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The map label for this gene is ygfA [H]

Identifier: 16766362

GI number: 16766362

Start: 3222350

End: 3222898

Strand: Direct

Name: ygfA [H]

Synonym: STM3061

Alternate gene names: 16766362

Gene position: 3222350-3222898 (Clockwise)

Preceding gene: 16766361

Following gene: 16766365

Centisome position: 66.34

GC content: 57.56

Gene sequence:

>549_bases
ATGATTCGGCAACGTCGCCGTGCGCTAACGCCAGAGCAGCAACGCCGTTTTGGTCAACAGGCCGCCGCCCGAATGCTCAG
CTTTCCTCCCGTCGTGATGGCGCACACTGTCGCCGTGTTTCTCTCCTTTGATGGCGAACTCGACACCCAGCCGCTGATTG
AACAGCTATGGCGAGCGGGCAAGCGCGTCTACCTTCCGGTTCTTCATCCCTTCAGCCCTGGCAACCTCCTGTTCCTGCAC
TATTATCCGCAGAGTGTGCTGGTGACCAACCGCTTAAAGATTCAGGAGCCACGGCTTGATGTCCGCGACGTATTGCCGCT
GGCAAAGCTGGATGTGCTGGTAACGCCGTTAGTCGCGTTTGACGAAGACGGGCAGCGCCTGGGGATGGGCGGCGGATTTT
ATGACCGTACGTTGCAAAACTGGCAGCAGCATAAGATCCTACCTGTGGGCTACGCGCATGATTGCCAGTTAGTGGAAAAG
TTGCCGGTTAAAGAGTGGGATATCCCGCTGCCTGCGGTGGTGACGCCGTCCAAAATTTGGGAGTGGTAG

Upstream 100 bases:

>100_bases
GTTACAGCCTGCGGCGGCATCTCGGAGATTCCCCTTCTGACTGGCGACAGCCATGACGCAACTTCCCGAACTCTCTTTAT
CACGACAAGAAATCCGCCGG

Downstream 100 bases:

>100_bases
CCGTGTTTTGTCGATTGACAGCGTCGCTTTTTTGACCTAAATTTCTCGGTGAAGGGTGAGGGAGGCGAACCTCCCTCCTG
CGTACTCACTGTTAATATGC

Product: ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MIRQRRRALTPEQQRRFGQQAAARMLSFPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVYLPVLHPFSPGNLLFLH
YYPQSVLVTNRLKIQEPRLDVRDVLPLAKLDVLVTPLVAFDEDGQRLGMGGGFYDRTLQNWQQHKILPVGYAHDCQLVEK
LPVKEWDIPLPAVVTPSKIWEW

Sequences:

>Translated_182_residues
MIRQRRRALTPEQQRRFGQQAAARMLSFPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVYLPVLHPFSPGNLLFLH
YYPQSVLVTNRLKIQEPRLDVRDVLPLAKLDVLVTPLVAFDEDGQRLGMGGGFYDRTLQNWQQHKILPVGYAHDCQLVEK
LPVKEWDIPLPAVVTPSKIWEW
>Mature_182_residues
MIRQRRRALTPEQQRRFGQQAAARMLSFPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVYLPVLHPFSPGNLLFLH
YYPQSVLVTNRLKIQEPRLDVRDVLPLAKLDVLVTPLVAFDEDGQRLGMGGGFYDRTLQNWQQHKILPVGYAHDCQLVEK
LPVKEWDIPLPAVVTPSKIWEW

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=181, Percent_Identity=27.0718232044199, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1789278, Length=182, Percent_Identity=86.8131868131868, Blast_Score=331, Evalue=1e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 21002; Mature: 21002

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRQRRRALTPEQQRRFGQQAAARMLSFPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAG
CCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHCC
KRVYLPVLHPFSPGNLLFLHYYPQSVLVTNRLKIQEPRLDVRDVLPLAKLDVLVTPLVAF
CEEEEEEECCCCCCCEEEEEECCCEEEEECCEEEECCCCCHHHHCHHHHHHHHHHHHHEE
DEDGQRLGMGGGFYDRTLQNWQQHKILPVGYAHDCQLVEKLPVKEWDIPLPAVVTPSKIW
CCCCCEECCCCCHHHHHHHHHHHCCEEECCCCCHHHHHHHCCCCCCCCCCCCEECHHHHC
EW
CC
>Mature Secondary Structure
MIRQRRRALTPEQQRRFGQQAAARMLSFPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAG
CCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHCC
KRVYLPVLHPFSPGNLLFLHYYPQSVLVTNRLKIQEPRLDVRDVLPLAKLDVLVTPLVAF
CEEEEEEECCCCCCCEEEEEECCCEEEEECCEEEECCCCCHHHHCHHHHHHHHHHHHHEE
DEDGQRLGMGGGFYDRTLQNWQQHKILPVGYAHDCQLVEKLPVKEWDIPLPAVVTPSKIW
CCCCCEECCCCCHHHHHHHHHHHCCEEECCCCCHHHHHHHCCCCCCCCCCCCEECHHHHC
EW
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]