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The map label for this gene is sinH [H]

Identifier: 16765837

GI number: 16765837

Start: 2648609

End: 2650801

Strand: Reverse

Name: sinH [H]

Synonym: STM2517

Alternate gene names: 16765837

Gene position: 2650801-2648609 (Counterclockwise)

Preceding gene: 16765838

Following gene: 16765836

Centisome position: 54.57

GC content: 52.17

Gene sequence:

>2193_bases
ATGGTGCGAAGGATTCGCATTCTGGTTTTGCTATTAGTGTCTGGAGTCTCAGTTGCGGCTTCTGGCGCAGATAACTCTGC
ATCTGCAAATGATGAAAGCCACTCCTCCCTGCCTGATTTAGCCAGCGAATCCGCGAAAAAAGAAGAACAGGAAAATAAAG
GAAAGTCCTTTAAAGAACAGGGCGCTGACTACTTTATTAATTCCGCCACCCAGGGCTTTGATAATCTCACCCCGGAAGCG
CTGGAATCCCAGGCGCGTAGCTATTTGCAAAACCAAATCACTTCCTCAGCACAGTCATATCTTGAAGGTGTAATGTCACC
TTATGGCAAGATCCGTACCAGCCTGTCCGTGGGCGAAGGCGGCGATCTGGACGGCAGTTCGCTGGATTATTTTATTCCCT
GGTATGACAACCAGAGCACGCTTTTCTTTAGCCAGATTTCGGCTCAGCGTAAGGAAGACCGCACCATTGGTAACTTTGGG
CTTGGCGTTCGCCAGAACGTCGGCAACTGGCTGCTTGGCGGCAACGCATTCTATGACTACGATTTTACGCGCGGTCACCG
TCGATTAGGTCTGGGAACTGAAGCCTGGACGGATTACCTGAAATTCTCCGGCAACTATTACCATCCTCTTTCTGACTGGA
AAGACTCCGAAGATTTCGACTTTTATGAAGAACGACCCGCGCGCGGCTGGGATATCCGCATGGAAAGCTGGCTGCCGTTT
TATCCGCAGCTTGGCGCTAAATTAGTTTACGAACAGTACTACGGCGATGAAGTAGCGCTGTTTGGCACCGATAATCTGCA
AAAAGATCCTCATGCCGTCACTTTGGGGCTGGAATATACGCCGGTACCGCTGGTCACGGTTGGTACGGATTACAAAGCCG
GTACTGGCGATAGTAACGACTTTAGCGTTAACGCGACCGTGAACTACCAGATAGGCACGCCGCTGGCGGCGCAGCTCGAT
CCGGAAAACGTTAAAATTCAGCACTCCTTAATGGGCAGCCGCACCGATTTTGTCGATCGTAACAATTTCATCATTCTCGA
ATATCGTGAGAAAGATCCGCTGGACGTCACGTTGTGGCTGAAGGCTGACGCCACCAATGAACACCCGGAATGCGTGATTG
AAGATACGCCTGAGGCCGCTGTTGGTCTGGAAAAGTGCAAATGGACTGTCAACGCGCTGATTAACCACCATTACAAAATT
ATTTCTGCCTCCTGGCAGGCGAAAAACAACGCCGCCCGTACGCTGGTGATGCCGGTGGTAAAAGCTAATGCGTTAACCGA
AGGCAACAATAACAGCTGGAATCTGGTGCTTCCTGCCTGGGTTAATGCCGATACCGAAGAGCAGCGCACCGCCCTGAACA
CCTGGAAAGTACGCATGACGCTGGAAGATGAAAAGGGCAATAAGCAGAACTCCGGCGTGGTGGAAATCACCGTCCAGCAG
GATCGCAAAATTGAGCTGATCGTCGACAACATTGCCGATACCGATCGCAGCGATCACAGCCATGAAGCCAGCGCGCTGGC
CGATGGCGAAGACGGCGTGGTGATGGATCTGCTGATCACCGATTCCTTTGGCGACTCCACGGATCGCAATGGTAACGAAC
TGGTGGACGATGCCATGACGCCCGTGTTGTACGACAGCAATGATAAAAAAGTCACCCTGGCCCAGACGCCCTGCACCACG
GAAACCCCCTGCGTGTTTATTGCCAGTCGTGACAAAGAAGCGGGGACGGTGACGCTTTCCAGCACCCTGCCGGGGACTTT
CCGCTGGAAGGCGAAAGCAGACGCCTATGGCGACAGTAACTACGTTGATGTCACTTTTATCGGCGACAACCTGAGCGCGC
TGAATGCGGTGATTTATCAGGTCAAAGCCGCCAACCCTGTCAACCTTATCGGCAAAGAAGATAAGCACCCTACGGTCAAT
AATGCTTACCGTTTCCTGCTGTGGCGCGACAAAAATAAAGACGGCGTATTCCAGATGTCCGAGCAGCTCACGGAAGAAGA
GATGGCGCTGTACGACTACCAGTGGGAGTTTACCGGGCAGAGTACAAACGGACATACCGGCGCGCTGGCCAACACCATGA
ATGAAGATCTTGTCCTGCCAGTAACCAATAAAGAGGCGGCGCAGAAGTTTGCCGCCAATGTGGAAGATGGCGTTCAGGGT
TACGGCATACGCGTTACGTATAGTCAGAAATAG

Upstream 100 bases:

>100_bases
TTTTAGGAATATATTTAGGCCTGTTAGTTATGATTCCATCTGAATCATCCATATAATATCTTTTCATAGAGGCGTTTTTA
TTTAACGACAGGGATATCAT

Downstream 100 bases:

>100_bases
CGTCAGCGTTGTGGCTGACCAGCCAGCCGCTGAATTTTGAGAAAAAGGAGAGTCTGAATGCAAGCAACAGTAAAACGGCG
GCTGACGAAGGTCGCTTTAG

Product: intimin-like protein

Products: NA

Alternate protein names: Attaching and effacing protein; Eae protein [H]

Number of amino acids: Translated: 730; Mature: 730

Protein sequence:

>730_residues
MVRRIRILVLLLVSGVSVAASGADNSASANDESHSSLPDLASESAKKEEQENKGKSFKEQGADYFINSATQGFDNLTPEA
LESQARSYLQNQITSSAQSYLEGVMSPYGKIRTSLSVGEGGDLDGSSLDYFIPWYDNQSTLFFSQISAQRKEDRTIGNFG
LGVRQNVGNWLLGGNAFYDYDFTRGHRRLGLGTEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRMESWLPF
YPQLGAKLVYEQYYGDEVALFGTDNLQKDPHAVTLGLEYTPVPLVTVGTDYKAGTGDSNDFSVNATVNYQIGTPLAAQLD
PENVKIQHSLMGSRTDFVDRNNFIILEYREKDPLDVTLWLKADATNEHPECVIEDTPEAAVGLEKCKWTVNALINHHYKI
ISASWQAKNNAARTLVMPVVKANALTEGNNNSWNLVLPAWVNADTEEQRTALNTWKVRMTLEDEKGNKQNSGVVEITVQQ
DRKIELIVDNIADTDRSDHSHEASALADGEDGVVMDLLITDSFGDSTDRNGNELVDDAMTPVLYDSNDKKVTLAQTPCTT
ETPCVFIASRDKEAGTVTLSSTLPGTFRWKAKADAYGDSNYVDVTFIGDNLSALNAVIYQVKAANPVNLIGKEDKHPTVN
NAYRFLLWRDKNKDGVFQMSEQLTEEEMALYDYQWEFTGQSTNGHTGALANTMNEDLVLPVTNKEAAQKFAANVEDGVQG
YGIRVTYSQK

Sequences:

>Translated_730_residues
MVRRIRILVLLLVSGVSVAASGADNSASANDESHSSLPDLASESAKKEEQENKGKSFKEQGADYFINSATQGFDNLTPEA
LESQARSYLQNQITSSAQSYLEGVMSPYGKIRTSLSVGEGGDLDGSSLDYFIPWYDNQSTLFFSQISAQRKEDRTIGNFG
LGVRQNVGNWLLGGNAFYDYDFTRGHRRLGLGTEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRMESWLPF
YPQLGAKLVYEQYYGDEVALFGTDNLQKDPHAVTLGLEYTPVPLVTVGTDYKAGTGDSNDFSVNATVNYQIGTPLAAQLD
PENVKIQHSLMGSRTDFVDRNNFIILEYREKDPLDVTLWLKADATNEHPECVIEDTPEAAVGLEKCKWTVNALINHHYKI
ISASWQAKNNAARTLVMPVVKANALTEGNNNSWNLVLPAWVNADTEEQRTALNTWKVRMTLEDEKGNKQNSGVVEITVQQ
DRKIELIVDNIADTDRSDHSHEASALADGEDGVVMDLLITDSFGDSTDRNGNELVDDAMTPVLYDSNDKKVTLAQTPCTT
ETPCVFIASRDKEAGTVTLSSTLPGTFRWKAKADAYGDSNYVDVTFIGDNLSALNAVIYQVKAANPVNLIGKEDKHPTVN
NAYRFLLWRDKNKDGVFQMSEQLTEEEMALYDYQWEFTGQSTNGHTGALANTMNEDLVLPVTNKEAAQKFAANVEDGVQG
YGIRVTYSQK
>Mature_730_residues
MVRRIRILVLLLVSGVSVAASGADNSASANDESHSSLPDLASESAKKEEQENKGKSFKEQGADYFINSATQGFDNLTPEA
LESQARSYLQNQITSSAQSYLEGVMSPYGKIRTSLSVGEGGDLDGSSLDYFIPWYDNQSTLFFSQISAQRKEDRTIGNFG
LGVRQNVGNWLLGGNAFYDYDFTRGHRRLGLGTEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRMESWLPF
YPQLGAKLVYEQYYGDEVALFGTDNLQKDPHAVTLGLEYTPVPLVTVGTDYKAGTGDSNDFSVNATVNYQIGTPLAAQLD
PENVKIQHSLMGSRTDFVDRNNFIILEYREKDPLDVTLWLKADATNEHPECVIEDTPEAAVGLEKCKWTVNALINHHYKI
ISASWQAKNNAARTLVMPVVKANALTEGNNNSWNLVLPAWVNADTEEQRTALNTWKVRMTLEDEKGNKQNSGVVEITVQQ
DRKIELIVDNIADTDRSDHSHEASALADGEDGVVMDLLITDSFGDSTDRNGNELVDDAMTPVLYDSNDKKVTLAQTPCTT
ETPCVFIASRDKEAGTVTLSSTLPGTFRWKAKADAYGDSNYVDVTFIGDNLSALNAVIYQVKAANPVNLIGKEDKHPTVN
NAYRFLLWRDKNKDGVFQMSEQLTEEEMALYDYQWEFTGQSTNGHTGALANTMNEDLVLPVTNKEAAQKFAANVEDGVQG
YGIRVTYSQK

Specific function: Necessary for the production of attaching and effacing lesions on tissue culture cells. Believed to mediate adherence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Single-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 LysM repeat [H]

Homologues:

Organism=Escherichia coli, GI145693153, Length=445, Percent_Identity=36.6292134831461, Blast_Score=263, Evalue=3e-71,
Organism=Escherichia coli, GI145693120, Length=479, Percent_Identity=32.1503131524008, Blast_Score=212, Evalue=6e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR003343
- InterPro:   IPR016186
- InterPro:   IPR016187
- InterPro:   IPR003535
- InterPro:   IPR013117
- InterPro:   IPR008964
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF02369 Big_1; PF02368 Big_2; PF07979 Intimin_C; PF01476 LysM [H]

EC number: NA

Molecular weight: Translated: 81207; Mature: 81207

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRRIRILVLLLVSGVSVAASGADNSASANDESHSSLPDLASESAKKEEQENKGKSFKEQ
CCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHC
GADYFINSATQGFDNLTPEALESQARSYLQNQITSSAQSYLEGVMSPYGKIRTSLSVGEG
CCCEEECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEECCCC
GDLDGSSLDYFIPWYDNQSTLFFSQISAQRKEDRTIGNFGLGVRQNVGNWLLGGNAFYDY
CCCCCCCCEEEEEEECCCCEEEEEHHHHHHHHCCCCCCCCCCHHHCCCCEEECCCEEEEC
DFTRGHRRLGLGTEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRMESWLPF
CCCCCCEEECCCHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHCCCCCCEEEEECCCCCC
YPQLGAKLVYEQYYGDEVALFGTDNLQKDPHAVTLGLEYTPVPLVTVGTDYKAGTGDSND
CHHHHHHEEHHHHCCCEEEEEECCCCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCC
FSVNATVNYQIGTPLAAQLDPENVKIQHSLMGSRTDFVDRNNFIILEYREKDPLDVTLWL
EEEEEEEEEEECCCEEEEECCCCEEEEEHHCCCCCCEECCCCEEEEEECCCCCCEEEEEE
KADATNEHPECVIEDTPEAAVGLEKCKWTVNALINHHYKIISASWQAKNNAARTLVMPVV
EECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEE
KANALTEGNNNSWNLVLPAWVNADTEEQRTALNTWKVRMTLEDEKGNKQNSGVVEITVQQ
ECCEEECCCCCCEEEEEEEEECCCCHHHHHEEEEEEEEEEEECCCCCCCCCCEEEEEECC
DRKIELIVDNIADTDRSDHSHEASALADGEDGVVMDLLITDSFGDSTDRNGNELVDDAMT
CCEEEEEEECCCCCCCCCCCCCHHHCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHCC
PVLYDSNDKKVTLAQTPCTTETPCVFIASRDKEAGTVTLSSTLPGTFRWKAKADAYGDSN
CEEECCCCCEEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEEECCCCCCCC
YVDVTFIGDNLSALNAVIYQVKAANPVNLIGKEDKHPTVNNAYRFLLWRDKNKDGVFQMS
EEEEEEECCCHHHHHEEEEEEECCCCEEECCCCCCCCCCCCEEEEEEEECCCCCCHHHHH
EQLTEEEMALYDYQWEFTGQSTNGHTGALANTMNEDLVLPVTNKEAAQKFAANVEDGVQG
HHHCHHHHEEEEEEEEEECCCCCCCCCHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCCC
YGIRVTYSQK
CEEEEEECCC
>Mature Secondary Structure
MVRRIRILVLLLVSGVSVAASGADNSASANDESHSSLPDLASESAKKEEQENKGKSFKEQ
CCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHC
GADYFINSATQGFDNLTPEALESQARSYLQNQITSSAQSYLEGVMSPYGKIRTSLSVGEG
CCCEEECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEECCCC
GDLDGSSLDYFIPWYDNQSTLFFSQISAQRKEDRTIGNFGLGVRQNVGNWLLGGNAFYDY
CCCCCCCCEEEEEEECCCCEEEEEHHHHHHHHCCCCCCCCCCHHHCCCCEEECCCEEEEC
DFTRGHRRLGLGTEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRMESWLPF
CCCCCCEEECCCHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHCCCCCCEEEEECCCCCC
YPQLGAKLVYEQYYGDEVALFGTDNLQKDPHAVTLGLEYTPVPLVTVGTDYKAGTGDSND
CHHHHHHEEHHHHCCCEEEEEECCCCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCC
FSVNATVNYQIGTPLAAQLDPENVKIQHSLMGSRTDFVDRNNFIILEYREKDPLDVTLWL
EEEEEEEEEEECCCEEEEECCCCEEEEEHHCCCCCCEECCCCEEEEEECCCCCCEEEEEE
KADATNEHPECVIEDTPEAAVGLEKCKWTVNALINHHYKIISASWQAKNNAARTLVMPVV
EECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEE
KANALTEGNNNSWNLVLPAWVNADTEEQRTALNTWKVRMTLEDEKGNKQNSGVVEITVQQ
ECCEEECCCCCCEEEEEEEEECCCCHHHHHEEEEEEEEEEEECCCCCCCCCCEEEEEECC
DRKIELIVDNIADTDRSDHSHEASALADGEDGVVMDLLITDSFGDSTDRNGNELVDDAMT
CCEEEEEEECCCCCCCCCCCCCHHHCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHCC
PVLYDSNDKKVTLAQTPCTTETPCVFIASRDKEAGTVTLSSTLPGTFRWKAKADAYGDSN
CEEECCCCCEEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEEECCCCCCCC
YVDVTFIGDNLSALNAVIYQVKAANPVNLIGKEDKHPTVNNAYRFLLWRDKNKDGVFQMS
EEEEEEECCCHHHHHEEEEEEECCCCEEECCCCCCCCCCCCEEEEEEEECCCCCCHHHHH
EQLTEEEMALYDYQWEFTGQSTNGHTGALANTMNEDLVLPVTNKEAAQKFAANVEDGVQG
HHHCHHHHEEEEEEEEEECCCCCCCCCHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCCC
YGIRVTYSQK
CEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9529069 [H]