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The map label for this gene is ygiY [H]

Identifier: 16766478

GI number: 16766478

Start: 3341454

End: 3342803

Strand: Direct

Name: ygiY [H]

Synonym: STM3178

Alternate gene names: 16766478

Gene position: 3341454-3342803 (Clockwise)

Preceding gene: 16766477

Following gene: 16766479

Centisome position: 68.79

GC content: 56.3

Gene sequence:

>1350_bases
ATGAAATTGACGCAACGTCTCAGCCTGCGCGTCAGGCTGACGCTTATTTTCCTGATTCTGGTCTCCATCACCTGGGCAAT
CTCCAGTTTTGTGGCCTGGAGAAAGACGACGGATAATGTCGACGAGCTGTTTGACACACAGTTGATGTTGTTCGCCAGAC
GGCTTAGCACCCTCGATCTTAACGAGATCAACGCCCCGCAGCGCATGGCGCATACGCCAAAGAAATTAAAACATGGGCAT
ATCGATGACGATGCGCTGGCGTTCGCCATCTTTTCCGCTGACGGCAAAATGTTGCTGCATGATGGCGACAACGGCCAGGA
TATTCCGTATCGCTATCGCCGGGAAGGTTTCGACAATGGCTATCTGAAGGATGACAACGACCTCTGGCGTTTTTTGTGGT
TGAACTCGGCGGACGGCAAGTATCGTATCGTCGTCGGTCAGGAGTGGGATTACCGCGAAGATATGGCGCTGGCGATCGTG
GCGGCGCAATTAACGCCGTGGCTGATCGCCCTTCCCTTCATGCTGCTAATTTTATTACTCCTGCTTCACCGCGAGCTCAG
ACCATTGAAAAAACTGGCGCAGGCGCTACGCTTCCGGTCGCCGGAATCGGAAACGCCGCTCGACGCCAAAGGCGTACCGA
GCGAGGTTCGCCCACTGGTCGAAGCGCTTAATCAGCTTTTTAGCCGCATCCACTCCATGATGGTGCGCGAACGGCGATTT
ACCTCCGACGCCGCCCATGAATTGCGCAGCCCGCTGGCCGCGCTGAAAGTACAAACCGAGGTGGCGCAGCTCTCGGGCGA
CGATCCGCTATCGCGTGATAAAGCGCTGACCCAGCTCCATGCGGGGATCGATCGCGCCACGCGACTGGTCGATCAGCTAC
TGACGTTATCGCGTCTCGACTCGCTCAATAATTTGCAGGATGTAGCGGAGATTTCGCTGGAAGAGCTGCTGCAGTCCGCG
GTAATGGATATTTATCATCCGGCGCAGCAGGCGAATATCGACGTGCGTTTACAGCTTAACGCCCATGACGTCATACGTAC
CGGCCAGCCGCTACTCTTAAGCCTGTTAGTGCGTAACCTGCTGGATAATGCGATTCGCTACAGTCCGCAGGGCAGCGTCG
TCGACGTTACCTTACATGCCCGCAGCTTCACCGTCAGAGATAATGGCCCCGGCGTAGCGCCAGAGATTCTGACGCATATC
GGCGAGCGTTTTTACCGCCCGCCAGGCCAAAGTGTGACCGGCAGCGGTCTGGGATTATCAATCGTCCGCCGCATCGCTAC
GCTGCACGGCATGACGGTGTCGTTTGGCAACGCCGCGGAAGGTGGATTTGAGGCCGTAGTAAGTTGGTAA

Upstream 100 bases:

>100_bases
CCAGCAATGCAGTGGAAGTCCATGTTCATCATTTACGCCGCAAGCTCGGCAGCGAATTTATTCGCACCGTGCACGGCATC
GGCTACACCCTGGGTGACGC

Downstream 100 bases:

>100_bases
CAGAGACTTTTGCCAAAAACGCAAAAGACTTTGCACATTTTGCTAATTTCACCGCACCGCCCGTCAGCGTAGAATCAGCA
GCAAACGCATTTCTTGAGGA

Product: sensor protein QseC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELFDTQLMLFARRLSTLDLNEINAPQRMAHTPKKLKHGH
IDDDALAFAIFSADGKMLLHDGDNGQDIPYRYRREGFDNGYLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIV
AAQLTPWLIALPFMLLILLLLLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRPLVEALNQLFSRIHSMMVRERRF
TSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKALTQLHAGIDRATRLVDQLLTLSRLDSLNNLQDVAEISLEELLQSA
VMDIYHPAQQANIDVRLQLNAHDVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLHARSFTVRDNGPGVAPEILTHI
GERFYRPPGQSVTGSGLGLSIVRRIATLHGMTVSFGNAAEGGFEAVVSW

Sequences:

>Translated_449_residues
MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELFDTQLMLFARRLSTLDLNEINAPQRMAHTPKKLKHGH
IDDDALAFAIFSADGKMLLHDGDNGQDIPYRYRREGFDNGYLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIV
AAQLTPWLIALPFMLLILLLLLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRPLVEALNQLFSRIHSMMVRERRF
TSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKALTQLHAGIDRATRLVDQLLTLSRLDSLNNLQDVAEISLEELLQSA
VMDIYHPAQQANIDVRLQLNAHDVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLHARSFTVRDNGPGVAPEILTHI
GERFYRPPGQSVTGSGLGLSIVRRIATLHGMTVSFGNAAEGGFEAVVSW
>Mature_449_residues
MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELFDTQLMLFARRLSTLDLNEINAPQRMAHTPKKLKHGH
IDDDALAFAIFSADGKMLLHDGDNGQDIPYRYRREGFDNGYLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIV
AAQLTPWLIALPFMLLILLLLLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRPLVEALNQLFSRIHSMMVRERRF
TSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKALTQLHAGIDRATRLVDQLLTLSRLDSLNNLQDVAEISLEELLQSA
VMDIYHPAQQANIDVRLQLNAHDVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLHARSFTVRDNGPGVAPEILTHI
GERFYRPPGQSVTGSGLGLSIVRRIATLHGMTVSFGNAAEGGFEAVVSW

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=449, Percent_Identity=79.2873051224944, Blast_Score=713, Evalue=0.0,
Organism=Escherichia coli, GI1790551, Length=277, Percent_Identity=33.9350180505415, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1786783, Length=350, Percent_Identity=28.2857142857143, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788279, Length=283, Percent_Identity=28.2685512367491, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787894, Length=236, Percent_Identity=30.9322033898305, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786600, Length=214, Percent_Identity=29.9065420560748, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=31.6872427983539, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786912, Length=236, Percent_Identity=31.3559322033898, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790346, Length=242, Percent_Identity=29.7520661157025, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790861, Length=250, Percent_Identity=30.8, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789808, Length=295, Percent_Identity=27.4576271186441, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50539; Mature: 50539

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELFDTQLMLFARRLSTLDL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
NEINAPQRMAHTPKKLKHGHIDDDALAFAIFSADGKMLLHDGDNGQDIPYRYRREGFDNG
HHCCCCHHHHCCHHHHCCCCCCCHHHEEEEEECCCEEEEECCCCCCCCCHHHHHCCCCCC
YLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIVAAQLTPWLIALPFMLLILLL
CCCCCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRPLVEALNQLFSRIHSMMVRERRF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKALTQLHAGIDRATRLVDQLLTLSRLD
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLNNLQDVAEISLEELLQSAVMDIYHPAQQANIDVRLQLNAHDVIRTGQPLLLSLLVRNL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEEEECHHHHHHCCHHHHHHHHHHHH
LDNAIRYSPQGSVVDVTLHARSFTVRDNGPGVAPEILTHIGERFYRPPGQSVTGSGLGLS
HHHHHHCCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHH
IVRRIATLHGMTVSFGNAAEGGFEAVVSW
HHHHHHHHHCCEEECCCCCCCCHHHHCCC
>Mature Secondary Structure
MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELFDTQLMLFARRLSTLDL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
NEINAPQRMAHTPKKLKHGHIDDDALAFAIFSADGKMLLHDGDNGQDIPYRYRREGFDNG
HHCCCCHHHHCCHHHHCCCCCCCHHHEEEEEECCCEEEEECCCCCCCCCHHHHHCCCCCC
YLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIVAAQLTPWLIALPFMLLILLL
CCCCCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRPLVEALNQLFSRIHSMMVRERRF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKALTQLHAGIDRATRLVDQLLTLSRLD
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLNNLQDVAEISLEELLQSAVMDIYHPAQQANIDVRLQLNAHDVIRTGQPLLLSLLVRNL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEEEECHHHHHHCCHHHHHHHHHHHH
LDNAIRYSPQGSVVDVTLHARSFTVRDNGPGVAPEILTHIGERFYRPPGQSVTGSGLGLS
HHHHHHCCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHH
IVRRIATLHGMTVSFGNAAEGGFEAVVSW
HHHHHHHHHCCEEECCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]