATCACCGCCTTAATG
CTTAATTCCCGGAGGGATCC

Downstream 100 bases:

>100_bases
CGGAGAACTGAAATGGAAAGTCTGAACGCCCTGCTTCAGGGCATGGGGCTGATGCACCTTGGCGCAGGCCAGGCCATCAT
GCTGCTGGTCAGCCTGCTGC

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 591; Mature: 590

Protein sequence:

>591_residues
MTIAITDVVLRDAHQSLFATRLRLDDMLPIAAALDDVGYGSLECWGGATFDACIRFLGEDPWLRLRELKKAMPKTPLQML
LRGQNLLGYRHYADDVVERFVERAVKNGMDVFRVFDAMNDPRNMKAALQAVRSHGAHAQGTLSYTTSPAHTLQTWLDLTE
QLLETGVDSIAIKDMSGILTPMAAYELVSEIKKRFEVRLHLHCHATTGMAEMALLKAIEAGVDGVDTAISSMSATYGHPA
TEALVATLAGTEHDTGLDILKLENIAAYFREVRKKYHAFEGQLKGYDSRILVAQVPGGMLTNLESQLKQQNAADKLDQVL
AEIPRVREDLGFIPLVTPTSQIVGTQAVLNVLTGERYKTIAKETAGILKGEYGHTPVPVNAALQARVLEGGAPVTCRPAD
LLKPELAELEADVRRQAQEKGITLAGNAIDDVLTVALFPQIGLKFLENRNNPAAFEPLPQAEAAQPVAKAEKPAASGIYT
VEVEGKAFVVKVSDGGDISQLTAAVPAASSAPVQAAAPAGAGTPVTAPLAGNIWKVIATEGQTVAEGDVLLILEAMKMET
EIRAAQAGTVRGIAVKSGDAVSVGDTLMTLA

Sequences:

>Translated_591_residues
MTIAITDVVLRDAHQSLFATRLRLDDMLPIAAALDDVGYGSLECWGGATFDACIRFLGEDPWLRLRELKKAMPKTPLQML
LRGQNLLGYRHYADDVVERFVERAVKNGMDVFRVFDAMNDPRNMKAALQAVRSHGAHAQGTLSYTTSPAHTLQTWLDLTE
QLLETGVDSIAIKDMSGILTPMAAYELVSEIKKRFEVRLHLHCHATTGMAEMALLKAIEAGVDGVDTAISSMSATYGHPA
TEALVATLAGTEHDTGLDILKLENIAAYFREVRKKYHAFEGQLKGYDSRILVAQVPGGMLTNLESQLKQQNAADKLDQVL
AEIPRVREDLGFIPLVTPTSQIVGTQAVLNVLTGERYKTIAKETAGILKGEYGHTPVPVNAALQARVLEGGAPVTCRPAD
LLKPELAELEADVRRQAQEKGITLAGNAIDDVLTVALFPQIGLKFLENRNNPAAFEPLPQAEAAQPVAKAEKPAASGIYT
VEVEGKAFVVKVSDGGDISQLTAAVPAASSAPVQAAAPAGAGTPVTAPLAGNIWKVIATEGQTVAEGDVLLILEAMKMET
EIRAAQAGTVRGIAVKSGDAVSVGDTLMTLA
>Mature_590_residues
TIAITDVVLRDAHQSLFATRLRLDDMLPIAAALDDVGYGSLECWGGATFDACIRFLGEDPWLRLRELKKAMPKTPLQMLL
RGQNLLGYRHYADDVVERFVERAVKNGMDVFRVFDAMNDPRNMKAALQAVRSHGAHAQGTLSYTTSPAHTLQTWLDLTEQ
LLETGVDSIAIKDMSGILTPMAAYELVSEIKKRFEVRLHLHCHATTGMAEMALLKAIEAGVDGVDTAISSMSATYGHPAT
EALVATLAGTEHDTGLDILKLENIAAYFREVRKKYHAFEGQLKGYDSRILVAQVPGGMLTNLESQLKQQNAADKLDQVLA
EIPRVREDLGFIPLVTPTSQIVGTQAVLNVLTGERYKTIAKETAGILKGEYGHTPVPVNAALQARVLEGGAPVTCRPADL
LKPELAELEADVRRQAQEKGITLAGNAIDDVLTVALFPQIGLKFLENRNNPAAFEPLPQAEAAQPVAKAEKPAASGIYTV
EVEGKAFVVKVSDGGDISQLTAAVPAASSAPVQAAAPAGAGTPVTAPLAGNIWKVIATEGQTVAEGDVLLILEAMKMETE
IRAAQAGTVRGIAVKSGDAVSVGDTLMTLA

Specific function: Lyase and sodium transporter [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=630, Percent_Identity=33.6507936507937, Blast_Score=285, Evalue=1e-76,
Organism=Homo sapiens, GI106049295, Length=630, Percent_Identity=33.6507936507937, Blast_Score=285, Evalue=1e-76,
Organism=Homo sapiens, GI106049292, Length=630, Percent_Identity=33.6507936507937, Blast_Score=285, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17562816, Length=623, Percent_Identity=34.1894060995185, Blast_Score=312, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6319695, Length=629, Percent_Identity=32.7503974562798, Blast_Score=304, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6321376, Length=629, Percent_Identity=31.9554848966614, Blast_Score=294, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24652212, Length=635, Percent_Identity=31.6535433070866, Blast_Score=285, Evalue=5e-77,
Organism=Drosophila melanogaster, GI24652210, Length=635, Percent_Identity=31.6535433070866, Blast_Score=285, Evalue=5e-77,
Organism=Drosophila melanogaster, GI24652214, Length=635, Percent_Identity=31.6535433070866, Blast_Score=285, Evalue=5e-77,
Organism=Drosophila melanogaster, GI19921944, Length=635, Percent_Identity=31.6535433070866, Blast_Score=285, Evalue=5e-77,
Organism=Drosophila melanogaster, GI24652216, Length=635, Percent_Identity=31.6535433070866, Blast_Score=285, Evalue=5e-77,
Organism=Drosophila melanogaster, GI281363050, Length=635, Percent_Identity=31.6535433070866, Blast_Score=285, Evalue=6e-77,
Organism=Drosophila melanogaster, GI24652224, Length=635, Percent_Identity=31.6535433070866, Blast_Score=285, Evalue=6e-77,
Organism=Drosophila melanogaster, GI24652222, Length=635, Percent_Identity=31.6535433070866, Blast_Score=285, Evalue=6e-77,
Organism=Drosophila melanogaster, GI24652220, Length=635, Percent_Identity=31.6535433070866, Blast_Score=285, Evalue=6e-77,
Organism=Drosophila melanogaster, GI24652218, Length=635, Percent_Identity=31.6535433070866, Blast_Score=285, Evalue=6e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR005776
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =4.1.1.3 [H]

Molecular weight: Translated: 63207; Mature: 63076

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAITDVVLRDAHQSLFATRLRLDDMLPIAAALDDVGYGSLECWGGATFDACIRFLGED
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCC
PWLRLRELKKAMPKTPLQMLLRGQNLLGYRHYADDVVERFVERAVKNGMDVFRVFDAMND
CHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
PRNMKAALQAVRSHGAHAQGTLSYTTSPAHTLQTWLDLTEQLLETGVDSIAIKDMSGILT
CHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
PMAAYELVSEIKKRFEVRLHLHCHATTGMAEMALLKAIEAGVDGVDTAISSMSATYGHPA
HHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCH
TEALVATLAGTEHDTGLDILKLENIAAYFREVRKKYHAFEGQLKGYDSRILVAQVPGGML
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHH
TNLESQLKQQNAADKLDQVLAEIPRVREDLGFIPLVTPTSQIVGTQAVLNVLTGERYKTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCHHHHHH
AKETAGILKGEYGHTPVPVNAALQARVLEGGAPVTCRPADLLKPELAELEADVRRQAQEK
HHHHHHHHCCCCCCCCCCCCHHHHHHEECCCCCEEECCHHHCCHHHHHHHHHHHHHHHHC
GITLAGNAIDDVLTVALFPQIGLKFLENRNNPAAFEPLPQAEAAQPVAKAEKPAASGIYT
CCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHCCCCCCCCEEE
VEVEGKAFVVKVSDGGDISQLTAAVPAASSAPVQAAAPAGAGTPVTAPLAGNIWKVIATE
EEECCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEEEECC
GQTVAEGDVLLILEAMKMETEIRAAQAGTVRGIAVKSGDAVSVGDTLMTLA
CCEEECCCEEEEEHHHHHHHHHHHHHCCCEEEEEEECCCCEECCCHHHHCC
>Mature Secondary Structure 
TIAITDVVLRDAHQSLFATRLRLDDMLPIAAALDDVGYGSLECWGGATFDACIRFLGED
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCC
PWLRLRELKKAMPKTPLQMLLRGQNLLGYRHYADDVVERFVERAVKNGMDVFRVFDAMND
CHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
PRNMKAALQAVRSHGAHAQGTLSYTTSPAHTLQTWLDLTEQLLETGVDSIAIKDMSGILT
CHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
PMAAYELVSEIKKRFEVRLHLHCHATTGMAEMALLKAIEAGVDGVDTAISSMSATYGHPA
HHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCH
TEALVATLAGTEHDTGLDILKLENIAAYFREVRKKYHAFEGQLKGYDSRILVAQVPGGML
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHH
TNLESQLKQQNAADKLDQVLAEIPRVREDLGFIPLVTPTSQIVGTQAVLNVLTGERYKTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCHHHHHH
AKETAGILKGEYGHTPVPVNAALQARVLEGGAPVTCRPADLLKPELAELEADVRRQAQEK
HHHHHHHHCCCCCCCCCCCCHHHHHHEECCCCCEEECCHHHCCHHHHHHHHHHHHHHHHC
GITLAGNAIDDVLTVALFPQIGLKFLENRNNPAAFEPLPQAEAAQPVAKAEKPAASGIYT
CCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHCCCCCCCCEEE
VEVEGKAFVVKVSDGGDISQLTAAVPAASSAPVQAAAPAGAGTPVTAPLAGNIWKVIATE
EEECCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEEEECC
GQTVAEGDVLLILEAMKMETEIRAAQAGTVRGIAVKSGDAVSVGDTLMTLA
CCEEECCCEEEEEHHHHHHHHHHHHHCCCEEEEEEECCCCEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2454915 [H]