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The map label for this gene is eutG

Identifier: 16765781

GI number: 16765781

Start: 2571370

End: 2572557

Strand: Reverse

Name: eutG

Synonym: STM2461

Alternate gene names: 16765781

Gene position: 2572557-2571370 (Counterclockwise)

Preceding gene: 16765782

Following gene: 16765780

Centisome position: 52.96

GC content: 62.88

Gene sequence:

>1188_bases
ATGCAAGCTGAACTACAGACGGCGCTGTTTCAGGCATTCGACACCCTGAATCTGCAACGGGTGAAAACGTTCAGCGTACC
GCCGGTCACGCTGTGCGGACTTGGGGCGCTCGGCGCCTGTGGACAGGAAGCGCAAGCGCGAGGCGTAAGCCATCTGTTTG
TGATGGTCGACAGCTTCCTGCATCAGGCGGGAATGACCGCGCCGCTGGCACGCAGCCTGGCGATGAAGGGCGTGGCGATG
ACGGTCTGGCCGTGTCCGCCTGGCGAGCCGTGCATCACCGATGTCTGCGCGGCGGTGGCGCAACTGCGTGAGGCGGCGTG
CGACGGCGTAGTGGCCTTTGGCGGCGGTTCGGTGCTGGACGCGGCGAAAGCGGTCGCCCTGCTGGTGACTAACCCTGACC
AGACGCTGAGCGCCATGACCGAGCACAGTACATTACGCCCGCGTCTGCCGCTGATTGCGGTGCCGACCACCGCCGGAACC
GGTTCTGAAACCACCAACGTAACGGTGATTATCGACGCGGTCAGCGGGCGCAAGCAGGTGCTGGCGCACGCGTCACTAAT
GCCGGACGTGGCGATTCTTGATGCTGCCGTGACCGAAGGCGTTCCGCCAAACGTGACGGCGATGACCGGTATCGATGCGT
TGACGCATGCGATTGAGGCCTACAGCGCGCTCAACGCCACGCCGTTTACCGACAGCCTGGCGATTGGCGCGATAGCGATG
ATTGGCAAATCGCTGCCGAAAGCCGTGGGTTACGGCCACGATCTGGCGGCGCGTGAAAATATGTTGCTGGCCTCCTGTAT
GGCGGGAATGGCCTTTTCCAGCGCCGGTCTGGGGCTGTGTCATGCGATGGCGCACCAGCCTGGGGCGGCGCTGCATATTC
CGCACGGCCAGGCCAACGCCATGCTGCTGCCAACAGTCATGGGCTTTAACCGGATGGTTTGCCGCGAGCGCTTCAGTCAA
ATAGGTCGGGCGTTAACCAATAAGAAATCGGACGATCGCGATGCGATTGCGGCGGTGTGCGAGCTGATTGCCGAAGTGGG
ACAGAGCAAACGGCTGGCTGACGCTGGCGCCAAACCCGAACACTACAGCGCGTGGGCGCAAGCCGCGCTGGAGGATATTT
GTCTGCGCAGTAACCCACGCACCGCCACACAGGCACAGATTATCGACCTGTACGCGGCTGCCGGGTAA

Upstream 100 bases:

>100_bases
CAGCGTTTCCCGGAGTTACAGGTGCATTTGCCGCAGCACAGCCTGTTTATGACCCCGCTGGCGATAGCCAACAGCGGGAG
AGCGAAAGCGGAGGGACTCT

Downstream 100 bases:

>100_bases
TGCCTGTAGGCCGGATAAGGTGCTCGCACCGCCATCCGGCAATAACACGGCGTTAATGCCGGAGGCGACGTAAACGTCTT
ATCCGGTTTACAAATCAAAA

Product: transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MQAELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGALGACGQEAQARGVSHLFVMVDSFLHQAGMTAPLARSLAMKGVAM
TVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLDAAKAVALLVTNPDQTLSAMTEHSTLRPRLPLIAVPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARENMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGQANAMLLPTVMGFNRMVCRERFSQ
IGRALTNKKSDDRDAIAAVCELIAEVGQSKRLADAGAKPEHYSAWAQAALEDICLRSNPRTATQAQIIDLYAAAG

Sequences:

>Translated_395_residues
MQAELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGALGACGQEAQARGVSHLFVMVDSFLHQAGMTAPLARSLAMKGVAM
TVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLDAAKAVALLVTNPDQTLSAMTEHSTLRPRLPLIAVPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARENMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGQANAMLLPTVMGFNRMVCRERFSQ
IGRALTNKKSDDRDAIAAVCELIAEVGQSKRLADAGAKPEHYSAWAQAALEDICLRSNPRTATQAQIIDLYAAAG
>Mature_395_residues
MQAELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGALGACGQEAQARGVSHLFVMVDSFLHQAGMTAPLARSLAMKGVAM
TVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLDAAKAVALLVTNPDQTLSAMTEHSTLRPRLPLIAVPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARENMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGQANAMLLPTVMGFNRMVCRERFSQ
IGRALTNKKSDDRDAIAAVCELIAEVGQSKRLADAGAKPEHYSAWAQAALEDICLRSNPRTATQAQIIDLYAAAG

Specific function: May act on the acetaldehyde produced from the degradation of ethanolamine

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family

Homologues:

Organism=Homo sapiens, GI133922590, Length=323, Percent_Identity=28.7925696594427, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI87082107, Length=394, Percent_Identity=86.5482233502538, Blast_Score=697, Evalue=0.0,
Organism=Escherichia coli, GI48994951, Length=378, Percent_Identity=35.978835978836, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI1789163, Length=372, Percent_Identity=38.1720430107527, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1787493, Length=393, Percent_Identity=31.0432569974555, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1789386, Length=296, Percent_Identity=28.0405405405405, Blast_Score=92, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17537053, Length=302, Percent_Identity=28.1456953642384, Blast_Score=114, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6321181, Length=374, Percent_Identity=33.9572192513369, Blast_Score=213, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24657991, Length=284, Percent_Identity=30.6338028169014, Blast_Score=89, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EUTG_SALTY (P41795)

Other databases:

- EMBL:   U18560
- EMBL:   AF093749
- EMBL:   AE006468
- RefSeq:   NP_461396.1
- ProteinModelPortal:   P41795
- SMR:   P41795
- GeneID:   1253983
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM2461
- NMPDR:   fig|99287.1.peg.2377
- HOGENOM:   HBG742415
- OMA:   CELIAEV
- ProtClustDB:   PRK15454
- BioCyc:   STYP99287:STM2461-MONOMER
- InterPro:   IPR001670
- InterPro:   IPR018211

Pfam domain/function: PF00465 Fe-ADH

EC number: NA

Molecular weight: Translated: 40904; Mature: 40904

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00913 ADH_IRON_1; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGALGACGQEAQARGVSHLFVMVDSFL
CCCHHHHHHHHHHHHCCHHHEEECCCCCHHHHCCCHHCCCCCHHHHCCHHHHHHHHHHHH
HQAGMTAPLARSLAMKGVAMTVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLD
HHCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHH
AAKAVALLVTNPDQTLSAMTEHSTLRPRLPLIAVPTTAGTGSETTNVTVIIDAVSGRKQV
HHHEEEEEEECCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHHHH
LAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
HHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IGKSLPKAVGYGHDLAARENMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGQANA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCCCCC
MLLPTVMGFNRMVCRERFSQIGRALTNKKSDDRDAIAAVCELIAEVGQSKRLADAGAKPE
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCH
HYSAWAQAALEDICLRSNPRTATQAQIIDLYAAAG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQAELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGALGACGQEAQARGVSHLFVMVDSFL
CCCHHHHHHHHHHHHCCHHHEEECCCCCHHHHCCCHHCCCCCHHHHCCHHHHHHHHHHHH
HQAGMTAPLARSLAMKGVAMTVWPCPPGEPCITDVCAAVAQLREAACDGVVAFGGGSVLD
HHCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHH
AAKAVALLVTNPDQTLSAMTEHSTLRPRLPLIAVPTTAGTGSETTNVTVIIDAVSGRKQV
HHHEEEEEEECCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHHHH
LAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
HHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IGKSLPKAVGYGHDLAARENMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGQANA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCCCCC
MLLPTVMGFNRMVCRERFSQIGRALTNKKSDDRDAIAAVCELIAEVGQSKRLADAGAKPE
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCH
HYSAWAQAALEDICLRSNPRTATQAQIIDLYAAAG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7868611; 10464203; 11677609