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The map label for this gene is pphB

Identifier: 16766213

GI number: 16766213

Start: 3048771

End: 3049427

Strand: Direct

Name: pphB

Synonym: STM2907

Alternate gene names: 16766213

Gene position: 3048771-3049427 (Clockwise)

Preceding gene: 16766211

Following gene: 16766215

Centisome position: 62.77

GC content: 41.55

Gene sequence:

>657_bases
ATGGAATTAATTCGTTATGCTGACATCAACAGCGATCTCTATCGCCACATTTGGGTCGTTGGTGATATTCATGGATGTTA
CTCCTTATTGTTAACCAGACTGGCTCAATTAAATTTCTCTCCTGATACCGATCTCTTGATCTCCACTGGAGATAACATTG
ATCGAGGAAAAGAAAACCTTGAAACACTGAGACTGTTAAATACCCCATGGTTTATTTCTGTAGTGGGTAATCATGAAGCT
ATGGCGCTTGACGCTTTTGAAACACAGGATGGCAATTTCTGGTATGTAAACGGTGGTTACTGGTACGACTCGGTCACCGA
AAAAGACAGGCAAGAAGCCACTGAGCTATTACTAACTTTTAAGCAGCGTCCTCACATCATAGAAGTTGAAACGTCCTCAA
AGAAGTACGTGATTGCCCATGCCGATTATCCAGATGACAGCTACGATTATGGGAAGCAAGTTGATATTGATAGCGTTCTA
TGGTCACGCGATCGTCTGCTTGGTTCGTTACAGGGGAATATCCATCCAATACGCGGTGCGGATACTTTTATCTTCGGCCA
TATGATTGTTGACTACACAACAACATTCGCCAATCAAATCTACATTGACACCGGTTCTTTCTGTTCAGGCAATCTGTCTT
TTTTTAAAATAAAGTAA

Upstream 100 bases:

>100_bases
TAGGATATTTTAATAACTGTATATTTTAAACAATAAAAATTAATATTGGCCTACTTTTTTGTTATAATACCAGACTCCAA
AATTGTGCTATAGGAACATC

Downstream 100 bases:

>100_bases
TCTGGAAATAGAATTATATAATATCAACCCTCCCTGCATTATGGGCAATGATATAGCCTTCAATAAGTACCATTGCCCAT
TCGTAATAGCGTCTAAATTT

Product: serine/threonine-specific protein phosphatase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MELIRYADINSDLYRHIWVVGDIHGCYSLLLTRLAQLNFSPDTDLLISTGDNIDRGKENLETLRLLNTPWFISVVGNHEA
MALDAFETQDGNFWYVNGGYWYDSVTEKDRQEATELLLTFKQRPHIIEVETSSKKYVIAHADYPDDSYDYGKQVDIDSVL
WSRDRLLGSLQGNIHPIRGADTFIFGHMIVDYTTTFANQIYIDTGSFCSGNLSFFKIK

Sequences:

>Translated_218_residues
MELIRYADINSDLYRHIWVVGDIHGCYSLLLTRLAQLNFSPDTDLLISTGDNIDRGKENLETLRLLNTPWFISVVGNHEA
MALDAFETQDGNFWYVNGGYWYDSVTEKDRQEATELLLTFKQRPHIIEVETSSKKYVIAHADYPDDSYDYGKQVDIDSVL
WSRDRLLGSLQGNIHPIRGADTFIFGHMIVDYTTTFANQIYIDTGSFCSGNLSFFKIK
>Mature_218_residues
MELIRYADINSDLYRHIWVVGDIHGCYSLLLTRLAQLNFSPDTDLLISTGDNIDRGKENLETLRLLNTPWFISVVGNHEA
MALDAFETQDGNFWYVNGGYWYDSVTEKDRQEATELLLTFKQRPHIIEVETSSKKYVIAHADYPDDSYDYGKQVDIDSVL
WSRDRLLGSLQGNIHPIRGADTFIFGHMIVDYTTTFANQIYIDTGSFCSGNLSFFKIK

Specific function: Can hydrolyze phosphorylated Ser-, Thr- or Tyr- substrates in vitro. The natural substrate is unknown

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPP phosphatase family. PP-1 subfamily

Homologues:

Organism=Escherichia coli, GI1789090, Length=218, Percent_Identity=60.091743119266, Blast_Score=268, Evalue=3e-73,
Organism=Escherichia coli, GI87081988, Length=213, Percent_Identity=43.1924882629108, Blast_Score=185, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRP2_SALTY (Q8ZMH3)

Other databases:

- EMBL:   AY049951
- EMBL:   AE006468
- RefSeq:   NP_461828.1
- ProteinModelPortal:   Q8ZMH3
- SMR:   Q8ZMH3
- PptaseDB:   P3D0411149
- GeneID:   1254430
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM2907
- HOGENOM:   HBG724457
- OMA:   GDEYQFG
- ProtClustDB:   PRK09968
- BioCyc:   STYP99287:STM2907-MONOMER
- BRENDA:   3.1.3.16
- InterPro:   IPR004843
- InterPro:   IPR006186
- PANTHER:   PTHR11668

Pfam domain/function: PF00149 Metallophos

EC number: =3.1.3.16

Molecular weight: Translated: 25025; Mature: 25025

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00125 SER_THR_PHOSPHATASE

Important sites: ACT_SITE 78-78

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELIRYADINSDLYRHIWVVGDIHGCYSLLLTRLAQLNFSPDTDLLISTGDNIDRGKENL
CCEEEEECCCCCCEEEEEEEECHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHH
ETLRLLNTPWFISVVGNHEAMALDAFETQDGNFWYVNGGYWYDSVTEKDRQEATELLLTF
HHEEEECCCEEEEEECCCCEEEEEEEECCCCCEEEECCCEEECCCCHHHHHHHHHHHHHH
KQRPHIIEVETSSKKYVIAHADYPDDSYDYGKQVDIDSVLWSRDRLLGSLQGNIHPIRGA
CCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCC
DTFIFGHMIVDYTTTFANQIYIDTGSFCSGNLSFFKIK
CEEEEEHHEEHHHEHHCCEEEEECCCCCCCCEEEEEEC
>Mature Secondary Structure
MELIRYADINSDLYRHIWVVGDIHGCYSLLLTRLAQLNFSPDTDLLISTGDNIDRGKENL
CCEEEEECCCCCCEEEEEEEECHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHH
ETLRLLNTPWFISVVGNHEAMALDAFETQDGNFWYVNGGYWYDSVTEKDRQEATELLLTF
HHEEEECCCEEEEEECCCCEEEEEEEECCCCCEEEECCCEEECCCCHHHHHHHHHHHHHH
KQRPHIIEVETSSKKYVIAHADYPDDSYDYGKQVDIDSVLWSRDRLLGSLQGNIHPIRGA
CCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCC
DTFIFGHMIVDYTTTFANQIYIDTGSFCSGNLSFFKIK
CEEEEEHHEEHHHEHHCCEEEEECCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11717262; 11677609