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The map label for this gene is sgrR [H]

Identifier: 16766071

GI number: 16766071

Start: 2897643

End: 2899322

Strand: Direct

Name: sgrR [H]

Synonym: STM2759

Alternate gene names: 16766071

Gene position: 2897643-2899322 (Clockwise)

Preceding gene: 16766066

Following gene: 16766072

Centisome position: 59.65

GC content: 57.02

Gene sequence:

>1680_bases
ATGAGTATCTTCGAGGCGCATTTTCGCAGGCTGCACGCCCGCTACGGCGCAGGTCAGACGCACGAATTACAGATGCAGGA
GATCGCCGCCATCTTCGGCTGTTCGGTGCGTAATTGTCGTATTGCGCTAAAAAAGATGCATCAGGAAAAATGGCTCGACT
GGCAGCCCCAGCGCGGGCGCGGCAAGCGCTCACGGCTCCATCTGTTAACCTCGCCGGAAAAGCTGTTCAGCCAGAACGTC
AATAAGCTGCTGGAGAAGCAGGATTACGGCAACGTGCTGCGGTTTATCGGCAACGACAAGTATCTGCTGGATCGCCTGAG
CCTGTGGCGCTTTGGGGTACAGGATAAAAGCAGCGAAACGCGGGTACGCATCCCCTACTATCGCAATCTGGATCCGCTTA
ACCCACTCGTCCCCCTGCGGCGGACCGAACGCCACCTTCTGCGCCAGTGCCTGAGCGGACTGACGCGCTATGACGCCGTT
CAGGGCAGGATCGTCCCCGATATCGCCCACTACTGGACCCATAACGAGGACTTTACCCGCTGGGAGTTCTGGCTAAAATC
CACCGCCCGCTTTGCCGATGGCTGTGAGCTGGATGCCAGCGCCGTTCAGCGCTGCCTGCTCGCCGCCAGCCAGAGCCCGC
AGTTCGCGCCGATTTTCAGCCCAATCAAAACCATTACCGCTGACGCCCCCTGGCATCTGGTAATTGAAACGCATCATCCG
GTCAGACGGCTCGACTGCCTGCTCGCCACCCAGCCGACGATGCTGTTTGATTACCAGCACGGACACATCCGCTGTACCGG
CGCTTTCCACCTGCAGGAGCACAGCGACAATTTTATGGTTTTGCGGCGCAATCAACACTGGCATCAGGCGCGCCCCGGAC
TGGATGAGATCACCATTTTCACCTGGGCTCCGGAGCATATCAGCATGAGCTTTATTCCCCTGCTGCGGGGCGAAGAGGTG
CAGGATGACCGCCCGCTCAACGAGCGTAGTCTGGAGCAGAGCTGCTGCTTTGTGCTGCTCGACGGTGACGGTGCCTTTGC
AGATGAGGCCGGAAGACGGTTTATCAATTACCTGCTGCAACCTGTCGAACTCCTCAGCCAGACGCAGCTTCCCGACGAAT
ACGCACGCATCCTCTCTGTGGCTCAGGGTATGCTGCCGCAGTGGAATCACCGCCCGGTAGATTTTGGCGGGATCACAGCG
CCGTTTAACCTGCGTCAGCCGGTTATTATCAGCACCTTTCAGCAACCGGAACTGGTGGAGCTTGCCGGAGCAATTCGCCG
CCTGCTTGAACGCTGGCATATTCGCGCCGAAATACGGATCGACGCATTTGACCACTTTAACAACCAGCTGCGCCCTCCCG
CGGATATCTGGCTCAGCAACTTTATGCTCGATACCCTTTCGGTTCCGGCATTTCTGGAATGGCTAGCTTCCACCGCGCTG
TTTACACGACTGCCTGAATCCCAGCGACAAAACCTGAACGCGCTGTTACCGACGATTCTAAACAGCGACGATGAACAGGC
GTTCGCTACCATTGCCGCCTTTTTCCATGAGATGACCCACCAGCGATATGTCATTCCTTTGCTGCATCACTGGATGGAAT
TTGCGACTGAGAAGTCATTTACCTGGCGGGATTTAAATACGCTGGGATGGCCGGATTTCAGCCAACTTTGGCTCGAATAA

Upstream 100 bases:

>100_bases
CCGGTTTTCGCTTAAAACCGGAAAATTTATGAGGGCAATCACGCCAGATACCGTCAGAAAGGGATAAAAGAGGAAATCGC
GTTCGGCGGGAGGCCATCAT

Downstream 100 bases:

>100_bases
TGCTACGCCCGCAAAAGCTCGCTAAAGGGCCTTTAAAGGCCTTTAAGGGTAAGGGAGATAAGTGCGCCATTGTGGCTGTC
AATTCGTTTTGTTTAGCTCT

Product: dipeptide/oligopeptide/nickel ABC-type transport system periplasmic component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 558

Protein sequence:

>559_residues
MSIFEAHFRRLHARYGAGQTHELQMQEIAAIFGCSVRNCRIALKKMHQEKWLDWQPQRGRGKRSRLHLLTSPEKLFSQNV
NKLLEKQDYGNVLRFIGNDKYLLDRLSLWRFGVQDKSSETRVRIPYYRNLDPLNPLVPLRRTERHLLRQCLSGLTRYDAV
QGRIVPDIAHYWTHNEDFTRWEFWLKSTARFADGCELDASAVQRCLLAASQSPQFAPIFSPIKTITADAPWHLVIETHHP
VRRLDCLLATQPTMLFDYQHGHIRCTGAFHLQEHSDNFMVLRRNQHWHQARPGLDEITIFTWAPEHISMSFIPLLRGEEV
QDDRPLNERSLEQSCCFVLLDGDGAFADEAGRRFINYLLQPVELLSQTQLPDEYARILSVAQGMLPQWNHRPVDFGGITA
PFNLRQPVIISTFQQPELVELAGAIRRLLERWHIRAEIRIDAFDHFNNQLRPPADIWLSNFMLDTLSVPAFLEWLASTAL
FTRLPESQRQNLNALLPTILNSDDEQAFATIAAFFHEMTHQRYVIPLLHHWMEFATEKSFTWRDLNTLGWPDFSQLWLE

Sequences:

>Translated_559_residues
MSIFEAHFRRLHARYGAGQTHELQMQEIAAIFGCSVRNCRIALKKMHQEKWLDWQPQRGRGKRSRLHLLTSPEKLFSQNV
NKLLEKQDYGNVLRFIGNDKYLLDRLSLWRFGVQDKSSETRVRIPYYRNLDPLNPLVPLRRTERHLLRQCLSGLTRYDAV
QGRIVPDIAHYWTHNEDFTRWEFWLKSTARFADGCELDASAVQRCLLAASQSPQFAPIFSPIKTITADAPWHLVIETHHP
VRRLDCLLATQPTMLFDYQHGHIRCTGAFHLQEHSDNFMVLRRNQHWHQARPGLDEITIFTWAPEHISMSFIPLLRGEEV
QDDRPLNERSLEQSCCFVLLDGDGAFADEAGRRFINYLLQPVELLSQTQLPDEYARILSVAQGMLPQWNHRPVDFGGITA
PFNLRQPVIISTFQQPELVELAGAIRRLLERWHIRAEIRIDAFDHFNNQLRPPADIWLSNFMLDTLSVPAFLEWLASTAL
FTRLPESQRQNLNALLPTILNSDDEQAFATIAAFFHEMTHQRYVIPLLHHWMEFATEKSFTWRDLNTLGWPDFSQLWLE
>Mature_558_residues
SIFEAHFRRLHARYGAGQTHELQMQEIAAIFGCSVRNCRIALKKMHQEKWLDWQPQRGRGKRSRLHLLTSPEKLFSQNVN
KLLEKQDYGNVLRFIGNDKYLLDRLSLWRFGVQDKSSETRVRIPYYRNLDPLNPLVPLRRTERHLLRQCLSGLTRYDAVQ
GRIVPDIAHYWTHNEDFTRWEFWLKSTARFADGCELDASAVQRCLLAASQSPQFAPIFSPIKTITADAPWHLVIETHHPV
RRLDCLLATQPTMLFDYQHGHIRCTGAFHLQEHSDNFMVLRRNQHWHQARPGLDEITIFTWAPEHISMSFIPLLRGEEVQ
DDRPLNERSLEQSCCFVLLDGDGAFADEAGRRFINYLLQPVELLSQTQLPDEYARILSVAQGMLPQWNHRPVDFGGITAP
FNLRQPVIISTFQQPELVELAGAIRRLLERWHIRAEIRIDAFDHFNNQLRPPADIWLSNFMLDTLSVPAFLEWLASTALF
TRLPESQRQNLNALLPTILNSDDEQAFATIAAFFHEMTHQRYVIPLLHHWMEFATEKSFTWRDLNTLGWPDFSQLWLE

Specific function: Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding

COG id: COG4533

COG function: function code R; ABC-type uncharacterized transport system, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786256, Length=555, Percent_Identity=26.6666666666667, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1786650, Length=554, Percent_Identity=24.7292418772563, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 65353; Mature: 65222

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFEAHFRRLHARYGAGQTHELQMQEIAAIFGCSVRNCRIALKKMHQEKWLDWQPQRGR
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC
GKRSRLHLLTSPEKLFSQNVNKLLEKQDYGNVLRFIGNDKYLLDRLSLWRFGVQDKSSET
CCCCEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC
RVRIPYYRNLDPLNPLVPLRRTERHLLRQCLSGLTRYDAVQGRIVPDIAHYWTHNEDFTR
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHH
WEFWLKSTARFADGCELDASAVQRCLLAASQSPQFAPIFSPIKTITADAPWHLVIETHHP
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECCCC
VRRLDCLLATQPTMLFDYQHGHIRCTGAFHLQEHSDNFMVLRRNQHWHQARPGLDEITIF
HHHHHHHHHCCCCEEEEECCCEEEEEEEEEEEECCCCEEEEECCCCHHHCCCCCCCEEEE
TWAPEHISMSFIPLLRGEEVQDDRPLNERSLEQSCCFVLLDGDGAFADEAGRRFINYLLQ
EECHHHCCEEEEECCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHH
PVELLSQTQLPDEYARILSVAQGMLPQWNHRPVDFGGITAPFNLRQPVIISTFQQPELVE
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHH
LAGAIRRLLERWHIRAEIRIDAFDHFNNQLRPPADIWLSNFMLDTLSVPAFLEWLASTAL
HHHHHHHHHHHHCCEEEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTRLPESQRQNLNALLPTILNSDDEQAFATIAAFFHEMTHQRYVIPLLHHWMEFATEKSF
HHHCCCHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
TWRDLNTLGWPDFSQLWLE
EECCCCCCCCCCHHHHHCC
>Mature Secondary Structure 
SIFEAHFRRLHARYGAGQTHELQMQEIAAIFGCSVRNCRIALKKMHQEKWLDWQPQRGR
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC
GKRSRLHLLTSPEKLFSQNVNKLLEKQDYGNVLRFIGNDKYLLDRLSLWRFGVQDKSSET
CCCCEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC
RVRIPYYRNLDPLNPLVPLRRTERHLLRQCLSGLTRYDAVQGRIVPDIAHYWTHNEDFTR
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHH
WEFWLKSTARFADGCELDASAVQRCLLAASQSPQFAPIFSPIKTITADAPWHLVIETHHP
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECCCC
VRRLDCLLATQPTMLFDYQHGHIRCTGAFHLQEHSDNFMVLRRNQHWHQARPGLDEITIF
HHHHHHHHHCCCCEEEEECCCEEEEEEEEEEEECCCCEEEEECCCCHHHCCCCCCCEEEE
TWAPEHISMSFIPLLRGEEVQDDRPLNERSLEQSCCFVLLDGDGAFADEAGRRFINYLLQ
EECHHHCCEEEEECCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHH
PVELLSQTQLPDEYARILSVAQGMLPQWNHRPVDFGGITAPFNLRQPVIISTFQQPELVE
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHH
LAGAIRRLLERWHIRAEIRIDAFDHFNNQLRPPADIWLSNFMLDTLSVPAFLEWLASTAL
HHHHHHHHHHHHCCEEEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTRLPESQRQNLNALLPTILNSDDEQAFATIAAFFHEMTHQRYVIPLLHHWMEFATEKSF
HHHCCCHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
TWRDLNTLGWPDFSQLWLE
EECCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA