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The map label for this gene is yfhA [H]

Identifier: 16765882

GI number: 16765882

Start: 2704074

End: 2705411

Strand: Reverse

Name: yfhA [H]

Synonym: STM2562

Alternate gene names: 16765882

Gene position: 2705411-2704074 (Counterclockwise)

Preceding gene: 16765883

Following gene: 16765881

Centisome position: 55.7

GC content: 55.46

Gene sequence:

>1338_bases
ATGATAAGCCGTAAACCGGCGCACCTGCTGCTGGTCGATGACGATCCCGGATTACTGAAATTGCTCGGTATGCGCCTGAC
CAGTGAAGGATACAGCGTCGTGACCGCAGAGAGCGGCCAGGAAGGACTACGGGTACTACATCGGGAAAAAGTGGATCTGG
TAATAAGCGACCTGCGCATGGACGAAATGGATGGTATGCAACTGTTCACAGAAATTCAGAAAGTACAGCCGGGAATGCCG
GTTATCATTCTGACGGCGCATGGTTCTATTCCGGATGCGGTGGCCGCTACCCAGAAAGGCGTATTCAGCTTTTTGACGAA
GCCGATCGACAGAGACGCGTTATATAAAGCGATAGATGAAGCGCTGGAGCAGTCCGCTCCCGCGACGGACGATAGCTGGC
GCAACGCTATCGTTACCCGTAGCCCGCTGATGCTGCGACTGCTTGAACAGGCGCGCATGGTCGCGCAGTCGGATGTCAGC
GTATTGATTAACGGACAAAGCGGCACCGGGAAAGAGATTTTCGCACAGGCGATTCATAATGCCAGCCCGCGCAGTAACAA
GCCGTTTGTCGCCATTAACTGCGGCGCGTTACCGGAACAGTTGCTGGAGTCCGAATTATTCGGCCATGCGCGCGGCGCCT
TTACCGGCGCAGTGAGCAATCGTGAAGGGTTGTTCCAGGCGGCGGAAGGCGGCACGCTGTTTCTGGATGAAATTGGCGAT
ATGCCCGCGCCGTTACAGGTGAAGCTGCTGCGGGTGTTACAGGAGCGCAAAGTCAGGCCGCTGGGCAGCAATCGCGATAT
TGATATCGACGTGCGAATTATTTCCGCGACGCACCGCGATCTGCCGAAGGCGATGGCGCGGGGCGAATTTCGTGAAGATT
TGTACTACCGGCTGAATGTCGTGAGCCTGAAAATTCCGGCGCTGGCGGAGCGTACCGAGGATATTCCGCTGCTGGCTAAT
CATCTGCTCAGACAGTCGGCACAGCGGCATAAACCGTTTGTTCGCGCCTTTTCTACTGATGCAATGAAACGGCTGATGAC
GGCAAGCTGGCCGGGCAACGTGCGCCAACTGGTCAACGTCATTGAACAATGCGTGGCGTTAACTTCTTCGCCGGTGATCA
GCGATGCGTTGGTCGAGCAGGCGCTGGAAGGCGAAAACACCGCGCTGCCAACTTTTGCCGAAGCGCGAAACCAATTTGAA
CTGAACTATCTGCGCAAGTTACTGCAAATTACCAAAGGTAACGTGACGCACGCGGCAAGGATGGCGGGGCGCAACCGCAC
GGAATTCTATAAGCTACTCTCCCGTCACGAACTGGATGCGAATGATTTCAAAGAGTAG

Upstream 100 bases:

>100_bases
CGGCAGGGAATTACAACGCCGATACGCCGCATACGAATGACAAACCCGCGACGTCTGAAGATGGCGCGGCGCCGTCGCCG
TCACAAGATGAGGTAACGCC

Downstream 100 bases:

>100_bases
TTTTCATGCCGTAAAGTAGCGCGAAATATGTTACGTTTAACCGATCAAAACACAGGCGACCTTTTCAAGGAATAGCATGA
AAAAGATTGATGCGATTATT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MISRKPAHLLLVDDDPGLLKLLGMRLTSEGYSVVTAESGQEGLRVLHREKVDLVISDLRMDEMDGMQLFTEIQKVQPGMP
VIILTAHGSIPDAVAATQKGVFSFLTKPIDRDALYKAIDEALEQSAPATDDSWRNAIVTRSPLMLRLLEQARMVAQSDVS
VLINGQSGTGKEIFAQAIHNASPRSNKPFVAINCGALPEQLLESELFGHARGAFTGAVSNREGLFQAAEGGTLFLDEIGD
MPAPLQVKLLRVLQERKVRPLGSNRDIDIDVRIISATHRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLAN
HLLRQSAQRHKPFVRAFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTFAEARNQFE
LNYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRHELDANDFKE

Sequences:

>Translated_445_residues
MISRKPAHLLLVDDDPGLLKLLGMRLTSEGYSVVTAESGQEGLRVLHREKVDLVISDLRMDEMDGMQLFTEIQKVQPGMP
VIILTAHGSIPDAVAATQKGVFSFLTKPIDRDALYKAIDEALEQSAPATDDSWRNAIVTRSPLMLRLLEQARMVAQSDVS
VLINGQSGTGKEIFAQAIHNASPRSNKPFVAINCGALPEQLLESELFGHARGAFTGAVSNREGLFQAAEGGTLFLDEIGD
MPAPLQVKLLRVLQERKVRPLGSNRDIDIDVRIISATHRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLAN
HLLRQSAQRHKPFVRAFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTFAEARNQFE
LNYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRHELDANDFKE
>Mature_445_residues
MISRKPAHLLLVDDDPGLLKLLGMRLTSEGYSVVTAESGQEGLRVLHREKVDLVISDLRMDEMDGMQLFTEIQKVQPGMP
VIILTAHGSIPDAVAATQKGVFSFLTKPIDRDALYKAIDEALEQSAPATDDSWRNAIVTRSPLMLRLLEQARMVAQSDVS
VLINGQSGTGKEIFAQAIHNASPRSNKPFVAINCGALPEQLLESELFGHARGAFTGAVSNREGLFQAAEGGTLFLDEIGD
MPAPLQVKLLRVLQERKVRPLGSNRDIDIDVRIISATHRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLAN
HLLRQSAQRHKPFVRAFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTFAEARNQFE
LNYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRHELDANDFKE

Specific function: Probable member of a two-component regulatory system yfhA/yfhK [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=444, Percent_Identity=95.045045045045, Blast_Score=849, Evalue=0.0,
Organism=Escherichia coli, GI1790437, Length=439, Percent_Identity=44.874715261959, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1788550, Length=454, Percent_Identity=40.3083700440529, Blast_Score=324, Evalue=8e-90,
Organism=Escherichia coli, GI1790299, Length=464, Percent_Identity=38.1465517241379, Blast_Score=301, Evalue=6e-83,
Organism=Escherichia coli, GI87082117, Length=232, Percent_Identity=55.1724137931034, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1789087, Length=313, Percent_Identity=46.9648562300319, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1789233, Length=252, Percent_Identity=48.015873015873, Blast_Score=237, Evalue=9e-64,
Organism=Escherichia coli, GI87082152, Length=316, Percent_Identity=40.5063291139241, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI1786524, Length=377, Percent_Identity=38.9920424403183, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI87081872, Length=322, Percent_Identity=37.2670807453416, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1787583, Length=239, Percent_Identity=42.6778242677824, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1789828, Length=282, Percent_Identity=36.8794326241135, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI87081858, Length=314, Percent_Identity=33.4394904458599, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI145693157, Length=110, Percent_Identity=34.5454545454545, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49359; Mature: 49359

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISRKPAHLLLVDDDPGLLKLLGMRLTSEGYSVVTAESGQEGLRVLHREKVDLVISDLRM
CCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCC
DEMDGMQLFTEIQKVQPGMPVIILTAHGSIPDAVAATQKGVFSFLTKPIDRDALYKAIDE
CCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ALEQSAPATDDSWRNAIVTRSPLMLRLLEQARMVAQSDVSVLINGQSGTGKEIFAQAIHN
HHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHC
ASPRSNKPFVAINCGALPEQLLESELFGHARGAFTGAVSNREGLFQAAEGGTLFLDEIGD
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHCCCCCCCCCEEECCCCEEEHHHHCC
MPAPLQVKLLRVLQERKVRPLGSNRDIDIDVRIISATHRDLPKAMARGEFREDLYYRLNV
CCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHCCCHHHHHHHEEEE
VSLKIPALAERTEDIPLLANHLLRQSAQRHKPFVRAFSTDAMKRLMTASWPGNVRQLVNV
EEEECCHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IEQCVALTSSPVISDALVEQALEGENTALPTFAEARNQFELNYLRKLLQITKGNVTHAAR
HHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCHHHHHH
MAGRNRTEFYKLLSRHELDANDFKE
HHCCCHHHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure
MISRKPAHLLLVDDDPGLLKLLGMRLTSEGYSVVTAESGQEGLRVLHREKVDLVISDLRM
CCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCC
DEMDGMQLFTEIQKVQPGMPVIILTAHGSIPDAVAATQKGVFSFLTKPIDRDALYKAIDE
CCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ALEQSAPATDDSWRNAIVTRSPLMLRLLEQARMVAQSDVSVLINGQSGTGKEIFAQAIHN
HHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHC
ASPRSNKPFVAINCGALPEQLLESELFGHARGAFTGAVSNREGLFQAAEGGTLFLDEIGD
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHCCCCCCCCCEEECCCCEEEHHHHCC
MPAPLQVKLLRVLQERKVRPLGSNRDIDIDVRIISATHRDLPKAMARGEFREDLYYRLNV
CCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHCCCHHHHHHHEEEE
VSLKIPALAERTEDIPLLANHLLRQSAQRHKPFVRAFSTDAMKRLMTASWPGNVRQLVNV
EEEECCHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IEQCVALTSSPVISDALVEQALEGENTALPTFAEARNQFELNYLRKLLQITKGNVTHAAR
HHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCHHHHHH
MAGRNRTEFYKLLSRHELDANDFKE
HHCCCHHHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]